Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NEURL2 Gene

protein-coding   GIFtS: 43
GCID: GC20M044517

Neuralized Homolog 2 (Drosophila)

(Previous names: chromosome 20 open reading frame 163, neuralized-like 2...)
(Previous symbol: C20orf163)
  Search for NEURL2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Neuralized Homolog 2 (Drosophila)1 2     OZZ2
C20orf1631 2 3     OZZ-E32
Chromosome 20 Open Reading Frame 1631     Neuralized-Like Protein 22
Neuralized-Like 2 (Drosophila)1     

External Ids:    HGNC: 161561   Entrez Gene: 1408252   Ensembl: ENSG000001242577   OMIM: 6085975   UniProtKB: Q9BR093   

Export aliases for NEURL2 gene to outside databases

Previous GC identifers: GC20M045203 GC20M043950 GC20M041259


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NEURL2 Gene:
This gene encodes a protein that is involved in the regulation of myofibril organization. This protein is likely
the adaptor component of the E3 ubiquitin ligase complex in striated muscle, and it regulates the
ubiquitin-mediated degradation of beta-catenin during myogenesis. Alternative splicing of this gene results in
multiple transcript variants. (provided by RefSeq, Jun 2013)

GeneCards Summary for NEURL2 Gene: 
NEURL2 (neuralized homolog 2 (Drosophila)) is a protein-coding gene. An important paralog of this gene is NEURL4.

UniProtKB/Swiss-Prot: NEUL2_HUMAN, Q9BR09
Function: Plays an important role in the process of myofiber differentiation and maturation. Probable
substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein
ligase complex, which mediates the ubiquitination of proteins. Probably contributes to catalysis through
recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, controls
the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma (By
similarity)

Gene Wiki entry for NEURL2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NEURL2 gene promoter:
         TBP   NF-1/L   Nkx2-5   NF-kappaB   Tal-1beta   GATA-2   YY1   E47   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNEURL2 promoter sequence
   Search SABiosciences Chromatin IP Primers for NEURL2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NEURL2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.12   Ensembl cytogenetic band:  20q13.12   HGNC cytogenetic band: 20q13.12

NEURL2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NEURL2 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20M044517:  view genomic region     (about GC identifiers)

Start:
44,517,264 bp from pter      End:
44,519,926 bp from pter
Size:
2,663 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NEUL2_HUMAN, Q9BR09 (See protein sequence)
Recommended Name: Neuralized-like protein 2  
Size: 285 amino acids; 31690 Da
Subunit: Probable component the ECS(NEURL2) E3 ubiquitin-protein ligase complex consisting of TCEB2/Elongin B,
TCEB1/Elongin C, CUL5, RBX1 and NEURL2. Interacts with CTNNB1 (By similarity)
Subcellular location: Cytoplasm (By similarity)
Secondary accessions: Q3KR34

Explore the universe of human proteins at neXtProt for NEURL2: NX_Q9BR09

Explore proteomics data for NEURL2 at MOPED 

NEURL2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

NEURL2 Protein Expression

REFSEQ proteins (2 alternative transcripts): 
NP_001265464.1  NP_542787.1  

ENSEMBL proteins: 
 ENSP00000442383   ENSP00000361596  

Human Recombinant Protein Products for NEURL2: 
Browse Purified and Recombinant Proteins at EMD Millipore
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
OriGene Protein Over-expression Lysate for NEURL2
OriGene Custom MassSpec 
OriGene Custom Protein Services for NEURL2
GenScript Custom Purified and Recombinant Proteins Services for NEURL2
Novus Biologicals NEURL2 Protein
Novus Biologicals NEURL2 Lysate
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates 
Browse ProSpec Recombinant Proteins
Cloud-Clone Corp. Proteins for NEURL2 

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005927muscle tendon junction IEA--
GO:0030891VCB complex IEA--

NEURL2 for ontologies           About GeneDecksing



NEURL2 Antibody Products: 
Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Browse R&D Systems for Antibodies
Browse OriGene Antibodies
OriGene Custom Antibody Services for NEURL2
GenScript Custom Superior Antibodies Services for NEURL2
Novus Biologicals NEURL2 Antibodies
Search for Antibodies for NEURL2 at Abcam
Cloud-Clone Corp. Antibodies for NEURL2 
Search ThermoFisher Antibodies for NEURL2
LSBio Antibodies in human, mouse, rat for NEURL2 

