NFASC Gene
protein-coding GIFtS: 59
GCID: GC01P204797
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|
neurofascin(Previous name: neurofascin homolog (chicken) )
| |
Aliases
for NFASC gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Neurofascin1 | | FLJ468661 | | NF1 2 | | Neurofascin Homolog (Chicken)1 | | NRCAML1 2 | | Neurofascin Homolog2 | | KIAA07561 3 | | |
Export aliases for NFASC gene to outside databasesPrevious GC identifers: GC01P202615 GC01P200351 GC01P201158 GC01P202067 GC01P201645 GC01P203064 GC01P175963 |
Summaries
for NFASC gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for NFASC:
This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. Theprotein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) andnodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities ofvoltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteinsincluding this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AISextracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and thefull-length nature of some variants has not been determined.(provided by RefSeq, May 2009)
UniProtKB/Swiss-Prot: NFASC_HUMAN, O94856Function: Cell adhesion, ankyrin-binding protein which may be involved in neurite extension, axonal guidance,synaptogenesis, myelination and neuron-glial cell interactions (By similarity)
Gene Wiki entry for NFASC
|
Genomic Views
for NFASC gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004487.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the NFASC gene promoter:
NF-1 Sp1 p300 STAT3 Nkx2-5
Other transcription factors
Search SABiosciences Chromatin IP Primers for NFASC
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NFASC |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q32.1 Ensembl cytogenetic band: 1q32.1 HGNC cytogenetic band: 1q32.1NFASC Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P204797: view genomic region
(about GC identifiers)
Start:
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204,797,779 bp from pter |
End:
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204,991,950 bp from pter |
Size:
|
194,172 bases |
Orientation:
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plus strand |
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Proteins
for NFASC gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NFASC_HUMAN, O94856 (See
protein sequence)Recommended Name: Neurofascin precursor Size: 1347 amino acids; 150027 Da
Subunit: Horseshoe-shaped homodimer. Probable constituent of a neurofascin/NRCAM/ankyrin-G complex. Associates with thesodium channel beta-1 (SCN1B) and beta-3 (SCN3B) subunits. Interacts with GLDN/gliomedin (By similarity)
Subcellular location: Cell membrane; Single-pass type I membrane protein
Sequence caution: Sequence=BAA34476.3; Type=Erroneous initiation; Sequence=BAB55195.1; Type=Erroneous initiation;Sequence=BAC87577.1; Type=Erroneous initiation;
2 PDB 3D structures from  and Proteopedia  for NFASC:3P3Y (3D)
3P40 (3D)
Secondary accessions: B2RNN8 B3KQZ1 B5MDP6 B5MDR6 B7ZMD8 Q149P5 Q5T2F0 Q5T2F1 Q5T2F2 Q5T2F3 Q5T2F4Q5T2F5 Q5T2F6 Q5T2F7 Q5T2F9 Q5T2G0 Q5W9F8 Q68DH3 Q6ZQV6 Q7Z3K1 Q96HT1 Q96K50Alternative splicing: 13 isoforms: O94856-1 O94856-2 O94856-3 O94856-4 O94856-5 O94856-6 O94856-7 O94856-8 O94856-9 O94856-10 O94856-11 O94856-12 O94856-13 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for NFASC: NX_O94856
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O94856
NFASC Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (6 alternative transcripts):
NP_001005388.2 NP_001005389.2 NP_001153803.1 NP_001153804.1 NP_001153805.1 NP_055905.2
ENSEMBL proteins: ENSP00000412161 ENSP00000384875 ENSP00000385676 ENSP00000385637 ENSP00000427586 ENSP00000384061 ENSP00000425908 ENSP00000422524 ENSP00000415031 ENSP00000356141 ENSP00000395664 ENSP00000393290 ENSP00000416891 ENSP00000356140 ENSP00000356139 ENSP00000356138 ENSP00000342128 ENSP00000344786 ENSP00000343509 ENSP00000438614 ENSP00000353154 ENSP00000356137 Reactome Protein details: O94856
Human Recombinant Protein Products:
Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8): About this table
NFASC for ontologies About GeneDecksing
NFASC Antibody Products:
Assay Products for NFASC: |
Protein
Domains /
Families
for NFASC gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NFASC for domains About GeneDecksing
5/8 InterPro domains/families (see all 8):Graphical View of Domain Structure for InterPro Entry O94856ProtoNet protein and cluster: O94856 UniProtKB/Swiss-Prot: NFASC_HUMAN, O94856Domain: Homophilic adhesion is primarily mediated by the interaction of the second Ig-like domainsSimilarity: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM familySimilarity: Contains 5 fibronectin type-III domainsSimilarity: Contains 6 Ig-like C2-type (immunoglobulin-like) domains |
Function
for NFASC gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: NFASC_HUMAN, O94856Function: Cell adhesion, ankyrin-binding protein which may be involved in neurite extension, axonal guidance,synaptogenesis, myelination and neuron-glial cell interactions (By similarity)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NFASC (see all 11)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NFASC (see all 6)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 6): NFASC (NM_001005388) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NFASC | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NFASC |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NFASC |
Animal Models:
Mouse knock-out Nfasctm1.1Brp for NFASC
5 MGI mutant phenotypes (inferred from 5 alleles ) (MGI details for Nfasc):
NFASC for phenotypes About GeneDecksing
|
Pathways & Interactions
for NFASC gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Axon guidance | | | 2 | Neurofascin interactions | | | 3 | Interaction between L1 and Ankyrins | | | 4 | Cell adhesion molecules (CAMs) | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5 
Reactome Pathways for NFASC
1 
Kegg Pathway (Kegg details for NFASC):
NFASC for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NFASC
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/35 Interacting proteins for NFASC (O948563 ENSP000003531544) via UniProtKB, MINT, STRING, and/or I2D (see all 35)About this table
Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0002175 | protein localization to paranode region of axon |
IEA | -- | | GO:0007155 | cell adhesion |
IEA | -- | | GO:0007411 | axon guidance |
TAS | -- | | GO:0007422 | peripheral nervous system development |
ISS | -- | | GO:0019226 | transmission of nerve impulse |
-- | -- |
NFASC for ontologies About GeneDecksing
|
Drugs & Compounds
for NFASC gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
NFASC for compounds About GeneDecksing
 Browse Tocris compounds for NFASC
1 HMDB Compound for NFASC About this table
2 Novoseek chemical compound relationships for NFASC gene About this table
Search CenterWatch for drugs/clinical trials and news about NFASC
|
Transcripts
for NFASC gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for NFASC gene (7 alternative transcripts): NM_001005388.2 NM_001005389.1 NM_001160331.1 NM_001160332.1 NM_001160333.1 NM_015090.3 NM_001005387.1 Unigene Cluster for NFASC: Neurofascin Hs.13349 [show with all ESTs]Unigene Representative Sequence: NM_00100538818/32 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 32): ENST00000404977 ENST00000446412 ENST00000403080(uc001hbh.3 uc010pqz.2)
ENST00000493914 ENST00000404076 ENST00000514644(uc009xbg.1) ENST00000401399(uc001hbl.2 uc009xbh.2)
ENST00000505079 ENST00000404907 ENST00000513543 ENST00000504476 ENST00000430393
ENST00000367173 ENST00000504149 ENST00000512826(uc001hbk.1) ENST00000471392
ENST00000425360 ENST00000468328
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NFASC (see all 11)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NFASC (see all 6)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 6): NFASC (NM_001005388) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NFASC | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NFASC |
Additional cDNA sequence: AB018299.3 AB177861.1 AF054995.1 AK027553.1 AK090639.1 AK091338.1 AK097802.1 AK127205.1 AK127424.1 AK128699.1 AK172728.1 AK295291.1 AK299262.1 AK308686.1 BC008124.2 BC033367.1 BC035389.1 BC040674.1 BC117674.2 BC137013.1 BC144454.1 BX537841.1 BX641047.1 BX641048.1 BX647464.1 CR749402.1 21 DOTS entries: DT.404400 DT.314541 DT.97836305 DT.110862 DT.92066284 DT.97838242 DT.101982756 DT.110863 DT.91890351 DT.100017176 DT.100747099 DT.70103030 DT.75169797 DT.95333069 DT.95176130 DT.91981426 DT.121330329 DT.121330381 DT.75143885 DT.100714791 DT.92060805 24/188 AceView cDNA sequences (see all 188): CA843898 AK090639 AA670300 BQ188947 BF431751 CA843241 AL699776 AI393932 Z41725 BF433773 CK300307 F10987 AW026442 AK128699 BM718570 CF887580 H17930 BM671662 AK127424 BX645661 AB018299 BM726563 CA843141 BC033367
GeneLoc Exon Structure
5/11 Alternative Splicing Database (ASD) splice patterns (SP) for NFASC (see all 11) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19a | · | 19b | · | 19c | · | 19d | ^ | 20a | · |
|---|
|
| SP1: | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | |
| ExUns: | 20b | ^ | 21 | ^ | 22a | · | 22b | ^ | 23a | · | 23b | ^ | 24a | · | 24b | ^ | 25 | ^ | 26 | ^ | 27 | ^ | 28 | ^ | 29a | · | 29b | · | 29c | · | 29d |
|---|
|
| SP1: | - | | | | | | | | | | - | | - | | - | | - | | - | | | | | | | | | | | | | | |
| SP2: | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | - | | - | | - | | - | | | | | | | | | | | | | | | | |
| SP5: | - | | - | | | | | | | | - | | - | | - | | - | | - | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for NFASC
|
Expression
for NFASC gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NFASC expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGCAATGAAA
About this image
See NFASC Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NFASC
SOURCE GeneReport for Unigene cluster: Hs.13349
SABiosciences Expression via Pathway-Focused PCR Array including NFASC:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NFASC
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NFASC | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NFASC | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NFASC | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NFASC |
Orthologs
for NFASC gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for NFASC gene from 5/19 species (see all 19) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
NFASC1 |
