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NHLRC3 Gene

protein-coding   GIFtS: 46
GCID: GC13P039612

NHL Repeat Containing 3

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
NHL Repeat Containing 31 2
NHL Repeat-Containing Protein 32

External Ids:    HGNC: 337511   Entrez Gene: 3879212   Ensembl: ENSG000001888117   UniProtKB: Q5JS373   

Export aliases for NHLRC3 gene to outside databases

Previous GC identifers: GC13P038512 GC13P020412


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for NHLRC3 Gene:
This gene encodes a protein containing NCL-1, HT2A and Lin-41 (NHL) family repeats. Mammalian NHL-repeat
containing proteins may be involved in a variety of enzymatic processes, including protein modification through
ubiquitination. Alternatively spliced transcript variants have been observed for this gene. (provided by RefSeq,
Aug 2012)

GeneCards Summary for NHLRC3 Gene:
NHLRC3 (NHL repeat containing 3) is a protein-coding gene.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000013.10  NC_018924.2  NT_024524.15  
Regulatory elements:
   Regulatory transcription factor binding sites in the NHLRC3 gene promoter:
         Nkx2-2   FOXO3   E47   FOXO3b   AREB6   SRY   HSF2   Hand1   FOXO3a   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNHLRC3 promoter sequence
   Search Chromatin IP Primers for NHLRC3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NHLRC3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q13.3   Ensembl cytogenetic band:  13q13.3   HGNC cytogenetic band: 13q13.3

NHLRC3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NHLRC3 gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13P039612:  view genomic region     (about GC identifiers)

Start:
39,612,443 bp from pter      End:
39,624,246 bp from pter
Size:
11,804 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: NHLC3_HUMAN, Q5JS37 (See protein sequence)
Recommended Name: NHL repeat-containing protein 3 precursor  
Size: 347 amino acids; 38283 Da
Secondary accessions: B2RTZ2 B4DTL0 Q69YI9
Alternative splicing: 2 isoforms:  Q5JS37-1   Q5JS37-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NHLRC3: NX_Q5JS37

Explore proteomics data for NHLRC3 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys86
  • Glycosylation2 at Asn32, Asn101, Asn206, Asn278
  • Modification sites at PhosphoSitePlus

  • See NHLRC3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001012772.1  NP_001017370.1  

    ENSEMBL proteins: 
     ENSP00000418127   ENSP00000368920   ENSP00000368919  

    NHLRC3 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for NHLRC3

     
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    LSBio Antibodies in human, mouse, rat for NHLRC3

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    Cloud-Clone Corp. ELISAs for NHLRC3
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    Search eBioscience for ELISAs for NHLRC3 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR011042 6-blade_b-propeller_TolB-like
     IPR013017 NHL_repeat_subgr
     IPR001258 NHL_repeat

    Graphical View of Domain Structure for InterPro Entry Q5JS37

    ProtoNet protein and cluster: Q5JS37

    UniProtKB/Swiss-Prot: NHLC3_HUMAN, Q5JS37
    Similarity: Contains 4 NHL repeats


    Find genes that share domains with NHLRC3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with NHLRC3           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for NHLRC3:
     Decreased TP53 protein express 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NHLRC3
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NHLRC3

    miRNA
    Products:
        
    miRTarBase miRNAs that target NHLRC3:
    hsa-mir-192-5p (MIRT026785), hsa-mir-93-5p (MIRT028124), hsa-mir-335-5p (MIRT018575), hsa-mir-16-5p (MIRT031913), hsa-mir-96-5p (MIRT027923), hsa-let-7d-5p (MIRT032166), hsa-mir-196a-5p (MIRT026034)

    Block miRNA regulation of human, mouse, rat NHLRC3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NHLRC3 (see all 47):
    hsa-miR-302d hsa-miR-520e hsa-miR-520f hsa-let-7d hsa-miR-106a hsa-miR-1258 hsa-let-7g hsa-miR-124
    SwitchGear 3'UTR luciferase reporter plasmidNHLRC3 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat NHLRC3

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector (see all 2): NHLRC3 (NM_001012754)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NHLRC3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NHLRC3

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NHLRC3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NHLC3_HUMAN, Q5JS37: Secreted (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular3
    lysosome2
    cytosol1
    endoplasmic reticulum1
    golgi apparatus1
    mitochondrion1
    plasma membrane1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--

    Find genes that share ontologies with NHLRC3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NHLRC3
    Interactions:

        Search GeneGlobe Interaction Network for NHLRC3

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for NHLRC3 (ENSP000003689204) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GTPBP1ENSP000002160444STRING: ENSP00000216044
    GTPBP2ENSP000003039974STRING: ENSP00000303997
    NR2E1ENSP000003579824STRING: ENSP00000357982
    --ENSP000003171994STRING: ENSP00000317199
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NHLRC3 (NHLC3)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for NHLRC3 gene (2 alternative transcripts): 
    NM_001012754.3  NM_001017370.2  

    Unigene Cluster for NHLRC3:

    NHL repeat containing 3
    Hs.507783  [show with all ESTs]
    Unigene Representative Sequence: NM_001012754
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000473371 ENST00000470258(uc001uxe.3) ENST00000379600(uc001uxc.3 uc001uxd.3)
    ENST00000379599 ENST00000485407
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat NHLRC3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NHLRC3 (see all 47):
    hsa-miR-302d hsa-miR-520e hsa-miR-520f hsa-let-7d hsa-miR-106a hsa-miR-1258 hsa-let-7g hsa-miR-124
    SwitchGear 3'UTR luciferase reporter plasmidNHLRC3 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for NHLRC3
    Predesigned siRNA for gene silencing in human, mouse, rat NHLRC3
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    GenScript: all cDNA clones in your preferred vector (see all 2): NHLRC3 (NM_001012754)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NHLRC3
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for NHLRC3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NHLRC3
      QuantiTect SYBR Green Assays in human, mouse, rat NHLRC3
      QuantiFast Probe-based Assays in human, mouse, rat NHLRC3

