Aliases for NFIA Gene
External Ids for NFIA Gene
Previous GeneCards Identifiers for NFIA Gene
This gene encodes a member of the NF1 (nuclear factor 1) family of transcription factors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
GeneCards Summary for NFIA Gene
NFIA (Nuclear Factor I/A) is a Protein Coding gene. Diseases associated with NFIA include 1p31p32 microdeletion syndrome and agenesis of the corpus callosum. Among its related pathways are RNA Polymerase I Promoter Opening and Gene Expression. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and transcription factor binding. An important paralog of this gene is NFIX.
UniProtKB/Swiss-Prot for NFIA Gene
Recognizes and binds the palindromic sequence 5-TTGGCNNNNNGCCAA-3 present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication