Aliases for NFIC Gene
External Ids for NFIC Gene
Previous Symbols for NFIC Gene
The protein encoded by this gene belongs to the CTF/NF-I family. These are dimeric DNA-binding proteins, and function as cellular transcription factors and as replication factors for adenovirus DNA replication. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
GeneCards Summary for NFIC Gene
NFIC (Nuclear Factor I/C (CCAAT-Binding Transcription Factor)) is a Protein Coding gene. Diseases associated with NFIC include common wart. Among its related pathways are Gene Expression and FOXA1 transcription factor network. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is NFIX.
UniProtKB/Swiss-Prot for NFIC Gene
Recognizes and binds the palindromic sequence 5-TTGGCNNNNNGCCAA-3 present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication