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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NIPA1 Gene

protein-coding   GIFtS: 47
GCID: GC15M023043

non imprinted in Prader-Willi/Angelman syndrome 1

(Previous name: spastic paraplegia 6 (autosomal dominant) )
(Previous symbol: SPG6)
 Explore 11 diseases affiliated with
NIPA1 via our new
 Human Malady Compendium 
Biological research products
for NIPA1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Non Imprinted In Prader-Willi/Angelman Syndrome 11 2     Spastic Paraplegia 6 (Autosomal Dominant)1
SPG61 2 3 5     FSP32
Non-Imprinted In Prader-Willi/Angelman Syndrome Region Protein 12 3     Magnesium Transporter NIPA12
Spastic Paraplegia 6 Protein2 3     Non-Imprinted In Prader-Willi/Angelman Syndrome 12
MGC355701     

External Ids:    HGNC: 170431   Entrez Gene: 1236062   Ensembl: ENSG000001701137   OMIM: 6081455   UniProtKB: Q7RTP03   

Export aliases for NIPA1 gene to outside databases

Previous GC identifers: GC15M020462 GC00U914364 GC15M020594 GC15M001354


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NIPA1:
This gene encodes a magnesium transporter that associates with early endosomes and the cell surface in a variety of
neuronal and epithelial cells. This protein may play a role in nervous system development and maintenance. Multiple
transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been
associated with autosomal dominant spastic paraplegia 6. (provided by RefSeq, Nov 2008)

UniProtKB/Swiss-Prot: NIPA1_HUMAN, Q7RTP0
Function: Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+),
Mn(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity)

Gene Wiki entry for NIPA1


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000015.9  NC_018926.1  NT_078094.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NIPA1 gene promoter:
         AREB6   MZF-1   RREB-1   Roaz   C/EBPalpha   
         Other transcription factors

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Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NIPA1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q11.2   Ensembl cytogenetic band:  15q11.2   HGNC cytogenetic band: 15q11.2

NIPA1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NIPA1 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M023043:  view genomic region     (about GC identifiers)

Start:
23,043,277 bp from pter      End:
23,100,005 bp from pter
Size:
56,729 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: NIPA1_HUMAN, Q7RTP0 (See protein sequence)
Recommended Name: Magnesium transporter NIPA1  
Size: 329 amino acids; 34562 Da
Subunit: Homodimer (By similarity)
Subcellular location: Cell membrane; Multi-pass membrane protein (Potential). Early endosome (By similarity).
Note=Recruited to the cell membrane in response to low extracellular magnesium (By similarity)
Sequence caution: Sequence=BAC67707.1; Type=Erroneous initiation; Sequence=BAC67707.1; Type=Miscellaneous discrepancy;
Note=Contaminating sequence. Sequence of unknown origin in the N-terminal part;
Secondary accessions: B2RA76 Q5HYA9 Q7KZB0 Q86XW4
Alternative splicing: 2 isoforms:  Q7RTP0-1   Q7RTP0-2   

Explore the universe of human proteins at neXtProt for NIPA1: NX_Q7RTP0

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q7RTP0

  • NIPA1 Protein expression data from MOPED and PaxDb:    About this image 
    NIPA1 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001135747.1  NP_653200.2  

    ENSEMBL proteins: 
     ENSP00000337452   ENSP00000393962   ENSP00000453286   ENSP00000453722   ENSP00000453797  
     ENSP00000453237   ENSP00000440957  

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    Uscn Proteins for NIPA1

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005769early endosome IEA--
    GO:0005886plasma membrane IEA--
    GO:0016021integral to membrane IEA--

    NIPA1 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    NIPA1 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR008521 Mg_trans_NIPA

    Graphical View of Domain Structure for InterPro Entry Q7RTP0

    ProtoNet protein and cluster: Q7RTP0

    UniProtKB/Swiss-Prot: NIPA1_HUMAN, Q7RTP0
    Similarity: Belongs to the NIPA family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NIPA1_HUMAN, Q7RTP0
    Function: Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+),
    Mn(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity)

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015095magnesium ion transmembrane transporter activity IEA--
         
    NIPA1 for ontologies           About GeneDecksing


    Animal Models:
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    hsa-miR-134 hsa-miR-519a hsa-miR-3148 hsa-miR-130b hsa-miR-877 hsa-miR-4324 hsa-let-7i hsa-miR-138-1*
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NIPA1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NIPA1

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008219cell death IEA--
    GO:0015693magnesium ion transport ----

    NIPA1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NIPA1
    Search CenterWatch for drugs/clinical trials and news about NIPA1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NIPA1 gene (2 alternative transcripts): 
    NM_001142275.1  NM_144599.4  

    Unigene Cluster for NIPA1:

