NIT2 Gene
protein-coding GIFtS: 53
GCID: GC03P100053
|
|
nitrilase family, member 2
| |
Aliases
for NIT2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Nitrilase Family, Member 21 2 | | Nitrilase Homolog 22 3 | | Nit Protein 22 | | Omega-Amidase NIT22 | | EC 3.5.1.33 |
Export aliases for NIT2 gene to outside databasesPrevious GC identifers: GC03M096559 GC03P099332 GC03P101334 GC03P101374 GC03P101536 GC03P097421 |
Summaries
for NIT2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: NIT2_HUMAN, Q9NQR4Function: Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates byconverting alpha-ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate andoxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cellsin the G2 phase of the cell cycle
|
Genomic Views
for NIT2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_005612.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the NIT2 gene promoter:
AML1a Tal-1beta PPAR-gamma1 c-Rel POU2F1 POU2F1a PPAR-gamma2 ITF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for NIT2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NIT2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3q12.2 Ensembl cytogenetic band: 3q12.2 HGNC cytogenetic band: 3q12.3NIT2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03P100053: view genomic region
(about GC identifiers)
Start:
|
100,053,545 bp from pter |
End:
|
100,074,478 bp from pter |
Size:
|
20,934 bases |
Orientation:
|
plus strand |
|
Proteins
for NIT2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NIT2_HUMAN, Q9NQR4 (See
protein sequence)Recommended Name: Omega-amidase NIT2 Size: 276 amino acids; 30608 Da
Subunit: Homodimer
Subcellular location: Cytoplasm
Mass spectrometry: Mass=30585; Method=MALDI; Range=1-276; Source=PubMed:17488281;
Secondary accessions: B2R9A3 D3DN47 Q8WUF0Explore the universe of human proteins at neXtProt for NIT2: NX_Q9NQR4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NQR4
NIT2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_064587.1
ENSEMBL proteins: ENSP00000377696 ENSP00000419157 ENSP00000419239 ENSP00000419189
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
NIT2 for ontologies About GeneDecksing
NIT2 Antibody Products:
Assay Products for NIT2: |
Protein
Domains /
Families
for NIT2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NIT2 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9NQR4ProtoNet protein and cluster: Q9NQR4 1 Blocks protein family: IPB003010 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
UniProtKB/Swiss-Prot: NIT2_HUMAN, Q9NQR4Similarity: Belongs to the UPF0012 familySimilarity: Contains 1 CN hydrolase domain |
Function
for NIT2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: NIT2_HUMAN, Q9NQR4Function: Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates byconverting alpha-ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate andoxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cellsin the G2 phase of the cell cycleCatalytic activity: A monoamide of a dicarboxylic acid + H(2)O = a dicarboxylate + NH(3)Biophysicochemical properties: Kinetic parameters: KM=0.009 mM for alpha-ketoglutaramate (open-chain form); Vmax=5.9umol/min/mg enzyme with alpha-ketoglutaramate as substrate; Note=In solution, alpha-ketoglutaramate is in equilibriumwith a cyclic form (2-hydroxy-5-oxoproline), and at pH 8.0 or above, the rate of ring opening is no longer limitingfor the omega- amidase reaction;Enzyme Number (IUBMB): EC 3.5.1.31
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NIT2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NIT2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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| |  | GenScript: all cDNA clones in your preferred vector: NIT2 (NM_020202) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NIT2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NIT2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NIT2 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003674 | molecular_function |
ND | -- | | GO:0016810 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
-- | -- | | GO:0050152 | omega-amidase activity |
IEA | -- |
NIT2 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for NIT2:
Animal Models:
Mouse knock-out Nit2tm1Lex for NIT2
1 MGI phenotypic allele  for Nit2 (no phenotypes)
NIT2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for NIT2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Alanine, aspartate and glutamate metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Kegg Pathway (Kegg details for NIT2):
NIT2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NIT2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 20)
5/23 Interacting proteins for NIT2 (Q9NQR43 ENSP000003776964) via UniProtKB, MINT, STRING, and/or I2D (see all 23)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006807 | nitrogen compound metabolic process |
IEA | -- | | GO:0008150 | biological_process |
ND | -- |
NIT2 for ontologies About GeneDecksing
|
Drugs & Compounds
for NIT2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for NIT2
Search CenterWatch for drugs/clinical trials and news about NIT2
|
Transcripts
for NIT2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for NIT2 gene: NM_020202.4 Unigene Cluster for NIT2: Nitrilase family, member 2 Hs.439152 [show with all ESTs]Unigene Representative Sequence: AK2958357 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000394140(uc003dtv.3) ENST00000465368 ENST00000478856(uc011bha.1)
ENST00000480073 ENST00000460317 ENST00000497785 ENST00000472392
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NIT2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NIT2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: NIT2 (NM_020202) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NIT2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NIT2 |
Additional cDNA sequence: AF260334.1 AF284574.1 AJ293397.1 AK225979.1 AK294010.1 AK295835.1 AK313704.1 BC020620.1 BC107890.1 11 DOTS entries: DT.86840966 DT.95283275 DT.100746849 DT.75117739 DT.92434537 DT.100035823 DT.120874169 DT.97844800 DT.100812014 DT.95283295 DT.92434539 24/215 AceView cDNA sequences (see all 215): AI139570 BG612612 AI371139 BM888473 BG289591 BU188778 BU621063 BU618501 AI745093 BM846039 CA431363 N72246 BI520403 AI222479 AW016433 BM845906 BU626947 H49181 BF476154 CA424702 BM547991 AI343549 BG697846 AA825396
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for NIT2 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 |