Assay Products for NEURL2: 
Browse Kits and Assays available from EMD Millipore
OriGene Custom Assay Services for NEURL2
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for NEURL2
Browse Enzo Life Sciences for kits & assays
Cloud-Clone Corp. ELISAs for NEURL2 
Cloud-Clone Corp. CLIAs for NEURL2


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
2 InterPro protein domains:
 IPR006573 Neu_Z
 IPR001496 SOCS_C

Graphical View of Domain Structure for InterPro Entry Q9BR09

ProtoNet protein and cluster: Q9BR09

1 Blocks protein domain: IPB001496 SOCS protein

UniProtKB/Swiss-Prot: NEUL2_HUMAN, Q9BR09
Domain: The SOCS domain mediates the interaction with TCEB1 and TCEB2, while the NHR domain may be involved in
ubiquitination substrate binding (By similarity)
Similarity: Contains 1 NHR (neuralized homology repeat) domain
Similarity: Contains 1 SOCS box domain


NEURL2 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: NEUL2_HUMAN, Q9BR09
Function: Plays an important role in the process of myofiber differentiation and maturation. Probable
substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein
ligase complex, which mediates the ubiquitination of proteins. Probably contributes to catalysis through
recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, controls
the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma (By
similarity)

     Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005515protein binding ----
     
NEURL2 for ontologies           About GeneDecksing


Phenotypes:
     1 GenomeRNAi human phenotype for NEURL2:
 Metaphase cells 

     4 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Neurl2):
 growth/size  muscle  nervous system  normal 

NEURL2 for phenotypes           About GeneDecksing

Animal Models:
     MGI mouse knock-out Neurl2tm1Adz for NEURL2

   inGenious Targeting Laboratory - Custom generated mouse model solutions for NEURL2 
   inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for NEURL2

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NEURL2 
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NEURL2 

miRNA
Products:
    
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NEURL2
Search QIAGEN for miScript miRNA Assays for microRNAs that regulate NEURL2
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
    
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for NEURL2
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NEURL2

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for NEURL2
Sirion Biotech Customized adenovirus for overexpression of NEURL2

Clone
Products:
     
Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
OriGene clones in human, mouse for NEURL2 (see all 6)
OriGene ORF clones in mouse, rat for NEURL2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: NEURL2 (NM_080749)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for NEURL2
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NEURL2
Sirion Biotech Customized lentivirus for stable overexpression of NEURL2 
                     Customized lentivirus expression plasmids for stable overexpression of NEURL2 

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for NEURL2
Search LifeMap BioReagents cell lines for NEURL2
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NEURL2


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section



UniProtKB/Swiss-Prot: NEUL2_HUMAN, Q9BR09
Pathway: Protein modification; protein ubiquitination

Interactions:

    SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NEURL2

STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

5/8 Interacting proteins for NEURL2 (Q9BR093 ENSP000003615964) via UniProtKB, MINT, STRING, and/or I2D (see all 8)

InteractantInteraction Details
GeneCardExternal ID(s)
CTNNB1P352223, ENSP000003444564I2D: score=2 STRING: ENSP00000344456
TCEB2Q153703I2D: score=1 
ATG3ENSP000002832904STRING: ENSP00000283290
OS9ENSP000003181654STRING: ENSP00000318165
RBX1ENSP000002162254STRING: ENSP00000216225
About this table

Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0016567protein ubiquitination IEA--
GO:0030239myofibril assembly ----
GO:0035556intracellular signal transduction IEA--
GO:0045214sarcomere organization IEA--

NEURL2 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for NEURL2 (NEUL2)

Search CenterWatch for drugs/clinical trials and news about NEURL2 / NEUL2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for NEURL2 gene (2 alternative transcripts): 
NM_001278535.1  NM_080749.3  

2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000545238 ENST00000372518(uc002xqg.1)
miRNA
Products:
     
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NEURL2
Search QIAGEN for miScript miRNA Assays for microRNAs that regulate NEURL2
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for NEURL2
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NEURL2
Clone
Products:
     