    Non imprinted in Prader-Willi/Angelman syndrome 1
    Hs.511797  [show with all ESTs]
    Unigene Representative Sequence: NM_144599
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000337435(uc001yvc.3 uc001yvd.3 uc001yve.3) ENST00000437912
    ENST00000559448 ENST00000561183 ENST00000557930 ENST00000560069 ENST00000560105
    ENST00000538684

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    8/66 QIAGEN miScript miRNA Assays for microRNAs that regulate NIPA1 (see all 66):
    hsa-miR-134 hsa-miR-519a hsa-miR-3148 hsa-miR-130b hsa-miR-877 hsa-miR-4324 hsa-let-7i hsa-miR-138-1*
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    OriGene shRNA RFP: NIPA1
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    Additional cDNA sequence: 

    AB089319.1 AK057846.1 AK314073.1 BC025678.1 BX648722.1 

    10 DOTS entries:

    DT.437484  DT.40107417  DT.92044496  DT.100020976  DT.91738716  DT.442962  DT.121067137  DT.121067199 
    DT.100680962  DT.100775180 

    24/157 AceView cDNA sequences (see all 157):

    CF242938 AA382746 AI241769 CA432413 BX477168 AW672996 BQ000945 BI768470 
    BQ433728 BM758148 BE465270 BU618304 AI420788 BE502247 AA905257 CA398063 
    T36044 BM968101 AI439250 AW339542 CR614719 BC025678 BK001020 BU147357 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for NIPA1    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b · 8c · 8d
    SP1:                                      -     -                                             
    SP2:                                                  -                                       
    SP3:        -     -     -                 -     -     -                                       
    SP4:                                      -     -     -                                       
    SP5:                                                                                          


    ECgene alternative splicing isoforms for NIPA1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NIPA1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --
    NIPA1 Expression
    About this image
    See NIPA1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NIPA1

    SOURCE GeneReport for Unigene cluster: Hs.511797

    UniProtKB/Swiss-Prot: NIPA1_HUMAN, Q7RTP0
    Tissue specificity: Widely expressed with highest levels in neuronal tissues

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NIPA1 gene from 5/18 species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves NIPA11 non imprinted in Prader-Willi/Angelman syndrome 1 72.41(n)
    85.54(a)
      418681  XM_003640526.1  XP_003640574.1 
    lizard
    (Anolis carolinensis)
    Reptilia NIPA16
    --
    95(a)
    1 ↔ 1
    3(111701356-111710681)
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.242272 Transcribed sequence with weak similarity to protein more 69.18(n)    CK395911.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G211206
    AT4G387306
    (see all 7)
    uncharacterized protein
    (see all 7)
    36(a)
    34(a)
    (see all 7)
    many ↔ many
    many ↔ many
    (see all 7)
    2(9051748-9054613)
    4(18080233-18082537)
    rice
    (Oryza sativa)
    Liliopsida --
    --
    (see all 9)
    DUF803 domain containing, putative, expressed
    (see all 9)
    34(a)
    33(a)
    (see all 9)
    many ↔ many
    many ↔ many
    (see all 9)
    5(21072679-21076056)
    5(20744498-20748759)


    ENSEMBL Gene Tree for NIPA1 (if available)
    TreeFam Gene Tree for NIPA1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NIPA1 gene
    NIPAL32  NIPAL12  NIPAL22  NIPA22  NIPAL42  
    3 SIMAP similar genes for NIPA1 using alignment to 7 protein entries:     NIPA1_HUMAN (see all proteins):
    NIPAL1    NIPA2    NIPAL4

    NIPA1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/850 NCBI SNPs in NIPA1 are shown (see all 850    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1048944961,2
    Cpathogenic23086278(-) GTCCAC/GGTTCG 3 T R mis1 int10--------
    rs1893109671,2
    --23042803(+) AGCCAA/CCACAC 2 -- ds50010--------
    rs620011081,2
    C--23042814(+) CTGGCC/TCACAG 2 -- ds50013Minor allele frequency- T:0.07NA EA 242
    rs734126801,2
    C--23042828(+) GACATT/CTTCTA 2 -- ds50012Minor allele frequency- C:0.21WA 120
    rs106041051,2
    C--23042871(+) CTGTC-/TTTTTTT 2 -- ds50010--------
    rs344814261,2
    C--23042871(-) AAAAA-/AGACAG 2 -- ds50011Minor allele frequency- A:0.00CSA 2
    rs1142321841,2
    F--23042934(+) ATCTCG/CGTCAC 2 -- ds50011Minor allele frequency- C:0.04WA 118
    rs1439232821,2
    --23043016(+) GCACCA/CCCATG 2 -- ds50010--------
    rs116376241,2
    C,H--23043081(+) ggctgA/Gtctca 2 -- ds50010--------
    rs71621311,2
    C,F,A--23043158(+) actgcA/Tcccag 2 -- ds50016Minor allele frequency- T:0.08NA WA EA 364

