NIT1 Gene
protein-coding GIFtS: 53
GCID: GC01P161087
|
|
nitrilase 1
| |
Aliases
for NIT1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Nitrilase 11 2 | | Nitrilase Homolog 12 | | EC 3.5.-.-3 |
Export aliases for NIT1 gene to outside databasesPrevious GC identifers: GC01P158799 GC01P156820 GC01P157865 GC01P158304 GC01P157900 GC01P159355 GC01P132445 |
Summaries
for NIT1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for NIT1:
This gene encodes a member of the nitrilase protein family with homology to bacterial and plant nitrilases, enzymesthat cleave nitriles and organic amides to the corresponding carboxylic acids plus ammonia. Multiple transcriptvariants encoding different isoforms have been found for this gene. (provided by RefSeq, Jun 2010)
UniProtKB/Swiss-Prot: NIT1_HUMAN, Q86X76Function: Plays a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNAdamage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effectis additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells. Hasapparently no omega-amidase activity such as NIT2 (By similarity)
|
Genomic Views
for NIT1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004487.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the NIT1 gene promoter:
HOXA9B HOXA9 p53 GATA-3 NRSF form 1 MIF-1 NRSF form 2 Egr-2 Meis-1a Meis-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for NIT1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NIT1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q21-q22 Ensembl cytogenetic band: 1q23.3 HGNC cytogenetic band: 1q21-q22NIT1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P161087: view genomic region
(about GC identifiers)
Start:
|
161,087,862 bp from pter |
End:
|
161,095,235 bp from pter |
Size:
|
7,374 bases |
Orientation:
|
plus strand |
|
Proteins
for NIT1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NIT1_HUMAN, Q86X76 (See
protein sequence)Recommended Name: Nitrilase homolog 1 Size: 327 amino acids; 35896 Da
Subcellular location: Cytoplasm. Mitochondrion (By similarity)
Miscellaneous: According to Rosetta Stone theory, the existence of a fusion protein in one genome predicts that theseparate polypeptides expressed in other organisms function in the same cellular or biochemical pathway. In Drosophilamelanogaster and Caenorhabditis elegans, NitFhit is a fusion protein composed of a C-terminal Fhit domain and a domainrelated to plant and bacterial nitrilase
Sequence caution: Sequence=AAH46149.1; Type=Miscellaneous discrepancy; Note=Chimeric cDNA. Its C-terminal exon isderived from the last exon of the DEDD gene;
Secondary accessions: B1AQP3 D3DVF4 O76091Alternative splicing: 4 isoforms: Q86X76-1 Q86X76-2 Q86X76-3 Q86X76-4 (Major isoform)Explore the universe of human proteins at neXtProt for NIT1: NX_Q86X76
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q86X76
NIT1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001172021.1 NP_001172022.1 NP_001172023.1 NP_005591.1
ENSEMBL proteins: ENSP00000356988 ENSP00000356987 ENSP00000356986 ENSP00000376028
Human Recombinant Protein Products for NIT1:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005739 | mitochondrion |
IEA | -- |
NIT1 for ontologies About GeneDecksing
NIT1 Antibody Products:
Assay Products for NIT1: |
Protein
Domains /
Families
for NIT1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NIT1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q86X76ProtoNet protein and cluster: Q86X76 2 Blocks protein families: IPB001110 Protein of unknown function UPF0012 IPB003010 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
UniProtKB/Swiss-Prot: NIT1_HUMAN, Q86X76Similarity: Belongs to the UPF0012 familySimilarity: Contains 1 CN hydrolase domain |
Function
for NIT1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: NIT1_HUMAN, Q86X76Function: Plays a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNAdamage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effectis additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells. Hasapparently no omega-amidase activity such as NIT2 (By similarity) Enzyme Number (IUBMB): EC 3.5.-.-1
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000257 | nitrilase activity |
TAS | 9671749 | | GO:0016810 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
-- | -- |
NIT1 for ontologies About GeneDecksing
Phenotypes:
6 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Nit1):
NIT1 for phenotypes About GeneDecksing
Animal Models:
Mouse knock-outs for NIT1: Nit1tm1Lex Nit1tm1.1Hbn
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NIT1 (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NIT1
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 4): NIT1 (NM_005600) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NIT1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NIT1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NIT1 |
|
Pathways & Interactions
for NIT1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NIT1
STRING Interaction
Network Preview (showing 4 interactants - click image to see more details)
5/10 Interacting proteins for NIT1 (Q86X762, 3 ENSP000003569884) via UniProtKB, MINT, STRING, and/or I2D (see all 10)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006807 | nitrogen compound metabolic process |
IEA | -- | | GO:0008150 | biological_process |
ND | -- |
NIT1 for ontologies About GeneDecksing
|
Drugs & Compounds
for NIT1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for NIT1
Search CenterWatch for drugs/clinical trials and news about NIT1
|
Transcripts
for NIT1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for NIT1 gene (4 alternative transcripts): NM_001185092.1 NM_001185093.1 NM_001185094.1 NM_005600.2 Unigene Cluster for NIT1: Nitrilase 1 Hs.146406 [show with all ESTs]Unigene Representative Sequence: NM_00118509216 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000496768 ENST00000368009 ENST00000479266 ENST00000477684 ENST00000486962
ENST00000492411 ENST00000368008(uc001fxw.3) ENST00000473918 ENST00000478277
ENST00000496861 ENST00000491497 ENST00000485594 ENST00000461376 ENST00000479728
ENST00000368007(uc010pka.2) ENST00000392190(uc001fxv.2 uc001fxy.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NIT1 (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NIT1
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 4): NIT1 (NM_005600) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NIT1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NIT1 |
Additional cDNA sequence: AF069987.1 AK296606.1 AK313323.1 BC046149.1 CR541814.1 CR541846.1 24/27 DOTS entries (see all 27): DT.100878742 DT.95171244 DT.100878736 DT.95171160 DT.70102677 DT.100878738 DT.100839476 DT.121398618 DT.449341 DT.100878721 DT.121398561 DT.121398575 DT.92449686 DT.99980132 DT.100878720 DT.100038735 DT.121398636 DT.97808063 DT.100878722 DT.100878728 DT.100878729 DT.100878735 DT.121398563 DT.92449679 24/305 AceView cDNA sequences (see all 305): AI126753 CR609891 CR593362 AA913796 BM723823 BI711712 AI000825 AA931258 BU677808 BM804704 CR541846 BQ582098 BI496756 AA346667 AA887544 BX509430 BM451299 Z45348 AA586578 AA352746 BQ581760 BM975958 BM662704 AA766114
GeneLoc Exon Structure
5/10 Alternative Splicing Database (ASD) splice patterns (SP) for NIT1 (see all 10) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | · | 6d | ^ | 7a | · | 7b | ^ | 8a | · | 8b |
|---|
|
| SP1: | | | | | - | | - | | - | | - | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | - | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | - | | - | | - | | - | | - | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for NIT1
|
Expression
for NIT1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NIT1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAAACTGAAG
About this image
See NIT1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NIT1
SOURCE GeneReport for Unigene cluster: Hs.146406
UniProtKB/Swiss-Prot: NIT1_HUMAN, Q86X76Tissue specificity: Detected in heart, brain, placenta, liver, skeletal muscle, kidney and pancreas
SABiosciences Custom PCR Arrays for NIT1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NIT1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NIT1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NIT1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NIT1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NIT1 |
Orthologs
for NIT1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for NIT1 gene from 9/29 species (see all 29) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
LOC4295661 |
nitrilase homolog 1-like |
66.02(n)
65.91(a) |
|
429566 XM_003642703.1 XP_003642751.1 |
African clawed frog
(Xenopus laevis) |
Amphibia |
Nit12 |
Nit protein 1 |
75.72(n) |
|
AF284575.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.160222 |
Transcribed sequence with weak similarity to protein more |
71.08(n) |
|
BG737861.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
NitFhit3 |
nitrilase |
48(a) |
|
61B2 -- |
worm
(Caenorhabditis elegans) |
Secernentea |
nft-13 |
-- |
50(a) |
|
III(11995535-12000978) -- |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
NIT2(YJL126W)4
NIT21 |
Nit protein, one of two proteins in S. cerevisiae with more4
Nit2p1 |
46.55(n)1
41.09(a)1 |
|
10(184501-185424)4
8533161, 4 NP_012409.11, 4 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT4G087901 |
Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase more |
52.75(n)
48.28(a) |
|
826449 NM_116949.3 NP_567340.1 |
rice
(Oryza sativa) |
Liliopsida |
Os12g05025001 |
hypothetical protein |
51.72(n)
47.69(a) |
|
4352282 NM_001073362.2 NP_001066830.1 |
E. coli
(Escherichia coli) |
Gamma proteobacteria |
yafV6 |
predicted C-N hydrolase family amidase, NAD(P)-bin... |
22(a) |
possible ortholog |
Chromosome(239419-240189) |
ENSEMBL Gene Tree for NIT1 (if available)
TreeFam Gene Tree for NIT1 (if available) |
Paralogs
for NIT1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for NIT1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for NIT1 (161087862 - 161095235 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for NIT1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NIT1 |
|
Disorders
/ Diseases
for NIT1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NIT1 for disorders About GeneDecksing
OMIM gene information: 604618
OMIM disorders: --
6  diseases for NIT1: About MalaCardsintrahepatic cholangiocarcinoma insulinoma cholangiocarcinoma pneumonia
tuberculosis mycobacterium tuberculosis
2 diseases from the University of Copenhagen DISEASES database for NIT1:Diabetes mellitus Insulinoma 1 Novoseek disease relationship for NIT1 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tumors |
0 |
3 |
16864578 (1), 19395373 (1) |
Human Genome Epidemiology (HuGE) Navigator: NIT1 (1 document)
Export disorders for NIT1 gene to outside databases
|
Publications
for NIT1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NIT1 gene, integrated from 9 sources (see all 20):
(articles sorted by number of sources associating them with NIT1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Nitrilase and Fhit homologs are encoded as fusion proteins in Drosophila melanogaster and Caenorhabditis elegans. (PubMed id 9671749)1, 2, 3, 9 Pekarsky Y.... Croce C.M. (1998)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Biological functions of mammalian Nit1, the counterpart of the invertebrate NitFhit Rosetta stone protein, a possible tumor suppressor. (PubMed id 16864578)1, 9 Semba S....Huebner K. (2006)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1 Hendrickson S.L....O'Brien S.J. (2010)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)
- A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569)1 Lim J.... Zoghbi H.Y. (2006)
|
External Searches for NIT1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing NIT1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NIT1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NIT1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for NIT1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for NIT1 gene:
Search GeneIP for patents involving NIT1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for NIT1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
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| | |  | OriGene Antibodies for NIT1 | | OriGene shRNA RFP for NIT1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NIT1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NIT1 | | | OriGene Protein Over-expression Lysate for NIT1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for NIT1 | | OriGene 3'-UTR Clone for NIT1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NIT1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NIT1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for NIT1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for NIT1 | | OriGene Custom Protein Services for NIT1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NIT1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NIT1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NIT1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NIT1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NIT1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NIT1 |
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 | | | NIT1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NIT1 |
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| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NIT1 |
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