Aliases for NKIRAS1 Gene
Aliases for NKIRAS1 Gene
External Ids for NKIRAS1 Gene
- HGNC: 17899
- Entrez Gene: 28512
- Ensembl: ENSG00000197885
- OMIM: 604496
- UniProtKB: Q9NYS0
Previous GeneCards Identifiers for NKIRAS1 Gene
- GC03M023908
- GC03M023933
- GC03M023879
Summaries for NKIRAS1 Gene
GeneCards Summary for NKIRAS1 Gene
NKIRAS1 (NFKB Inhibitor Interacting Ras Like 1) is a Protein Coding gene. Among its related pathways are NF-KappaB Family Pathway. Gene Ontology (GO) annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is NKIRAS2.
UniProtKB/Swiss-Prot for NKIRAS1 Gene
-
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
Additional gene information for NKIRAS1 Gene
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NKIRAS1 Gene
Genomics for NKIRAS1 Gene
GeneHancer (GH) Regulatory Elements for NKIRAS1 Gene
Promoters and enhancers for NKIRAS1 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH03I023915 | Promoter/Enhancer | 2.1 | EPDnew Ensembl ENCODE | 563.1 | +29.4 | 29377 | 4.1 | MLX ZFP64 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 | NKIRAS1 RPL15 NR1D2 | |
| GH03I023944 | Promoter/Enhancer | 2.1 | EPDnew Ensembl ENCODE | 550.8 | -0.1 | -72 | 4.6 | CLOCK MLX FEZF1 DMAP1 YY1 ZNF213 E2F8 ZNF143 SP3 NFYC | NR1D2 NKIRAS1 NPM1P23 | |
| GH03I023805 | Promoter/Enhancer | 2 | EPDnew Ensembl ENCODE | 10.5 | +137.8 | 137784 | 6.9 | PKNOX1 FOXA2 SMAD1 ARNT SIN3A DMAP1 YBX1 ZNF2 YY1 POLR2B | UBE2E1 UBE2E1-AS1 RPL15 NKIRAS1 NR1D2 GC03P023841 | |
| GH03I023829 | Enhancer | 1 | Ensembl ENCODE | 11.4 | +116.7 | 116742 | 1.1 | PKNOX1 BACH1 CHD4 BMI1 BATF IRF4 RELA ZNF121 NFATC1 ATF7 | UBE2E1-AS1 UBE2E1 NKIRAS1 NR1D2 RPL15 GC03P023841 | |
| GH03I023991 | Enhancer | 1 | Ensembl ENCODE | 11.2 | -45.5 | -45469 | 1.8 | INSM2 FEZF1 ZEB1 ZNF335 ZNF213 ZNF366 ZSCAN5C SCRT2 RCOR1 ELK4 | NKIRAS1 RPL15 NPM1P23 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around NKIRAS1 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the NKIRAS1 gene promoter:
Regulatory Element Products
Genomic Locations for NKIRAS1 Gene
Genomic Locations for NKIRAS1 Gene
- chr3:23,891,660-23,946,591
- (GRCh38/hg38)
- Size:
- 54,932 bases
- Orientation:
- Minus strand
- chr3:23,933,151-23,988,082
- (GRCh37/hg19)
Genomic View for NKIRAS1 Gene
Genes around NKIRAS1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 3p24.2 by Ensembl
- 3p24.2 by Entrez Gene
- 3p24.2 by HGNC
NKIRAS1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for NKIRAS1 Gene
Proteins for NKIRAS1 Gene
-
Protein details for NKIRAS1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9NYS0-KBRS1_HUMAN
- Recommended name:
- NF-kappa-B inhibitor-interacting Ras-like protein 1
- Protein Accession:
- Q9NYS0
- Q96K18
Protein attributes for NKIRAS1 Gene
- Size:
- 192 amino acids
- Molecular mass:
- 21643 Da
- Quaternary structure:
-
- Interacts with both NF-kappa-B inhibitor alpha (NFKBIA) and beta (NFKBIB) in vitro. However, it probably only interacts with NFKBIB in vivo. Forms a complex with NFKBIB and NF-kappa-B heterodimer (p50/NFKB1 and p65/RELA). Also interacts with c-Rel (REL).
