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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NINL Gene

protein-coding   GIFtS: 50
GCID: GC20M025383

ninein-like

 Explore 12 diseases affiliated with
NINL via our new
 Human Malady Compendium 
Biological research products
for NINL
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Ninein-Like1
NLP1 2 3
KIAA09801 3
DJ691N24.11
Ninein-Like Protein2

External Ids:    HGNC: 291631   Entrez Gene: 229812   Ensembl: ENSG000001010047   OMIM: 6095805   UniProtKB: Q9Y2I63   

Export aliases for NINL gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: NINL_HUMAN, Q9Y2I6
Function: Involved in the microtubule organization in interphase cells. Overexpression induces the fragmentation of the
Golgi, and causes lysosomes to disperse toward the cell periphery; it also interferes with mitotic spindle assembly.
May play a role in ovarian carcinogenesis

Gene Wiki entry for NINL


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NC_018931.1  NT_011387.8  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NINL gene promoter:
         ER-alpha   Sp1   FOXF2   Nkx2-5   Tal-1beta   NF-E2 p45   Egr-4   HFH-1   ITF-2   NF-E2   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for NINL

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NINL


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20p11.22-p11.1   Ensembl cytogenetic band:  20p11.21   HGNC cytogenetic band: 20p11.22-p11.1

NINL Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NINL gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20M025383:  view genomic region     (about GC identifiers)

Start:
25,433,337 bp from pter      End:
25,566,153 bp from pter
Size:
132,817 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: NINL_HUMAN, Q9Y2I6 (See protein sequence)
Recommended Name: Ninein-like protein  
Size: 1382 amino acids; 156344 Da
Subunit: Interacts with gamma-tubulin and TUBGCP4. Interacts with anaphase promoting complex/cyclosome (APC/C).
Interacts with CDC20 and FZR1. Isoform 2 interacts with LCA5 and USH2A
Subcellular location: Cytoplasm, cytoskeleton, centrosome. Cytoplasm. Note=In interphase cells, NINL is transported to
the centrosomes by the dynein-dynactin motor complex. During centrosome maturation, PLK1 directly phosphorylates NINL
resulting in its release into the cytoplasm
Sequence caution: Sequence=BAA76824.1; Type=Erroneous initiation; Sequence=BAH11644.1; Type=Erroneous initiation;
Note=Translation N-terminally extended; Sequence=BAH11644.1; Type=Erroneous termination; Positions=405;
Note=Translated as Gln;
Secondary accessions: A6NJN0 B3V9H6 B7Z1V8 Q5JYP0 Q8NE38 Q9NQE3
Alternative splicing: 2 isoforms:  Q9Y2I6-1   Q9Y2I6-2   

Explore the universe of human proteins at neXtProt for NINL: NX_Q9Y2I6

Post-translational modifications:

  • Phosphorylated by PLK1 which disrupts its centrosome association and interaction with gamma-tubulin1
  • Ubiquitinated by the APC/C complex leading to its degradation1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9Y2I6

  • NINL Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_079452.3  
    ENSEMBL proteins: 
     ENSP00000278886   ENSP00000338621   ENSP00000410431  
    Reactome Protein details: Q9Y2I6
    Human Recombinant Protein Products: 
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for NINL

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005815microtubule organizing center IEA--
    GO:0005829cytosol TAS--
    GO:0005874microtubule IEA--


    NINL for ontologies           About GeneDecksing



    NINL Antibody Products: 
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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    NINL for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR018247 EF_Hand_1_Ca_BS
     IPR011992 EF-hand-like_dom
     IPR002048 EF_hand_Ca-bd

    Graphical View of Domain Structure for InterPro Entry Q9Y2I6

    ProtoNet protein and cluster: Q9Y2I6

    UniProtKB/Swiss-Prot: NINL_HUMAN, Q9Y2I6
    Domain: The KEN and D (destructive) boxes are required for the cell cycle-controlled NINL degradation by the APC/C
    pathway
    Similarity: Contains 4 EF-hand domains


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: NINL_HUMAN, Q9Y2I6
    Function: Involved in the microtubule organization in interphase cells. Overexpression induces the fragmentation of the
    Golgi, and causes lysosomes to disperse toward the cell periphery; it also interferes with mitotic spindle assembly.
    May play a role in ovarian carcinogenesis

    miRNA
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    8/17 QIAGEN miScript miRNA Assays for microRNAs that regulate NINL (see all 17):
    hsa-miR-137 hsa-miR-25 hsa-miR-548a-3p hsa-miR-633 hsa-miR-199b-5p hsa-miR-92b hsa-miR-3163 hsa-miR-92a
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NINL