|---|
|
| SP1: | | | | | - | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for NIT2
|
Expression
for NIT2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NIT2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CGGTTTGCAG
About this image
See NIT2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NIT2
SOURCE GeneReport for Unigene cluster: Hs.439152
UniProtKB/Swiss-Prot: NIT2_HUMAN, Q9NQR4Tissue specificity: Detected in fetal brain (at protein level). Ubiquitous. Detected in heart, brain, placenta, lung,liver, skeletal muscle, kidney, pancreas, prostate, spleen, thymus, prostate, testis, ovary, small intestine and colon
SABiosciences Expression via Pathway-Focused PCR Array including NIT2:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NIT2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NIT2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NIT2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NIT2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NIT2 |
Orthologs
for NIT2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for NIT2 gene from 10/37 species (see all 37) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Nit21 , 5 |
nitrilase family, member 21, 5 |
87.68(n)1
89.49(a)1 |
|
16 (34.22 cM)5
526331 NM_023175.11 NP_075664.11
571566715 |
chicken
(Gallus gallus) |
Aves |
NIT21 |
nitrilase family, member 2 |
76.85(n)
81.45(a) |
|
418386 XM_416604.3 XP_416604.3 |
lizard
(Anolis carolinensis) |
Reptilia |
NIT26 |
-- |
82(a) |
1 ↔ 1 |
3(174205448-174218478) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.47742 |
Xenopus laevis transcribed sequence with moderate similarity more |
77.39(n) |
|
CA971586.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.271782 |
Danio rerio clone RK139A2D11 Nit protein 2 (NIT2) mRNA, more |
76.19(n) |
|
AY398388.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG81323 |
nitrilase |
53(a) |
|
85D15 -- |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
NIT31 |
Nit3p |
53.63(n)
51.5(a) |
|
851065 NP_013455.1 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT5G120401 |
omega-amidase |
57.25(n)
59.85(a) |
|
831077 NM_121242.4 NP_196765.2 |
rice
(Oryza sativa) |
Liliopsida |
Os.191942 |
Oryza sativa (japonica cultivar-group) cDNA clone0 more |
73.62(n) |
|
AK059981.1 |
E. coli
(Escherichia coli) |
Gamma proteobacteria |
yafV6 |
predicted C-N hydrolase family amidase, NAD(P)-bin... |
21(a) |
possible ortholog |
Chromosome(239419-240189) |
ENSEMBL Gene Tree for NIT2 (if available)
TreeFam Gene Tree for NIT2 (if available) |
Paralogs
for NIT2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for NIT2 gene
1 SIMAP similar gene for NIT2 using alignment to 4 protein entries: NIT2_HUMAN (see all proteins):NIT1
NIT2 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for NIT2
PGOHUM00000244075
|
Genomic Variants
for NIT2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for NIT2 (100053545 - 100074478 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for NIT2: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NIT2 |
|
Disorders
/ Diseases
for NIT2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NIT2 for disorders About GeneDecksing
5  diseases for NIT2: About MalaCardsdown syndrome pneumonia tuberculosis prostatitis
mycobacterium tuberculosis
Export disorders for NIT2 gene to outside databases
|
Publications
for NIT2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NIT2 gene, integrated from 9 sources (see all 16):
(articles sorted by number of sources associating them with NIT2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Crystal structure of the worm NitFhit Rosetta stone protein reveals a Nit tetramer binding two Fhit dimers. (PubMed id 10959838)1, 2, 3 Pace H.C.... Brenner C. (2000)
- Growth inhibitory effect of the human NIT2 gene and its allelic imbalance in cancers. (PubMed id 17488281)1, 2, 9 Lin C.-H.... Chien C.-H. (2007)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Structural insights into the catalytic active site and activity of human Nit2/w-amidase: kinetic assay and molecular dynamics simulati on. (PubMed id 22674578)1 Chien C.H....Sheu S.Y. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Identification of the putative tumor suppressor Nit2 as omega- amidase, an enzyme metabolically linked to glutamine and asparagine transamination. (PubMed id 19595734)2 Krasnikov B.F.... Cooper A.J.L. (2009)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
- Transcriptome analysis of human gastric cancer. (PubMed id 16341674)1 Oh J.H....Kim N.S. (2005)
- Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)2 Rush J.... Comb M.J. (2005)
|
External Searches for NIT2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing NIT2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NIT2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NIT2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for NIT2 gene:
Search GeneIP for patents involving NIT2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for NIT2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for NIT2 | | OriGene shRNA RFP for NIT2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NIT2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NIT2 | | | OriGene Protein Over-expression Lysate for NIT2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for NIT2 | | OriGene 3'-UTR Clone for NIT2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NIT2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NIT2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for NIT2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for NIT2 | | OriGene Custom Protein Services for NIT2 | | | OriGene Custom Immunoassay Development | | |
| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NIT2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NIT2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NIT2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NIT2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NIT2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NIT2 |
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| | | | Search Tocris compounds for NIT2 |
| |  |  |  |  | | | | | | Recombinant Protein for NIT2 |
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 | | | NIT2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NIT2 |
|  |  |  | | | | ThermoFisher Antibodies for NIT2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NIT2 |
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