NGLY1 Gene
protein-coding GIFtS: 56
GCID: GC03M025735
|
|
N-glycanase 1
| |
Aliases
for NGLY1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| N-Glycanase 11 2 3 | | FLJ110051 | | PNG11 2 3 5 | | Peptide-N(4)-(N-Acetyl-Beta-Glucosaminyl)Asparagine Amidase2 | | PNGase2 3 | | Peptide:N-Glycanase1 | | HPNGase1 | | Peptide:N-Glycanase1 | | EC 3.5.1.523 8 | | |
Export aliases for NGLY1 gene to outside databasesPrevious GC identifers: GC03M025468 GC03M025610 |
Summaries
for NGLY1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for NGLY1:
This gene encodes an enzyme that catalyzes hydrolysis of an N(4)-(acetyl-beta-D-glucosaminyl) asparagine residue toN-acetyl-beta-D-glucosaminylamine and a peptide containing an aspartate residue. The encoded enzyme may play a role inthe proteasome-mediated degradation of misfolded glycoproteins. Multiple transcript variants encoding differentisoforms have been found for this gene.(provided by RefSeq, Feb 2009)
UniProtKB/Swiss-Prot: NGLY1_HUMAN, Q96IV0Function: Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists theirproteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chainof Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex typeoligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to bedestroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisitefor subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins
Gene Wiki entry for NGLY1
|
Genomic Views
for NGLY1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_022517.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the NGLY1 gene promoter:
NF-1 NF-1/L RelA NF-kappaB NF-kappaB1 FOXL1 Roaz
Other transcription factors
Search SABiosciences Chromatin IP Primers for NGLY1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NGLY1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3p24.2 Ensembl cytogenetic band: 3p24.2 HGNC cytogenetic band: 3p23NGLY1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03M025735: view genomic region
(about GC identifiers)
Start:
|
25,760,435 bp from pter |
End:
|
25,831,530 bp from pter |
Size:
|
71,096 bases |
Orientation:
|
minus strand |
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Proteins
for NGLY1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NGLY1_HUMAN, Q96IV0 (See
protein sequence)Recommended Name: Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase Size: 654 amino acids; 74390 Da
Cofactor: Binds 1 zinc ion per subunit (By similarity)
Subunit: Component of a complex required to couple retrotranslocation, ubiquitination and deglycosylation composed ofNGLY1, SAKS1, AMFR, VCP and RAD23B. Interacts with the proteasome components RAD23B and PSMC1. Interacts with directlywith VCP. Interacts with DERL1, bringing it close to the endoplasmic reticulum membrane. Interacts with SAKS1
Subcellular location: Cytoplasm
Miscellaneous: In case of infection by cytomegaloviruses, it is not essential for degradation of MHC class I heavychains
Sequence caution: Sequence=AAH17220.1; Type=Erroneous termination; Positions=77; Note=Translated as Glu;Sequence=BAD92786.1; Type=Erroneous initiation;
2 PDB 3D structures from  and Proteopedia  for NGLY1:2CCQ (3D)
2CM0 (3D)
Secondary accessions: B4DJE9 Q59FB1 Q6PJD8 Q9BVR8 Q9NR70Alternative splicing: 5 isoforms: Q96IV0-1 Q96IV0-2 Q96IV0-3 Q96IV0-4 Q96IV0-5 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for NGLY1: NX_Q96IV0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96IV0
4/15 DME Specific Peptides for NGLY1 (Q96IV0) (see all 15)
NGLY1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001138765.1 NP_001138766.1 NP_001138767.1 NP_060767.2
ENSEMBL proteins: ENSP00000280700 ENSP00000379886 ENSP00000307980 ENSP00000280699 ENSP00000389888 ENSP00000412946 ENSP00000387430 ENSP00000395878
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table
NGLY1 for ontologies About GeneDecksing
NGLY1 Antibody Products:
Assay Products for NGLY1: |
Protein
Domains /
Families
for NGLY1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NGLY1 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q96IV0ProtoNet protein and cluster: Q96IV0 UniProtKB/Swiss-Prot: NGLY1_HUMAN, Q96IV0Domain: The PUB domain mediates the interaction with VCPSimilarity: Belongs to the transglutaminase-like superfamily. PNGase familySimilarity: Contains 1 PAW domainSimilarity: Contains 1 PUB (PUG) domain |
Function
