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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NEURL1B Gene

protein-coding   GIFtS: 40
GCID: GC05P172068

neuralized homolog 1B (Drosophila)
  Search for NEURL1B
in
MalaCards
our new
 Human Malady Compendium 
Biological research products
for NEURL1B    

Aliases
for NEURL1B gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Neuralized Homolog 1B (Drosophila)1 2     HNeur21
Neuralized-Like Protein 1B2 3     Neur21
Neuralized-Like Protein 32 3     Neuralized 2 Alternative Protein2
NEURL32 3     Neuralized-23
DKFZP761M15111     EC 6.3.2.-3
Neur21     NEUR23
E3 Ubiquitin-Protein Ligase NEURL1B2     Neuralized-23
E3 Ubiquitin-Protein Ligase NEURL32     

External Ids:    HGNC: 354221   Entrez Gene: 544922   Ensembl: ENSG000002143577   UniProtKB: A8MQ273   

Export aliases for NEURL1B gene to outside databases

Previous GC identifers: GC05P172002 GC05P167163


Summaries
for NEURL1B gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: NEU1B_HUMAN, A8MQ27
Function: E3 ubiquitin-protein ligase involved in regulation of the Notch pathway through influencing the stability and
activity of several Notch ligands




Genomic Views
for NEURL1B gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.1  NT_023133.13  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NEURL1B gene promoter:
         Pax-5   CUTL1   Meis-1b   HEN1   AREB6   SRY   STAT3   Meis-1a   NF-kappaB1   Meis-1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for NEURL1B

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NEURL1B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q35.1   Ensembl cytogenetic band:  5q35.1   HGNC cytogenetic band: 5q35.1

NEURL1B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NEURL1B gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P172068:  view genomic region     (about GC identifiers)

Start:
 172,068,269 bp from pter      End:
 172,118,543 bp from pter
Size:
 50,275 bases      Orientation:
 plus strand

Proteins
for NEURL1B gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: NEU1B_HUMAN, A8MQ27 (See protein sequence)
Recommended Name: E3 ubiquitin-protein ligase NEURL1B  
Size: 555 amino acids; 59270 Da
Subunit: Interacts with JAG1, DLL1 and DLL4
Subcellular location: Cytoplasm
Secondary accessions: C9DQJ5 C9DQJ6 C9DQJ7
Alternative splicing: 3 isoforms:  A8MQ27-1   A8MQ27-2   A8MQ27-3   

Explore the universe of human proteins at neXtProt for NEURL1B: NX_A8MQ27

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_A8MQ27

    • NEURL1B Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_001136123.1  
    ENSEMBL proteins: 
     ENSP00000429797   ENSP00000430001   ENSP00000358815  
    Reactome Protein details: A8MQ27
    Human Recombinant Protein Products: 
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    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: NEURL1B
    OriGene Custom Protein Services for NEURL1B 
    GenScript Custom Purified and Recombinant Proteins Services for NEURL1B
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for NEURL1B

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--


    NEURL1B for ontologies           About GeneDecksing



    NEURL1B Antibody Products: 
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    ThermoFisher Antibody for NEURL1B

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    Uscn ELISAs and CLIAs for NEURL1B

    Protein Domains /
    Families
    for NEURL1B gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    NEURL1B for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR001841 Znf_RING
     IPR006573 Neu_Z
     IPR013083 Znf_RING/FYVE/PHD

    Graphical View of Domain Structure for InterPro Entry A8MQ27

    ProtoNet protein and cluster: A8MQ27

    UniProtKB/Swiss-Prot: NEU1B_HUMAN, A8MQ27
    Similarity: Contains 2 NHR (neuralized homology repeat) domains
    Similarity: Contains 1 RING-type zinc finger


    Function
    for NEURL1B gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: NEU1B_HUMAN, A8MQ27
    Function: E3 ubiquitin-protein ligase involved in regulation of the Notch pathway through influencing the stability and
    activity of several Notch ligands

    Enzyme Number (IUBMB): EC 6.3.2.-1

    miRNA
    Products:            		Browse 3'-UTR reporter clones for miRNA target validation
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NEURL1B
    8/104 QIAGEN miScript miRNA Assays for microRNAs that regulate NEURL1B (see all 104):
    hsa-miR-3678-3p hsa-miR-3607-3p hsa-miR-106a hsa-miR-15a hsa-miR-1224-3p hsa-miR-128 hsa-miR-30d hsa-miR-519a
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NEURL1B (see all 4)
    OriGene shRNA RFP: NEURL1B
    OriGene siRNA: NEURL1B
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NEURL1B

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for NEURL1B

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NEURL1B (see all 2)
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NEURL1B
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    Cell Line
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    Search LifeMap BioReagents cell lines for NEURL1B

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NEURL1B

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008270zinc ion binding IEA--
    GO:0016874ligase activity IEA--


    NEURL1B for ontologies           About GeneDecksing



    Pathways & Interactions
    for NEURL1B gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Signaling by NOTCH1 t(7 9)(NOTCH1:M1580_K2555) Translocation Mutant
    8/10 pathways (see all 10)
    		Signaling by NOTCH1 PEST Domain Mutants in Cancer1.00
    		Signaling by NOTCH11.00
    		Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer1.00
    		Signaling by NOTCH1 t(7 9)(NOTCH1:M1580_K2555) Translocation Mutant1.00
    		Signaling by NOTCH1 in Cancer1.00
    		Constitutive Signaling by NOTCH1 PEST Domain Mutants0.79
    		Signaling by NOTCH1 HD Domain Mutants in Cancer1.00
    		Signaling by NOTCH0.77
    2NOTCH2 Activation and Transmission of Signal to the Nucleus
    		NOTCH2 Activation and Transmission of Signal to the Nucleus1.00
    		Constitutive Signaling by NOTCH1 HD Domain Mutants0.62
    		Signaling by NOTCH21.00
    		Activated NOTCH1 Transmits Signal to the Nucleus0.58
    3Disease
    		Disease1.00
    4Signaling by GPCR
    		Signal Transduction0.56

