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Aliases for NHLRC4 Gene

Aliases for NHLRC4 Gene

  • NHL Repeat Containing 4 2 3

External Ids for NHLRC4 Gene

Previous GeneCards Identifiers for NHLRC4 Gene

  • GC16P000558
  • GC16P000612
  • GC16P000614

Summaries for NHLRC4 Gene

GeneCards Summary for NHLRC4 Gene

NHLRC4 (NHL Repeat Containing 4) is a Protein Coding gene. An important paralog of this gene is TRIM32.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NHLRC4 Gene

Genomics for NHLRC4 Gene

Genomic Location for NHLRC4 Gene

Start:
566,996 bp from pter
End:
569,495 bp from pter
Size:
2,500 bases
Orientation:
Plus strand

Genomic View for NHLRC4 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for NHLRC4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NHLRC4 Gene

No data available for Regulatory Elements for NHLRC4 Gene

Proteins for NHLRC4 Gene

  • Protein details for NHLRC4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0CG21-NHLC4_HUMAN
    Recommended name:
    NHL-repeat-containing protein 4
    Protein Accession:
    P0CG21
    Secondary Accessions:
    • B8ZZ27
    • Q8N233
    • Q96AX3
    • Q96S23

    Protein attributes for NHLRC4 Gene

    Size:
    123 amino acids
    Molecular mass:
    12631 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NHLRC4 Gene

Proteomics data for NHLRC4 Gene at MOPED

Post-translational modifications for NHLRC4 Gene

No Post-translational modifications

Other Protein References for NHLRC4 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for NHLRC4 Gene

Domains for NHLRC4 Gene

Protein Domains for NHLRC4 Gene

Suggested Antigen Peptide Sequences for NHLRC4 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P0CG21

UniProtKB/Swiss-Prot:

NHLC4_HUMAN :
  • P0CG21
Similarity:
  • Contains 2 NHL repeats.
genes like me logo Genes that share domains with NHLRC4: view

No data available for Gene Families for NHLRC4 Gene

Function for NHLRC4 Gene

Gene Ontology (GO) - Molecular Function for NHLRC4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with NHLRC4: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for NHLRC4

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for NHLRC4 Gene

Localization for NHLRC4 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for NHLRC4 Gene

Pathways for NHLRC4 Gene

SuperPathways for NHLRC4 Gene

No Data Available

Gene Ontology (GO) - Biological Process for NHLRC4 Gene

None

No data available for Pathways by source for NHLRC4 Gene

Transcripts for NHLRC4 Gene

mRNA/cDNA for NHLRC4 Gene

Unigene Clusters for NHLRC4 Gene

NHL repeat containing 4:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for NHLRC4

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for NHLRC4
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for NHLRC4 Gene

No ASD Table

Relevant External Links for NHLRC4 Gene

GeneLoc Exon Structure for
NHLRC4
ECgene alternative splicing isoforms for
NHLRC4

Expression for NHLRC4 Gene

mRNA expression in normal human tissues for NHLRC4 Gene

SOURCE GeneReport for Unigene cluster for NHLRC4 Gene Hs.664267

genes like me logo Genes that share expressions with NHLRC4: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for NHLRC4 Gene

Orthologs for NHLRC4 Gene

This gene was present in the common ancestor of chordates.

Orthologs for NHLRC4 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia LOC618053 35
  • 80.05 (n)
  • 77.05 (a)
NHLRC4 36
  • 68 (a)
OneToOne
dog
(Canis familiaris)
Mammalia NHLRC4 36
  • 64 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Nhlrc4 35
  • 79.67 (n)
  • 78.86 (a)
Nhlrc4 16
Nhlrc4 36
  • 70 (a)
OneToOne
chicken
(Gallus gallus)
Aves NHLRC4 36
  • 23 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia NHLRC4 36
  • 31 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101734263 35
  • 57.68 (n)
  • 55.65 (a)
Species with no ortholog for NHLRC4:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NHLRC4 Gene

ENSEMBL:
Gene Tree for NHLRC4 (if available)
TreeFam:
Gene Tree for NHLRC4 (if available)

Paralogs for NHLRC4 Gene

Paralogs for NHLRC4 Gene

genes like me logo Genes that share paralogs with NHLRC4: view

Variants for NHLRC4 Gene

Sequence variations from dbSNP and Humsavar for NHLRC4 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs3760050 -- 567,061(+) CCCAG(A/C)GAGAC utr-variant-5-prime
rs28678550 -- 566,196(+) AGGAG(A/G)AGCAG upstream-variant-2KB
rs34303355 -- 566,602(+) TCCTT(-/T)CGCTG upstream-variant-2KB
rs34832302 -- 566,271(+) CAGGG(-/G)AGATA upstream-variant-2KB
rs61433825 -- 567,924(+) GGCAC(C/T)TTCCT utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for NHLRC4 Gene

Variant ID Type Subtype PubMed ID
esv2422427 CNV Duplication 17116639
dgv2469n71 CNV Loss 21882294
nsv904707 CNV Loss 21882294
nsv528354 CNV Loss 19592680
nsv526903 CNV Loss 19592680
dgv2475n71 CNV Loss 21882294
dgv2476n71 CNV Loss 21882294
dgv2478n71 CNV Gain+Loss 21882294
dgv2479n71 CNV Loss 21882294
dgv2480n71 CNV Loss 21882294
nsv833113 CNV Loss 17160897
nsv833114 CNV Gain+Loss 17160897
dgv2481n71 CNV Loss 21882294
nsv471064 CNV Gain 18288195
nsv471063 CNV Loss 18288195
nsv904750 CNV Loss 21882294
dgv2483n71 CNV Loss 21882294
dgv2484n71 CNV Loss 21882294
dgv2485n71 CNV Loss 21882294
nsv457304 CNV Gain 19166990
dgv2486n71 CNV Loss 21882294

Relevant External Links for NHLRC4 Gene

HapMap Linkage Disequilibrium report
NHLRC4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NHLRC4 Gene

Disorders for NHLRC4 Gene

No disorders were found for NHLRC4 Gene.

No data available for UniProtKB/Swiss-Prot for NHLRC4 Gene

Publications for NHLRC4 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J. … Pennacchio L.A. (Nature 2004) 3 4

Products for NHLRC4 Gene

Sources for NHLRC4 Gene

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