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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

NKTR Gene

protein-coding GIFtS: 52
GCID: GC03P042617

natural killer-tumor recognition sequence

Explore 3 diseases affiliated with
NKTR via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Natural Killer-Tumor Recognition Sequence¹ ²		Natural Killer Triggering Receptor²
P104¹		NK-Tumor Recognition Protein²
Natural-Killer Cells Cyclophilin-Related Protein² ³		EC 5.2.1.8⁸
NK-TR Protein² ³

External Ids:	HGNC: 7833¹	Entrez Gene: 4820²	Ensembl: ENSG00000114857⁷	OMIM: 161565⁵	UniProtKB: P30414³

Export aliases for NKTR gene to outside databases

Previous GC identifers: GC03P041946 GC03P041822 GC03P042461 GC03P042602

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NKTR:

This gene encodes a membrane-anchored protein with a hydrophobic amino terminal domain and a cyclophilin-like PPIase

domain. It is present on the surface of natural killer cells and facilitates their binding to targets. Its expression

is regulated by IL2 activation of the cells. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: NKTR_HUMAN, P30414

Function: Component of a putative tumor-recognition complex. Involved in the function of NK cells

Gene Wiki entry for NKTR

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000003.11 NC_018914.1 NT_022517.18

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the NKTR gene promoter:
HEN1 AP-4
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): NKTR promoter sequence

Search SABiosciences Chromatin IP Primers for NKTR

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NKTR

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p23-p21 Ensembl cytogenetic band: 3p22.1 HGNC cytogenetic band: 3p23-p21

NKTR Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NKTR gene location

GeneLoc information about chromosome 3 GeneLoc Exon Structure

GeneLoc location for GC03P042617: view genomic region (about GC identifiers)

Start:	42,642,106 bp from pter	End:	42,690,233 bp from pter
Size:	48,128 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: NKTR_HUMAN, P30414 (See protein sequence)

Recommended Name: NK-tumor recognition protein

Size: 1462 amino acids; 165677 Da

Subcellular location: Membrane; Peripheral membrane protein. Note=Attached to the membrane via its N-terminus

1 PDB 3D structure from and Proteopedia for NKTR:

2HE9 (3D)

Explore the universe of human proteins at neXtProt for NKTR: NX_P30414

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_P30414

3 DME Specific Peptides for NKTR (P30414)

FMIQGGD

GGESIYG

TNGSQFF

NKTR Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_005376.2

ENSEMBL proteins:

ENSP00000232978 ENSP00000404802 ENSP00000390259 ENSP00000408660

Human Recombinant Protein Products:

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	Browse ProSpec Recombinant Proteins
	Uscn Proteins for NKTR

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016020	membrane	IEA	--

NKTR for ontologies About GeneDecksing

NKTR Antibody Products:

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	Search ThermoFisher Antibodies for NKTR

Assay Products for NKTR:

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	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for NKTR

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

NKTR for domains About GeneDecksing

2 InterPro domains/families:

IPR002130 Cyclophilin-like_PPIase_dom

IPR020892 Cyclophilin-type_PPIase_CS

Graphical View of Domain Structure for InterPro Entry P30414

ProtoNet protein and cluster: P30414

1 Blocks protein family: IPB002130 Peptidyl-prolyl cis-trans isomerase

UniProtKB/Swiss-Prot: NKTR_HUMAN, P30414

Similarity: Contains 1 PPIase cyclophilin-type domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: NKTR_HUMAN, P30414

Function: Component of a putative tumor-recognition complex. Involved in the function of NK cells

Catalytic activity: Peptidylproline (omega=180) = peptidylproline (omega=0)

Genatlas biochemistry entry for NKTR:

natural killer triggering receptor

Enzyme Number (IUBMB): EC 5.2.1.8²

miRNA Products:		OriGene 3'-UTR Clone: NKTR Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NKTR
		8/58 QIAGEN miScript miRNA Assays for microRNAs that regulate NKTR (see all 58):
		hsa-miR-3607-3p hsa-miR-300 hsa-miR-513a-5p hsa-miR-29a hsa-miR-128 hsa-miR-624 hsa-miR-3653 hsa-miR-30d

		SwitchGear 3'UTR luciferase reporter plasmid: NKTR 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NKTR (see all 4) OriGene shRNA RFP: NKTR OriGene siRNA: NKTR
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Gene Editing
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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for NKTR
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NKTR

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	IEA	--
GO:0016018	cyclosporin A binding	TAS	8421688

NKTR for ontologies About GeneDecksing

Animal Models:
1 MGI phenotypic allele

for Nktr (no phenotypes)

