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Aliases for NIPSNAP3A Gene

Aliases for NIPSNAP3A Gene

  • Nipsnap Homolog 3A (C. Elegans) 2 3
  • TASSC 3 4 6
  • Target For Salmonella Secreted Protein C 3 4
  • Protein NipSnap Homolog 4 3 4
  • NIPSNAP4 3 4
  • Protein NipSnap Homolog 3A 3
  • NipSnap3A 4
  • HSPC299 3

External Ids for NIPSNAP3A Gene

Previous GeneCards Identifiers for NIPSNAP3A Gene

  • GC09P102889
  • GC09P104589
  • GC09P106549
  • GC09P107509
  • GC09P077113

Summaries for NIPSNAP3A Gene

Entrez Gene Summary for NIPSNAP3A Gene

  • NIPSNAP3A belongs to a family of proteins with putative roles in vesicular transport (Buechler et al., 2004 [PubMed 15177564]).[supplied by OMIM, Mar 2008]

GeneCards Summary for NIPSNAP3A Gene

NIPSNAP3A (Nipsnap Homolog 3A (C. Elegans)) is a Protein Coding gene. An important paralog of this gene is NIPSNAP3B.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NIPSNAP3A Gene

Genomics for NIPSNAP3A Gene

Regulatory Elements for NIPSNAP3A Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for NIPSNAP3A Gene

104,747,688 bp from pter
104,760,122 bp from pter
12,435 bases
Plus strand

Genomic View for NIPSNAP3A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for NIPSNAP3A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NIPSNAP3A Gene

Proteins for NIPSNAP3A Gene

  • Protein details for NIPSNAP3A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein NipSnap homolog 3A
    Protein Accession:
    Secondary Accessions:
    • A6NM55
    • Q5VX32
    • Q9BRV7
    • Q9H843
    • Q9P083

    Protein attributes for NIPSNAP3A Gene

    247 amino acids
    Molecular mass:
    28467 Da
    Quaternary structure:
    • Interacts with the Salmonella typhimurium virulence protein spiC.
    • Sequence=AAF28977.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for NIPSNAP3A Gene

Proteomics data for NIPSNAP3A Gene at MOPED

Post-translational modifications for NIPSNAP3A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for NIPSNAP3A Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for NIPSNAP3A Gene

Domains for NIPSNAP3A Gene

Protein Domains for NIPSNAP3A Gene


Suggested Antigen Peptide Sequences for NIPSNAP3A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the NipSnap family.
  • Belongs to the NipSnap family.
genes like me logo Genes that share domains with NIPSNAP3A: view

No data available for Gene Families for NIPSNAP3A Gene

Function for NIPSNAP3A Gene

Gene Ontology (GO) - Molecular Function for NIPSNAP3A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 21988832
genes like me logo Genes that share ontologies with NIPSNAP3A: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for NIPSNAP3A

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NIPSNAP3A Gene

Localization for NIPSNAP3A Gene

Subcellular locations from UniProtKB/Swiss-Prot for NIPSNAP3A Gene

Cytoplasm, cytosol. Note=May be part of some vesicular structure distinct from lysosomal vesicles.

Subcellular locations from

Jensen Localization Image for NIPSNAP3A Gene COMPARTMENTS Subcellular localization image for NIPSNAP3A gene
Compartment Confidence
cytosol 5
mitochondrion 3
vacuole 1

Gene Ontology (GO) - Cellular Components for NIPSNAP3A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA 21630459
GO:0005737 cytoplasm --
GO:0005829 cytosol IEA --
genes like me logo Genes that share ontologies with NIPSNAP3A: view

Pathways for NIPSNAP3A Gene

SuperPathways for NIPSNAP3A Gene

No Data Available

Gene Ontology (GO) - Biological Process for NIPSNAP3A Gene


No data available for Pathways by source for NIPSNAP3A Gene

Transcripts for NIPSNAP3A Gene


Unigene Clusters for NIPSNAP3A Gene

Nipsnap homolog 3A (C. elegans):
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for NIPSNAP3A

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for NIPSNAP3A Gene

No ASD Table

Relevant External Links for NIPSNAP3A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for NIPSNAP3A Gene

mRNA expression in normal human tissues for NIPSNAP3A Gene

Protein differential expression in normal tissues for NIPSNAP3A Gene

This gene is overexpressed in Fetal testis (6.2).

