Aliases for NIPAL4 Gene
External Ids for NIPAL4 Gene
This gene likely encodes a membrane receptor. Mutations in this gene have been associated with autosomal recessive congenital ichthyosis. [provided by RefSeq, Feb 2010]
GeneCards Summary for NIPAL4 Gene
NIPAL4 (NIPA-Like Domain Containing 4) is a Protein Coding gene. Diseases associated with NIPAL4 include ichthyosis, congenital, autosomal recessive 6 and congenital ichthyosiform erythroderma. GO annotations related to this gene include magnesium ion transmembrane transporter activity. An important paralog of this gene is NIPAL3.
UniProtKB/Swiss-Prot for NIPAL4 Gene
Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Ba(2+), Mn(2+), Sr(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity). May be a receptor for ligands (trioxilins A3 and B3) from the hepoxilin pathway.