Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



NIM1K Gene

protein-coding   GIFtS: 36
GCID: GC05P043194

NIM1 Serine/Threonine Protein Kinase

  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
NIM1 Serine/Threonine Protein Kinase1 2
NIM12 3
NIM1 Serine/Threonine-Protein Kinase2 3
EC 2.7.11.13 8
Serine/Threonine-Protein Kinase NIM12
EC 2.7.118

External Ids:    HGNC: 286461   Entrez Gene: 1673592   Ensembl: ENSG000001774537   UniProtKB: Q8IY843   
ORGUL members:         

Export aliases for NIM1K gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for NIM1K Gene:
NIM1K (NIM1 serine/threonine protein kinase) is a protein-coding gene. An important paralog of this gene is BRSK1.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000005.9  NT_006576.17  NC_018916.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for NIM1K
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for NIM1K

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NIM1K


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5p12   Ensembl cytogenetic band:  5p12   HGNC cytogenetic band: 5p12

NIM1K Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NIM1K gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P043194:  view genomic region     (about GC identifiers)

Start:
43,192,173 bp from pter      End:
43,280,952 bp from pter
Size:
88,780 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: NIM1_HUMAN, Q8IY84 (See protein sequence)
Recommended Name: Serine/threonine-protein kinase NIM1  
Size: 436 amino acids; 49606 Da
Cofactor: Magnesium
Secondary accessions: B3KVM1

Explore the universe of human proteins at neXtProt for NIM1K: NX_Q8IY84

Explore proteomics data for NIM1K at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • 2 DME Specific Peptides for NIM1K (Q8IY84)
     IIHRDLKA  GSPPYAAPE 


    See NIM1K Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_699192.1  
    ENSEMBL proteins: 
     ENSP00000313572   ENSP00000420849  

    NIM1K Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for NIM1K
    Browse OriGene Protein Over-expression Lysates
    OriGene MassSpec for NIM1K
    OriGene Custom Protein Services for NIM1K
    GenScript Custom Purified and Recombinant Proteins Services for NIM1K
    Novus Biologicals NIM1K Proteins
    Novus Biologicals NIM1K Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for NIM1K 

     
    antibodies-online proteins for NIM1K (5 products) 

     
    antibodies-online peptides for NIM1K

    NIM1K Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for NIM1K
    OriGene Custom Antibody Services for NIM1K
    Novus Biologicals NIM1K Antibodies
    Search for Antibodies for NIM1K at Abcam
    Browse Antibodies at Cloud-Clone Corp.
    ThermoFisher Antibodies for NIM1K
    antibodies-online antibodies for NIM1K (26 products) 

    NIM1K Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for NIM1K
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for NIM1K
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for NIM1K 
    antibodies-online kits for NIM1K (2 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    5 InterPro protein domains:
     IPR017441 Protein_kinase_ATP_BS
     IPR002290 Ser/Thr_dual-sp_kinase_dom
     IPR011009 Kinase-like_dom
     IPR008271 Ser/Thr_kinase_AS
     IPR000719 Prot_kinase_dom

    Graphical View of Domain Structure for InterPro Entry Q8IY84

    ProtoNet protein and cluster: Q8IY84

    UniProtKB/Swiss-Prot: NIM1_HUMAN, Q8IY84
    Similarity: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family
    Similarity: Contains 1 protein kinase domain


    Find genes that share domains with NIM1K           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NIM1_HUMAN, Q8IY84
    Catalytic activity: ATP + a protein = ADP + a phosphoprotein
    Enzyme regulation: Activated by phosphorylation at Thr-229, probably by autophosphorylation

         Enzyme Numbers (IUBMB): EC 2.7.11.11 2 EC 2.7.112

         Gene Ontology (GO): Selected molecular function terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000287magnesium ion binding IDA15733851
    GO:0004672protein kinase activity ----
    GO:0004674protein serine/threonine kinase activity IDA15733851
    GO:0004713protein tyrosine kinase activity ----
    GO:0005524ATP binding IDA15733851
         
    Find genes that share ontologies with NIM1K           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for NIM1K:
     Decreased substrate adherent c 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for NIM1K

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat NIM1K using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate NIM1K
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for NIM1K
    Predesigned siRNA for gene silencing in human, mouse, rat NIM1K

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for NIM1K

    Clone
    Products:
         
    OriGene clones in human, mouse for NIM1K (see all 8)
    OriGene ORF clones in mouse, rat for NIM1K
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for NIM1K
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NIM1K
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NIM1K
    Addgene plasmids for NIM1K 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for NIM1K
    Browse ESI BIO Cell Lines and PureStem Progenitors for NIM1K 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NIM1K


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus
      --

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NIM1K
    Interactions:

        Search GeneGlobe Interaction Network for NIM1K

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    Selected Interacting proteins for NIM1K (ENSP000003135724) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPTORENSP000003072724STRING: ENSP00000307272
    CCNB1ENSP000002564424STRING: ENSP00000256442
    CCNB2ENSP000002882074STRING: ENSP00000288207
    CHEK1ENSP000002789164STRING: ENSP00000278916
    SEPT12ENSP000002682314STRING: ENSP00000268231
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006468protein phosphorylation IDA15733851

    Find genes that share ontologies with NIM1K           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NIM1K (NIM1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for NIM1K gene: 
    NM_153361.3  

    Unigene Cluster for NIM1K:

    Serine/threonine-protein kinase NIM1
    Hs.25845  [show with all ESTs]
    Unigene Representative Sequence: NR_072980
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000509362 ENST00000326035(uc003jno.3) ENST00000513797 ENST00000440285
    ENST00000512796
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat NIM1K using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate NIM1K
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for NIM1K
    Predesigned siRNA for gene silencing in human, mouse, rat NIM1K
    Clone
    Products:
         
    OriGene clones in human, mouse for NIM1K (see all 8)
    OriGene ORF clones in mouse, rat for NIM1K
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for NIM1K
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NIM1K
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NIM1K
    Addgene plasmids for NIM1K 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for NIM1K
    OriGene qSTAR qPCR primer pairs in human, mouse for NIM1K
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat NIM1K
      QuantiTect SYBR Green Assays in human, mouse, rat NIM1K
      QuantiFast Probe-based Assays in human, mouse, rat NIM1K

    Additional mRNA sequence: 

    AK122985.1 BC036422.2 NR_072980.1 

    3 DOTS entries:

    DT.410121  DT.101965504  DT.100744887 

    Selected AceView cDNA sequences (see all 28):

    AK122985 BQ447856 AW138655 BE551926 AI335850 BQ673362 BG709047 AI949037 
    BU727953 BC036422 BQ635881 NM_153361 BM686574 CB990247 BX112667 CB997450 
    AI609751 CB995976 AW138653 AA912775 BF222940 R59486 R53564 R59487 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    NIM1K expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    NIM1K Expression
    About this image

    NIM1K Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NIM1K Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.25845
        Custom PCR Arrays for NIM1K
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for NIM1K
    OriGene qSTAR qPCR primer pairs in human, mouse for NIM1K
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat NIM1K
    QuantiTect SYBR Green Assays in human, mouse, rat NIM1K
    QuantiFast Probe-based Assays in human, mouse, rat NIM1K
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NIM1K

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for NIM1K gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nim15
    Nim1k1
    RIKEN cDNA E130304F04 gene5
    NIM1 serine/threonine protein kinase1
    87.23(n)1
    91.74(a)1
      135
    2452691  NM_175538.31  NP_780747.11 
     1197100945 
    chicken
    (Gallus gallus)
    Aves NIM11 serine/threonine-protein kinase NIM1 73.09(n)
    77.98(a)
      768482  NM_001252130.1  NP_001239059.1 
    lizard
    (Anolis carolinensis)
    Reptilia NIM1K6
    NIM1 serine/threonine protein kinase
    74(a)
    1 ↔ 1
    2(6168095-6186779)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia LOC1004912671 serine/threonine-protein kinase NIM1-like 73.62(n)
    76.15(a)
      100491267  XM_002933034.2  XP_002933080.2 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1005363361 serine/threonine-protein kinase NIM1-like 68.15(n)
    71.13(a)
      100536336  XM_003199103.2  XP_003199151.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG46296
    --
    31(a)
    1 ↔ 1
    2L(1083091-1102504)
    worm
    (Caenorhabditis elegans)
    Secernentea F49C5.41 F49C5.4 53.8(n)
    47.15(a)
      186015  NM_064278.3  NP_496679.3 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes HSL16
    GIN46
    (see all 3)
    Nim1p-related protein kinase that regulates the mo...
    Protein kinase involved in bud growth and assembly...
    (see all 3)
    8(a)
    10(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    XI(248920-253476) YKL101W
    IV(1462358-1465786) YDR507C


    ENSEMBL Gene Tree for NIM1K (if available)
    TreeFam Gene Tree for NIM1K (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for NIM1K gene
    BRSK12  MARK12  BRSK22  SNRK2  SIK32  SIK22  MARK22  SIK12  
    MARK42  MARK32  
    Selected SIMAP similar genes for NIM1K using alignment to 1 protein entry:     NIM1_HUMAN(see all similar genes):
    MARK2    Par1b    KIAA0999    SIK1    SIK3    PRKAA1
    MARK3    MARK1    PNCK    PRKAA2    BRSK2    CAMK1
    CAMK1D    PRKY    SNRK    TSSK6    TSSK2    TSSK3

    Find genes that share paralogs with NIM1K           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for NIM1K (see all 2111)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0409494
    A lung neuroendocrine carcinoma sample4--see VAR_0409492 P S mis40--------
    VAR_0409504
    A lung large cell carcinoma sample4--see VAR_0409502 P T mis40--------
    rs1451522601,2
    C--43190297(+) AATTAC/TATTTG 1 -- us2k10--------
    rs1475757611,2
    --43190557(+) TTAACG/TCCCAA 1 -- us2k10--------
    rs1888942821,2
    C--43190559(+) AACTCA/CCAATG 1 -- us2k10--------
    rs798960931,2
    C,F--43190582(+) CCTAAA/CGTGTT 1 -- us2k11Minor allele frequency- C:0.17EA 120
    rs1421760061,2
    --43190594(+) AGTAAC/TCTTTT 1 -- us2k10--------
    rs737510481,2
    C,F--43190645(+) TCTTTG/AGGGTG 1 -- us2k11Minor allele frequency- A:0.50WA 2
    rs353758731,2
    C,F--43190647(+) TTTGGG/CGTGTG 1 -- us2k13Minor allele frequency- C:0.18NA 124
    rs1926666901,2
    --43190702(+) TTTGAA/GGCTCT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for NIM1K (43192173 - 43280952 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for NIM1K: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NIM1K
    DNA2.0 Custom Variant and Variant Library Synthesis for NIM1K

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for NIM1K gene integrated from 10 sources:
    (articles sorted by number of sources associating them with NIM1K)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of the sucrose non-fermenting related kinase SNRK, as a novel LKB1 substrate. (PubMed id 15733851)1, 2, 3 Jaleel M....Alessi D.R. (FEBS Lett. 2005)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    5. Patterns of somatic mutation in human cancer genomes. (PubMed id 17344846)2 Greenman C.... Stratton M.R. (Nature 2007)
    6. The DNA sequence and comparative analysis of human chromosome 5. (PubMed id 15372022)2 Schmutz J.... Rubin E.M. (Nature 2004)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 167359 HGNC: 28646 AceView: MGC42105 Ensembl:ENSG00000177453 euGenes: HUgn167359
    ECgene: NIM1K H-InvDB: NIM1K

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
      --

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for NIM1K gene:
    Search GeneIP for patents involving NIM1K

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for NIM1K   OriGene RNAi products in human, mouse, rat for NIM1K  
     OriGene qPCR primer pairs and template standards for NIM1K   Browse OriGene Protein Over-expression Lysates  
     OriGene MassSpec for NIM1K   OriGene clones in human, mouse for NIM1K  
     OriGene qSTAR qPCR primer pairs in human, mouse for NIM1K   OriGene Purified Protein for NIM1K  
     OriGene ORF clones in mouse, rat for NIM1K   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for NIM1K   OriGene Custom Protein Services for NIM1K  

     
     
     Block miRNA regulation of human, mouse, rat NIM1K using miScript Target Protectors SeqTarget long-range PCR primers for resequencing NIM1K
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NIM1K Predesigned siRNA for gene silencing in human, mouse, rat NIM1K
     QuantiFast Probe-based Assays in human, mouse, rat NIM1K QuantiTect SYBR Green Assays in human, mouse, rat NIM1K
     Custom PCR Arrays for NIM1K Search Chromatin IP Primers for NIM1K
     Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat NIM1K Search GeneGlobe Interaction Network for NIM1K
     Search Regulatory tfbs for NIM1K
     GenScript Custom Purified and Recombinant Proteins Services for NIM1K GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for NIM1K
     GenScript Custom Assay Services for NIM1K GenScript Custom overexpressing Cell Line Services for NIM1K
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for NIM1K (NIM1)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     NIM1K antibodies
     NIM1K proteins
     NIM1K lysates
     Search for Antibodies for NIM1K at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for NIM1K
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.



     Browse ESI BIO Cell Lines and PureStem Progenitors for NIM1K
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NIM1K
     Browse SwitchGear 3'UTR luciferase reporter plasmids for NIM1K
     Browse SwitchGear Promoter luciferase reporter plasmids for NIM1K
     ThermoFisher Antibodies for NIM1K
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NIM1K
     Browse compounds at ApexBio
     Addgene plasmids for NIM1K
      Search eBioscience for proteins for NIM1K
      Search eBioscience for elisas for NIM1K
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for NIM1K
     antibodies-online antibodies for NIM1K (26 products)
     antibodies-online kits for NIM1K (2 products)
     antibodies-online peptides for NIM1K
     antibodies-online proteins for NIM1K (5 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      NIM1K gene at Home site.
    Version: 3.12.250 16 Nov 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4