    HapMap Linkage Disequilibrium report for NIPA1 (23043277 - 23100005 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 25 variations for NIPA1
         15/22 CNVs (see all 22): 38872 4878 37594 87485 49473 9256 9251 49472 49471 5773 102046 8787 3070 3951 34608
         3 Indels: 25479 45321 41699
    Human Gene Mutation Database (HGMD): NIPA1

    SABiosciences Cancer Mutation PCR Assays
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    DNA2.0 Custom Variant and Variant Library Synthesis for NIPA1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    NIPA1 for disorders           About GeneDecksing

    OMIM gene information: 608145   
    OMIM disorders: 600363  
    UniProtKB/Swiss-Prot: NIPA1_HUMAN, Q7RTP0
  • Defects in NIPA1 are the cause of spastic paraplegia autosomal dominant type 6 (SPG6) [MIM:600363]. Spastic
  • paraplegia is a degenerative spinal cord disorder characterized by a slow, gradual, progressive weakness and
    spasticity of the lower limbs

    11 diseases for NIPA1:    About MalaCards
    spastic paraplegia 6    spastic paraplegia    paraplegia    spasticity
    angelman syndrome    autosomal recessive congenital ichthyosis    prader-willi syndrome    hereditary spastic paraplegia
    ichthyosis    neuronitis    multiple sclerosis

    2 diseases from the University of Copenhagen DISEASES database for NIPA1:
    Paraplegia     Angelman syndrome

    3 Novoseek disease relationships for NIPA1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    spastic paraplegia hereditary autosomal dominant 95 3 14508710 (1), 17928003 (1), 15643603 (1)
    spastic paraplegia hereditary 91.2 2 16267846 (1), 19738379 (1)
    spastic paraplegia 75.9 2 16267846 (1), 15317751 (1)

    Human Genome Epidemiology (HuGE) Navigator: NIPA1 (3 documents)

    Export disorders for NIPA1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NIPA1 gene, integrated from 9 sources (see all 28):
    (articles sorted by number of sources associating them with NIPA1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. NIPA1 gene mutations cause autosomal dominant hereditary spastic paraplegia (SPG6). (PubMed id 14508710)1, 2, 3, 9 Rainier S.... Fink J.K. (2003)
    2. Distinct novel mutations affecting the same base in the NIPA1 gene cause autosomal dominant hereditary spastic paraplegia in two Chinese families. (PubMed id 15643603)1, 2, 9 Chen S.... Wang Y. (2005)
    3. Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)1, 2 Liu T.... Smith R.D. (2005)
    4. Analysis of mRNA with microsomal fractionation using a SAGE-based DNA microarray system facilitates identification of the genes encoding secretory proteins. (PubMed id 12805275)1, 2 Toyoda N.... Matsushima K. (2003)
    5. Identification of four highly conserved genes between breakpoint hotspots BP1 and BP2 of the Prader-Willi/Angelman syndromes deletion region that have undergone evolutionary transposition mediated by flanking duplicons. (PubMed id 14508708)1, 2 Chai J.-H.... Nicholls R.D. (2003)
    6. Hereditary spastic paraplegia-associated mutations in the NIPA1 gene and its Caenorhabditis elegans homolog trigger neural degeneration in vitro and in vivo through a gain-of-function mechanism. (PubMed id 19091982)1, 9 Zhao J....Hedera P. (2008)
    7. NIPA1(SPG6), the basis for autosomal dominant form of hereditary spastic paraplegia, encodes a functional Mg2+ transporter. (PubMed id 17166836)1, 9 Goytain A....Quamme G.A. (2007)
    8. Clinical and genetic study of a Brazilian family with spastic paraplegia (SPG6 locus). (PubMed id 16267846)1, 9 Munhoz R.P....Rogaeva E. (2006)
    9. Clinical and genetic study of SPG6 mutation in a Chinese family with hereditary spastic paraplegia. (PubMed id 17928003)1, 9 Liu S.G....Ma X. (2008)
    10. NIPA1 polyalanine repeat expansions are associated wit h amyotrophic lateral sclerosis. (PubMed id 22378146)1 Blauw H.M....van den Berg L.H. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 123606 HGNC: 17043 AceView: NIPA1 Ensembl:ENSG00000170113 euGenes: HUgn123606
    ECgene: NIPA1 H-InvDB: NIPA1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NIPA1 Pharmacogenomics, SNPs, Pathways
    GeneReviewshttp://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/NIPA1

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NIPA1 gene:
    Search GeneIP for patents involving NIPA1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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