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Aliases & Descriptions for NIPA2
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc
, and/or 7 Ensembl ,
8 miRBase )About This Section
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Descriptions non imprinted in Prader-Willi/Angelman syndrome 2 2 non-imprinted in Prader-Willi/Angelman syndrome 2 2
Search outside databases for aliases for NIPA2 genePrevious GC identifers: GC15M020423 GC15M020553
Summaries for NIPA2 (According to Entrez Gene ,
Wikipedia's
Gene Wiki ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
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Gene Wiki entry for NIPA2
Genomic Location for NIPA2
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 36) ,
and/or miRBase ,
Genomic Views according to
UCSC and
Ensembl ,
Transcription factor binding sites according to
SABiosciences )About This Section
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Genomic View : UCSC Golden Path with GeneCards custom track Transcription factor binding sites upstream to the NIPA2 gene Entrez Gene cytogenetic band: 15q11.2 Ensembl cytogenetic band: 15q11.2 HGNC cytogenetic band: 15q11.2 NIPA2 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc gene densities for chromosome 15 GeneLoc Exon Structure
GeneLoc location for GC15M020556:
(about GC identifiers )
Start:
20,556,788 bp from pter
End:
20,585,849 bp from pter
Size:
29,062 bases
Orientation:
minus strand
RefSeq DNA sequence: NC_000015.8 NT_078094.1 Proteins for NIPA2
(According to
1 UniProtKB ,
and/or Ensembl ,
Phosphorylation sites according to 2 Phosphosite ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Enzo Life Sciences ,
Abnova ,
OriGene and/or,
Abcam ,
Biochemical Assays by
Invitrogen ,
Millipore ,
R&D Systems ,
Cell Signaling Technology , and/or
Enzo Life Sciences ,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene ,
Antibodies by Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Cell Signaling Technology ,
Abcam ,
Abnova , and/or
Novus Biologicals )
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UniProtKB/Swiss-Prot: NIPA2_HUMAN, Q8N8Q9 (See
protein sequence )Recommended Name: Non-imprinted in Prader-Willi/Angelman syndrome region protein 2 Size : 360 amino acids; 39185 Da
Subcellular location : Membrane; Multi-pass membrane protein (Potential)
Secondary accessions : Q96F03 Q9BVS2
Post-translational modifications:
View phosphorylation sites using PhosphoSite 2
REFSEQ proteins (4 alternative transcripts):
NP_001008860.1 NP_001008892.1 NP_001008894.1 NP_112184.4 ENSEMBL proteins: ENSP00000337618 ENSP00000352762 ENSP00000381096 ENSP00000381095 Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 2 Gene Ontology (GO) cellular component terms (links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0016020 membrane
IEA -- GO:0016021 integral to membrane
IEA --
About this table Antibodies for NIPA2: Assays for NIPA2:
Protein
Domains/ Families for NIPA2(According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
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Graphical View of Domain Structure for InterPro Entry Q8N8Q9 ProtoNet protein and cluster: Q8N8Q9
UniProtKB/Swiss-Prot: NIPA2_HUMAN, Q8N8Q9 Similarity : Belongs to the NIPA family
Gene Function for NIPA2
(According to MGI Jun 06 2009, UniProtKB ,
IUBMB ,and/or Genatlas ,
shRNA from
OriGene ,
Sigma-Aldrich , RNAi from
Sigma-Aldrich ,
RNAi Products ,
Clones , and
Q-PCR Products
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Millipore ,
OriGene , and/or
Abnova ,
siRNAs from
Applied Biosystems ,
SYBR primers from OriGene ,
Cell-based Assays from Millipore ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 4 ): NM_001008860 Applied Biosystems Silencer ® siRNAs for NIPA2 Sigma-Aldrich siRNA for NIPA2 Sigma-Aldrich shRNA for NIPA2 Explore Sigma-Aldrich super-pooled esiRNAs                OriGene GFP tagged cDNA clones in CMV expression vector (see all 4 ): NM_001008860                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 4 ): NM_001008860                                  untagged cDNA clones in CMV expression vector (see all 4 ): NM_001008860  Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_001008860 1 MGI phenotypic allele for Nipa2 (no phenotypes)1 Gene Ontology (GO) molecular function term (links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0005515 protein binding
IEA --
About this table
Pathways & Interactions for NIPA2
(Pathways according to Invitrogen
(maps by GeneGo ),
Millipore ,
Cell Signaling Technology ,
Sigma-Aldrich ,
KEGG
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Proteins Network according to
SABiosciences ,
Interactions according to 1 UniProtKB ,
2 MINT , and/or
3 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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4 Interacting proteins for NIPA2 (ENSP00000337618 3 ) via UniProtKB, MINT, and/or STRING About this table
Drugs & Compounds for NIPA2 (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
Sigma-Aldrich , Tocris Bioscience , and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB )
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Browse Tocris compounds for NIPA2
Transcripts for NIPA2(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
non coding RNAs according to
RNAdb ,
ESTs according to GeneTide ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from Invitrogen ,
Millipore , and/or
Abnova ,
siRNAs from Applied Biosystems ,
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shRNA from
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 4 ): NM_001008860 Sigma-Aldrich siRNA for NIPA2 Sigma-Aldrich shRNA for NIPA2 Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer ® siRNAs: NM_001008860 NM_001008892 NM_001008894 NM_030922