for NGLY1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: NGLY1_HUMAN, Q96IV0Function: Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists theirproteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chainof Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex typeoligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to bedestroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisitefor subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteinsCatalytic activity: Hydrolysis of an N(4)-(acetyl-beta-D-glucosaminyl)asparagine residue in which the glucosamineresidue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and a peptidecontaining an aspartate residueEnzyme regulation: Inhibited by Z-VAD-fmk, a well-known caspase inhibitor, which inhibits enzyme activity throughcovalent binding of the carbohydrate to the single Cys-306 residueEnzyme Number (IUBMB): EC 3.5.1.521 2
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NGLY1 (see all 5)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for NGLY1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NGLY1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NGLY1 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000224 | peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity |
IEA | -- | | GO:0005515 | protein binding |
IPI | 15358861 | | GO:0046872 | metal ion binding |
IEA | -- |
NGLY1 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for NGLY1:
|
Pathways & Interactions
for NGLY1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Protein processing in endoplasmic reticulum | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Kegg Pathway (Kegg details for NGLY1):
NGLY1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NGLY1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 16)
5/20 Interacting proteins for NGLY1 (Q96IV02, 3 ENSP000002807004) via UniProtKB, MINT, STRING, and/or I2D (see all 20)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006516 | glycoprotein catabolic process |
IDA | 15358861 |
NGLY1 for ontologies About GeneDecksing
|
Drugs & Compounds
for NGLY1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for NGLY1
1 HMDB Compound for NGLY1 About this table
Search CenterWatch for drugs/clinical trials and news about NGLY1
|
Transcripts
for NGLY1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for NGLY1 gene (5 alternative transcripts): NM_001145293.1 NM_001145294.1 NM_001145295.1 NM_018297.3 NM_025105.1 Unigene Cluster for NGLY1: N-glycanase 1 Hs.743367 [show with all ESTs]Unigene Representative Sequence: NM_01829716 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000489271 ENST00000280700 ENST00000493324 ENST00000396649 ENST00000467224
ENST00000308710 ENST00000496726 ENST00000280699 ENST00000417874 ENST00000427041
ENST00000461491 ENST00000474611 ENST00000478991 ENST00000463611 ENST00000428257(uc003cdk.3 uc003cdl.3 uc010hfg.3 uc003cdm.3 uc011awo.2)
ENST00000422724
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NGLY1 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NGLY1 (see all 5)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 4): NGLY1 (NM_001145293) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NGLY1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NGLY1 |
Additional cDNA sequence: AB114414.1 AB114415.1 AF250924.2 AK001867.1 AK296047.1 AL832748.1 BC000963.2 BC007226.1 BC017220.2 14 DOTS entries: DT.100796715 DT.100026099 DT.443708 DT.120928011 DT.100026100 DT.435466 DT.120927972 DT.120928006 DT.413873 DT.91741227 DT.91741228 DT.75135381 DT.95239822 DT.99985830 24/194 AceView cDNA sequences (see all 194): CR617659 AA625702 BC007226 CR611129 CB160600 CA412944 BM142576 BQ230989 BU616528 BQ017148 BM803678 AI985596 BI827140 BU620630 AI144268 CA418577 AI743962 AI200902 BU158405 BQ219031 AF250924 BU680543 AW072945 BE408444
GeneLoc Exon Structure
5/13 Alternative Splicing Database (ASD) splice patterns (SP) for NGLY1 (see all 13) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | · | 2d | · | 2e | ^ | 3 | ^ | 4a | · | 4b | · | 4c | · | 4d | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b | · | 10c | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15a | · |
|---|
|
| SP1: | | | | | | | | | | | - | | - | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | - | | |
| SP2: | | | | | | | | | | | - | | - | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | - | | | | | | - | | |
| SP3: | | | | | | | | | | | - | | - | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | - | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | - | | | | | | | | - | | - | | | | | | | | - | | |
| SP5: | | | | | | | | | | | - | | - | | | | | | | | - | | - | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | |
| ExUns: | 15b | ^ | 16 | ^ | 17a | · | 17b | · | 17c |
|---|
|
| SP1: | | | | | | | | | | | |
| SP2: | | | | | | | | | | | |
| SP3: | | | - | | | | | | | | |
| SP4: | | | | | | | | | | | |
| SP5: | | | | | | | | | | |
ECgene alternative splicing isoforms for NGLY1
|
Expression
for NGLY1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NGLY1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAAATTATCT
About this image
See NGLY1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NGLY1
SOURCE GeneReport for Unigene cluster: Hs.743367
SABiosciences Custom PCR Arrays for NGLY1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NGLY1
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NGLY1 |
Orthologs
for NGLY1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for NGLY1 gene from 10/33 species (see all 33) About this table
ENSEMBL Gene Tree for NGLY1 (if available)
TreeFam Gene Tree for NGLY1 (if available) |
Paralogs
for NGLY1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for NGLY1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for NGLY1 (25760435 - 25831530 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for NGLY1: --
Human Gene Mutation Database (HGMD): NGLY1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NGLY1 |
|
Disorders
/ Diseases
for NGLY1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 NGLY1 for disorders About MalaCards
NGLY1 for disorders About GeneDecksing
OMIM gene information: 610661
OMIM disorders: --
Human Genome Epidemiology (HuGE) Navigator: NGLY1 (2 documents)
Export disorders for NGLY1 gene to outside databases
|
Publications
for NGLY1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NGLY1 gene, integrated from 9 sources (see all 23):
(articles sorted by number of sources associating them with NGLY1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A glycosylated type I membrane protein becomes cytosolic when peptide: N-glycanase is compromised. (PubMed id 14749736)1, 2, 9 Blom D.... Ploegh H.L. (2004)
- The PUB domain functions as a p97 binding module in human peptide N- glycanase. (PubMed id 16807242)1, 2 Allen M.D.... Bycroft M. (2006)
- The retrotranslocation protein derlin-1 binds peptide:N-glycanase to the endoplasmic reticulum. (PubMed id 16055502)1, 2 Katiyar S.... Lennarz W.J. (2005)
- A novel UBA and UBX domain protein that binds polyubiquitin and VCP and is a substrate for SAPKs. (PubMed id 15362974)1, 2 McNeill H.... Cohen P. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- A complex between peptide:N-glycanase and two proteasome-linked proteins suggests a mechanism for the degradation of misfolded glycoproteins. (PubMed id 15358861)1, 2 Katiyar S.... Lennarz W.J. (2004)
- Using a small molecule inhibitor of peptide: N-glycanase to probe its role in glycoprotein turnover. (PubMed id 15610852)1, 2 Misaghi S.... Korbel G.A. (2004)
- PNG1, a yeast gene encoding a highly conserved peptide:N-glycanase. (PubMed id 10831608)1, 2 Suzuki T.... Lennarz W.J. (2000)
- Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 Jager S....Krogan N.J. (2012)
|
External Searches for NGLY1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing NGLY1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NGLY1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NGLY1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for NGLY1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for NGLY1 gene:
Search GeneIP for patents involving NGLY1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for NGLY1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for NGLY1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NGLY1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NGLY1 | | | OriGene Protein Over-expression Lysate for NGLY1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for NGLY1 | | OriGene 3'-UTR Clone for NGLY1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NGLY1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NGLY1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for NGLY1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for NGLY1 | | OriGene Custom Protein Services for NGLY1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NGLY1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NGLY1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NGLY1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NGLY1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NGLY1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NGLY1 |
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| | | | Search Tocris compounds for NGLY1 |
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 | | | NGLY1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NGLY1 |
|  |  |  | | | | ThermoFisher Antibody for NGLY1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NGLY1 |
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