Free for academic non-profit institutions. Other users need a Commercial license

Aliases for NHSL2 Gene

Aliases for NHSL2 Gene

  • NHS-Like 2 2 3

External Ids for NHSL2 Gene

Summaries for NHSL2 Gene

GeneCards Summary for NHSL2 Gene

NHSL2 (NHS-Like 2) is a Protein Coding gene. An important paralog of this gene is NHS.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NHSL2 Gene

Genomics for NHSL2 Gene

Genomic Location for NHSL2 Gene

Start:
71,911,088 bp from pter
End:
72,147,604 bp from pter
Size:
236,517 bases
Orientation:
Plus strand

Genomic View for NHSL2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for NHSL2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NHSL2 Gene

Regulatory Elements for NHSL2 Gene

Proteins for NHSL2 Gene

  • Protein details for NHSL2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5HYW2-NHSL2_HUMAN
    Recommended name:
    NHS-like protein 2
    Protein Accession:
    Q5HYW2
    Secondary Accessions:
    • B2RN94

    Protein attributes for NHSL2 Gene

    Size:
    709 amino acids
    Molecular mass:
    76301 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NHSL2 Gene

Proteomics data for NHSL2 Gene at MOPED

Post-translational modifications for NHSL2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for NHSL2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for NHSL2 Gene

Domains for NHSL2 Gene

Protein Domains for NHSL2 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

NHSL2_HUMAN
Family:
  • Belongs to the NHS family.:
    • Q5HYW2
genes like me logo Genes that share domains with NHSL2: view

No data available for Gene Families for NHSL2 Gene

Function for NHSL2 Gene

miRNA for NHSL2 Gene

miRTarBase miRNAs that target NHSL2

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for NHSL2 Gene

Localization for NHSL2 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for NHSL2 Gene COMPARTMENTS Subcellular localization image for NHSL2 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for NHSL2 Gene

Pathways for NHSL2 Gene

SuperPathways for NHSL2 Gene

No Data Available

Interacting Proteins for NHSL2 Gene

Gene Ontology (GO) - Biological Process for NHSL2 Gene

None

No data available for Pathways by source for NHSL2 Gene

Transcripts for NHSL2 Gene

mRNA/cDNA for NHSL2 Gene

(4) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(7) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for NHSL2 Gene

NHS-like 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for NHSL2 Gene

No ASD Table

Relevant External Links for NHSL2 Gene

GeneLoc Exon Structure for
NHSL2
ECgene alternative splicing isoforms for
NHSL2

Expression for NHSL2 Gene

mRNA expression in normal human tissues for NHSL2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for NHSL2 Gene

This gene is overexpressed in Whole Blood (12.1).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for NHSL2 Gene

SOURCE GeneReport for Unigene cluster for NHSL2 Gene Hs.397836

genes like me logo Genes that share expressions with NHSL2: view

Orthologs for NHSL2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for NHSL2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia NHSL2 36
  • 99.18 (n)
  • 99.18 (a)
NHSL2 37
  • 92 (a)
OneToOne
cow
(Bos Taurus)
Mammalia NHSL2 36
  • 90.2 (n)
  • 87.5 (a)
NHSL2 37
  • 85 (a)
OneToOne
dog
(Canis familiaris)
Mammalia NHSL2 36
  • 88.1 (n)
  • 85.05 (a)
NHSL2 37
  • 83 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Nhsl2 36
  • 86.49 (n)
  • 84.66 (a)
Nhsl2 16
Nhsl2 37
  • 84 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia NHSL2 37
  • 57 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 22 (a)
OneToMany
-- 37
  • 46 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Nhsl2 36
  • 84.86 (n)
  • 83.12 (a)
chicken
(Gallus gallus)
Aves -- 37
  • 52 (a)
OneToMany
-- 37
  • 3 (a)
OneToMany
NHSL2 36
  • 63.43 (n)
  • 59.02 (a)
lizard
(Anolis carolinensis)
Reptilia NHSL2 37
  • 45 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia nhsl2 36
  • 55.51 (n)
  • 50.17 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC794153 36
  • 51.96 (n)
  • 44.13 (a)
NHSL2 37
  • 25 (a)
OneToOne
Species with no ortholog for NHSL2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for NHSL2 Gene

ENSEMBL:
Gene Tree for NHSL2 (if available)
TreeFam:
Gene Tree for NHSL2 (if available)

Paralogs for NHSL2 Gene

Paralogs for NHSL2 Gene

genes like me logo Genes that share paralogs with NHSL2: view

Variants for NHSL2 Gene

Sequence variations from dbSNP and Humsavar for NHSL2 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs3936164 -- 72,085,111(+) TATTG(G/T)CCTCA intron-variant
rs4076908 -- 72,109,470(-) acaaa(C/T)aacaa intron-variant
rs4076909 -- 72,109,823(-) GCCAT(A/G)TAAAG intron-variant
rs4132935 -- 72,138,720(+) CACTT(C/T)CTGGA reference, missense
rs4986596 -- 71,978,261(-) TAAGG(A/T)GATGT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for NHSL2 Gene

Variant ID Type Subtype PubMed ID
dgv2451e1 CNV Complex 17122850
nsv517419 CNV Gain 19592680
nsv6956 CNV Loss 18451855
esv1106651 CNV Insertion 17803354
esv2740219 CNV Deletion 23290073
esv268632 CNV Insertion 20981092
nsv525711 CNV Gain 19592680

Relevant External Links for NHSL2 Gene

HapMap Linkage Disequilibrium report
NHSL2
Locus Specific Mutation Databases (LSDB)
NHSL2

Disorders for NHSL2 Gene

No disorders were found for NHSL2 Gene.

No data available for UniProtKB/Swiss-Prot for NHSL2 Gene

Publications for NHSL2 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 4
  5. A quantitative atlas of mitotic phosphorylation. (PMID: 18669648) Dephoure N. … Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008) 4

Products for NHSL2 Gene

Sources for NHSL2 Gene

Back to Top

Content