External Ids for NID1 Gene
Previous HGNC Symbols for NID1 Gene
Previous GeneCards Identifiers for NID1 Gene
This gene encodes a member of the nidogen family of basement membrane glycoproteins. The protein interacts with several other components of basement membranes, and may play a role in cell interactions with the extracellular matrix. [provided by RefSeq, Jul 2008]
GeneCards Summary for NID1 Gene
NID1 (Nidogen 1) is a Protein Coding gene. Diseases associated with NID1 include neuronal intestinal dysplasia and keratopathy. Among its related pathways are Degradation of the extracellular matrix and Cell adhesion_ECM remodeling. GO annotations related to this gene include calcium ion binding and laminin binding. An important paralog of this gene is LRP5L.
UniProtKB/Swiss-Prot for NID1 Gene
Sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin. Also binds to collagen IV and perlecan. It probably has a role in cell-extracellular matrix interactions.