NKTR for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for NKTR

STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

5/9 Interacting proteins for NKTR (P30414³ ENSP00000232978⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 9)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
RNPS1	Q15287³, ENSP00000315859⁴	I2D: score=3 STRING: ENSP00000315859
SUMO1	P63165³, ENSP00000376076⁴	I2D: score=1 STRING: ENSP00000376076
MAPK14	Q16539³, ENSP00000229794⁴	I2D: score=3 STRING: ENSP00000229794
JUN	P05412³	I2D: score=2
PACSIN1	Q9BY11³	I2D: score=2

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006457	protein folding	IEA	--

NKTR for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for NKTR
Search CenterWatch for drugs/clinical trials and news about NKTR

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for NKTR gene (2 alternative transcripts):

NM_005385.3 NM_001012651.1

Unigene Cluster for NKTR:

Natural killer-tumor recognition sequence

Hs.529509 [show with all ESTs]

Unigene Representative Sequence: NM_005385

18 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000232978(uc003clo.3) ENST00000468735(uc003cll.1 uc003clm.1 uc003clr.1)

ENST00000460910 ENST00000487466 ENST00000429888(uc003clp.3 uc011azp.2 uc003cls.3)

ENST00000459950 ENST00000442970 ENST00000445842 ENST00000478488 ENST00000465584(uc003clq.1)

ENST00000466553 ENST00000498730 ENST00000472127 ENST00000508351 ENST00000460807

ENST00000464315 ENST00000472258 ENST00000490189

miRNA Products:		OriGene 3'-UTR Clone: NKTR Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NKTR
		8/58 QIAGEN miScript miRNA Assays for microRNAs that regulate NKTR (see all 58):
		hsa-miR-3607-3p hsa-miR-300 hsa-miR-513a-5p hsa-miR-29a hsa-miR-128 hsa-miR-624 hsa-miR-3653 hsa-miR-30d

		SwitchGear 3'UTR luciferase reporter plasmid: NKTR 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NKTR (see all 4) OriGene shRNA RFP: NKTR OriGene siRNA: NKTR
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NKTR

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NKTR (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NKTR OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: NKTR (NM_005385)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for NKTR
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NKTR

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Additional cDNA sequence:

AK093752.1 BC020672.1 BC144518.1 L04288.2 S65996.1

24/29 DOTS entries (see all 29):

DT.120783 DT.65284018 DT.95342764 DT.99978093 DT.75167322 DT.40117505 DT.448662 DT.120780

DT.91698317 DT.85104310 DT.40312655 DT.100642471 DT.120784 DT.92428429 DT.120908207 DT.87046221

DT.100686840 DT.120908157 DT.120908170 DT.120908206 DT.86854098 DT.86859540 DT.100774721 DT.120908107

24/417 AceView cDNA sequences (see all 417):

AA910731 AA418204 S65996 BU630944 N87819 BU172607 BQ448590 AA360869

BX953963 BQ954131 N59412 BM695347 BU681160 BM680965 AU134460 AI241445

AA827808 BQ378902 BX641127 BE676092 H88838 AA490321 AA989253 AA279666

GeneLoc Exon Structure

5/11 Alternative Splicing Database (ASD) splice patterns (SP) for NKTR (see all 11) About this scheme

ExUns:	1a	·	1b	·	1c	^	2a	·	2b	^	3	^	4a	·	4b	^	5a	·	5b	^	6	^	7	^	8	^	9a	·	9b	·	9c	^	10a	·	10b	^	11	^	12a	·	12b	^	13	^	14a	·	14b	^	15	^	16	^
SP1:									-						-				-
SP2:																																	-						-
SP3:
SP4:
SP5:									-

ExUns:	17a	·	17b	^	18a	·	18b	·	18c
SP1:
SP2:
SP3:	-
SP4:	-
SP5:

ECgene alternative splicing isoforms for NKTR

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

NKTR expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAAAAGGACA

About this image
See NKTR Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NKTR

SOURCE GeneReport for Unigene cluster: Hs.529509

SABiosciences Custom PCR Arrays for NKTR

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NKTR

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for NKTR gene from 7/26 species (see all 26) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	LOC100858659¹	NK-tumor recognition protein-like	63.24(n) 57.91(a)		100858659 XM_003640672.1 XP_003640720.1
lizard (Anolis carolinensis)	Reptilia	NKTR⁶	--	64(a)	1 ↔ 1	6(2647202-2673790)
African clawed frog (Xenopus laevis)	Amphibia	BJ619911.1²	--	77.09(n)		BJ619911.1
zebrafish (Danio rerio)	Actinopterygii	nktr¹	natural killer-tumor recognition sequence	53.57(n) 49.1(a)		323005 XM_001338036.3 XP_001338072.3
fruit fly (Drosophila melanogaster)	Insecta	CG8336⁶	--	20(a)	possible ortholog	3L(9621776-9624895)
thale cress (Arabidopsis thaliana)	eudicotyledons	AT3G22920⁶ AT3G63400⁶ (see all 3)	peptidylprolyl isomerase cyclophilin-like peptidyl-prolyl cis-trans isomera... (see all 3)	31(a) 24(a) (see all 3)	possible ortholog many ↔ many (see all 3)	3(8122713-8123411) 3(23412024-23415659)
rice (Oryza sativa)	Liliopsida	--	peptidyl-prolyl cis-trans isomerase, putative, exp...	30(a)	1 → many	2(5826295-5834386)

