Aliases for NEXN Gene
External Ids for NEXN Gene
Previous GeneCards Identifiers for NEXN Gene
This gene encodes a filamentous actin-binding protein that may function in cell adhesion and migration. Mutations in this gene have been associated with dilated cardiomyopathy, also known as CMD1CC. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]
GeneCards Summary for NEXN Gene
NEXN (Nexilin F-Actin Binding Protein) is a Protein Coding gene. Diseases associated with NEXN include cardiomyopathy, dilated, 1cc and cardiomyopathy, hypertrophic, 20. GO annotations related to this gene include actin filament binding and calmodulin-dependent protein kinase activity.
UniProtKB/Swiss-Prot for NEXN Gene
Involved in regulating cell migration through association with the actin cytoskeleton. Has an essential role in the maintenance of Z line and sarcomere integrity.