neurofascin |
74.56(n)
76.82(a) |
|
419824 NM_001160322.1 NP_001153794.1 |
lizard
(Anolis carolinensis) |
Reptilia |
NFASC6 |
-- |
67(a) |
1 ↔ 1 |
4(116474297-116587959) |
zebrafish
(Danio rerio) |
Actinopterygii |
nfasca6CU234171.16 |
-- |
55(a)46(a) |
1 ↔ many1 ↔ many |
11(24630839-24802491) 23(18069975-18088703) |
fruit fly
(Drosophila melanogaster) |
Insecta |
Nrg3 |
neuronal cell adhesion cell adhesion
molecule |
32(a) |
|
-- |
worm
(Caenorhabditis elegans) |
Secernentea |
lad-13 |
neural adhesion protein |
26(a) |
|
IV(8062655-8082948) -- |
ENSEMBL Gene Tree for NFASC (if available)
TreeFam Gene Tree for NFASC (if available) |
Paralogs
for NFASC gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for NFASC gene
- CHL12 CNTN22 DSCAM2 CNTN62 CNTN52 CNTN42 NRCAM2 CNTN32
- SDK22 SDK12 DSCAML12 L1CAM2 CNTN12
10 SIMAP similar genes for NFASC using alignment to 12 protein entries: NFASC_HUMAN (see all proteins):NRCAM L1CAM CHL1 MUSK FGFR1 FGFR3
MDGA1 HMCN2 CNTN1 CNTN3
NFASC for paralogs About GeneDecksing
|
Genomic Variants
for NFASC gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for NFASC (204797779 - 204991950 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for NFASC: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NFASC |
|
Disorders
/ Diseases
for NFASC gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NFASC for disorders About GeneDecksing
OMIM gene information: 609145
OMIM disorders: --
12  diseases for NFASC: About MalaCardsmaturity-onset diabetes of the young dengue hemorrhagic fever hemorrhagic fever masa syndrome
crash syndrome lissencephaly hydrocephalus multiple sclerosis
parkinson's disease hepatocellular carcinoma carcinoma neuronitis
2 diseases from the University of Copenhagen DISEASES database for NFASC:Hyperkalemic periodic paralysis Demyelinating polyneuropathy Human Genome Epidemiology (HuGE) Navigator: NFASC (2 documents)
Export disorders for NFASC gene to outside databases
|
Publications
for NFASC gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NFASC gene, integrated from 9 sources (see all 80):
(articles sorted by number of sources associating them with NFASC) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Homophilic adhesion mechanism of neurofascin, a membe r of the L1 family of neural cell adhesion molecules. (PubMed id 21047790)1, 2 Liu H....He X. (2011)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- Alternative splice variants encoding unstable protein domains exist in the human brain. (PubMed id 15491607)1, 2 Homma K.... Nishikawa K. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (2002)
- Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9872452)1, 2 Nagase T.... Ohara O. (1998)
- Genes for the neuronal immunoglobulin domain cell adhesion molecules neurofascin and Nr-CAM map to mouse chromosomes 1 and 12 and homologous human chromosomes. (PubMed id 8672144)1, 3 Burmeister M....Bennett V. (1996)
- Structure of the axonal surface recognition molecule neurofascin and its relationship to a neural subgroup of the immunoglobulin superfamily. (PubMed id 1377696)1, 3 Volkmer H....Rathjen F.G. (1992)
- Palmitoylation of neurofascin at a site in the membrane-spanning domain highly conserved among the L1 family of cell adhesion molecules. (PubMed id 9572267)1, 9 Ren Q. and Bennett V. (1998)
|
External Searches for NFASC gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing NFASC gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
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Other Databases showing NFASC gene
(According to HUGE)
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Specialized Databases showing NFASC gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Name | Description |
| PharmGKB entry for NFASC | Pharmacogenomics, SNPs, Pathways |
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| Patent Information for NFASC gene:
Search GeneIP for patents involving NFASC
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for NFASC gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NFASC | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NFASC | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for NFASC | | OriGene 3'-UTR Clone for NFASC | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NFASC | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NFASC | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for NFASC | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for NFASC | | OriGene Custom Protein Services for NFASC | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NFASC | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NFASC | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NFASC | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NFASC | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NFASC | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NFASC |
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| | | | Search Tocris compounds for NFASC |
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 | | | NFASC Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NFASC |
|  |  |  | | | | Search ThermoFisher Antibodies for NFASC |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NFASC |
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