Aliases for NIT2 Gene
External Ids for NIT2 Gene
Previous GeneCards Identifiers for NIT2 Gene
GeneCards Summary for NIT2 Gene
NIT2 (Nitrilase Family Member 2) is a Protein Coding gene. Among its related pathways are Innate Immune System and Alanine, aspartate and glutamate metabolism. GO annotations related to this gene include hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds and omega-amidase activity.
UniProtKB/Swiss-Prot for NIT2 Gene
Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha-ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle.