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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NGFRAP1 Gene

protein-coding   GIFtS: 57
GCID: GC0XP102631

nerve growth factor receptor (TNFRSF16) associated protein...
 Explore 3 diseases affiliated with
NGFRAP1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for NGFRAP1    

Aliases
for NGFRAP1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Nerve Growth Factor Receptor (TNFRSF16) Associated Protein 11 2     Nerve Growth Factor Receptor-Associated Protein 12 3
BEX31 2 3 5     Ovarian Granulosa Cell 13.0 KDa Protein HGR742 3
DXS6984E1 2 3 5     P75NTR-Associated Cell Death Executor2 3
NADE1 2 3 5     Brain Expressed, X-Linked 32
Bex1 2     Ovarian Granulosa Cell Protein (13kD)2
HGR741 2     Protein BEX32
Brain-Expressed X-Linked Protein 32 3     

External Ids:    HGNC: 133881   Entrez Gene: 270182   Ensembl: ENSG000001666817   OMIM: 3003615   UniProtKB: Q009943   

Export aliases for NGFRAP1 gene to outside databases

Previous GC identifers: GC0XP097933 GC0XP099540 GC0XP100664 GC0XP101403 GC0XP102437 GC0XP092293


Summaries
for NGFRAP1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: BEX3_HUMAN, Q00994
Function: May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in
zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases

Gene Wiki entry for NGFRAP1


Genomic Views
for NGFRAP1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_018934.1  NT_011651.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NGFRAP1 gene promoter:
         MZF-1   HOXA3   POU3F2 (N-Oct-5b)   POU3F2 (N-Oct-5a)   POU3F2   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): NGFRAP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for NGFRAP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NGFRAP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq22.2   Ensembl cytogenetic band:  Xq22.2   HGNC cytogenetic band: Xq22.2

NGFRAP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NGFRAP1 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP102631:  view genomic region     (about GC identifiers)

Start:
 102,631,268 bp from pter      End:
 102,633,005 bp from pter
Size:
 1,738 bases      Orientation:
 plus strand

Proteins
for NGFRAP1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: BEX3_HUMAN, Q00994 (See protein sequence)
Recommended Name: Protein BEX3  
Size: 111 amino acids; 12959 Da
Subunit: Self-associates. Interacts with 14-3-3 epsilon (YWHAE). Interacts with DIABLO/SMAC (By similarity). Binds to
the DEATH domain of p75NTR/NGFR
Subcellular location: Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm and the nucleus. Associates with
replicating mitochondria (By similarity)
Miscellaneous: Binds transition metals (By similarity)
Sequence caution: Sequence=CAI41523.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for NGFRAP1:
1SA6 (3D)    
Secondary accessions: B2RD17 D3DXA3 Q5JQT4 Q5JQT5

Explore the universe of human proteins at neXtProt for NGFRAP1: NX_Q00994

Post-translational modifications:

  • Ubiquitinated. Degraded by the proteasome (By similarity)1
  • View neXtProt modification sites for NX_Q00994

    • NGFRAP1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_055195.1  NP_996798.1  NP_996800.1  

    ENSEMBL proteins: 
     ENSP00000354843   ENSP00000361728   ENSP00000361718   ENSP00000361717   ENSP00000299872  
    Reactome Protein details: Q00994
    Human Recombinant Protein Products: 
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    Novus Biologicals NGFRAP1 Proteins
    Novus Biologicals NGFRAP1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for NGFRAP1

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IDA--
    GO:0005829cytosol TAS--


    NGFRAP1 for ontologies           About GeneDecksing



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    ThermoFisher Antibodies for NGFRAP1

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    Uscn ELISAs and CLIAs for NGFRAP1

    Protein Domains /
    Families
    for NGFRAP1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    NGFRAP1 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR021156 TF_A-like/BEX-like
     IPR007623 BEX

    Graphical View of Domain Structure for InterPro Entry Q00994

    ProtoNet protein and cluster: Q00994

    UniProtKB/Swiss-Prot: BEX3_HUMAN, Q00994
    Domain: The nuclear export signal is required for export from the nucleus and the interactions with itself and
    p75NTR/NGFR (By similarity)
    Similarity: Belongs to the BEX family


    Function
    for NGFRAP1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: BEX3_HUMAN, Q00994
    Function: May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in
    zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases

    miRNA
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    hsa-miR-3910 hsa-miR-196a* hsa-miR-513a-5p hsa-miR-27a hsa-miR-3120-3p hsa-miR-128 hsa-miR-3681* hsa-miR-545
    SwitchGear 3'UTR luciferase reporter plasmid: NGFRAP1 3' UTR sequence
    Inhib. RNA
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    OriGene shRNA RFP: NGFRAP1
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NGFRAP1

    Gene Editing
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    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for NGFRAP1

    In Situ Assay
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         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NGFRAP1

    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005123death receptor binding IEA--
    GO:0005515protein binding IPI17355907
    GO:0008656cysteine-type endopeptidase activator activity involved in apoptotic process TAS--
    GO:0046872metal ion binding IEA--


    NGFRAP1 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for NGFRAP1:
     Downregulation of NF-kappaB pa  Downregulation of NF-kappaB pa 


    Pathways & Interactions
    for NGFRAP1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/8 super-pathways (see all 8) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Cell death signalling via NRAGE, NRIF and NADE
    		Cell death signalling via NRAGE, NRIF and NADE1.00
    		p75 NTR receptor-mediated signalling0.73
    2Apoptosis and survival_Apoptotic TNF-family pathways
    		Apoptosis and survival_Apoptotic TNF-family pathways1.00
    		Apoptosis and survival Apoptotic TNF-family pathways1.00
    3NADE modulates death signalling
    		NADE modulates death signalling1.00
    414-3-3 and Regulation of BAD Activity
    		14-3-3 and Regulation of BAD Activity1.00
    5p75(NTR)-mediated signaling
    		p75(NTR)-mediated signaling1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for NGFRAP1
        Apoptosis and survival Apoptotic TNF-family pathways

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for NGFRAP1
        14-3-3 and Regulation of BAD Activity

    1 GeneGo (Thomson Reuters) Pathway for NGFRAP1
        Apoptosis and survival Apoptotic TNF-family pathways

    1 BioSystems Pathway for NGFRAP1 
        p75(NTR)-mediated signaling

    5        Reactome Pathways for NGFRAP1
        Cell death signalling via NRAGE, NRIF and NADE
    Signal Transduction
    Signalling by NGF
    NADE modulates death signalling
    p75 NTR receptor-mediated signalling


    1         Kegg Pathway  (Kegg details for NGFRAP1):
        Neurotrophin signaling pathway


    NGFRAP1 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NGFRAP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/32 Interacting proteins for NGFRAP1 (Q009941, 2, 3 ENSP000003617184) via UniProtKB, MINT, STRING, and/or I2D (see all 32)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCDC85BQ158342, 3, ENSP000003116954MINT-66193 I2D: score=5 STRING: ENSP00000311695
    TSC1Q925741, 3, ENSP000002985524EBI-741753,EBI-1386638 I2D: score=3 STRING: ENSP00000298552
    NGFRP081383, ENSP000001722294I2D: score=3 STRING: ENSP00000172229
    YWHAEP622583, ENSP000002643354I2D: score=2 STRING: ENSP00000264335
    TRAF5O004633, ENSP000002614644I2D: score=1 STRING: ENSP00000261464
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006915apoptotic process TAS--
    GO:0006917induction of apoptosis IEA--
    GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process TAS--
    GO:0007275multicellular organismal development TAS2171551
    GO:0008625extrinsic apoptotic signaling pathway via death domain receptors IEA--


    NGFRAP1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for NGFRAP1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NGFRAP1
    Search CenterWatch for drugs/clinical trials and news about NGFRAP1 / BEX3 

    Transcripts
    for NGFRAP1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for NGFRAP1 gene (3 alternative transcripts): 
    NM_014380.1  NM_206915.1  NM_206917.1  

    Unigene Cluster for NGFRAP1:

    Nerve growth factor receptor (TNFRSF16) associated protein 1
    Hs.448588  [show with all ESTs]
    Unigene Representative Sequence: BC051713
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000361298(uc004eki.3 uc004ekh.3) ENST00000372645 ENST00000372635
    ENST00000372634 ENST00000299872(uc004ekj.1)

    miRNA
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    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate NGFRAP1 (see all 13):
    hsa-miR-3910 hsa-miR-196a* hsa-miR-513a-5p hsa-miR-27a hsa-miR-3120-3p hsa-miR-128 hsa-miR-3681* hsa-miR-545
    SwitchGear 3'UTR luciferase reporter plasmid: NGFRAP1 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NGFRAP1 (see all 7)
    OriGene shRNA RFP: NGFRAP1
    OriGene siRNA: NGFRAP1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NGFRAP1
    Clone
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    GenScript: all cDNA clones in your preferred vector (see all 3): NGFRAP1 (NM_206915)
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    Primer
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    Additional cDNA sequence: 

    AF187064.1 AK057859.1 AK315371.1 AY833562.1 BC003190.1 BC051713.1 M38188.1 

    15 DOTS entries:

    DT.100687029  DT.92449185  DT.101957151  DT.101985280  DT.92449177  DT.100876587  DT.100687009  DT.121282459 
    DT.121282466  DT.102831833  DT.121282455  DT.92449186  DT.95372052  DT.121282450  DT.121282471 

    24/601 AceView cDNA sequences (see all 601):

    BQ436076 BF316261 AI859419 BC003190 BU949889 AW002096 BQ068114 AA513724 
    CA434910 AW160845 BE378166 BM662614 BM705100 BU581619 BP379155 CA848589 
    CA771425 BM974408 BU735527 BM985004 CD251390 M38188 BU581349 BU629261 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for NGFRAP1    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b · 3c
    SP1:                              
    SP2:              -               


    ECgene alternative splicing isoforms for NGFRAP1

    Expression
    for NGFRAP1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NGFRAP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GAAAAATTTA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    NGFRAP1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Definitive endoderm-like cells (A scalable, suspensi...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See NGFRAP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NGFRAP1

    SOURCE GeneReport for Unigene cluster: Hs.448588

    UniProtKB/Swiss-Prot: BEX3_HUMAN, Q00994
    Tissue specificity: Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also
    detected in liver

        SABiosciences Expression via Pathway-Focused PCR Arrays including NGFRAP1: 
              Neurotrophins & Receptors in human mouse rat
              TNF Ligands & Receptors in human mouse rat
              Necrosis in human mouse rat

    Primer
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NGFRAP1

    Orthologs
    for NGFRAP1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of human and mouse.

    Orthologs for NGFRAP1 gene from 1/5 species (see all 5)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Ngfrap11 , 5 nerve growth factor receptor (TNFRSF16) associated more1, 5 88.89(n)1
    92.79(a)1    		   X (57.64 cM)5
    120701  NM_009750.21  NP_033880.11 
     1362702615 


    ENSEMBL Gene Tree for NGFRAP1 (if available)
    TreeFam Gene Tree for NGFRAP1 (if available) 

    Paralogs
    for NGFRAP1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NGFRAP1 gene
    BEX12  BEX52  BEX22  BEX42  
    4 SIMAP similar genes for NGFRAP1 using alignment to 2 protein entries:     BEX3_HUMAN (see all proteins):
    BEX4    BEX5    BEX1    BEX2

    NGFRAP1 for paralogs           About GeneDecksing



    Genomic Variants
    for NGFRAP1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/50 NCBI SNPs in NGFRAP1 are shown (see all 50)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr X posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1491398931,2
    		--102629332(+) TCTGGC/TTTAGC 2 -- us2k10--------
    rs66164651,2
    		C,--102629402(+) GCTTGC/TCTTGC 2 -- us2k10--------
    rs1864935551,2
    		--102629565(+) CACTCA/GGGATA 2 -- us2k10--------
    rs1465219821,2
    		--102629997(+) ATCGCA/GCCACT 2 -- us2k10--------
    rs346783491,2
    		C--102630003(+) CACTG-/CACTCC 2 -- us2k10--------
    rs1920979391,2
    		--102630381(+) GAGCCA/GCCATG 3 -- us2k10--------
    rs2016744041,2
    		--102630445(+) GATGT-/TGTGTGT 3 -- us2k10--------
    rs1839716371,2
    		--102630483(+) TACAGA/GTCAAC 3 -- us2k10--------
    rs1885162931,2
    		--102630698(+) ACCACA/GCCCAG 3 -- us2k10--------
    rs1931714161,2
    		--102630735(+) GGGGTC/TTCACC 3 -- us2k10--------

    HapMap Linkage Disequilibrium report for NGFRAP1 (102631268 - 102633005 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for NGFRAP1
         1 CNV: 96862

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    Disorders / Diseases
    for NGFRAP1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    NGFRAP1 for disorders           About GeneDecksing

    OMIM gene information: 300361    OMIM disorders: --

    3 diseases for NGFRAP1:    About MalaCards
    aicardi syndrome    prostatitis    neuronitis


    Export disorders for NGFRAP1 gene to outside databases

    Publications
    for NGFRAP1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NGFRAP1 gene, integrated from 9 sources (see all 23):
    (articles sorted by number of sources associating them with NGFRAP1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. NADE, a p75NTR-associated cell death executor, is involved in signal transduction mediated by the common neurotrophin receptor p75NTR. (PubMed id 10764727)1, 2, 3, 9 Mukai J.... Sato T.-A. (2000)
    2. Characterization of three abundant mRNAs from human ovarian granulosa cells. (PubMed id 2171551)1, 2, 3 Rapp G....Scheit K.H. (1990)
    3. Characterization of the Bex gene family in humans, mice, and rats. (PubMed id 15958283)1, 2, 9 Alvarez E.... Freed C.R. (2005)
    4. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. NADE (p75NTR-associated cell death executor) suppresses cellular growth in vivo. (PubMed id 12739005)1, 9 Tong X....Koeffler H.P. (2003)
    7. Direct interaction of Smac with NADE promotes TRAIL-induced apoptosis. (PubMed id 15178455)1, 9 Yoon K....Lee S.Y. (2004)
    8. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    9. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    10. The TSC1 gene product hamartin interacts with NADE. (PubMed id 17355907)1 Yasui S....Ohno K. (2007)

    External Searches for NGFRAP1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing NGFRAP1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 27018 HGNC: 13388 AceView: NGFRAP1 Ensembl:ENSG00000166681 euGenes: HUgn27018
    ECgene: NGFRAP1 Kegg: 27018 H-InvDB: NGFRAP1

    Other Databases showing NGFRAP1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing NGFRAP1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NGFRAP1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for NGFRAP1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for NGFRAP1 gene:
    Search GeneIP for patents involving NGFRAP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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