    Additional mRNA sequence: 

    AK299198.1 AK300260.1 BC052492.1 BC140877.1 BC140878.1 BX647872.1 BX648122.1 CR749318.1 
    NR_073109.1 

    9 DOTS entries:

    DT.101980575  DT.100645571  DT.121643807  DT.110938  DT.120786351  DT.97834901  DT.121608532  DT.92028625 
    DT.431850 

    Selected AceView cDNA sequences (see all 103):

    AW085909 BX371392 AA319240 CK904628 AA337222 BM068789 CK904627 AI276164 
    AI582629 CR613108 AA477704 AI655763 AL536880 AA052951 AA293021 AA464514 
    AA962570 CA397493 AA464515 CR601315 CR625961 AA457150 AL698460 AL833329 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for NHLRC3 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b ^ 5a · 5b · 5c ^ 6 ^ 7
    SP1:                                            -     -                 -     -               
    SP2:                    -                       -     -                 -     -               
    SP3:                                            -     -     -           -     -               
    SP4:                                                                                          
    SP5:                                            -     -                                       


    ECgene alternative splicing isoforms for NHLRC3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NHLRC3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    NHLRC3 Expression
    About this image

    NHLRC3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NHLRC3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.507783
        Custom PCR Arrays for NHLRC3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NHLRC3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for NHLRC3 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nhlrc31 , 5 NHL repeat containing 31, 5 83.19(n)1
    83.86(a)1
      3 (25.15 cM)5
    2121141  NM_172501.21  NP_766089.11 
     534485885 
    chicken
    (Gallus gallus)
    Aves NHLRC31 NHL repeat containing 3 68.62(n)
    65.74(a)
      418890  XM_417084.3  XP_417084.2 
    lizard
    (Anolis carolinensis)
    Reptilia NHLRC36
    NHL repeat containing 3
    61(a)
    1 ↔ 1
    1(132254778-132275012)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia nhlrc31 NHL repeat containing 3 63.85(n)
    59.52(a)
      100497010  XM_002936727.2  XP_002936773.1 
    zebrafish
    (Danio rerio)
    Actinopterygii NHLRC36
    NHL repeat containing 3
    53(a)
    1 ↔ 1
    10(31560-35379) ENSDARG00000088063


    ENSEMBL Gene Tree for NHLRC3 (if available)
    TreeFam Gene Tree for NHLRC3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NHLRC3 gene
    1 SIMAP similar gene for NHLRC3 using alignment to 2 protein entries:     NHLC3_HUMAN (see all proteins):
    DKFZp313A0825

    Find genes that share paralogs with NHLRC3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NHLRC3 (see all 216)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 13 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1874317551,2
    C--39614281(+) GATCGC/TGCCAC 3 -- int10--------
    rs1905989661,2
    C--39614327(+) CTCAAA/GAAAAA 3 -- int10--------
    rs1500423231,2
    C--39614338(+) AAAAAA/GAAAGA 3 -- int10--------
    rs124289491,2
    C,H--39614350(+) AGAAAT/GTTGAC 3 -- int15Minor allele frequency- G:0.09NA WA EA 362
    rs1829361791,2
    --39614443(+) AATAAC/TTCTAA 3 -- int10--------
    rs753483711,2
    C,F--39614628(+) CATGTC/GTGAAA 3 -- int11Minor allele frequency- G:0.09WA 118
    rs1141508711,2
    F--39614683(+) AAGTGA/CGCACA 3 -- int11Minor allele frequency- C:0.04WA 118
    rs792762631,2
    C,F--39614824(+) ATTATT/CTCTAG 3 -- int11Minor allele frequency- C:0.07NA 120
    rs18871111,2
    C,F,A,H--39614863(-) ATGTCT/CCTCAA 3 -- int121Minor allele frequency- C:0.47MN NA EA NS WA CSA 1179
    rs1853314871,2
    --39614970(+) AACCCA/GTAAGA 3 -- int10--------

    HapMap Linkage Disequilibrium report for NHLRC3 (39612443 - 39624246 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for NHLRC3: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NHLRC3
    DNA2.0 Custom Variant and Variant Library Synthesis for NHLRC3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with NHLRC3           About GenesLikeMe

    Genetic Association Database (GAD): NHLRC3

    Export disorders for NHLRC3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NHLRC3 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with NHLRC3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    2. A genome-wide association for kidney function and endocrine-related traits in the NHLBI's Framingham Heart Study. (PubMed id 17903292)4 Hwang S.J....Fox C.S. (BMC Med. Genet. 2007)
    3. Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study. (PubMed id 17903301)4 Vasan R.S....Benjamin E.J. (BMC Med. Genet. 2007)
    4. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    6. The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)2 Dunham A.... Ross M.T. (Nature 2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 387921 HGNC: 33751 AceView: LOC387921 Ensembl:ENSG00000188811 euGenes: HUgn387921
    ECgene: NHLRC3 H-InvDB: NHLRC3

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NHLRC3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NHLRC3 gene:
    Search GeneIP for patents involving NHLRC3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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