Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



NIPAL2 Gene

protein-coding   GIFtS: 42
GCID: GC08M099202

NIPA-Like Domain Containing 2


(Previous symbol: NPAL2)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
NIPA-Like Domain Containing 21 2
NPAL21 2 3
NIPA-Like Protein 22

External Ids:    HGNC: 258541   Entrez Gene: 798152   Ensembl: ENSG000001043617   UniProtKB: Q9H8413   

Export aliases for NIPAL2 gene to outside databases

Previous GC identifers: GC08M099278 GC08M094407


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for NIPAL2 Gene:
NIPAL2 (NIPA-like domain containing 2) is a protein-coding gene. Diseases associated with NIPAL2 include autosomal recessive congenital ichthyosis, and choroiditis. GO annotations related to this gene include magnesium ion transmembrane transporter activity. An important paralog of this gene is NIPA1.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000008.11  NT_008046.17  NC_018919.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the NIPAL2 gene promoter:
         USF1   AML1a   Pax-2   Pax-2a   POU6F1 (c2)   GATA-1   POU2F1   POU2F1a   USF-1   c-Myb   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNIPAL2 promoter sequence
   Search Chromatin IP Primers for NIPAL2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NIPAL2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q22.2   Ensembl cytogenetic band:  8q22.2   HGNC cytogenetic band: 8q22.2

NIPAL2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NIPAL2 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M099202:  view genomic region     (about GC identifiers)

Start:
99,202,061 bp from pter      End:
99,306,621 bp from pter
Size:
104,561 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: NPAL2_HUMAN, Q9H841 (See protein sequence)
Recommended Name: NIPA-like protein 2  
Size: 368 amino acids; 40785 Da

Explore the universe of human proteins at neXtProt for NIPAL2: NX_Q9H841

Explore proteomics data for NIPAL2 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn33, Asn274

  • See NIPAL2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_079035.1  
    ENSEMBL proteins: 
     ENSP00000407087   ENSP00000339256  

    NIPAL2 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for NIPAL2
    GenScript Custom Purified and Recombinant Proteins Services for NIPAL2
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for NIPAL2

    NIPAL2 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for NIPAL2
    Novus Biologicals NIPAL2 Antibody
    Search for Antibodies for NIPAL2 at Abcam
    Cloud-Clone Corp. Antibodies for NIPAL2
    ThermoFisher Antibodies for NIPAL2
    LSBio Antibodies in human, mouse, rat for NIPAL2

    NIPAL2 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for NIPAL2
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for NIPAL2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for NIPAL2
    Cloud-Clone Corp. CLIAs for NIPAL2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    1 InterPro protein domain:
     IPR008521 Mg_trans_NIPA

    Graphical View of Domain Structure for InterPro Entry Q9H841

    ProtoNet protein and cluster: Q9H841

    UniProtKB/Swiss-Prot: NPAL2_HUMAN, Q9H841
    Similarity: Belongs to the NIPA family


    NIPAL2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015095magnesium ion transmembrane transporter activity IEA--
         
    NIPAL2 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for NIPAL2:
     Increased G1 DNA content 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NIPAL2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for NIPAL2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NIPAL2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NIPAL2

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat NIPAL2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NIPAL2 (see all 13):
    hsa-miR-607 hsa-miR-621 hsa-miR-3684 hsa-miR-1305 hsa-miR-151-3p hsa-miR-587 hsa-miR-942 hsa-miR-19b
    SwitchGear 3'UTR luciferase reporter plasmidNIPAL2 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for NIPAL2
    Predesigned siRNA for gene silencing in human, mouse, rat NIPAL2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for NIPAL2

    Clone
    Products:
         
    OriGene clones in human, mouse for NIPAL2 (see all 6)
    OriGene ORF clones in mouse, rat for NIPAL2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NIPAL2 (NM_024759)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NIPAL2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NIPAL2

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for NIPAL2
    Browse ESI BIO Cell Lines and PureStem Progenitors for NIPAL2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NIPAL2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    NPAL2_HUMAN, Q9H841: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016020membrane ----
    GO:0016021integral component of membrane IEA--

    NIPAL2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NIPAL2
    Interactions:

        Search GeneGlobe Interaction Network for NIPAL2

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015693magnesium ion transport ----

    NIPAL2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NIPAL2 (NPAL2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for NIPAL2 gene: 
    NM_024759.1  

    Unigene Cluster for NIPAL2:

    NIPA-like domain containing 2
    Hs.309489  [show with all ESTs]
    Unigene Representative Sequence: AK025015
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000430223(uc011lgw.1) ENST00000341166(uc003yil.1 uc003yim.1)
    ENST00000520545 ENST00000521820 ENST00000522188 ENST00000520735 ENST00000521949
    ENST00000519324
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat NIPAL2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NIPAL2 (see all 13):
    hsa-miR-607 hsa-miR-621 hsa-miR-3684 hsa-miR-1305 hsa-miR-151-3p hsa-miR-587 hsa-miR-942 hsa-miR-19b
    SwitchGear 3'UTR luciferase reporter plasmidNIPAL2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for NIPAL2
    Predesigned siRNA for gene silencing in human, mouse, rat NIPAL2
    Clone
    Products:
         
    OriGene clones in human, mouse for NIPAL2 (see all 6)
    OriGene ORF clones in mouse, rat for NIPAL2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NIPAL2 (NM_024759)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NIPAL2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NIPAL2
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for NIPAL2
    OriGene qSTAR qPCR primer pairs in human, mouse for NIPAL2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NIPAL2
      QuantiTect SYBR Green Assays in human, mouse, rat NIPAL2
      QuantiFast Probe-based Assays in human, mouse, rat NIPAL2

    Additional mRNA sequence: 

    AK024017.1 AK025015.1 AK302414.1 BC132687.1 BC144055.1 

    6 DOTS entries:

    DT.310634  DT.102826671  DT.95151717  DT.91661773  DT.75136718  DT.97808849 

    Selected AceView cDNA sequences (see all 78):

    AL704225 AI697643 CD723228 CA427789 BE217842 AI302784 AI753381 AI753382 
    CA426282 AA705656 AI247523 BF933249 AK024017 AI458808 BU677761 CB151667 
    AA257079 AA424857 NM_024759 BX101014 AI762161 BP346328 AL710215 W24794 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    NIPAL2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAGTAGATTA
    NIPAL2 Expression
    About this image


    NIPAL2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Epithelial Cells
             Mature Choroid Plexus Cells Choroid Plexus
     
     Brain (Nervous System)
             Mature Choroid Plexus Cells Choroid Plexus
    NIPAL2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NIPAL2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.309489
        Custom PCR Arrays for NIPAL2
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for NIPAL2
    OriGene qSTAR qPCR primer pairs in human, mouse for NIPAL2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NIPAL2
    QuantiTect SYBR Green Assays in human, mouse, rat NIPAL2
    QuantiFast Probe-based Assays in human, mouse, rat NIPAL2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NIPAL2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for NIPAL2 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nipal21 , 5 NIPA-like domain containing 21, 5 84.31(n)1
    83.57(a)1
      15 (14.34 cM)5
    2234731  NM_145469.51  NP_663444.21 
     345727995 
    chicken
    (Gallus gallus)
    Aves NIPAL21 NIPA-like domain containing 2 70.48(n)
    62.6(a)
      771428  XM_003640845.2  XP_003640893.2 
    lizard
    (Anolis carolinensis)
    Reptilia NIPAL26
    NIPA-like domain containing 2
    54(a)
    1 ↔ 1
    4(20736752-20782235)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC537052 hypothetical protein MGC53705 71.05(n)    BC043862.1 
    zebrafish
    (Danio rerio)
    Actinopterygii NIPAL2 (2 of 2)6
    NIPAL2 (1 of 2)6
    NIPA-like domain containing 2
    57(a)
    49(a)
    1 ↔ many
    1 ↔ many
    16(57957253-57958017) ENSDARG00000087903
    16(58140440-58142865) ENSDARG00000076253
    fruit fly
    (Drosophila melanogaster)
    Insecta spict6
    spichthyin
    23(a)
    1 → many
    2L(12704725-12706683)
    worm
    (Caenorhabditis elegans)
    Secernentea nipa-16
    Protein NIPA-1, isoform b (nipa-1) mRNA, complete ...
    23(a)
    1 → many
    III(3112487-3127117) WBGene00021820


    ENSEMBL Gene Tree for NIPAL2 (if available)
    TreeFam Gene Tree for NIPAL2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for NIPAL2 gene
    NIPA12  NIPAL32  NIPAL12  NIPAL42  NIPA22  
    5 SIMAP similar genes for NIPAL2 using alignment to 1 protein entry:     NPAL2_HUMAN:
    NPAL2    NIPAL3    NIPAL4    NIPA2    NIPAL1

    NIPAL2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for NIPAL2 (see all 1999)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs3697078001,2
    C--94474611(+) TATTC-/CTTT  
            
    TTTTT
    1 -- int11Minor allele frequency- CTTT:0.00NA 2
    rs625222441,2
    C,F--99203938(+) GCTACT/CTCTTT 1 -- ds50019Minor allele frequency- C:0.48WA NA CSA EA 370
    rs1849173311,2
    C--99204159(+) CACAAC/TTCTCC 1 -- ds50010--------
    rs726806531,2
    --99204460(+) ATTTAC/TGTGTC 1 -- ut310--------
    rs1881192101,2
    --99204513(+) TTTAGC/TACATG 1 -- ut310--------
    rs1406619371,2
    C--99204569(+) TTACAC/TGTAAA 1 -- ut310--------
    rs47343911,2
    C,F,A,H--99204718(+) TCTAAC/TTTAGT 1 -- ut3121Minor allele frequency- T:0.49NS EA NA WA CSA 2342
    rs47343921,2
    C,F,A,H--99204723(+) CTTAGT/GACTTG 1 -- ut3112Minor allele frequency- G:0.41NS EA NA WA 780
    rs47355381,2
    C,F,H--99204766(+) AGGTGT/ACTTAG 1 -- ut31 ese315Minor allele frequency- A:0.41NA NS EA WA 908
    rs173583391,2
    C,F,H--99205046(+) CTTAGG/AAAGTC 1 -- ut318Minor allele frequency- A:0.01NA NS EA 678

    HapMap Linkage Disequilibrium report for NIPAL2 (99202061 - 99306621 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for NIPAL2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2656906CNV Deletion23128226
    esv2669746CNV Deletion23128226
    esv1594433CNV Deletion17803354
    esv2737348CNV Deletion23290073
    esv2659931CNV Deletion23128226
    nsv831406CNV Loss17160897
    nsv6326CNV Loss18451855
    nsv397166CNV Loss16902084
    nsv891216CNV Loss21882294
    nsv831405CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NIPAL2
    DNA2.0 Custom Variant and Variant Library Synthesis for NIPAL2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    2 diseases for NIPAL2:    
    About MalaCards
    autosomal recessive congenital ichthyosis    choroiditis


    NIPAL2 for disorders           About GeneDecksing


    Export disorders for NIPAL2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for NIPAL2 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with NIPAL2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2, 3 Ota T.... Sugano S. (Nat. Genet. 2004)
    2. Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans. (PubMed id 23400010)1 Del-Aguila J.L....Boerwinkle E. (Pharmacogenomics J. 2013)
    3. Mutations in ichthyin a new gene on chromosome 5q33 in a new form of autosomal recessive congenital ichthyosis. (PubMed id 15317751)1 Lefevre C.... Fischer J. (Hum. Mol. Genet. 2004)
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 79815 HGNC: 25854 AceView: FLJ13955 Ensembl:ENSG00000104361 euGenes: HUgn79815
    ECgene: NIPAL2 H-InvDB: NIPAL2

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for NIPAL2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for NIPAL2 gene:
    Search GeneIP for patents involving NIPAL2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for NIPAL2  
     OriGene qPCR primer pairs and template standards for NIPAL2   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for NIPAL2  
     OriGene qSTAR qPCR primer pairs in human, mouse for NIPAL2   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for NIPAL2   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for NIPAL2   OriGene Custom Protein Services for NIPAL2  

     
     
     Block miRNA regulation of human, mouse, rat NIPAL2 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing NIPAL2
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NIPAL2 Predesigned siRNA for gene silencing in human, mouse, rat NIPAL2
     QuantiFast Probe-based Assays in human, mouse, rat NIPAL2 QuantiTect SYBR Green Assays in human, mouse, rat NIPAL2
     Custom PCR Arrays for NIPAL2 Search Chromatin IP Primers for NIPAL2
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NIPAL2  Search GeneGlobe Interaction Network for NIPAL2
     Regulatory tfbs in NIPAL2 promoter
     GenScript Custom Purified and Recombinant Proteins Services for NIPAL2 GenScript cDNA clones with any tag delivered in your preferred vector for NIPAL2
     GenScript Custom Assay Services for NIPAL2 GenScript Custom overexpressing Cell Line Services for NIPAL2
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for NIPAL2 (NPAL2)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     NIPAL2 antibodies
     Search for Antibodies for NIPAL2 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for NIPAL2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for NIPAL2
     Antibodies for NIPAL2
     ELISAs for NIPAL2
     CLIAs for NIPAL2



     Browse ESI BIO Cell Lines and PureStem Progenitors for NIPAL2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NIPAL2
     SwitchGear 3'UTR luciferase reporter plasmids for NIPAL2
     SwitchGear Promoter luciferase reporter plasmids for NIPAL2
     ThermoFisher Antibodies for NIPAL2
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NIPAL2
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NIPAL2
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for NIPAL2
     LSBio Antibodies in human, mouse, rat for NIPAL2
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      NIPAL2 gene at Home site.
    Version: 3.12.166 28 Aug 2014
    hostname: 356980-web2.xennexinc.com index build: 126 solr: 1.4