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding IEA--


    NINL for ontologies           About GeneDecksing



    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Recruitment of mitotic centrosome proteins and complexes
    Centrosome maturation1.00
    Mitotic G2-G2/M phases0.81
    Recruitment of mitotic centrosome proteins and complexes1.00
    Loss of proteins required for interphase microtubule organization from the centrosome0.78
    G2/M Transition0.83
    Loss of Nlp from mitotic centrosomes0.78
    2Cell Cycle
    Cell Cycle1.00
    Cell Cycle, Mitotic0.84
    3PLK1 signaling events
    PLK1 signaling events1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 BioSystems Pathway for NINL 
        PLK1 signaling events

    5/8        Reactome Pathways for NINL (see all 8)
        Centrosome maturation
    Cell Cycle
    Recruitment of mitotic centrosome proteins and complexes
    G2/M Transition
    Loss of proteins required for interphase microtubule organization from the centrosome



    NINL for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NINL

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/118 Interacting proteins for NINL (Q9Y2I62, 3 ENSP000002788864) via UniProtKB, MINT, STRING, and/or I2D (see all 118)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    APEX2Q9UBZ42, 3, ENSP000003641264MINT-67835 I2D: score=5 STRING: ENSP00000364126
    GPKOWQ929172, 3, ENSP000001561094MINT-66821 I2D: score=5 STRING: ENSP00000156109
    KAT7O952512, 3, ENSP000002590214MINT-67724 I2D: score=5 STRING: ENSP00000259021
    MAD1L1Q9Y6D92, 3, ENSP000003825624MINT-66346 I2D: score=5 STRING: ENSP00000382562
    MBIPQ9NS732, 3, ENSP000003244444MINT-68225 I2D: score=5 STRING: ENSP00000324444
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000086G2/M transition of mitotic cell cycle TAS--
    GO:0000278mitotic cell cycle TAS--


    NINL for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NINL
    Search CenterWatch for drugs/clinical trials and news about NINL 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NINL gene: 
    NM_025176.4  

    Unigene Cluster for NINL:

    Ninein-like
    Hs.631508  [show with all ESTs]
    Unigene Representative Sequence: NM_025176
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000278886(uc002wux.1) ENST00000464285(uc002wuw.1) ENST00000496509
    ENST00000336104 ENST00000489780 ENST00000461642 ENST00000422516(uc010ztf.1 uc010gdn.1 uc010gdo.1)


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    hsa-miR-137 hsa-miR-25 hsa-miR-548a-3p hsa-miR-633 hsa-miR-199b-5p hsa-miR-92b hsa-miR-3163 hsa-miR-92a
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NINL
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NINL

    Additional cDNA sequence: 

    AB023197.1 AK021854.1 AK093569.1 AK293991.1 AK309298.1 BC036380.2 BC113094.1 EU718622.1 

    12 DOTS entries:

    DT.112811  DT.100023470  DT.100749001  DT.91751570  DT.95366673  DT.91797802  DT.40229147  DT.40301667 
    DT.91719162  DT.91847552  DT.97779713  DT.97807014 

    24/130 AceView cDNA sequences (see all 130):

    AA148595 BE670018 AA890134 BM272814 AI937939 AA205072 BP352100 BE549664 
    BM875349 W63779 AI631012 AA148761 AV705052 AA610759 BF433031 AL134587 
    BU687429 AI126974 AB023197 BI914911 D31019 AI024623 AV703170 AA932529 

    GeneLoc Exon Structure

    5/13 Alternative Splicing Database (ASD) splice patterns (SP) for NINL (see all 13)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15a · 15b ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^
    SP1:        -     -                                                                                                                                             
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:              -                                                                                                                                             
    SP5:                                                                                                                                                            

    ExUns: 22 ^ 23 ^ 24a · 24b ^ 25a · 25b ^ 26 ^ 27a · 27b
    SP1:                                                      
    SP2:  -                                                   
    SP3:                          -                           
    SP4:                                                      
    SP5:                                                      


    ECgene alternative splicing isoforms for NINL

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NINL expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TGGTGCTTCC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See NINL Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NINL

    SOURCE GeneReport for Unigene cluster: Hs.631508

    UniProtKB/Swiss-Prot: NINL_HUMAN, Q9Y2I6
    Tissue specificity: Expressed in KYSE-150 esophageal carcinoma, HeLa cervical carcinoma and U2OS osteosarcoma cells.
    Expression is regulated in a cell cycle-dependent manner and peaks during G2/M phase (at protein level). Expressed in
    fetal heart, skeletal muscle, liver, lung and cochlea, and in adult brain, testis, kidney and retina

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the last universal common ancestor (LUCA).

    Orthologs for NINL gene from 6/22 species (see all 22)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    lizard
    (Anolis carolinensis)
    Reptilia NINL6
    --
    39(a)
    1 ↔ 1
    1(254246308-254281465)
    zebrafish
    (Danio rerio)
    Actinopterygii akap96
    CABZ01072067.16
    --
    5(a)
    48(a)
    possible ortholog
    1 ↔ 1
    19(530667-565004)
    13(6999808-7026723)
    fruit fly
    (Drosophila melanogaster)
    Insecta Tig6
    Tiggrin
    5(a)
    1 ↔ 1
    2L(6415257-6423308)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G220606
    AT4G380706
    basic helix-loop-helix domain-containing protein
    5(a)
    4(a)
    1 ↔ 1
    possible ortholog
    1(7773063-7781499)
    4(17876535-17882569)
    rice
    (Oryza sativa)
    Liliopsida --
    --
    (see all 5)
    expressed protein
    (see all 5)
    7(a)
    7(a)
    (see all 5)
    possible ortholog
    1 ↔ many
    (see all 5)
    1(26698145-26705114)
    3(439339-446586)
    E. coli
    (Escherichia coli)
    Gamma proteobacteria mukB6
    chromosome condensin MukBEF, ATPase and DNA-bindin...
    5(a)
    1 ↔ 1
    Chromosome(975549-980009)


    ENSEMBL Gene Tree for NINL (if available)
    TreeFam Gene Tree for NINL (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NINL gene
    NIN2  

    NINL for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2590 NCBI SNPs in NINL are shown (see all 2590    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2019068261,2
    Cother25459729(+) AGGTCA/GGCCTT 2 A syn10--------
    rs1908366671,2
    --25432880(+) AGAGTC/TTTCCT 1 -- ds50010--------
    rs1839613381,2
    --25433007(+) ATCAGG/TAAACT 1 -- ds50010--------
    rs1128282451,2
    C--25433015(-) TTCTTC/TAAAGT 1 -- ds50010--------
    rs1875991511,2
    --25433249(+) TGATGC/GGCACA 1 -- ds50010--------
    rs1922214211,2
    --25433306(+) ATAGTA/TTAAAA 1 -- ds50010--------
    rs58410581,2
    C--25433448(+) TTTTTT/-ACATA 1 -- ut311Minor allele frequency- -:0.00NA 2
    rs28561,2
    C,F,A,H,--25433536(+) ATCATC/TCCTGA 1 -- ut31 ese332Minor allele frequency- T:0.42MN NS EA NA WA CSA 2864
    rs1444398281,2
    --25433560(+) GTCCCC/TGGAGA 1 -- ut310--------
    rs1392429011,2
    --25433561(+) TCCCCA/GGAGAA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for NINL (25433337 - 25566153 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 3 variations for NINL
         2 CNVs: 35913 73489
         1 Indel: 12174

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    NINL for disorders           About GeneDecksing

    OMIM gene information: 609580    OMIM disorders: --

    12 diseases for NINL:    About MalaCards
    leber congenital amaurosis    usher syndrome    squamous cell carcinoma    ptosis
    esophageal carcinoma    cervical carcinoma    esophagitis    cervicitis
    ovarian cancer    osteosarcoma    carcinoma    malaria

    1 disease from the University of Copenhagen DISEASES database for NINL:
    Usher syndrome

    Export disorders for NINL gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NINL gene, integrated from 9 sources (see all 24):
    (articles sorted by number of sources associating them with NINL)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10231032)1, 2, 3 Nagase T.... Ohara O. (1999)
    2. Usher syndrome and Leber congenital amaurosis are molecularly linked via a novel isoform of the centrosomal ninein-like protein. (PubMed id 18826961)1, 2 van Wijk E.... Kremer H. (2009)
    3. Increased expression of Nlp, a potential oncogene in ovarian cancer, and its implication in carcinogenesis. (PubMed id 18538832)1, 2 Qu D.... Zhan Q. (2008)
    4. Cell cycle-dependent expression of centrosomal ninein-like protein in human cells is regulated by the anaphase-promoting complex. (PubMed id 17403670)1, 2 Wang Y. and Zhan Q. (2007)
    5. Phosphorylation of Nlp by Plk1 negatively regulates its dynein- dynactin-dependent targeting to the centrosome. (PubMed id 16254247)1, 2 Casenghi M.... Nigg E.A. (2005)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    8. Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation. (PubMed id 12852856)1, 2 Casenghi M....Nigg E.A. (2003)
    9. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
    10. Overexpression of centrosomal protein Nlp confers brea st carcinoma resistance to paclitaxel. (PubMed id 22353935)1 Zhao W....Zhan Q. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 22981 HGNC: 29163 AceView: KIAA0980 Ensembl:ENSG00000101004 euGenes: HUgn22981
    ECgene: NINL H-InvDB: NINL

    (According to HUGE)
    About This Section
    HUGE: KIAA0980

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NINL Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NINL gene:
    Search GeneIP for patents involving NINL

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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