Protein Expression for NKIRAS1 Gene
Post-translational modifications for NKIRAS1 Gene
No Post-translational modifications
Other Protein References for NKIRAS1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for NKIRAS1
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-
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-
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Protein Products
-
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-
Abcam proteins for NKIRAS1
Assay Products
No data available for DME Specific Peptides for NKIRAS1 Gene
Domains & Families for NKIRAS1 Gene
Gene Families for NKIRAS1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for NKIRAS1 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for NKIRAS1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9NYS0UniProtKB/Swiss-Prot:
KBRS1_HUMAN :- In contrast to other members of the Ras family, the members of the KappaB-Ras subfamily do not contain the conserved Gly and Gln residues in positions 13 and 65, which are replaced by Leu residues, and are therefore similar to the constitutively active forms of oncogenic forms of Ras. This suggests that members of this family are clearly different from other small GTPases proteins.
- Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.
- Domain:
-
- In contrast to other members of the Ras family, the members of the KappaB-Ras subfamily do not contain the conserved Gly and Gln residues in positions 13 and 65, which are replaced by Leu residues, and are therefore similar to the constitutively active forms of oncogenic forms of Ras. This suggests that members of this family are clearly different from other small GTPases proteins.
- Family:
-
- Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.
Function for NKIRAS1 Gene
Molecular function for NKIRAS1 Gene
- UniProtKB/Swiss-Prot Function:
- Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003924 | GTPase activity | NAS | 10657303 |
| GO:0005525 | GTP binding | IEA | -- |
Phenotypes for NKIRAS1 Gene
- MGI mutant phenotypes for NKIRAS1:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for NKIRAS1:
Animal Models for NKIRAS1 Gene
- MGI Knock Outs for NKIRAS1:
-
- Nkiras1 tm1Brs
Animal Model Products
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-
-
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-
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Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for NKIRAS1
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miRNA for NKIRAS1 Gene
- miRTarBase miRNAs that target NKIRAS1
-
- hsa-mir-6505-3p (MIRT571853)
- hsa-mir-617 (MIRT571854)
- hsa-mir-4509 (MIRT571855)
- hsa-mir-4744 (MIRT571856)
- hsa-mir-519c-3p (MIRT571857)
- hsa-mir-519b-3p (MIRT571858)
- hsa-mir-519a-3p (MIRT571859)
- hsa-mir-4796-3p (MIRT571860)
- hsa-mir-3609 (MIRT571861)
- hsa-mir-548ah-5p (MIRT571862)
- hsa-mir-20a-5p (MIRT571863)
- hsa-mir-106b-5p (MIRT571864)
- hsa-mir-20b-5p (MIRT571865)
- hsa-mir-519d-3p (MIRT571866)
- hsa-mir-93-5p (MIRT571867)
- hsa-mir-526b-3p (MIRT571868)
- hsa-mir-17-5p (MIRT571869)
- hsa-mir-106a-5p (MIRT571870)
miRNA Products
- Search ViGene Biosciences for NKIRAS1
Inhibitory RNA Products
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Clone Products
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available NKIRAS1 gene related products
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- Applied Biological Materials Clones for NKIRAS1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
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Horizon Cell Lines for NKIRAS1
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No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for NKIRAS1 Gene
Localization for NKIRAS1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for NKIRAS1 Gene
- Cytoplasm.
| Compartment | Confidence |
|---|---|
| cytosol | 2 |
| plasma membrane | 1 |
| extracellular | 1 |
| mitochondrion | 1 |
| nucleus | 1 |
| lysosome | 1 |
- Microtubules (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005575 | cellular_component | ND | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0016020 | membrane | IEA | -- |
Pathways & Interactions for NKIRAS1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | NF-KappaB Family Pathway | ||
Pathways by source for NKIRAS1 Gene
1 Qiagen pathway for NKIRAS1 Gene
Interacting Proteins for NKIRAS1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007165 | signal transduction | IEA | -- |
| GO:0007249 | I-kappaB kinase/NF-kappaB signaling | NAS | 10657303 |
No data available for SIGNOR curated interactions for NKIRAS1 Gene
Drugs & Compounds for NKIRAS1 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Guanosine triphosphate | Experimental | Pharma | 0 |
Transcripts for NKIRAS1 Gene
mRNA/cDNA for NKIRAS1 Gene
- (4) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (93) Selected AceView cDNA sequences:
- (9) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for NKIRAS1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for NKIRAS1
- genomics-online: gRNA clones - Search results for available NKIRAS1 gene related products
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-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for NKIRAS1
- GenScript: Design CRISPR guide RNA sequences for NKIRAS1
miRNA Products
- Search ViGene Biosciences for NKIRAS1
Inhibitory RNA Products
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-
ViGene Biosciences ready-to-package AAV shRNAs for NKIRAS1 gene
Clone Products
- Sino Biological Human cDNA Clone for NKIRAS1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available NKIRAS1 gene related products
- orf clones - Search results for available NKIRAS1 gene related products
- Applied Biological Materials Clones for NKIRAS1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for NKIRAS1 Gene
This gene is overexpressed in Bone (18.2), Retina (17.7), and Frontal cortex (16.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for NKIRAS1 Gene
NURSA nuclear receptor signaling pathways regulating expression of NKIRAS1 Gene:
NKIRAS1SOURCE GeneReport for Unigene cluster for NKIRAS1 Gene:
Hs.173202mRNA Expression by UniProt/SwissProt for NKIRAS1 Gene:
Q9NYS0-KBRS1_HUMAN
Tissue specificity:
Widely expressed.
