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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NFIB Gene

protein-coding   GIFtS: 61
GCID: GC09M014077

Nuclear Factor I/B

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Nuclear Factor I/B1 2 3     TGGCA-Binding Protein2 3
Nuclear Factor 1/B2 3     HMGIC/NFIB2
CTF2 3     NFI-RED2
NF-I/B2 3     NFIB22
NF1-B2 3     NFIB32
NFI-B2 3     Nuclear Factor 1 B-Type2
CCAAT-Box-Binding Transcription Factor2 3     

External Ids:    HGNC: 77851   Entrez Gene: 47812   Ensembl: ENSG000001478627   OMIM: 6007285   UniProtKB: O007123   

Export aliases for NFIB gene to outside databases

Previous GC identifers: GC09M014252 GC09M014068


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for NFIB Gene: 
NFIB (nuclear factor I/B) is a protein-coding gene. Diseases associated with NFIB include lipoma of colon, and polymorphous low-grade adenocarcinoma. GO annotations related to this gene include RNA polymerase II transcription corepressor activity and sequence-specific DNA binding RNA polymerase II transcription factor activity. An important paralog of this gene is NFIC.

UniProtKB/Swiss-Prot: NFIB_HUMAN, O00712
Function: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular
promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of
activating transcription and replication

Gene Wiki entry for NFIB Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NT_008413.18  NC_018920.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NFIB gene promoter:
         GR   COMP1   GR-beta   ARP-1   CUTL1   STAT5A   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNFIB promoter sequence
   Search SABiosciences Chromatin IP Primers for NFIB

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NFIB


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9p24.1   Ensembl cytogenetic band:  9p22.3   HGNC cytogenetic band: 9p24.1

NFIB Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NFIB gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M014077:  view genomic region     (about GC identifiers)

Start:
14,081,842 bp from pter      End:
14,398,982 bp from pter
Size:
317,141 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NFIB_HUMAN, O00712 (See protein sequence)
Recommended Name: Nuclear factor 1 B-type  
Size: 420 amino acids; 47442 Da
Subunit: Binds DNA as a homodimer
Subcellular location: Nucleus
Secondary accessions: H7BYE8 O00166 Q12858 Q5VW29 Q6ZNF9 Q96J45
Alternative splicing: 5 isoforms:  O00712-1   O00712-3   O00712-2   O00712-4   O00712-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NFIB: NX_O00712

Explore proteomics data for NFIB at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O00712

  • NFIB Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NFIB Protein Expression
    REFSEQ proteins (4 alternative transcripts): 
    NP_001177666.1  NP_001177667.1  NP_001269716.1  NP_005587.2  

    ENSEMBL proteins: 
     ENSP00000370346   ENSP00000370340   ENSP00000380705   ENSP00000380711   ENSP00000380709  
     ENSP00000370311   ENSP00000370308   ENSP00000475362   ENSP00000475813   ENSP00000442888  
     ENSP00000370321  

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    Browse Sino Biological Cell Lysates 
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    Cloud-Clone Corp. Proteins for NFIB 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IDA--
    GO:0005730nucleolus IDA--
    GO:0044300cerebellar mossy fiber ISS--

    NFIB for ontologies           About GeneDecksing



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    Cloud-Clone Corp. CLIAs for NFIB


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    5 InterPro protein domains:
     IPR000647 CTF/NFI
     IPR019548 CTF/NFI_DNA-bd_N
     IPR019739 CTF/NFI_DNA-bd_CS
     IPR003619 MAD_homology1_Dwarfin-type
     IPR020604 CTF/NFI_DNA-bd-dom

    Graphical View of Domain Structure for InterPro Entry O00712

    ProtoNet protein and cluster: O00712

    1 Blocks protein domain: IPB000647 CTF/NF-I family

    UniProtKB/Swiss-Prot: NFIB_HUMAN, O00712
    Similarity: Belongs to the CTF/NF-I family
    Similarity: Contains 1 CTF/NF-I DNA-binding domain


    NFIB for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NFIB_HUMAN, O00712
    Function: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular
    promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of
    activating transcription and replication

         Genatlas biochemistry entry for NFIB:
    nuclear transcription factor I B,DNA binding protein

         Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000981sequence-specific DNA binding RNA polymerase II transcription factor activity IDA19540848
    GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription IEA--
    GO:0001106RNA polymerase II transcription corepressor activity IDA9099724
    GO:0003677NOT DNA binding IDA9099724
    GO:0003700sequence-specific DNA binding transcription factor activity ----
         
    NFIB for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for NFIB:
     G0/1 arrest  Increased G1 DNA content 

         7 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Nfib):
     craniofacial  growth/size  homeostasis/metabolism  mortality/aging  nervous system 
     respiratory system  vision/eye 

    NFIB for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Nfibtm1Rmg for NFIB

       inGenious Targeting Laboratory - Custom generated mouse model solutions for NFIB 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for NFIB

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NFIB 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NFIB 

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NFIB


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for NFIB About                                                                                                See pathways by source

    SuperPathContained pathways About
    1FOXA1 transcription factor network
    FOXA1 transcription factor network


    1 BioSystems Pathway for NFIB
        FOXA1 transcription factor network


    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NFIB

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    5/6 Interacting proteins for NFIB (O007123 ENSP000003703464) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NFICP086513, ENSP000003968434I2D: score=2 STRING: ENSP00000396843
    NFIXQ149383, ENSP000003532194I2D: score=3 STRING: ENSP00000353219
    RFX1P226703, ENSP000002543254I2D: score=2 STRING: ENSP00000254325
    SOX2ENSP000003235884STRING: ENSP00000323588
    SUMO1ENSP000003760764STRING: ENSP00000376076
    About this table

    Gene Ontology (GO): 5/22 biological process terms (GO ID links to tree view) (see all 22):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IDA9099724
    GO:0002062chondrocyte differentiation ISS--
    GO:0006260DNA replication IEA--
    GO:0006351transcription, DNA-dependent ----
    GO:0006355regulation of transcription, DNA-dependent ----

    NFIB for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NFIB

    Search CenterWatch for drugs/clinical trials and news about NFIB

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NFIB gene (4 alternative transcripts): 
    NM_001190737.1  NM_001190738.1  NM_001282787.1  NM_005596.3  

    Unigene Cluster for NFIB:

    Nuclear factor I/B
    Hs.644095  [show with all ESTs]
    Unigene Representative Sequence: NM_001190737
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000380959(uc003zlf.3 uc003zle.3 uc022bdo.1) ENST00000380953
    ENST00000397575 ENST00000397581 ENST00000397579(uc011lmo.2) ENST00000380924
    ENST00000380921 ENST00000493697 ENST00000606230 ENST00000543693 ENST00000380934(uc003zld.3 uc022bdp.1)

    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

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    8/314 QIAGEN miScript miRNA Assays for microRNAs that regulate NFIB (see all 314):
    hsa-miR-124* hsa-miR-579 hsa-miR-361-5p hsa-miR-517a hsa-miR-1260b hsa-miR-605 hsa-miR-4275 hsa-miR-1243
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Clone
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    Additional mRNA sequence: 

    AF022215.1 AK021832.1 AK094066.1 AK129782.1 AK131233.1 AK290603.1 AK299605.1 AL110126.1 
    BC001283.1 BC024316.1 BT007266.1 BX537698.1 BX537707.1 BX648416.1 BX648845.1 U07810.1 
    U70862.1 U85193.1 

    21 DOTS entries:

    DT.450432  DT.100747327  DT.91662092  DT.91900755  DT.91920883  DT.102843149  DT.91768087  DT.95209847 
    DT.100747326  DT.121184205  DT.121184294  DT.40255520  DT.91768084  DT.100677274  DT.100737060  DT.70103842 
    DT.91768086  DT.95125504  DT.95209846  DT.100776919  DT.445767 

    24/432 AceView cDNA sequences (see all 432):

    AW673156 AI968059 CR619603 AI830644 AI668833 CR603516 BG742798 AA359363 
    BM669334 W81338 BE393582 AA129564 AA359126 W84385 AA232209 CA313748 
    BE857223 AA780523 AA977525 W84890 BU838464 BQ938394 BT007266 AI002281 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for NFIB    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11
    SP1:                                                                        
    SP2:                                                        -     -         


    ECgene alternative splicing isoforms for NFIB

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NFIB expression in normal human tissues (normalized intensities)      NFIB embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAACAAACCT
    NFIB Expression
    About this image


    NFIB expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/24 selected tissues (see all 24) fully expand
     
     Brain (Nervous System)    fully expand to see all 7 entries
             Cerebral Cortex
             brain/midbrain   
     
     Endothelium (Cardiovascular System)    fully expand to see all 5 entries
             Peripheral blood endothelial colony-forming cells
             Endothelial-like cells ( Derivation and purification of endothelial precursor cells...
             blood outgrowth endothelial cell   
     
     Uncategorized (Uncategorized)    fully expand to see all 4 entries
             PureStem Progenitor W10
     
     Lower Urinary Tract (Urinary System)    fully expand to see all 3 entries
             visceral organ/urethra of male/pelvic urethra of male   
     
     Neural Tube (Nervous System)    fully expand to see all 2 entries
             Metencephalon

    See NFIB Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NFIB

    SOURCE GeneReport for Unigene cluster: Hs.644095
        SABiosciences Expression via Pathway-Focused PCR Arrays including NFIB: 
              TGFB Signaling Targets in human mouse rat
              Cardiotoxicity in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NFIB

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for NFIB gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nfib1 , 5 nuclear factor I/B1, 5 94.34(n)1
    98.77(a)1
      4 (38.40 cM)5
    180281  NM_001113209.11  NP_001106680.11 
     822901735 
    chicken
    (Gallus gallus)
    Aves NFIB1 nuclear factor I/B 91.6(n)
    97.13(a)
      396209  NM_205272.1  NP_990603.1 
    lizard
    (Anolis carolinensis)
    Reptilia NFIB6
    nuclear factor I/B
    83(a)
    1 ↔ 1
    2(34156827-34354408)
    fruit fly
    (Drosophila melanogaster)
    Insecta CG23803 transcription factor 75(a)   102B3   --
    worm
    (Caenorhabditis elegans)
    Secernentea nfi-13 Nuclear factor 1 53(a)   II(7534429-7542464)   --


    ENSEMBL Gene Tree for NFIB (if available)
    TreeFam Gene Tree for NFIB (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NFIB gene
    NFIC2  NFIA2  NFIX2  
    7 SIMAP similar genes for NFIB using alignment to 8 protein entries:     NFIB_HUMAN (see all proteins):
    DKFZp686E13259    NFIX    NFI    NFIC    DKFZp686I05275    NFIA
    MYB/NFIB fusion

    NFIB for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/6841 SNPs in NFIB are shown (see all 6841)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1395261211,2
    --14081419(+) AGGGTA/GTCCCC 3 -- int10--------
    rs1435479531,2
    --14081425(+) TCCCCA/GGGGCT 3 -- int10--------
    rs1117402481,2
    C--14081508(+) ACATC-/AGTCTT 3 -- int11Minor allele frequency- A:0.50CSA 2
    rs169313241,2
    F--14081509(+) ACATCG/CTCTTC 3 -- int13Minor allele frequency- C:0.11NA 136
    rs1888239231,2
    --14081517(+) TTCAAC/TGTATT 3 -- int10--------
    rs1930934791,2
    --14081610(+) GAAAGA/CTTGGG 3 -- int10--------
    rs1403980861,2
    C--14081803(+) CAGAA-/CAGCAAGG 3 -- int10--------
    rs1141507211,2
    C,F--14081839(+) CATGAA/GGCCAG 3 -- int10--------
    rs10596061,2
    C--14082008(-) TTGCCA/CCAAGT 3 -- ut31 ese33Minor allele frequency- C:0.00MN NA 188
    rs1485628831,2
    C--14082066(+) CCAACA/CGGGCA 3 -- ut310--------

    HapMap Linkage Disequilibrium report for NFIB (14081842 - 14331842 bp, first 250kb of NFIB)

    Structural Variations
         Database of Genomic Variants (DGV) 10/21 variations for NFIB (see all 21):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2738221CNV Deletion23290073
    esv2673979CNV Deletion23128226
    esv2738223CNV Deletion23290073
    esv2738220CNV Deletion23290073
    esv2669830CNV Deletion23128226
    esv2738224CNV Deletion23290073
    esv2738222CNV Deletion23290073
    nsv526315CNV Loss19592680
    dgv480n21CNV Loss19592680
    nsv528796CNV Loss19592680

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 600728    OMIM disorders: --

    18 diseases for NFIB:    About MalaCards
    lipoma of colon    polymorphous low-grade adenocarcinoma    progressive multifocal leukoencephalopathy    lipoma
    adenoid cystic carcinoma    maturity-onset diabetes of the young    pleomorphic adenoma    adenoiditis
    hiv type 1    autism spectrum disorder    malignant glioma    adenoma
    hepatitis b    adenocarcinoma    hepatitis    lung cancer
    breast cancer    neuronitis

    4 diseases from the University of Copenhagen DISEASES database for NFIB:
    Adenoid cystic carcinoma     maturity-onset diabetes of the young     Lipoma of colon     Embryonal carcinoma

    NFIB for disorders           About GeneDecksing

    Genetic Association Database (GAD): NFIB
    Human Genome Epidemiology (HuGE) Navigator: NFIB (4 documents)

    Export disorders for NFIB gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NFIB gene, integrated from 9 sources (see all 45):
    (articles sorted by number of sources associating them with NFIB)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Chromosomal localization of the four genes (NFIA, B, C, and X) for the human transcription factor nuclear factor I by FISH. (PubMed id 7590749)1, 2, 3 Qian F....Sippel A.E. (1995)
    2. NFI-B3, a novel transcriptional repressor of the nuclear factor I family, is generated by alternative RNA processing. (PubMed id 9099724)1, 2, 9 Liu Y.... Apt D. (1997)
    3. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Identification of NFIB as recurrent translocation partner gene of HMGIC in pleomorphic adenomas. (PubMed id 9484777)1, 2 Geurts J.M.W.... van de Ven W.J.M. (1998)
    7. The C-terminal domain of the nuclear factor I-B2 isoform is glycosylated and transactivates the WAP gene in the JEG-3 cells. (PubMed id 17511965)1, 9 Mukhopadhyay S.S. and Rosen J.M. (2007)
    8. APOE and BCHE as modulators of cerebral amyloid deposi tion: a florbetapir PET genome-wide association study. (PubMed id 23419831)1 Ramanan V.K....Saykin A.J. (2013)
    9. MicroRNA profiling in pediatric pilocytic astrocytoma reveals biologically relevant targets, including PBX3, NFIB, and METAP2. (PubMed id 23161775)1 Ho C.Y....Rodriguez F.J. (2013)
    10. Studies of genomic imbalances and the MYB-NFIB gene f usion in polymorphous low-grade adenocarcinoma of the head and neck. (PubMed id 21901247)1 Persson F....Stenman G. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 4781 HGNC: 7785 AceView: NFIB Ensembl:ENSG00000147862 euGenes: HUgn4781
    ECgene: NFIB H-InvDB: NFIB

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NFIB Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for NFIB Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NFIB gene:
    Search GeneIP for patents involving NFIB

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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