OriGene clones in human, mouse for NEURL2 (see all 6)
OriGene ORF clones in mouse, rat for NEURL2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: NEURL2 (NM_080749)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for NEURL2
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NEURL2
Sirion Biotech Customized lentivirus for stable overexpression of NEURL2 
                     Customized lentivirus expression plasmids for stable overexpression of NEURL2 
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for NEURL2
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NEURL2
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NEURL2
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NEURL2

24/26 AceView cDNA sequences (see all 26):

AK054821 AI078253 AW298115 AJ295985 NM_080749 AW515245 CA425681 AW305049 
AL844375 BX409810 F34149 BP367504 BX115239 CD674633 AI589199 BX409811 
BX441365 BC074737 AL844254 AI097227 CB269672 AW298116 AA971892 F34155 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

NEURL2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GTGCACCGGC
NEURL2 Expression
About this image


See NEURL2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NEURL2

UniProtKB/Swiss-Prot: NEUL2_HUMAN, Q9BR09
Tissue specificity: Expressed specifically in skeletal and cardiac muscles

    SABiosciences Custom PCR Arrays for NEURL2
Primer
Products:
OriGene qSTAR qPCR primer pairs in human, mouse for NEURL2
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NEURL2
QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NEURL2
QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NEURL2
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NEURL2

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for NEURL2 gene from 5/11 species (see all 11)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Neurl21 , 5 neuralized-like 2 (Drosophila)1, 5 84.68(n)1
90.53(a)1
  2 (85.27 cM)5
4151151  NM_001082974.21  NP_001076443.11 
 1648307325 
chicken
(Gallus gallus)
Aves NEURL21 neuralized homolog 2 (Drosophila) 74.81(n)
75.95(a)
  428162  XM_425720.2  XP_425720.2 
lizard
(Anolis carolinensis)
Reptilia NEURL26
Uncharacterized protein
70(a)
1 ↔ 1
AAWZ02036849(7238-21141)
zebrafish
(Danio rerio)
Actinopterygii zgc:1621871 zgc:162187 61.28(n)
64.23(a)
  560768  NM_001083831.1  NP_001077300.1 
fruit fly
(Drosophila melanogaster)
Insecta CG38941 CG3894 53.23(n)
41.53(a)
  37959  NM_138119.6  NP_611963.5 


ENSEMBL Gene Tree for NEURL2 (if available)
TreeFam Gene Tree for NEURL2 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for NEURL2 gene
NEURL42  ENSG000002619152  
1 SIMAP similar gene for NEURL2 using alignment to 2 protein entries:     NEUL2_HUMAN (see all proteins):
NEURL4

NEURL2 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

3 SNPs in NEURL2 are shown    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 20 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
VAR_0520334
----see VAR_0520332 E K mis40--------
rs1997859911,2
C--44518247(+) TCTCT-/CTTTCTT 1 -- int10--------
rs106391821,2
C--44518258(+) CTCTC-/TCTT  
        
TCttt
1 -- int1 trp30--------

HapMap Linkage Disequilibrium report for NEURL2 (44517264 - 44519926 bp)

Structural Variations
     Database of Genomic Variants (DGV) 4 variations for NEURL2:    About this table     
Variant IDTypeSubtypePubMed ID
nsv833991CNV Loss17160897
nsv833990CNV Loss17160897
nsv517296CNV Loss19592680
nsv482069CNV Gain20164927

SABiosciences Cancer Mutation PCR Assays
SeqTarget long-range PCR primers for resequencing NEURL2
DNA2.0 Custom Variant and Variant Library Synthesis for NEURL2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

NEURL2 for disorders           About MalaCards
OMIM gene information: 608597    OMIM disorders: --


NEURL2 for disorders           About GeneDecksing

Genetic Association Database (GAD): NEURL2
Human Genome Epidemiology (HuGE) Navigator: NEURL2 (1 document)