REFSEQ mRNAs for NIPA2 gene (4 alternative transcripts): NM_001008860.1 NM_001008892.1 NM_001008894.1 NM_030922.5
Applied Biosystems TaqMan ® Gene Expression Assays: NM_001008860 NM_001008892 NM_001008894 NM_030922
               OriGene GFP tagged cDNA clones in CMV expression vector (see all 4 ): NM_001008860                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 4 ): NM_001008860                                  untagged cDNA clones in CMV expression vector (see all 4 ): NM_001008860  
Additional cDNA sequence: AK096305.1 AK300843.1 AK313584.1 AY732242.1 BC000957.3 BC011775.2 CR598795.1 CR606982.1 CR625512.1 U90904.1
24/27 DOTS entries (see all 27
): DT.99970876 DT.451960 DT.91865366 DT.121069748 DT.101959366 DT.121069758 DT.121069777 DT.121069762 DT.75115206 DT.101974439 DT.121069741 DT.100817146 DT.95121919 DT.102835933 DT.121069903 DT.91760312 DT.95121920 DT.100817144 DT.121069819 DT.65285070 DT.97847717 DT.97847720 DT.99938078 DT.100817142
24/348 AceView cDNA sequences (see all 348
):CB121187 AA480270 BE669926 BU542017 BQ018262 BQ066545 AA890651 Z39245 BQ428099 AI962854 BM850398 BF970642 AI922763 AW770149 N67361 BM723754 BU153862 BU621473 AA912096 F09926 AI434382 AI453542 CB051159 BQ928926
highest scoring ESTs for NIPA2 :BC011775 BE735678 BE737509 BE784608 BE900924 BG708105 BG773477 BU542017 BX340598 CB155720
Unigene Cluster for NIPA2: Non imprinted in Prader-Willi/Angelman syndrome 2 Hs.591003 [show with all ESTs ] Unigene Representative Sequence: AY732242 GeneLoc Exon Structure 5/18 Alternative Splicing Database (ASD) splice patterns (SP) for NIPA2 (see all 18
) ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10a · 10b · 10c · 10d · 10e ^ 11 ^ 12 ^ 13 ^ 14a · SP1 :                 -   -   -         -                   -   -     SP2 :                   -   -     -   -   -                   -   -     SP3 :           -   -   -   -   -   -     -   -   -                   -   -     SP4 :                                             -   -   -     SP5 :                 -   -   -     -   -   -                        
ExUns: 14b ^ 15 ^ 16a · 16b SP1 :         SP2 :         SP3 :         SP4 :         SP5 :        
About this scheme ECgene alternative splicing isoforms for NIPA2 4 Ensembl transcripts including schematic representations : ENST00000337451
ENST00000359727
ENST00000398014
ENST00000398013
Expression for NIPA2
(Experimental results according to
1 GeneNote
and GNF BioGPS ,
probe sets-to-genes annotations according to
2 GeneAnnot ,
3 GeneTide ,
Sets of similar genes according to GeneDecks ,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP ,
plus additional links to
SOURCE , and/or
GNF
BioGPS , and/or
EXPOLDB , and/or
UniProtKB ,
Expression Assays from
Applied Biosystems
)
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NIPA2 expression in normal and diseased human tissues Applied Biosystems TaqMan ® Gene Expression Assays for NIPA2 1 / 2 / 3
2 probe-sets matching NIPA2 gene Data from
(Publications) and GNF BioGPS About these images About these images CGAP SAGE TAG: TTATAATAAASOURCE GeneReport for Unigene cluster: Hs.591003 Expression variation in blood from EXPOLDB for NIPA2
UniProtKB/Swiss-Prot: NIPA2_HUMAN, Q8N8Q9 Tissue specificity : Widely expressed
Orthologs for NIPA2
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
and/or
5 MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase ,
Gene Trees according to Ensembl )
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Orthologs for NIPA2 gene from 5/21 species (see all 21
)
About this table Species with no ortholog for NIPA2 ENSEMBL Gene Tree for NIPA2 Paralogs for NIPA2 (Paralogs according to 1 HomoloGene and 2 Ensembl , Pseudogenes according to 3 Pseudogene.org )About This Section
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Paralogs for NIPA2 gene NIPAL1 2 NIPAL4 2
SNPs/Variants for NIPA2 (According to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE , and
UniProtKB ,
Linkage Disequilibrium by HapMap ,
Genotyping Reagents from
Applied Biosystems )
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HapMap Linkage Disequilibrium images for NIPA2 (up to first 250kb)
Disorders & Mutations for NIPA2
(in which this Gene is Involved, According to
OMIM, UniProtKB ,
PharmGKB ,
Genatlas , GeneTests ,
Blood group antigen gene mutations by BGMUT ,
HGMD, GAD ,
HuGE Navigator ,
BCGD ,
and/or TGDB .)
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OMIM: 608146
Medical News for NIPA2 (Possibly Related Articles in
Doctor's Guide )
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--
Publications for NIPA2 (in
PubMed .
Associations of this gene to articles via
1 Novoseek ,
2 HGNC ,
3 Entrez Gene ,
4 UniProtKB/Swiss-Prot ,
5 UniProtKB/TrEMBL ,
6 GAD , and/or
7 PharmGKB )
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9 PubMed articles for NIPA2 gene :
Search for NIPA2
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing NIPA2
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
and/or
H-InvDB )
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Other Databases showing NIPA2
(According to HUGE )
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--
Specialized Databases showing NIPA2 (According to ATLAS , HORDE , IMGT , MTDB, LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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-- Services for NIPA2 (Reagents available from Applied Biosystems , Antibodies and assays by Cell
Signaling Technology , Abcam , Novus Biologicals ,Sigma-Aldrich , R&D Systems , Millipore , Abnova , and/or Invitrogen , Clones available from OriGene ,and/or Invitrogen , Drugs and/or compounds by Sigma-Aldrich , Enzo Life Sciences , and/or Tocris Bioscience )About This Section
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