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for NIPSNAP3A Gene

SOURCE GeneReport for Unigene cluster for NIPSNAP3A Gene Hs.530275

mRNA Expression by UniProt/SwissProt for NIPSNAP3A Gene

Tissue specificity: Ubiquitous. Highly expressed in liver, kidney and muscle. Expressed at intermediate level in brain, heart, colon, thymus, kidney, small intestine, placenta, lung, leukocytes and spleen.
genes like me logo Genes that share expressions with NIPSNAP3A: view

Expression partners for NIPSNAP3A Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for NIPSNAP3A Gene

Orthologs for NIPSNAP3A Gene

This gene was present in the common ancestor of chordates.

Orthologs for NIPSNAP3A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia NIPSNAP3A 35
  • 91.5 (n)
  • 89.88 (a)
  • 90 (a)
(Canis familiaris)
Mammalia LOC474791 35
  • 90.96 (n)
  • 90.28 (a)
  • 90 (a)
(Mus musculus)
Mammalia Nipsnap3b 35
  • 83.94 (n)
  • 83.4 (a)
Nipsnap3a 16
Nipsnap3a 36
  • 76 (a)
(Pan troglodytes)
Mammalia NIPSNAP3A 35
  • 99.87 (n)
  • 100 (a)
  • 100 (a)
(Rattus norvegicus)
Mammalia Nipsnap3b 35
  • 83.54 (n)
  • 82.19 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 66 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 76 (a)
(Gallus gallus)
  • 72.98 (n)
  • 70.93 (a)
-- 36
  • 66 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 58 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia nipsnap3a 35
  • 65.56 (n)
  • 62.5 (a)
(Danio rerio)
Actinopterygii nipsnap3 35
  • 62.16 (n)
  • 61.26 (a)
nipsnap3 36
  • 52 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.8944 36
  • 36 (a)
Species with no ortholog for NIPSNAP3A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for NIPSNAP3A Gene

Gene Tree for NIPSNAP3A (if available)
Gene Tree for NIPSNAP3A (if available)

Paralogs for NIPSNAP3A Gene

Paralogs for NIPSNAP3A Gene

(1) SIMAP similar genes for NIPSNAP3A Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with NIPSNAP3A: view

Variants for NIPSNAP3A Gene

Sequence variations from dbSNP and Humsavar for NIPSNAP3A Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs1046115 -- 104,759,442(+) AGGTG(G/T)TAAGT utr-variant-3-prime
rs1061582 -- 104,748,932(+) TAAAA(A/G)TCATC intron-variant
rs1858555 -- 104,750,150(+) CGTGC(A/G)TAGTT intron-variant
rs2274870 - 104,752,933(+) AGTTC(A/G)GAAAG missense, reference
rs2297397 -- 104,759,215(+) AATGT(A/G)TTTCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for NIPSNAP3A Gene

Variant ID Type Subtype PubMed ID
nsv893672 CNV Gain+Loss 21882294
nsv521783 CNV Loss 19592680

Relevant External Links for NIPSNAP3A Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NIPSNAP3A Gene

Disorders for NIPSNAP3A Gene

(1) University of Copenhagen DISEASES for NIPSNAP3A Gene

Relevant External Links for NIPSNAP3A

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with NIPSNAP3A: view

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , Novoseek inferred disease relationships and Genatlas for NIPSNAP3A Gene

Publications for NIPSNAP3A Gene

  1. Expression pattern and raft association of NIPSNAP3 and NIPSNAP4, highly homologous proteins encoded by genes in close proximity to the ATP-binding cassette transporter A1. (PMID: 15177564) Buechler C. … Schmitz G. (Genomics 2004) 3 23
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson S.L. … O'Brien S.J. (PLoS ONE 2010) 3 48

Products for NIPSNAP3A Gene

Sources for NIPSNAP3A Gene

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