Export disorders for NEURL2 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for NEURL2 gene integrated from 9 sources:
(articles sorted by number of sources associating them with NEURL2)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Candidate-gene testing for orphan limb-girdle muscula r dystrophies. (PubMed id 19472918)1, 4 Aurino S....Nigro V. (2008)
  2. Ozz-E3, a muscle-specific ubiquitin ligase, regulates beta-catenin degradation during myogenesis. (PubMed id 14960280)1, 2 Nastasi T.... D'Azzo A. (2004)
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
  5. The SOCS box: a tale of destruction and degradation. (PubMed id 12076535)1, 3 Kile B.T....Hilton D.J. (2002)
  6. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
  7. Ozz; a new name on the long list of beta-catenin's nem eses. (PubMed id 14992713)1 Wu G....He X. (2004)
  8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 140825 HGNC: 16156 AceView: NEURL2 Ensembl:ENSG00000124257 euGenes: HUgn140825
ECgene: NEURL2 H-InvDB: NEURL2

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for NEURL2 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for NEURL2 gene:
Search GeneIP for patents involving NEURL2

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section

 
 EMD Millipore Custom Antibody & Bulk Services
 EMD Millipore Preclinical / Clinical Development Services
 EMD Millipore Immunoassay Services
 EMD Millipore Target Screening & Profiling Services

  
 Browse Antibodies   Browse Cell Culture Products  
 Browse ELISAs   Browse Flow Cytometry Kits  
 Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
 Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
 Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
 Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
 Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
 Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
 Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
 Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for NEURL2  
 Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for NEURL2  
 OriGene Custom Mass Spec   OriGene clones in human, mouse for NEURL2  
 OriGene qSTAR qPCR primer pairs in human, mouse for NEURL2   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
 OriGene ORF clones in mouse, rat for NEURL2   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for NEURL2   OriGene Custom Protein Services for NEURL2  

 
 
 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NEURL2
 QIAGEN SeqTarget long-range PCR primers for resequencing NEURL2
 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NEURL2
 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NEURL2
 QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NEURL2
 QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NEURL2
 GenScript Custom Purified and Recombinant Proteins Services for NEURL2 GenScript cDNA clones with any tag delivered in your preferred vector for NEURL2
 GenScript Custom Assay Services for NEURL2 GenScript Custom Superior Antibodies Services for NEURL2
 GenScript Custom overexpressing Cell Line Services for NEURL2 CloneReady with Over 120,000 Genes
 Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
 Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
 Custom Peptide Services
 Search for Antibodies & Assays

 Regulatory tfbs in NEURL2 promoter
 Search Chromatin IP Primers for NEURL2
 RT2 qPCR Primer Assay in human, mouse, rat NEURL2
 GNC Network for NEURL2
 SABiosciences Custom PCR Arrays for NEURL2
 Search Tocris compounds for NEURL2 (NEUL2)
 Browse Sino Biological Proteins and Antibodies
 Browse Sino Biological Cell Lysates
 Browse Sino Biological cDNA Clones
 4000+ Proteins
 Search Sino Biological for antibodies, proteins & pathways
 Protein Production Services
 Transfection Reagents
 Protein A/G/L resins
 Isotyping reagents
 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
 Novus Tissue Slides
 NEURL2 antibodies
 NEURL2 proteins
 NEURL2 lysates
 Search for Antibodies for NEURL2 at Abcam
 See all of Abcam's Antibodies, Kits and Proteins for NEURL2
 Custom Antibody / Protein Production Service
 Bulk Purchasing
 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins




 Proteins for NEURL2
 Antibodies for NEURL2
 ELISAs for NEURL2
 CLIAs for NEURL2
 Search LifeMap BioReagents cell lines for NEURL2
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NEURL2
 Browse SwitchGear 3'UTR luciferase reporter plasmids for NEURL2
 SwitchGear Promoter luciferase reporter plasmids for NEURL2
 Search ThermoFisher Antibodies for NEURL2
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NEURL2
 inGenious Targeting Laboratory - Custom generated mouse model solutions for NEURL2
 inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for NEURL2
Customized:
 lentivirus for stable overexpression of NEURL2
 lentivirus expression plasmids for stable overexpression of NEURL2
 adenovirus for overexpression of NEURL2
 LSBio Antibodies in human, mouse, rat for NEURL2
Customized transgenic rodents for:
 Humanization
 Biomarker expression
 Off-target effect monitoring
 Translational medicine
 Tissue-specific gene expresssion
 Time-controlled gene expresssion
       
GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

View Random Gene

Category
(GIFtS: 73)
transforming growth factor, beta 1
GIFtS Group
The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes      Disease genes      NEURL2 gene at Home site.
hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4