Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



NEUROD6 Gene

protein-coding   GIFtS: 46
GCID: GC07M031343

Neuronal Differentiation 6

(Previous name: neurogenic differentiation 6)
  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Neuronal Differentiation 61 2     Math-22
Class A Basic Helix-Loop-Helix Protein 22 3     NEX1M2
Protein Atonal Homolog 22 3     Nex12
bHLHa22 3     Brain My051 Protein2
MATH22 5     Neurogenic Differentiation Factor 62
ATOH23 5     BHLHA23
Neurogenic Differentiation 61     NeuroD63
Atoh22     

External Ids:    HGNC: 138041   Entrez Gene: 639742   Ensembl: ENSG000001646007   OMIM: 6115135   UniProtKB: Q96NK83   

Export aliases for NEUROD6 gene to outside databases

Previous GC identifers: GC07M031019 GC07M031119 GC07M031150


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for NEUROD6 Gene:
This gene is a member of the NEUROD family of basic helix-loop-helix transcription factors. The encoded protein
may be involved in the development and differentiation of the nervous system. (provided by RefSeq, Nov 2012)

GeneCards Summary for NEUROD6 Gene:
NEUROD6 (neuronal differentiation 6) is a protein-coding gene. GO annotations related to this gene include protein dimerization activity. An important paralog of this gene is NEUROG3.

UniProtKB/Swiss-Prot: NDF6_HUMAN, Q96NK8
Function: Activates E box-dependent transcription in collaboration with TCF3/E47. May be a trans-acting factor
involved in the development and maintenance of the mammalian nervous system. Transactivates the promoter of its
own gene (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000007.13  NC_018918.2  NT_007819.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the NEUROD6 gene promoter:
         E2F-4   E2F-3a   E2F-5   AP-1   ATF-2   E2F-2   HEN1   E2F-1   E2F   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNEUROD6 promoter sequence
   Search Chromatin IP Primers for NEUROD6

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NEUROD6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p14.3   Ensembl cytogenetic band:  7p14.3   HGNC cytogenetic band: 7p15.1

NEUROD6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NEUROD6 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M031343:  view genomic region     (about GC identifiers)

Start:
31,377,075 bp from pter      End:
31,380,538 bp from pter
Size:
3,464 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 31,426,281-31,429,739     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: NDF6_HUMAN, Q96NK8 (See protein sequence)
Recommended Name: Neurogenic differentiation factor 6  
Size: 337 amino acids; 38705 Da
Subunit: Efficient DNA binding requires dimerization with another bHLH protein (By similarity)
Sequence caution: Sequence=AAG43167.1; Type=Frameshift; Positions=300, 307;
Secondary accessions: Q548T9 Q9H3H6

Explore the universe of human proteins at neXtProt for NEUROD6: NX_Q96NK8

Explore proteomics data for NEUROD6 at MOPED


See NEUROD6 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_073565.2  
ENSEMBL proteins: 
 ENSP00000297142  

NEUROD6 Human Recombinant Protein Products:

Browse Purified and Recombinant Proteins at EMD Millipore
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
OriGene Protein Over-expression Lysate for NEUROD6
OriGene Custom MassSpec
OriGene Custom Protein Services for NEUROD6
GenScript Custom Purified and Recombinant Proteins Services for NEUROD6
Novus Biologicals NEUROD6 Proteins
Novus Biologicals NEUROD6 Lysate
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates
Browse ProSpec Recombinant Proteins
Cloud-Clone Corp. Proteins for NEUROD6

 
Search eBioscience for Proteins for NEUROD6 

NEUROD6 Antibody Products:

EMD Millipore Mono- and Polyclonal Antibodies for the study of NEUROD6
Browse R&D Systems for Antibodies
Browse OriGene Antibodies
OriGene Custom Antibody Services for NEUROD6
Novus Biologicals NEUROD6 Antibodies
Search for Antibodies for NEUROD6 at Abcam
Cloud-Clone Corp. Antibodies for NEUROD6
Search ThermoFisher Antibodies for NEUROD6
LSBio Antibodies in human, mouse, rat for NEUROD6

NEUROD6 Assay Products:

Browse Kits and Assays available from EMD Millipore
OriGene Custom Assay Services for NEUROD6
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for NEUROD6
Browse Enzo Life Sciences for kits & assays
Cloud-Clone Corp. ELISAs for NEUROD6
Cloud-Clone Corp. CLIAs for NEUROD6
Search eBioscience for ELISAs for NEUROD6 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TryGeneCards Plus
HGNC Gene Families:
bHLH: Basic helix-loop-helix proteins

3 InterPro protein domains:
 IPR011598 bHLH_dom
 IPR022575 Neurogenic_DUF
 IPR016637 TF_bHLH_NeuroD

Graphical View of Domain Structure for InterPro Entry Q96NK8

ProtoNet protein and cluster: Q96NK8

1 Blocks protein domain: IPB001092 Basic helix-loop-helix dimerization domain bHLH

UniProtKB/Swiss-Prot: NDF6_HUMAN, Q96NK8
Similarity: Contains 1 bHLH (basic helix-loop-helix) domain


Find genes that share domains with NEUROD6           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Molecular Function:

     UniProtKB/Swiss-Prot Summary: NDF6_HUMAN, Q96NK8
Function: Activates E box-dependent transcription in collaboration with TCF3/E47. May be a trans-acting factor
involved in the development and maintenance of the mammalian nervous system. Transactivates the promoter of its
own gene (By similarity)

     Gene Ontology (GO): 2 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003677DNA binding IEA--
GO:0046983protein dimerization activity IEA--
     
Find genes that share ontologies with NEUROD6           About GenesLikeMe


Phenotypes:
     10 MGI mutant phenotypes (inferred from 4 alleles(MGI details for Neurod6):
 behavior/neurological  cardiovascular system  cellular  digestive/alimentary  growth/size/body 
 homeostasis/metabolism  mortality/aging  nervous system  no phenotypic analysis  normal 

Find genes that share phenotypes with NEUROD6           About GenesLikeMe

Animal Models:
     MGI mouse knock-out Neurod6tm1Kan for NEUROD6

   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NEUROD6
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for NEUROD6

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NEUROD6
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NEUROD6

miRNA
Products:
    
Block miRNA regulation of human, mouse, rat NEUROD6 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate NEUROD6 (see all 13):
hsa-miR-579 hsa-miR-495 hsa-miR-7-2* hsa-miR-128 hsa-miR-3681* hsa-miR-1257 hsa-miR-153 hsa-miR-7-1*
SwitchGear 3'UTR luciferase reporter plasmidNEUROD6 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for NEUROD6
Predesigned siRNA for gene silencing in human, mouse, rat NEUROD6

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for NEUROD6

Clone
Products:
     
OriGene clones in human, mouse for NEUROD6 (see all 6)
OriGene ORF clones in mouse, rat for NEUROD6
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: NEUROD6 (NM_022728)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for NEUROD6
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NEUROD6

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for NEUROD6
Browse ESI BIO Cell Lines and PureStem Progenitors for NEUROD6 
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NEUROD6


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Subcellular locations from UniProtKB/Swiss-Prot
NDF6_HUMAN, Q96NK8: Nucleus (Probable)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
nucleus4
cytosol2
mitochondrion1

Gene Ontology (GO): 1 cellular component term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IEA--

Find genes that share ontologies with NEUROD6           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
About This Section

TryGeneCards Plus

SuperPaths for NEUROD6 About    
See pathways by source

SuperPathContained pathways About
1Selected targets of C EBPbeta
Selected targets of C EBPbeta



    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NEUROD6
Interactions:

    Search GeneGlobe Interaction Network for NEUROD6

STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

3 Interacting proteins for NEUROD6 (Q96NK83 ENSP000002971424) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
HMGB1P094293, ENSP000003430404I2D: score=1 STRING: ENSP00000343040
UBCENSP000003448184STRING: ENSP00000344818
ID4ENSP000003679724STRING: ENSP00000367972
About this table

Gene Ontology (GO): 4 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006351transcription, DNA-templated IEA--
GO:0006355regulation of transcription, DNA-templated IEA--
GO:0021542dentate gyrus development IEA--
GO:0030154cell differentiation IEA--

Find genes that share ontologies with NEUROD6           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
About This Section

TryGeneCards Plus
Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for NEUROD6 (NDF6)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
About This Section

TryGeneCards Plus

REFSEQ mRNAs for NEUROD6 gene: 
NM_022728.3  

Unigene Cluster for NEUROD6:

Neuronal differentiation 6
Hs.45152  [show with all ESTs]
Unigene Representative Sequence: AF248954
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000297142(uc003tch.3)
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat NEUROD6 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate NEUROD6 (see all 13):
hsa-miR-579 hsa-miR-495 hsa-miR-7-2* hsa-miR-128 hsa-miR-3681* hsa-miR-1257 hsa-miR-153 hsa-miR-7-1*
SwitchGear 3'UTR luciferase reporter plasmidNEUROD6 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for NEUROD6
Predesigned siRNA for gene silencing in human, mouse, rat NEUROD6
Clone
Products:
     
OriGene clones in human, mouse for NEUROD6 (see all 6)
OriGene ORF clones in mouse, rat for NEUROD6
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: NEUROD6 (NM_022728)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for NEUROD6
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NEUROD6
Primer
Products:
    
OriGene qPCR primer pairs and template standards for NEUROD6
OriGene qSTAR qPCR primer pairs in human, mouse for NEUROD6
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NEUROD6
  QuantiTect SYBR Green Assays in human, mouse, rat NEUROD6
  QuantiFast Probe-based Assays in human, mouse, rat NEUROD6

Additional mRNA sequence: 

AF063609.1 AF136169.1 AF248954.1 AK055238.1 AK289619.1 BC022560.1 BC035048.2 

3 DOTS entries:

DT.445048  DT.100812759  DT.95346064 

Selected AceView cDNA sequences (see all 38):

BC022560 AK055238 CR624239 AF248954 NM_022728 H18504 BX478059 BX951578 
D80123 AF063609 AW236965 BX420750 BI547130 CB155186 BX453565 AF136169 
AW163081 BX419494 BC035048 BG699059 U69205 M78507 BI918896 BX413652 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TryGeneCards Plus

NEUROD6 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
NEUROD6 Expression
About this image


NEUROD6 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 5) fully expand
 
 Neurons
         nGnG Amacrine Cells Inner Nuclear Layer
 
 Brain (Nervous System)    fully expand to see all 5 entries
         Endothelial Cells Blood Brain Barrier
         Midbrain tegmentum
 
 Eye (Sensory Organs)    fully expand to see all 2 entries
         nGnG Amacrine Cells Inner Nuclear Layer
 
 Neural Tube (Nervous System)    fully expand to see all 3 entries
         Metencephalon
 
 Endothelium (Cardiovascular System)    fully expand to see all 2 entries
         Endothelial Cells Blood Brain Barrier
NEUROD6 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

NEUROD6 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.45152
    Custom PCR Arrays for NEUROD6
Primer
Products:
OriGene qPCR primer pairs and template standards for NEUROD6
OriGene qSTAR qPCR primer pairs in human, mouse for NEUROD6
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NEUROD6
QuantiTect SYBR Green Assays in human, mouse, rat NEUROD6
QuantiFast Probe-based Assays in human, mouse, rat NEUROD6
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NEUROD6

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

TryGeneCards Plus

This gene was present in the common ancestor of animals.

Orthologs for NEUROD6 gene from Selected species (see all 13)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Neurod61 , 5 neurogenic differentiation 61, 5 94.16(n)1
98.22(a)1
  6 (27.53 cM)5
119221  NM_009717.21  NP_033847.11 
 556778185 
chicken
(Gallus gallus)
Aves NEUROD61 neuronal differentiation 6 86.65(n)
94.07(a)
  420754  XM_418852.4  XP_418852.1 
lizard
(Anolis carolinensis)
Reptilia NEUROD66
neuronal differentiation 6
90(a)
1 ↔ 1
6(44530862-44531875)
African clawed frog
(Xenopus laevis)
Amphibia neurod6-A2 bHLH transcription factor atonal homolog 2 80.98(n)    AF306736.1 
zebrafish
(Danio rerio)
Actinopterygii atoh2a2 atonal homolog 2a 72.57(n)   114414  AF115772.1 
worm
(Caenorhabditis elegans)
Secernentea cnd-11 cnd-1 50.11(n)
45.03(a)
  183212  NM_065714.5  NP_498115.1 