ENSEMBL Gene Tree for NKTR (if available)
TreeFam Gene Tree for NKTR (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for NKTR gene

PPID² PPIG² PPIL6²

18/24 SIMAP similar genes for NKTR using alignment to 3 protein entries: NKTR_HUMAN (see all proteins) (see all similar genes):

DKFZp686G0426 DKFZp686J06106 DKFZp686N24126 PPIG PPID PPIL6

PPIF PPIE PPIB PPIH RANBP2 PPIL1

PPIA PPIC PPIAL4G PPIAL4A PPIAL4B PPIAL4C

NKTR for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 3 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs78167645^1,2	C,	--	42640225(+)	`CTTGGG/AAAAAG`	2	--	us2k¹ int¹		2		NA	122
rs188499306^1,2		--	42640296(+)	`TTCTGC/TGGACG`	2	--	int¹ us2k¹		0	--	--	--	--
rs138246973^1,2		--	42640316(+)	`TACTGA/CGGGTT`	2	--	us2k¹ int¹		0	--	--	--	--
rs77291243^1,2	F,	--	42640385(+)	`ATGGCA/GACTTT`	2	--	int¹ us2k¹		2		WA EA	238
rs3111313^1,2	C,	--	42640394(-)	`CATTAC/TGTGAA`	2	--	int¹ us2k¹		10		NA WA CSA EA	370
rs201375436^1,2		--	42640419(+)	`TAGAT-/CTATAG ATATC`	2	--	int¹ us2k¹		0	--	--	--	--
rs3111312^1,2	C,F,A,,	--	42640422(-)	`TATCTG/ATAGAT`	2	--	us2k¹ int¹		4		NA CSA	7
rs138069697^1,2		--	42640514(+)	`ATGCAC/GTGGAC`	2	--	us2k¹ int¹		0	--	--	--	--
rs193099999^1,2		--	42640518(+)	`AGTGGA/TCCGAT`	2	--	us2k¹ int¹		0	--	--	--	--
rs184784637^1,2		--	42640656(+)	`GTTTCA/GCCGTG`	2	--	us2k¹ int¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for NKTR (42642106 - 42690233 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for NKTR: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NKTR

DNA2.0 Custom Variant and Variant Library Synthesis for NKTR

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

NKTR for disorders           About GeneDecksing

OMIM gene information: 161565    OMIM disorders: --

3 diseases for NKTR:    About MalaCards

theileriasis constipation malaria

Export disorders for NKTR gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for NKTR gene, integrated from 9 sources (see all 19):
(articles sorted by number of sources associating them with NKTR)

Utopia: connect your pdf to the dynamic
world of online information

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{1, 2} Olsen J.V....Mann M. (2006)
Expression of the NK-TR gene is required for NK-like activity in human T cells. (PubMed id 8144875)^{1, 3} Chambers C.A....Roder J. (1994)
Localization of a novel natural killer triggering receptor locus to human chromosome 3p23-p21 and mouse chromosome 9. (PubMed id 8314596)^{1, 3} Young H.A....Anderson S.K. (1993)
A cyclophilin-related protein involved in the function of natural killer cells. (PubMed id 8421688)^{1, 2} Anderson S.K....Ortaldo J.R. (1993)
IL-2 regulates the expression of the NK-TR gene via an alternate RNA splicing mechanism. (PubMed id 8413330)^{1, 9} Rinfret A. and Anderson S.K. (1993)
System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)² Rigbolt K.T....Blagoev B. (2011)
Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)² Olsen J.V....Mann M. (2010)
A human MAP kinase interactome. (PubMed id 20936779)¹ Bandyopadhyay S....Ideker T. (2010)
Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)² Mayya V.... Han D.K. (2009)
Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)¹ Abdelmohsen K....Gorospe M. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 4820	HGNC: 7833	AceView: NKTR	Ensembl:ENSG00000114857	euGenes: HUgn4820
ECgene: NKTR	H-InvDB: NKTR

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for NKTR	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for NKTR	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for NKTR gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for NKTR gene:
Search GeneIP for patents involving NKTR

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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natural killer-tumor recognition sequence

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natural killer-tumor recognition sequence

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