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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NFKBIL1 Gene

protein-coding   GIFtS: 52
GCID: GC06P031514

Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer...


(Previous symbol: NFKBIL)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells
Inhibitor-Like 11 2 3
     LST12
NFKBIL1 2     ikappaBL2
Inhibitor Of Kappa B-Like Protein2 3     NF-Kappa-B Inhibitor-Like Protein 12
IKBL2 3     IkappaBL3
I-Kappa-B-Like Protein2 3     

External Ids:    HGNC: 78001   Entrez Gene: 47952   Ensembl: ENSG000002044987   OMIM: 6010225   UniProtKB: Q9UBC13   

Export aliases for NFKBIL1 gene to outside databases

Previous GC identifers: GC06P031578 GC06P031285 GC06P031619 GC06P031623


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NFKBIL1 Gene:
This gene encodes a divergent member of the I-kappa-B family of proteins. Its function has not been determined.
The gene lies within the major histocompatibility complex (MHC) class I region on chromosome 6. Multiple
transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Jan 2009)

GeneCards Summary for NFKBIL1 Gene: 
NFKBIL1 (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1) is a protein-coding gene. Diseases associated with NFKBIL1 include chronic thromboembolic pulmonary hypertension, and chronic venous leg ulcers. GO annotations related to this gene include protein binding.

UniProtKB/Swiss-Prot: IKBL1_HUMAN, Q9UBC1
Function: Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor
and interferon-regulatory factor (IRF) signaling pathways. Contributes to the negative regulation of
transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli

Gene Wiki entry for NFKBIL1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.2  NT_007592.15  NT_113891.2  NT_167245.1  NT_167246.1  NT_167247.1  NT_167248.1  
NT_167249.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NFKBIL1 gene promoter:
         HOXA5   ATF-2   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNFKBIL1 promoter sequence
   Search SABiosciences Chromatin IP Primers for NFKBIL1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NFKBIL1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.3   Ensembl cytogenetic band:  6p21.33   HGNC cytogenetic band: 6p21.3

NFKBIL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NFKBIL1 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P031514:  view genomic region     (about GC identifiers)

Start:
31,514,628 bp from pter      End:
31,526,606 bp from pter
Size:
11,979 bases      Orientation:
plus strand

6 alternative locations:
Chr6+,NT_167245 2,800,202-2,812,171      Chr6+,NT_167247 2,894,371-2,906,339      Chr6+,NT_167246 2,857,520-2,869,496     
Chr6+,NT_113891.2 3,024,283-3,036,248      Chr6+,NT_167248 2,808,299-2,820,269      Chr6+,NT_167249 2,845,433-2,857,408     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: IKBL1_HUMAN, Q9UBC1 (See protein sequence)
Recommended Name: NF-kappa-B inhibitor-like protein 1  
Size: 381 amino acids; 43204 Da
Subunit: Interacts with CACTIN (via N-terminus domain); the interaction occurs in a proinflammatory-independent
manner
Subcellular location: Nucleus. Note=Nuclear localization with a speckled expression pattern in some cells.
Colocalizes with CACTIN in the nucleus
Sequence caution: Sequence=BAG62473.1; Type=Erroneous termination; Positions=255; Note=Translated as Glu;
Secondary accessions: A6NL91 B4DUW1 Q14625 Q5HYU4 Q5RJ72 Q5ST96 Q5STV4 Q5STV5 Q9UBX4
Alternative splicing: 3 isoforms:  Q9UBC1-1   Q9UBC1-2   Q9UBC1-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NFKBIL1: NX_Q9UBC1

Explore proteomics data for NFKBIL1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9UBC1

  • NFKBIL1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NFKBIL1 Protein Expression
    REFSEQ proteins (4 alternative transcripts): 
    NP_001138433.1  NP_001138434.1  NP_001138435.1  NP_004998.3  

    ENSEMBL proteins: 
     ENSP00000365316   ENSP00000365318   ENSP00000365315   ENSP00000437148  

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    Browse Sino Biological Cell Lysates 
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    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005829cytosol IEA--

    NFKBIL1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR002110 Ankyrin_rpt
     IPR020683 Ankyrin_rpt-contain_dom

    Graphical View of Domain Structure for InterPro Entry Q9UBC1

    ProtoNet protein and cluster: Q9UBC1

    UniProtKB/Swiss-Prot: IKBL1_HUMAN, Q9UBC1
    Similarity: Contains 2 ANK repeats


    NFKBIL1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: IKBL1_HUMAN, Q9UBC1
    Function: Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor
    and interferon-regulatory factor (IRF) signaling pathways. Contributes to the negative regulation of
    transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli

         Genatlas biochemistry entry for NFKBIL1:
    nuclear transcription factor of kappa light chain gene enhancer in B cells (NF-kappa B) inhibitor ar,like
    1,sequestering it in the cytoplasm,also inhibiting NF-kappa B DNA binding

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    NFKBIL1 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI phenotypic allele for Nfkbil1 (no phenotypes)

    NFKBIL1 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for NFKBIL1 
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NFKBIL1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    5/22 Interacting proteins for NFKBIL1 (Q9UBC13 ENSP000003653184) via UniProtKB, MINT, STRING, and/or I2D (see all 22)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000233813Q9Y6763, ENSP000003984944I2D: score=2 STRING: ENSP00000398494
    ENSG00000203624Q9Y6763I2D: score=2 
    ENSG00000223775Q9Y6763I2D: score=2 
    ENSG00000226111Q9Y6763I2D: score=2 
    ENSG00000227420Q9Y6763I2D: score=2 
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007249I-kappaB kinase/NF-kappaB cascade IEA--
    GO:0031665negative regulation of lipopolysaccharide-mediated signaling pathway IDA--
    GO:0032088negative regulation of NF-kappaB transcription factor activity IDA--
    GO:0032720negative regulation of tumor necrosis factor production IMP--
    GO:0034122negative regulation of toll-like receptor signaling pathway IDA--

    NFKBIL1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NFKBIL1 (IKBL1)

    Search CenterWatch for drugs/clinical trials and news about NFKBIL1 / IKBL1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NFKBIL1 gene (4 alternative transcripts): 
    NM_001144961.1  NM_001144962.1  NM_001144963.1  NM_005007.3  

    Unigene Cluster for NFKBIL1:

    Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
    Hs.2764  [show with all ESTs]
    Unigene Representative Sequence: BM559803
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000376146(uc011dnr.2 uc011dns.2 uc011dnt.1) ENST00000376148(uc003nuc.3 uc003nub.3)
    ENST00000376145 ENST00000496233 ENST00000473655
    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidNFKBIL1 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NFKBIL1
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    Additional mRNA sequence: 

    AF097419.1 AF097420.1 AF097421.1 AF097422.1 AF097423.1 AF097424.1 AF097425.1 AF097426.1 
    AF097427.1 AF097428.1 AF097429.1 AK291893.1 AK300818.1 AK313888.1 BC105064.1 BC105068.1 
    BC143671.1 X77909.1 

    6 DOTS entries:

    DT.406878  DT.121310213  DT.100025757  DT.100703797  DT.86849562  DT.95101746 

    24/116 AceView cDNA sequences (see all 116):

    AF097422 AF097423 BM708717 AF097424 AF097420 CR624850 BM783544 AF097421 
    BM700433 AI359441 NM_005007 BE501839 AU143330 AF097419 AU104697 AI439090 
    CR593167 AA603457 AI925883 CR590712 CR601219 AU099198 AF097429 AW386957 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NFKBIL1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGAGGCCCT
    NFKBIL1 Expression
    About this image


    See NFKBIL1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NFKBIL1

    SOURCE GeneReport for Unigene cluster: Hs.2764

    UniProtKB/Swiss-Prot: IKBL1_HUMAN, Q9UBC1
    Tissue specificity: Detected in different cell types including monocytes, T-cells, B-cells and hepatocytes

        SABiosciences Expression via Pathway-Focused PCR Array including NFKBIL1: 
              Toll-Like Receptor Signaling Pathway in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NFKBIL1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for NFKBIL1 gene from 3/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nfkbil11 , 5 nuclear factor of kappa light polypeptide gene enhancer more1, 5 88.51(n)1
    92.37(a)1
      17 (18.60 cM)5
    180381  NM_010909.41  NP_035039.11 
     352201755 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    43(a)
    43(a)
    many → 1
    many → 1
    2(195780266-195786107)
    AAWZ02040396(79-5482)
    zebrafish
    (Danio rerio)
    Actinopterygii nfkbil16
    nuclear factor of kappa light polypeptide gene enh...
    33(a)
    1 ↔ 1
    10(7065847-7070301)


    ENSEMBL Gene Tree for NFKBIL1 (if available)
    TreeFam Gene Tree for NFKBIL1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/412 SNPs in NFKBIL1 are shown (see all 412)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs126617691,2
    H--31308932(+) aaaaaA/Gaaaaa 4 -- int1 trp30--------
    rs20715941,2
    C,F,A,H--31429675(-) TAGCAC/GAGTTC 2 -- us2k123Minor allele frequency- G:0.43NS EA NA WA CSA 2488
    rs1453289061,2
    --31429717(+) CAACCC/TTCACA 2 -- us2k10--------
    rs1425109321,2
    --31429736(+) ATTATC/TATCAT 2 -- us2k10--------
    rs20715931,2
    C,F,H--31429754(-) CTCCTC/TTGTGA 2 -- us2k128Minor allele frequency- T:0.12EA NA NS WA 4398
    rs1828987301,2
    --31429769(+) TCGAGC/GCTACC 2 -- us2k10--------
    rs455293391,2
    C,F--31429891(+) TATTAC/TAAATT 2 -- us2k11Minor allele frequency- T:0.06NA 120
    rs1163391191,2
    C,F--31429998(+) TAAGTG/ATCACA 2 -- us2k11Minor allele frequency- A:0.01WA 118
    rs1469092861,2
    C--31430106(+) GGAGGC/GAACTG 2 -- us2k10--------
    rs1465795491,2
    C--31430154(+) AATCCG/AGTAGT 2 -- us2k11Minor allele frequency- A:0.00NA 4510

    HapMap Linkage Disequilibrium report for NFKBIL1 (31514628 - 31526606 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for NFKBIL1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv830627CNV Loss17160897
    nsv884417CNV Loss21882294
    nsv470809CNV Loss18288195
    nsv884418CNV Gain21882294
    esv690CNV CNV17122850
    essv13266CNV CNV17122850


    Human Gene Mutation Database (HGMD): NFKBIL1
    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 601022   
    OMIM disorders: 180300  
    UniProtKB/Swiss-Prot: IKBL1_HUMAN, Q9UBC1
  • Rheumatoid arthritis (RA) [MIM:180300]: An inflammatory disease with autoimmune features and a complex
    genetic component. It primarily affects the joints and is characterized by inflammatory changes in the synovial
    membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal
    tissues, and by atrophy and rarefaction of bony structures. Note=Disease susceptibility is associated with
    variations affecting the gene represented in this entry

  • 20/28 diseases for NFKBIL1 (see all 28):    About MalaCards
    chronic thromboembolic pulmonary hypertension    chronic venous leg ulcers    autoimmune pancreatitis    juvenile rheumatoid arthritis
    deep vein thrombosis    autoimmune hepatitis    obsessive-compulsive disorder    rheumatoid arthritis
    thrombosis    sjogren's syndrome    graves' disease    dilated cardiomyopathy
    thromboembolism    ulcerative colitis    arthritis    systemic lupus erythematosus
    type 1 diabetes    hypertension    myocardial infarction    hepatitis c


    NFKBIL1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): NFKBIL1
    Human Genome Epidemiology (HuGE) Navigator: NFKBIL1 (36 documents)

    Export disorders for NFKBIL1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NFKBIL1 gene, integrated from 9 sources (see all 60):
    (articles sorted by number of sources associating them with NFKBIL1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of a novel gene in the human major histocompatibility complex that encodes a potential new member of the I kappa B family of proteins. (PubMed id 8081366)1, 2, 3 Albertella M.R. and Campbell D.R. (1994)
    2. IKBL promoter polymorphism is strongly associated with resistance to type 1 diabetes in Japanese. (PubMed id 14989711)1, 4, 9 Yamashita T....Yoshimatsu H. (2004)
    3. HLA-DPB1 and NFKBIL1 may confer the susceptibility to chronic thromboembolic pulmonary hypertension in the absence of deep vein thrombosis. (PubMed id 19165231)1, 4, 9 Kominami S....Kimura A. (2009)
    4. Association study between the -62A/T NFKBIL1 polymorp hism and obsessive-compulsive disorder. (PubMed id 19578685)1, 4, 9 Cordeiro Q....Hounie A.G. (2009)
    5. Haplotype analysis of a 100 kb region spanning TNF-LTA identifies a polymorphism in the LTA promoter region that is associated with atopic asthma susceptibility in Japan. (PubMed id 15969671)1, 4, 9 Migita O....Arinami T. (2005)
    6. Characterization of tumor necrosis factor-I+ block hap lotypes associated with susceptibility to chronic venous leg ulcers in Caucasia n patients. (PubMed id 20854863)1, 4 Tan J.H....Wallace H.J. (2010)
    7. Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection. (PubMed id 20587610)1, 4 Ucisik-Akkaya E....Tevfik Dorak M. (2010)
    8. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    9. [Association study between exon 4 NFKBIL1 polymorphis m and multiple sclerosis] (PubMed id 20568399)1, 4 Owecki M.K....Kozubski W. (2010)
    10. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 4795 HGNC: 7800 AceView: NFKBIL1 Ensembl:ENSG00000204498 euGenes: HUgn4795
    ECgene: NFKBIL1 H-InvDB: NFKBIL1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NFKBIL1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NFKBIL1 gene:
    Search GeneIP for patents involving NFKBIL1

    GeneCards and IP:
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