Aliases for NFIB Gene
External Ids for NFIB Gene
Previous GeneCards Identifiers for NFIB Gene
GeneCards Summary for NFIB Gene
NFIB (Nuclear Factor I/B) is a Protein Coding gene. Diseases associated with NFIB include lipoma of colon and polymorphous low-grade adenocarcinoma. Among its related pathways are RNA Polymerase I Promoter Opening and Gene Expression. GO annotations related to this gene include RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and RNA polymerase II transcription corepressor activity. An important paralog of this gene is NFIX.
UniProtKB/Swiss-Prot for NFIB Gene
Recognizes and binds the palindromic sequence 5-TTGGCNNNNNGCCAA-3 present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication