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NIF3L1 Gene

protein-coding   GIFtS: 58
GCID: GC02P201718

NIF3 NGG1 Interacting Factor 3-Like 1 (S. Cerevisiae)

(Previous names: NIF3 (Ngg1 interacting factor 3, S.pombe homolog)-like 1,...)
(Previous symbol: ALS2CR1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
NIF3 NGG1 Interacting Factor 3-Like 1 (S. Cerevisiae)1 2     NIF3 NGG1 Interacting Factor 3-Like 1 (S. Pombe)1
ALS2CR11 2 3     CALS-72
NIF3 (Ngg1 Interacting Factor 3, S.Pombe Homolog)-Like 11 2     Amyotrophic Lateral Sclerosis 2 (Juvenile) Chromosome Region, Candidate 12
Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 1
Protein2 3
     Putative GTP Cyclohydrolase 1 Type 2 NIF3L12
GTP Cyclohydrolase I2 3     EC 3.5.4.163
NIF3-Like Protein 12 3     

External Ids:    HGNC: 133901   Entrez Gene: 604912   Ensembl: ENSG000001962907   OMIM: 6057785   UniProtKB: Q9GZT83   

Export aliases for NIF3L1 gene to outside databases

Previous GC identifers: GC02P199971 GC02P200478 GC02P201956 GC02P201579 GC02P201462 GC02P193605


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for NIF3L1 Gene:
NIF3L1 (NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)) is a protein-coding gene. Diseases associated with NIF3L1 include amyotrophic lateral sclerosis 2, juvenile, and lateral sclerosis. GO annotations related to this gene include transcription factor binding.

UniProtKB/Swiss-Prot: GTPC1_HUMAN, Q9GZT8
Function: Converts GTP to dihydroneopterin triphosphate (By similarity)

Gene Wiki entry for NIF3L1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000002.12  NT_005403.18  NC_018913.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the NIF3L1 gene promoter:
         PPAR-gamma1   SRY   AML1a   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNIF3L1 promoter sequence
   Search Chromatin IP Primers for NIF3L1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NIF3L1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q33   Ensembl cytogenetic band:  2q33.1   HGNC cytogenetic band: 2q33

NIF3L1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NIF3L1 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P201718:  view genomic region     (about GC identifiers)

Start:
201,754,050 bp from pter      End:
201,768,655 bp from pter
Size:
14,606 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: GTPC1_HUMAN, Q9GZT8 (See protein sequence)
Recommended Name: Putative GTP cyclohydrolase 1 type 2 NIF3L1  
Size: 377 amino acids; 41968 Da
Subunit: Homodimer. Interacts with COPS2 (By similarity). Interacts with THOC7
Sequence caution: Sequence=AAG14952.1; Type=Frameshift; Positions=104, 109;
Secondary accessions: Q53TX4 Q6X735 Q9H2D2 Q9HC18
Alternative splicing: 3 isoforms:  Q9GZT8-1   Q9GZT8-2   Q9GZT8-3   

Explore the universe of human proteins at neXtProt for NIF3L1: NX_Q9GZT8

Explore proteomics data for NIF3L1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys109, Lys216, Lys234, Lys242
  • Modification sites at PhosphoSitePlus

  • See NIF3L1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001129511.1  NP_001135827.1  NP_001135828.1  NP_068596.2  

    ENSEMBL proteins: 
     ENSP00000412761   ENSP00000394955   ENSP00000386394   ENSP00000352711   ENSP00000387315  
     ENSP00000387061   ENSP00000387021   ENSP00000399336   ENSP00000400787  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR017222 UCP037490_NIF3_euk
     IPR002678 Interacting_NIF3

    Graphical View of Domain Structure for InterPro Entry Q9GZT8

    ProtoNet protein and cluster: Q9GZT8

    1 Blocks protein domain: IPB002678 Protein of unknown function DUF34

    UniProtKB/Swiss-Prot: GTPC1_HUMAN, Q9GZT8
    Similarity: Belongs to the GTP cyclohydrolase I type 2 family


    NIF3L1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GTPC1_HUMAN, Q9GZT8
    Function: Converts GTP to dihydroneopterin triphosphate (By similarity)
    Catalytic activity: GTP + H(2)O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine
    triphosphate

         Enzyme Number (IUBMB): EC 3.5.4.161

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003934GTP cyclohydrolase I activity IEA--
    GO:0005515protein binding IPI16189514
    GO:0005525GTP binding IEA--
    GO:0008134transcription factor binding IPI15163635
    GO:0046872metal ion binding IEA--
         