Evidence on tissue expression from TISSUES for NKIRAS1 Gene
- Nervous system(4.7)
- Lung(4.2)
Primer Products
-
OriGene qPCR primer pairs for NKIRAS1
-
OriGene qPCR primer pairs and template standards for NKIRAS1
- genomics-online: primer clones - Search results for available NKIRAS1 gene related products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for NKIRAS1 Gene
Orthologs for NKIRAS1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | NKIRAS1 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | NKIRAS1 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | NKIRAS1 34 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Nkiras1 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Nkiras1 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | NKIRAS1 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | NKIRAS1 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | NKIRAS1 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | NKIRAS1 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | nkiras1 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | nkiras1 33 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | kappaB-Ras 33 34 |
|
||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP011283 33 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | CELE_F52A8.6 33 |
|
||
| F52A8.6 34 |
|
OneToMany | |||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany |
- Species where no ortholog for NKIRAS1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for NKIRAS1 Gene
Variants for NKIRAS1 Gene
| SNP ID | Clin | Chr 03 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs35629664 | likely-benign, not specified | 23,917,934(-) | C/G/T | upstream_transcript_variant | |
| rs1000005534 | -- | 23,912,837(-) | C/T | intron_variant | |
| rs1000011300 | -- | 23,897,598(-) | C/T | intron_variant | |
| rs1000161174 | -- | 23,910,047(-) | C/T | intron_variant | |
| rs1000387932 | -- | 23,916,005(-) | T/C | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1005186 | CNV | gain | 25217958 |
Residual Variation Intolerance Score:
41.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.36;
7.93% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for NKIRAS1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- NKIRAS1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NKIRAS1 Gene
Disorders for NKIRAS1 Gene
Additional Disease Information for NKIRAS1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for NKIRAS1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NKIRAS1 Gene
Publications for NKIRAS1 Gene
- A subclass of Ras proteins that regulate the degradation of IkappaB. (PMID: 10657303) Fenwick C … Ghosh S (Science (New York, N.Y.) 2000) 2 3 4 22 58
- Genetic variation in the nuclear factor kappaB pathway in relation to susceptibility to rheumatoid arthritis. (PMID: 18434448) Dieguez-Gonzalez R … Gonzalez A (Annals of the rheumatic diseases 2009) 3 22 44 58
- Genetic and epigenetic changes of NKIRAS1 gene in human renal cell carcinomas. (PMID: 20693965) Gerashchenko GV … Kashuba VI (Experimental oncology 2010) 3 44 58
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
Products for NKIRAS1 Gene
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 83 available NKIRAS1 Antibodies ranked by validation data
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- Santa Cruz Biotechnology (SCBT) Antibodies for NKIRAS1
- Search Santa Cruz Biotechnology (SCBT) for NKIRAS1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for NKIRAS1
- Horizon Cell Lines for NKIRAS1
- genomics-online: cdna clones - Search results for available NKIRAS1 gene related products
- orf clones - Search results for available NKIRAS1 gene related products
- genomics-online: gRNA clones - Search results for available NKIRAS1 gene related products
- genomics-online: primer clones - Search results for available NKIRAS1 gene related products
- genomics-online: shRNA clones - Search results for available NKIRAS1 gene related products
Sources for NKIRAS1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew