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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NIPA2 Gene

protein-coding   GIFtS: 50
GCID: GC15M023004

Non Imprinted In Prader-Willi/Angelman Syndrome 2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Non Imprinted In Prader-Willi/Angelman Syndrome 21 2
Non-Imprinted In Prader-Willi/Angelman Syndrome Region Protein 22 3
Magnesium Transporter NIPA22

External Ids:    HGNC: 170441   Entrez Gene: 816142   Ensembl: ENSG000001401577   OMIM: 6081465   UniProtKB: Q8N8Q93   

Export aliases for NIPA2 gene to outside databases

Previous GC identifers: GC15M020423 GC15M020553 GC15M020556 GC15M001317


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NIPA2 Gene:
This gene encodes a possible magnesium transporter. This gene is located adjacent to the imprinted domain in the
Prader-Willi syndrome deletion region of chromosome 15. Alternate splicing results in multiple transcript
variants. Pseudogenes of this gene are found on chromosomes 3, 7 and 21.(provided by RefSeq, May 2010)

GeneCards Summary for NIPA2 Gene: 
NIPA2 (non imprinted in Prader-Willi/Angelman syndrome 2) is a protein-coding gene. Diseases associated with NIPA2 include microdeletion 15q11.2, and prader-willi syndrome. GO annotations related to this gene include magnesium ion transmembrane transporter activity. An important paralog of this gene is NIPA1.

UniProtKB/Swiss-Prot: NIPA2_HUMAN, Q8N8Q9
Function: Acts as a selective Mg(2+) transporter (By similarity)

Gene Wiki entry for NIPA2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000015.9  NT_078094.2  NC_018926.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NIPA2 gene promoter:
         Olf-1   Pax-2   Pax-2a   NF-AT   NF-AT4   NF-AT2   Pax-2b   NF-AT3   Msx-1   NF-AT1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNIPA2 promoter sequence
   Search SABiosciences Chromatin IP Primers for NIPA2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NIPA2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q11.2   Ensembl cytogenetic band:  15q11.2   HGNC cytogenetic band: 15q11.2

NIPA2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NIPA2 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M023004:  view genomic region     (about GC identifiers)

Start:
23,004,684 bp from pter      End:
23,034,427 bp from pter
Size:
29,744 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NIPA2_HUMAN, Q8N8Q9 (See protein sequence)
Recommended Name: Magnesium transporter NIPA2  
Size: 360 amino acids; 39185 Da
Subcellular location: Cell membrane; Multi-pass membrane protein (Potential). Early endosome (By similarity).
Note=Recruited to the cell membrane in response to low extracellular magnesium (By similarity)
Secondary accessions: F8W7Y8 Q96F03 Q9BVS2
Alternative splicing: 2 isoforms:  Q8N8Q9-1   Q8N8Q9-2   (Not experimental evidence available)

Explore the universe of human proteins at neXtProt for NIPA2: NX_Q8N8Q9

Explore proteomics data for NIPA2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8N8Q9

  • NIPA2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NIPA2 Protein Expression
    REFSEQ proteins (6 alternative transcripts): 
    NP_001008860.1  NP_001008892.1  NP_001008894.1  NP_001171817.1  NP_001171818.1  NP_112184.4  

    ENSEMBL proteins: 
     ENSP00000337618   ENSP00000381095   ENSP00000437746   ENSP00000352762   ENSP00000453700  
     ENSP00000381096  

    Human Recombinant Protein Products for NIPA2: 
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    Cloud-Clone Corp. Proteins for NIPA2 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005769early endosome IEA--
    GO:0005886plasma membrane IEA--
    GO:0016020membrane ----
    GO:0016021integral to membrane IEA--

    NIPA2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR008521 Mg_trans_NIPA

    Graphical View of Domain Structure for InterPro Entry Q8N8Q9

    ProtoNet protein and cluster: Q8N8Q9

    UniProtKB/Swiss-Prot: NIPA2_HUMAN, Q8N8Q9
    Similarity: Belongs to the NIPA family


    NIPA2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NIPA2_HUMAN, Q8N8Q9
    Function: Acts as a selective Mg(2+) transporter (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0015095magnesium ion transmembrane transporter activity IEA--
         
    NIPA2 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI phenotypic allele for Nipa2 (no phenotypes)

    NIPA2 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for NIPA2 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NIPA2 
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    SwitchGear 3'UTR luciferase reporter plasmidNIPA2 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NIPA2

    1 Interacting protein for NIPA2 (Q8N8Q93) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    C10orf35Q96D053I2D: score=2 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015693magnesium ion transport ----

    NIPA2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NIPA2

    Search CenterWatch for drugs/clinical trials and news about NIPA2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NIPA2 gene (6 alternative transcripts): 
    NM_001008860.2  NM_001008892.2  NM_001008894.2  NM_001184888.1  NM_001184889.1  NM_030922.6  

    Unigene Cluster for NIPA2:

    Non imprinted in Prader-Willi/Angelman syndrome 2
    Hs.591003  [show with all ESTs]
    Unigene Representative Sequence: NM_001184889
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000337451(uc001yvb.3 uc001yux.3 uc010ayb.3) ENST00000398013
    ENST00000539711 ENST00000359727 ENST00000560039 ENST00000561072 ENST00000559571
    ENST00000560205 ENST00000560762 ENST00000398014(uc001yuy.3 uc001yuz.3 uc001yva.3)

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    hsa-miR-548j hsa-miR-3653 hsa-miR-301a hsa-miR-578 hsa-miR-3658 hsa-miR-133a hsa-miR-548d-5p hsa-miR-548a-5p
    SwitchGear 3'UTR luciferase reporter plasmidNIPA2 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AK096305.1 AK300843.1 AK313584.1 AY732242.1 BC000957.3 BC011775.2 U90904.1 

    24/27 DOTS entries (see all 27):

    DT.451960  DT.99970876  DT.91865366  DT.121069748  DT.121069777  DT.101959366  DT.121069758  DT.75115206 
    DT.101974439  DT.121069762  DT.121069741  DT.100817146  DT.95121919  DT.102835933  DT.121069903  DT.91760312 
    DT.95121920  DT.100817144  DT.121069819  DT.65285070  DT.97847717  DT.97847720  DT.99938078  DT.100817142 

    24/348 AceView cDNA sequences (see all 348):

    AI078085 BE869856 AA912096 BC000957 CB121187 CR595946 N67361 CR606982 
    BE669926 BX338656 BQ614038 AW451958 BF060752 AW770149 BM807084 BQ428099 
    BC011775 CF139364 AA884012 BM723754 AY732242 BG390107 AI613524 BE783559 

    GeneLoc Exon Structure

    5/18 Alternative Splicing Database (ASD) splice patterns (SP) for NIPA2 (see all 18)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10a · 10b · 10c · 10d · 10e ^ 11 ^ 12 ^ 13 ^ 14a ·
    SP1:                                                  -     -     -                       -                                                     -     -         
    SP2:                                                        -     -           -     -     -                                                     -     -         
    SP3:                                -     -     -     -     -     -           -     -     -                                                     -     -         
    SP4:                                                                                                                                      -     -     -         
    SP5:                                                  -     -     -           -     -     -                                                                     

    ExUns: 14b ^ 15 ^ 16a · 16b
    SP1:                        
    SP2:                        
    SP3:                        
    SP4:                        
    SP5:                        


    ECgene alternative splicing isoforms for NIPA2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NIPA2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTATAATAAA
    NIPA2 Expression
    About this image


    See NIPA2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NIPA2

    SOURCE GeneReport for Unigene cluster: Hs.591003

    UniProtKB/Swiss-Prot: NIPA2_HUMAN, Q8N8Q9
    Tissue specificity: Widely expressed

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NIPA2 gene from 10/23 species (see all 23)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nipa21 , 5 non imprinted in Prader-Willi/Angelman syndrome 2 homolog more1, 5 90.71(n)1
    95.82(a)1
      7 (33.42 cM)5
    937901  NM_001256130.11  NP_001243059.11 
     559312875 
    chicken
    (Gallus gallus)
    Aves NIPA21 non imprinted in Prader-Willi/Angelman syndrome 2 79.63(n)
    85.83(a)
      418680  NM_001030809.1  NP_001025980.1 
    lizard
    (Anolis carolinensis)
    Reptilia NIPA26
    Uncharacterized protein
    85(a)
    1 ↔ 1
    3(111742434-111756410)
    African clawed frog
    (Xenopus laevis)
    Amphibia LOC3985542 hypothetical protein LOC398554 76.62(n)    BC046721.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb72g022 Danio rerio cDNA clone MGC66088 IMAGE6797300, complete more 74.25(n)    BC062386.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta spict1 spichthyin 54.64(n)
    51.61(a)
      34681  NM_135742.3  NP_609586.1 
    worm
    (Caenorhabditis elegans)
    Secernentea nipa-11 Protein NIPA-1 57.83(n)
    59.06(a)
      175418  NM_001129261.1  NP_001122733.1 
    A. gossypii yeast
    (Ashbya gossypii)
    Saccharomycetes AGOS_AER274W1 AER274Wp 50.52(n)
    45.99(a)
      4621342  NM_210485.1  NP_985131.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G719001 hypothetical protein 55.08(n)
    51.32(a)
      843521  NM_105848.4  NP_565027.1 
    rice
    (Oryza sativa)
    Liliopsida AK069309.12   -- 73.92(n)    AK069309.1 


    ENSEMBL Gene Tree for NIPA2 (if available)
    TreeFam Gene Tree for NIPA2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NIPA2 gene
    NIPA12  NIPAL32  NIPAL12  NIPAL22  NIPAL42  
    5 SIMAP similar genes for NIPA2 using alignment to 3 protein entries:     NIPA2_HUMAN (see all proteins):
    NIPAL1    NIPAL4    NIPA1    NIPAL2    NPAL2

    NIPA2 for paralogs           About GeneDecksing


    5 Pseudogenes.org Pseudogenes for NIPA2
    PGOHUM00000248644 PGOHUM00000239151 PGOHUM00000238069 PGOHUM00000232915 PGOHUM00000249407


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/877 SNPs in NIPA2 are shown (see all 877)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1448341311,2
    --1348104(+) ATGCAC/TTTTTT 6 -- us2k10--------
    rs1908466351,2
    --1348194(+) CCCCTC/GACCAC 6 -- us2k10--------
    rs71770351,2
    C,F,H--1348196(+) CCTGAC/TCACTC 6 -- us2k18Minor allele frequency- T:0.01NS EA NA WA 532
    rs1509457151,2
    --1348243(+) TAAAGC/GTTTTA 6 -- us2k10--------
    rs797060471,2
    F--1348258(+) GCCGTG/AAGCCT 6 -- us2k11Minor allele frequency- A:0.01EA 120
    rs1826495451,2
    --1348306(+) TTGCAA/TCTCAG 6 -- us2k10--------
    rs1851075371,2
    --2998547(+) ACCAAC/TTTTAA 6 -- ds50010--------
    rs1169852531,2
    C,F--2998606(+) TTTCCG/AGAGGC 6 -- ds50011Minor allele frequency- A:0.03NA 120
    rs1879854301,2
    --2998633(+) GAAGCA/GTATGA 6 -- ds50010--------
    rs284493731,2
    C,F--2998644(+) TGCACG/AGCACA 6 -- ds50017Minor allele frequency- A:0.28NA CSA WA EA 366

    HapMap Linkage Disequilibrium report for NIPA2 (23004684 - 23034427 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/39 variations for NIPA2 (see all 39):    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv471377CNV Deletion19718026
    dgv9n31CNV Deletion19718026
    esv2665115CNV Deletion23128226
    dgv44n16CNV Insertion17901297
    nsv471226CNV Loss18288195
    nsv437797CNV Loss16327808
    esv34233CNV Loss17911159
    nsv456636CNV Loss19166990
    nsv903560CNV Loss21882294
    dgv2234n71CNV Loss21882294


    Human Gene Mutation Database (HGMD): NIPA2
    SABiosciences Cancer Mutation PCR Assays
    1 SABiosciences qBiomarker Copy Number PCR Array containing NIPA2:
    Intellectual Disability
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 608146    OMIM disorders: --

    10 diseases for NIPA2:    About MalaCards
    microdeletion 15q11.2    prader-willi syndrome    angelman syndrome    autosomal recessive congenital ichthyosis
    ichthyosis    hereditary spastic paraplegia    paraplegia    spasticity
    prostate cancer    prostatitis

    2 diseases from the University of Copenhagen DISEASES database for NIPA2:
    Angelman syndrome     Prader-Willi syndrome

    NIPA2 for disorders           About GeneDecksing


    Export disorders for NIPA2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NIPA2 gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with NIPA2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of four highly conserved genes between breakpoint hotspots BP1 and BP2 of the Prader-Willi/Angelman syndromes deletion region that have undergone evolutionary transposition mediated by flanking duplicons. (PubMed id 14508708)1, 2, 3 Chai J.-H.... Nicholls R.D. (2003)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Nine patients with a microdeletion 15q11.2 between breakpoints 1 and 2 of the Prader-Willi critical region, possibly associated with behavioural disturbances. (PubMed id 19328872)1, 9 Doornbos M....van Ravenswaaij-Arts C.M. (2009)
    5. NIPA2 located in 15q11.2 is mutated in patients with c hildhood absence epilepsy. (PubMed id 22367439)1 Jiang Y....Wu X. (2012)
    6. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    7. Molecular identification of ancient and modern mammal ian magnesium transporters. (PubMed id 19940067)1 Quamme G.A. (2010)
    8. Analysis of the DNA sequence and duplication history of human chromosome 15. (PubMed id 16572171)2 Zody M.C....Nusbaum C. (2006)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    10. Expression of 4 genes between chromosome 15 breakpoints 1 and 2 and behavioral outcomes in Prader-Willi syndrome. (PubMed id 16982806)1 Bittel D.C....Butler M.G. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 81614 HGNC: 17044 AceView: NIPA2 Ensembl:ENSG00000140157 euGenes: HUgn81614
    ECgene: NIPA2 H-InvDB: NIPA2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NIPA2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NIPA2 gene:
    Search GeneIP for patents involving NIPA2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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