    NIF3L1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for NIF3L1:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NIF3L1
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    GTPC1_HUMAN, Q9GZT8: Cytoplasm
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion3
    peroxisome2
    cytosol1
    nucleus1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA15163635
    GO:0005739mitochondrion IEA--

    NIF3L1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    UniProtKB/Swiss-Prot: GTPC1_HUMAN, Q9GZT8
    Pathway: Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate
    from GTP: step 1/1

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NIF3L1
    Interactions:

        Search GeneGlobe Interaction Network for NIF3L1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for NIF3L1 (Q9GZT81, 2, 3 ENSP000003863944) via UniProtKB, MINT, STRING, and/or I2D (see all 94)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    DHPSP493661, 2, 3, ENSP000002100604EBI-740897,EBI-741925 MINT-66223 I2D: score=5 STRING: ENSP00000210060
    CCDC85BQ158342, 3, ENSP000003116954MINT-66117 I2D: score=5 STRING: ENSP00000311695
    DMRTB1Q96MA12, 3, ENSP000003605004MINT-67776 I2D: score=5 STRING: ENSP00000360500
    KCTD17Q8N5Z52, 3, ENSP000003843914MINT-67014 I2D: score=5 STRING: ENSP00000384391
    KRT15P190122, 3, ENSP000002540434MINT-68114 I2D: score=5 STRING: ENSP00000254043
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:00359987,8-dihydroneopterin 3'-triphosphate biosynthetic process IEA--
    GO:0045893positive regulation of transcription, DNA-templated IDA15163635

    NIF3L1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NIF3L1 (GTPC1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for NIF3L1 gene (4 alternative transcripts): 
    NM_001136039.2  NM_001142355.1  NM_001142356.1  NM_021824.3  

    Unigene Cluster for NIF3L1:

    NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
    Hs.145284  [show with all ESTs]
    Unigene Representative Sequence: AK127110
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000426253 ENST00000454952 ENST00000409020(uc002uwn.2) ENST00000359683
    ENST00000409357 ENST00000409129 ENST00000409588 ENST00000436412 ENST00000416651(uc002uwm.2 uc002uwl.2 uc002uwp.2 uc002uwq.2)

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      QuantiTect SYBR Green Assays in human, mouse, rat NIF3L1
      QuantiFast Probe-based Assays in human, mouse, rat NIF3L1

    Additional mRNA sequence: 

    AB038949.1 AF060513.1 AF182416.1 AF283538.1 AK023378.1 AK125652.1 AK127110.1 AK225905.1 
    AK314709.1 AL834430.1 AY251943.1 AY251944.1 BC007654.2 

    16 DOTS entries:

    DT.100028392  DT.216841  DT.100812831  DT.100812830  DT.100812827  DT.120963386  DT.100812825  DT.120963511 
    DT.120963566  DT.40271297  DT.97788016  DT.120963470  DT.95195088  DT.100812829  DT.216843  DT.100783837 

    Selected AceView cDNA sequences (see all 304):

    BE503822 AA928143 BE797115 AF283538 BM841141 CA307646 BM557530 AI369270 
    AI686707 AA721176 AI382838 AA494361 AW024457 CR603298 AI340087 BC007654 
    BU688003 CR612823 CR620321 BQ010727 BM545164 BQ010660 AK023378 BM724212 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for NIF3L1 (see all 7)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8 ^ 9
    SP1:                    -     -                                                         
    SP2:                                                                                    
    SP3:                                                                                    
    SP4:                                                                    -               
    SP5:        -     -     -     -                                                         


    ECgene alternative splicing isoforms for NIF3L1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NIF3L1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGTCAGTGGG
    NIF3L1 Expression
    About this image

    NIF3L1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NIF3L1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.145284
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for NIF3L1 gene from Selected species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nif3l11 , 5 Ngg1 interacting factor 3-like 1 (S. pombe)1, 5 85.73(n)1
    84.57(a)1
      1 (29.10 cM)5
    651021  NM_022988.21  NP_075364.21 
     584451515 
    chicken
    (Gallus gallus)
    Aves NIF3L11 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) 71(n)
    71.75(a)
      424076  XM_421932.4  XP_421932.3 
    lizard
    (Anolis carolinensis)
    Reptilia NIF3L16
    NIF3 NGG1 interacting factor 3-like 1 (S. cerevisi...
    66(a)
    1 ↔ 1
    1(118137443-118145619)
    African clawed frog
    (Xenopus laevis)
    Amphibia BI449359.12   -- 73.04(n)    BI449359.1 
    zebrafish
    (Danio rerio)
    Actinopterygii nif3l11 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) 54.94(n)
    49.13(a)
      574421  NM_001029968.1  NP_001025139.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG42781 , 3 CG42781 41(a)3
    48.99(n)1
    45.3(a)1
      2 35F113
    349701  NM_135946.31  NP_609790.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes NIF3(YGL221C)4
    NIF31
    Protein of unknown function, similar to Listeria monocytogenes more4
    NIF31
    48.81(n)1
    40.59(a)1
      7(82292-81426)4
    8526511, 4  NP_011294.11, 4 


