NFX1 Gene
protein-coding GIFtS: 49
GCID: GC09P033280
|
|
nuclear transcription factor, X-box binding 1
| |
Aliases for NFX1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Nuclear Transcription Factor, X-Box Binding 11 2 | | NFX21 2 3 | | Nuclear Transcription Factor, X Box-Binding Protein 12 3 | | MGC203691 | | Transcriptional Repressor NF-X12 | | EC 6.3.2.-3 |
Export aliases for NFX1 gene to outside databasesPrevious GC identifers: GC09P033602 GC09P033459 |
Summaries for NFX1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for NFX1: MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind tothe X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encodedby this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHCclass II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response bylimiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, eachof which encodes a different isoform, have been identified. (provided by RefSeq, Jul 2008) UniProtKB/Swiss-Prot: NFX1_HUMAN, Q12986Function: Binds to the X-box motif of MHC class II genes and represses their expression. May play an important role inregulating the duration of an inflammatory response by limiting the period in which MHC class II molecules are inducedby interferon-gamma. Isoform 3 binds to the X-box motif of TERT promoter and represses its expression. Together withPABPC1 or PABPC4, isoform 1 acts as a coactivator for TERT expression. Mediates E2-dependent ubiquitination Gene Wiki entry for NFX1
|
Genomic Views for NFX1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000009.11 NC_018920.1 NT_008413.18
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the NFX1 gene promoter: Max1 AP-1 p53 ATF-2 STAT3 c-Jun LCR-F1 c-Ets-1 c-Myc Other transcription factors
Search SABiosciences Chromatin IP Primers for NFX1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NFX1 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9p13.3 Ensembl cytogenetic band: 9p13.3 HGNC cytogenetic band: 9p12NFX1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09P033280: view genomic region
(about GC identifiers)
Start:
|
33,290,418 bp from pter |
End:
|
33,371,155 bp from pter |
Size:
|
80,738 bases |
Orientation:
|
plus strand |
|
Proteins for NFX1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: NFX1_HUMAN, Q12986 (See
protein sequence)Recommended Name: Transcriptional repressor NF-X1 Size: 1120 amino acids; 124395 Da
Subunit: Isoform 1 and isoform 3 interact with human papillomavirus (HPV) type-16 E6 oncoprotein. Isoform 1 interactswith PABPC1 and PABPC4
Subcellular location: Nucleus
Sequence caution: Sequence=AAA69517.1; Type=Frameshift; Positions=78, 202, 284;
Secondary accessions: A8K6H8 Q5VXW6 Q96EL5 Q9BXI1Alternative splicing: 3 isoforms: Q12986-1 Q12986-2 Q12986-3 Explore the universe of human proteins at neXtProt for NFX1: NX_Q12986
Post-translational modifications:
Isoform 3 is polyubiquitinated in the presence of HPV16 E6 protein; which leads to proteasomal degradation. Isoform 1is not polyubiquitinated1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q12986 NFX1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_002495.2 NP_667344.1 NP_667345.1 ENSEMBL proteins: ENSP00000368856 ENSP00000368836 ENSP00000317695 Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
NFX1 for ontologies About GeneDecksing
NFX1 Antibody Products: Assay Products for NFX1: |
Protein
Domains / Families for NFX1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NFX1 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q12986ProtoNet protein and cluster: Q12986 4 Blocks protein families: IPB000967 Zn-finger IPB001374 Single-stranded nucleic acid binding R3H IPB001841 Zn-finger IPB001965 Zn-finger-like
UniProtKB/Swiss-Prot: NFX1_HUMAN, Q12986Domain: The RING-type zinc finger domain interacts with an ubiquitin-conjugating enzyme (E2) and facilitatesubiquitinationSimilarity: Belongs to the NFX1 familySimilarity: Contains 8 NF-X1-type zinc fingersSimilarity: Contains 1 R3H domainSimilarity: Contains 1 RING-type zinc finger |
Function for NFX1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: NFX1_HUMAN, Q12986Function: Binds to the X-box motif of MHC class II genes and represses their expression. May play an important role inregulating the duration of an inflammatory response by limiting the period in which MHC class II molecules are inducedby interferon-gamma. Isoform 3 binds to the X-box motif of TERT promoter and represses its expression. Together withPABPC1 or PABPC4, isoform 1 acts as a coactivator for TERT expression. Mediates E2-dependent ubiquitinationInduction: By IFNG/IFN-gammaEnzyme Number (IUBMB): EC 6.3.2.-1
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NFX1 (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NFX1 (see all 4) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): NFX1 (NM_147133) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NFX1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NFX1  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NFX1 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
NFX1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for NFX1:
|
Pathways & Interactions for NFX1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NFX1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/162 Interacting proteins for NFX1 (Q129863 ENSP000003688564) via UniProtKB, MINT, STRING, and/or I2D (see all 162)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000122 | negative regulation of transcription from RNA polymerase II promoter |
IEA | -- | | GO:0006366 | transcription from RNA polymerase II promoter |
TAS | 7964459 | | GO:0006954 | inflammatory response |
TAS | 7964459 | | GO:0019048 | virus-host interaction |
IEA | -- | | GO:0044419 | interspecies interaction between organisms |
-- | -- |
NFX1 for ontologies About GeneDecksing
|
Drugs & Compounds for NFX1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for NFX1 Search CenterWatch for drugs/clinical trials and news about NFX1 
|
Transcripts for NFX1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for NFX1 gene (3 alternative transcripts): NM_002504.4 NM_147133.2 NM_147134.2 Unigene Cluster for NFX1: Nuclear transcription factor, X-box binding 1 Hs.413074 [show with all ESTs]Unigene Representative Sequence: NM_0025046 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000379540(uc003zsq.3 uc003zsr.3) ENST00000379521(uc003zsp.2 uc010mjr.2) ENST00000318524(uc011lnw.2 uc003zso.3) ENST00000466359 ENST00000466971 ENST00000463421
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NFX1 (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NFX1 (see all 4) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): NFX1 (NM_147133) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NFX1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NFX1  |
Additional cDNA sequence: AF332009.1 AK225750.1 AK291643.1 AL832342.1 BC006447.1 BC012151.1 BX647337.1 U15306.1 19 DOTS entries: DT.100025546 DT.40214270 DT.100788161 DT.121187724 DT.100788160 DT.121187931 DT.100788168 DT.428516 DT.91651161 DT.121187722 DT.95083728 DT.421634 DT.86859957 DT.91969783 DT.95132329 DT.95132367 DT.121187752 DT.95093835 DT.95132366 24/288 AceView cDNA sequences (see all 288): BX647337 BQ894378 BC012151 AA905447 BQ434879 AA604553 AI301976 AI468184 BU428857 AI696922 CD515331 BU620169 AW302497 BM693697 AI287776 BU187330 AI871178 AI360004 BF516408 AI421926 AW731785 NM_147133 BE693262 BI091592 GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for NFX1 (see all 9) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | · | 13c | ^ | 14 | ^ | 15a | · | 15b | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for NFX1
|
Expression for NFX1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NFX1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: --
About this image See NFX1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for NFX1
SOURCE GeneReport for Unigene cluster: Hs.413074 SABiosciences Expression via Pathway-Focused PCR Arrays including NFX1:
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NFX1 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NFX1 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NFX1 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NFX1 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NFX1 |
Orthologs for NFX1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for NFX1 gene from 9/30 species (see all 30) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
NFX11 |
nuclear transcription factor, X-box binding 1 |
66.55(n) 62.36(a) |
  |
420796 XM_418890.3 XP_418890.3 |
lizard (Anolis carolinensis) |
Reptilia |
-- |
-- |
48(a) |
1 ↔ 1 |
4(66805308-66835896) |
tropical clawed frog (Xenopus tropicalis) |
Amphibia |
Str.182562 |
Transcribed sequence with moderate similarity to protein more |
77.69(n) |
  |
BX758948.1 |
zebrafish (Danio rerio) |
Actinopterygii |
Dr.160862 |
Transcribed sequence with weak similarity to protein more |
76.87(n) |
  |
BM860330.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
stc1 , 3 |
neurogenesis RNA polymerase II transcription factor3 shuttle craft1 |
43(a) (best of 2)3 48.96(n)1 43(a)1 |
  |
35C23 348881 NM_057250.31 NP_476598.11 |