ENSEMBL Gene Tree for NEUROD6 (if available)
TreeFam Gene Tree for NEUROD6 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section

TryGeneCards Plus
Paralogs for NEUROD6 gene
NEUROG32  NEUROD22  NEUROG22  NEUROD12  ATOH12  BHLHA152  ATOH72  NEUROG12  
NEUROD42  
6 SIMAP similar genes for NEUROD6 using alignment to 2 protein entries:     NDF6_HUMAN (see all proteins):
ATOH7    TAL2    NEUROD1    NEUROD2    NEUROD4    FERD3L

Find genes that share paralogs with NEUROD6           About GenesLikeMe



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section

TryGeneCards Plus

Selected SNPs for NEUROD6 (see all 130)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 7 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs132465901,2
C,F--31376584(+) CTTGGC/AGAGGT 1 -- ds50016Minor allele frequency- A:0.11NA WA 246
rs1892932861,2
--31376602(+) ACCCCA/GCCCAT 1 -- ds50010--------
rs730860511,2
C,F--31376787(+) TGTTTG/TTTGGA 1 -- ds50013Minor allele frequency- T:0.11WA NA EA 358
rs570416541,2
C,F--31376828(+) AGGTTA/GCCAGG 1 -- ds50012Minor allele frequency- G:0.11CSA WA 120
rs1929224571,2
--31376940(+) TTTAAG/TAAATT 1 -- ds50010--------
rs1851051981,2
--31377020(+) GAAAGC/TAGCTG 1 -- ds50010--------
rs1451053241,2
--31377029(+) TGTGTA/GCCAGG 1 -- ds50010--------
rs102389181,2
C,F,A,H--31377369(+) CAAATT/GCATCT 1 -- ut31 ese328Minor allele frequency- G:0.26NS EA NA WA CSA 2775
rs1896812731,2
--31377524(+) CAACCA/CAAATA 1 -- ut310--------
rs1811559081,2
--31377552(+) TGTGCA/CTGTCT 1 -- ut310--------

HapMap Linkage Disequilibrium report for NEUROD6 (31377075 - 31380538 bp)

Structural Variations
     Database of Genomic Variants (DGV) 2 variations for NEUROD6:    About this table    
Variant IDTypeSubtypePubMed ID
nsv436557CNV Deletion17901297
nsv830940CNV Gain17160897

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing NEUROD6
DNA2.0 Custom Variant and Variant Library Synthesis for NEUROD6

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TryGeneCards Plus
OMIM gene information: 611513    OMIM disorders: --


Find genes that share disorders with NEUROD6           About GenesLikeMe

Genetic Association Database (GAD): NEUROD6
Human Genome Epidemiology (HuGE) Navigator: NEUROD6 (1 document)

Export disorders for NEUROD6 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

TryGeneCards Plus

PubMed articles for NEUROD6 gene integrated from 10 sources:
(articles sorted by number of sources associating them with NEUROD6)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Cloning, chromosome localization and features of a novel human gene, MATH2. (PubMed id 12357074)1, 2, 3 Guo L.... Mao Y.-M. (J. Genet. 2002)
  2. Case-control study of six genes asymmetrically expressed in the two cerebral hemispheres: association of BAIAP2 with attention-deficit/hyperactivity disorder. (PubMed id 19733838)1, 4 RibasAcs M....Cormand B. (Biol. Psychiatry 2009)
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
  4. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
  5. Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham Study. (PubMed id 17903297)4 Seshadri S....Wolf P.A. (BMC Med. Genet. 2007)
  6. AT-hook proteins stimulate induction of senescence markers triggered by 5-bromodeoxyuridine in mammalian cells. (PubMed id 15036409)1 Satou W....Ayusawa D. (Exp. Gerontol. 2004)
  7. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1 Scherer S.W.... Tsui L.-C. (Science 2003)
  8. HMGB1 interacts with many apparently unrelated proteins by recognizing short amino acid sequences. (PubMed id 11748221)1 Dintilhac A. and BernuAcs J. (J. Biol. Chem. 2002)
  9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

TryGeneCards Plus
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

TryGeneCards Plus
Entrez Gene: 63974 HGNC: 13804 AceView: NEUROD6 Ensembl:ENSG00000164600 euGenes: HUgn63974
ECgene: NEUROD6 H-InvDB: NEUROD6

(According to HUGE)
About This Section

TryGeneCards Plus
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
About This Section

TryGeneCards Plus
NameDescription
PharmGKB entry for NEUROD6 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section

TryGeneCards Plus
Patent Information for NEUROD6 gene:
Search GeneIP for patents involving NEUROD6

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section

TryGeneCards Plus

 Browse Small Molecules at EMD Millipore
 Browse Kits and Assays available from EMD Millipore
 EMD Millipore Mono- and Polyclonal Antibodies for the study of NEUROD6
 Browse Purified and Recombinant Proteins at EMD Millipore
 
 EMD Millipore genomic analysis products

  
 Browse Antibodies   Browse Cell Culture Products  
 Browse ELISAs   Browse Flow Cytometry Kits  
 Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
 Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
 Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
 Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
 Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
 Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
 Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for NEUROD6  
 OriGene qPCR primer pairs and template standards for NEUROD6   OriGene Protein Over-expression Lysate for NEUROD6  
 OriGene Custom Mass Spec   OriGene clones in human, mouse for NEUROD6  
 OriGene qSTAR qPCR primer pairs in human, mouse for NEUROD6   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
 OriGene ORF clones in mouse, rat for NEUROD6   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for NEUROD6   OriGene Custom Protein Services for NEUROD6  

 
 
 Block miRNA regulation of human, mouse, rat NEUROD6 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing NEUROD6
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NEUROD6 Predesigned siRNA for gene silencing in human, mouse, rat NEUROD6
 QuantiFast Probe-based Assays in human, mouse, rat NEUROD6 QuantiTect SYBR Green Assays in human, mouse, rat NEUROD6
 Custom PCR Arrays for NEUROD6 Search Chromatin IP Primers for NEUROD6
 Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NEUROD6  Search GeneGlobe Interaction Network for NEUROD6
 Regulatory tfbs in NEUROD6 promoter
 GenScript Custom Purified and Recombinant Proteins Services for NEUROD6 GenScript cDNA clones with any tag delivered in your preferred vector for NEUROD6
 GenScript Custom Assay Services for NEUROD6 GenScript Custom overexpressing Cell Line Services for NEUROD6
 CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
 Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
 Plasmid Preparation Custom Peptide Services
 Search for Antibodies & Assays

 Search Tocris compounds for NEUROD6 (NDF6)
 Browse Sino Biological Proteins
 Browse Sino Biological Cell Lysates
 Browse Sino Biological cDNA Clones
 4000+ Proteins
 Search Sino Biological for antibodies, proteins & pathways
 Protein Production Services
 Transfection Reagents
 Protein A/G/L resins
 Isotyping reagents
 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
 NEUROD6 antibodies
 NEUROD6 proteins
 NEUROD6 lysates
 Search for Antibodies for NEUROD6 at Abcam
 See all of Abcam's Antibodies, Kits and Proteins for NEUROD6
 Custom Antibody / Protein Production Service
 Bulk Purchasing
 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins
 Proteins for NEUROD6
 Antibodies for NEUROD6
 ELISAs for NEUROD6
 CLIAs for NEUROD6



 Browse ESI BIO Cell Lines and PureStem Progenitors for NEUROD6
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NEUROD6
 SwitchGear 3'UTR luciferase reporter plasmids for NEUROD6
 SwitchGear Promoter luciferase reporter plasmids for NEUROD6
 Search ThermoFisher Antibodies for NEUROD6
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NEUROD6
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NEUROD6
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for NEUROD6
 LSBio Antibodies in human, mouse, rat for NEUROD6
Customized transgenic rodents for:
 Humanization
 Biomarker expression
 Off-target effect monitoring
 Translational medicine
 Tissue-specific gene expresssion
 Time-controlled gene expresssion
 Browse compounds at ApexBio
 Search Addgene for plasmids for NEUROD6
  Search eBioscience for proteins for NEUROD6
  Search eBioscience for elisas for NEUROD6
  eBioscience FlowRNA Probe Sets
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

View Random Gene

Category
(GIFtS: )
GIFtS Group
The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes      Disease genes      NEUROD6 gene at Home site.
Version: 3.12.224 13 Oct 2014
hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4