    ENSEMBL Gene Tree for NIF3L1 (if available)
    TreeFam Gene Tree for NIF3L1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NIF3L1 gene
    1 SIMAP similar gene for NIF3L1 using alignment to 6 protein entries:     GTPC1_HUMAN (see all proteins):
    DKFZp762L015

    NIF3L1 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for NIF3L1
    PGOHUM00000244372 PGOHUM00000233102


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NIF3L1 (see all 256)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1845475461,2
    --201755909(+) TCTTGA/GCTTTG 4 -- int1 us2k10--------
    rs1471785821,2
    --201755944(+) AAGTGC/TTGGGA 4 -- int1 us2k10--------
    rs1486315931,2
    --201755957(+) ACAGGC/TGCCCC 4 -- int1 us2k10--------
    rs1420781931,2
    --201756006(+) GCCAGC/TATATA 4 -- int1 us2k10--------
    rs1511334721,2
    C--201756057(+) GCAGTA/GTCATT 4 -- int1 us2k10--------
    rs1131095941,2
    C,F--201756251(+) GAGGGG/AGCTTG 4 -- int1 us2k12Minor allele frequency- A:0.03CSA WA 120
    rs1893691971,2
    --201756349(+) AGGCAA/GGAGAT 4 -- int1 us2k10--------
    rs752220081,2
    F--201756455(+) GTTTCG/ATAGGT 4 -- int1 us2k11Minor allele frequency- A:0.09WA 118
    rs1144310571,2
    F--201756554(+) ATGACG/AACAGC 4 -- int1 us2k11Minor allele frequency- A:0.03WA 118
    rs765782071,2
    C,F--201756653(+) AACTTT/CACCTG 4 -- ut51 int11Minor allele frequency- C:0.05WA 118

    HapMap Linkage Disequilibrium report for NIF3L1 (201754050 - 201768655 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for NIF3L1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv3109CNV Loss18451855

    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing NIF3L1
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 605778    OMIM disorders: --

    8 diseases for NIF3L1:    
    About MalaCards
    amyotrophic lateral sclerosis 2, juvenile    lateral sclerosis    amyotrophic lateral sclerosis    williams-beuren syndrome
    pneumonia    tuberculosis    ataxia    malaria

    1 disease from the University of Copenhagen DISEASES database for NIF3L1:
    Williams-Beuren syndrome

    NIF3L1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): NIF3L1
    Human Genome Epidemiology (HuGE) Navigator: NIF3L1 (1 document)

    Export disorders for NIF3L1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NIF3L1 gene, integrated from 10 sources (see all 23):
    (articles sorted by number of sources associating them with NIF3L1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Isolation and characterization of a novel human gene, NIF3L1, and its mouse ortholog, Nif3l1, highly conserved from bacteria to mammals. (PubMed id 11124544)1, 2, 3, 9 Tascou S....Burfeind P. (Cytogenet. Cell Genet. 2000)
    2. Cloning and characterization of three novel genes, ALS2CR1, ALS2CR2, and ALS2CR3, in the juvenile amyotrophic lateral sclerosis (ALS2) critical region at chromosome 2q33-q34: candidate genes for ALS2. (PubMed id 11161814)1, 2, 3 Hadano S.... Hayden M.R. (Genomics 2001)
    3. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. The role of transcriptional corepressor Nif3l1 in early stage of neural differentiation via cooperation with Trip15/CSN2. (PubMed id 12522100)1, 3 Akiyama H....Tashiro F. (J. Biol. Chem. 2003)
    7. Identification and characterization of NIF3L1 BP1, a novel cytoplasmic interaction partner of the NIF3L1 protein. (PubMed id 12951069)1, 2 Tascou S.... Burfeind P. (Biochem. Biophys. Res. Commun. 2003)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    9. A high-throughput approach for measuring temporal changes in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (Nat. Methods 2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 60491 HGNC: 13390 AceView: NIF3L1 Ensembl:ENSG00000196290 euGenes: HUgn60491
    ECgene: NIF3L1 H-InvDB: NIF3L1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for NIF3L1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NIF3L1 gene:
    Search GeneIP for patents involving NIF3L1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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