worm (Caenorhabditis elegans) |
Secernentea |
C16A3.73 nfx-11 |
human NFX1\; D. melanogaster shuttle craft protein3 Protein NFX-11 |
40(a)3 47.57(n)1 40.45(a)1 |
  |
III(6447153-6450771)3 1759021 NM_065993.51 NP_498394.11 |
baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes |
FAP11 |
Fap1p |
46.85(n) 37.5(a) |
  |
855708 NP_014375.1 |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
NFXL11 |
NF-X1-type zinc finger protein NFXL1 |
45.95(n) 39.86(a) |
  |
837555 NM_100891.2 NP_172488.1 |
rice (Oryza sativa) |
Liliopsida |
Os06g02523001 |
hypothetical protein |
47.43(n) 43.46(a) |
  |
4340659 NM_001063833.1 NP_001057298.1 |
ENSEMBL Gene Tree for NFX1 (if available) TreeFam Gene Tree for NFX1 (if available)  |
Paralogs for NFX1 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for NFX1 gene
- NFXL12
NFX1 for paralogs About GeneDecksing
|
Genomic Variants for NFX1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 9 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for NFX1 (33290418 - 33371155 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for NFX1: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NFX1 |
|
Disorders
/ Diseases for NFX1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NFX1 for disorders About GeneDecksing
OMIM gene information: 603255
OMIM disorders: --
3 diseases for NFX1: About MalaCardsimmunodeficiency malaria neuronitis Export disorders for NFX1 gene to outside databases
|
Publications for NFX1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NFX1 gene, integrated from 9 sources (see all 30): (articles sorted by number of sources associating them with NFX1) | |  | Utopia: connect your pdf to the dynamic world of online information |
- A novel cysteine-rich sequence-specific DNA-binding protein interacts with the conserved X-box motif of the human major histocompatibility complex class II genes via a repeated Cys-His domain and functions as a transcriptional repressor. (PubMed id 7964459)1, 2, 3, 9 Song Z.... Ono S.J. (1994)
- NFX1-123 and poly(A) binding proteins synergistically augment activation of telomerase in human papillomavirus type 16 E6-expressing cells. (PubMed id 17267499)1, 2 Katzenellenbogen R.A....Galloway D.A. (2007)
- Identification of a novel telomerase repressor that interacts with the human papillomavirus type-16 E6/E6-AP complex. (PubMed id 15371341)1, 2 Gewin L.... Galloway D.A. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination. (PubMed id 10500182)1, 2 Lorick K.L....Weissman A.M. (1999)
- Congenital immunodeficiencies associated with absence of HLA class II antigens on lymphocytes result from distinct mutations in trans-acting factors. (PubMed id 2511169)1, 3 Hume C.R. and Lee J.S. (1989)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
- NFX1 plays a role in human papillomavirus type 16 E6 activation of NFkappaB activity. (PubMed id 20739528)1 Xu M....Galloway D.A. (2010)
|
External Searches for NFX1 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing NFX1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NFX1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NFX1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for NFX1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for NFX1 gene: Search GeneIP for patents involving NFX1
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for NFX1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for NFX1 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NFX1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NFX1 | | OriGene Protein Over-expression Lysate for NFX1 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for NFX1 | | OriGene 3'-UTR Clone for NFX1 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NFX1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NFX1 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for NFX1 | | OriGene Custom Protein Services for NFX1 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NFX1 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NFX1 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NFX1 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NFX1 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NFX1 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NFX1 |
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| | | Search Tocris compounds for NFX1 |
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 | | NFX1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NFX1 |
|  |  |  | | | Search ThermoFisher Antibodies for NFX1 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NFX1 |
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