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5/16        Reactome Pathways for NEURL1B (see all 16)
        Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
    FBXW7 Mutants and NOTCH1 in Cancer
    Signaling by NOTCH1 HD Domain Mutants in Cancer
    Signaling by NOTCH1 in Cancer
    Disease


    UniProtKB/Swiss-Prot: NEU1B_HUMAN, A8MQ27
    Pathway: Protein modification; protein ubiquitination


    NEURL1B for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NEURL1B

    5/6 Interacting proteins for NEURL1B (A8MQ273) via UniProtKB, MINT, STRING, and/or I2D (see all 6)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    SSBP054553I2D: score=3 
    DLL1O005483I2D: score=2 
    JAG2Q9Y2193I2D: score=1 
    NOTCH2Q047213I2D: score=1 
    UBE2D2P628373I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007219Notch signaling pathway IEA--
    GO:0016567protein ubiquitination IEA--


    NEURL1B for ontologies           About GeneDecksing



    Drugs & Compounds
    for NEURL1B gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NEURL1B
    Search CenterWatch for drugs/clinical trials and news about NEURL1B / NEU1B 

    Transcripts
    for NEURL1B gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for NEURL1B gene: 
    NM_001142651.1  

    Unigene Cluster for NEURL1B:

    Neuralized homolog 1B (Drosophila)
    Hs.91521  [show with all ESTs]
    Unigene Representative Sequence: NM_001142651
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000520919 ENST00000522853 ENST00000369800(uc003mbt.3 uc021yhs.1 uc021yht.1)


    miRNA
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    8/104 QIAGEN miScript miRNA Assays for microRNAs that regulate NEURL1B (see all 104):
    hsa-miR-3678-3p hsa-miR-3607-3p hsa-miR-106a hsa-miR-15a hsa-miR-1224-3p hsa-miR-128 hsa-miR-30d hsa-miR-519a
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NEURL1B (see all 4)
    OriGene shRNA RFP: NEURL1B
    OriGene siRNA: NEURL1B
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NEURL1B
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NEURL1B (see all 2)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NEURL1B
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: NEURL1B (NM_001142651)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NEURL1B
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat NEURL1B 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NEURL1B
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NEURL1B
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NEURL1B
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NEURL1B

    Additional cDNA sequence: 

    AK026748.1 AK091605.1 AK096661.1 AK126311.1 AL137347.1 GQ414757.1 GQ414758.1 GQ414759.1 

    5 DOTS entries:

    DT.115529  DT.91966891  DT.100755393  DT.75104332  DT.120796631 

    GeneLoc Exon Structure


    Expression
    for NEURL1B gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NEURL1B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TCTTCTTTTT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    NEURL1B expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 2 LifeMap Cells 
    NameCategory
    PureStem™ endothelial progenitor 30-MV2-12 (Embryonic Progenitor Cell)Blood, Endothelium
    PureStem™ endothelial Progenitor 30-SM2-3 (Embryonic Progenitor Cell)Blood, Endothelium
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See NEURL1B Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NEURL1B

    SOURCE GeneReport for Unigene cluster: Hs.91521

    UniProtKB/Swiss-Prot: NEU1B_HUMAN, A8MQ27
    Tissue specificity: Highest expression in brain, prostate and small intestine. In the brain the levels are higher in
    fetal than in adult stage. In the adult brain the highest levels are detected in the olfactory system, cerebellar
    cortex, optic nerve and the frontal lobe

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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NEURL1B

    Orthologs
    for NEURL1B gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for NEURL1B gene from 6/19 species (see all 19)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Neurl1b1 , 5 neuralized homolog 1b (Drosophila)1, 5 87.06(n)1
    92.67(a)1    		   17 (13.18 cM)5
    2400551  NM_001081656.21  NP_001075125.11 
     264149655 
    chicken
    (Gallus gallus)    		 Aves NEURL1B1 neuralized homolog 1B (Drosophila) 70.78(n)
    70.6(a)    		   427626  XM_425198.3  XP_425198.2 
    lizard
    (Anolis carolinensis)    		 Reptilia NEURL1B6
    		 --
    		 66(a)
    		 1 ↔ 1
    		 2(123986784-123996086)
    zebrafish
    (Danio rerio)    		 Actinopterygii zgc:1104266
    		 zgc:110426
    		 63(a)
    		 1 ↔ 1
    		 14(19564437-19599512)
    fruit fly
    (Drosophila melanogaster)    		 Insecta neur1 neuralized 48.28(n)
    35.6(a)    		   41085  NM_169257.1  NP_731311.1 
    worm
    (Caenorhabditis elegans)    		 Secernentea F10D7.51 Protein F10D7.5 41.75(n)
    33.41(a)    		   181767  NM_078417.4  NP_510818.3 


    ENSEMBL Gene Tree for NEURL1B (if available)
    TreeFam Gene Tree for NEURL1B (if available) 

    Paralogs
    for NEURL1B gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NEURL1B gene
    NEURL22  NEURL2  
    3 SIMAP similar genes for NEURL1B using alignment to 1 protein entry:     NEU1B_HUMAN:
    NEURL3    MDM2    NEURL

    NEURL1B for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for NEURL1B
    PGOHUM00000250440


    Genomic Variants
    for NEURL1B gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/827 NCBI SNPs in NEURL1B are shown (see all 827)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 5 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs286382201,2
    		--167185381(+) GCTCAC/TGCCTG 1 -- us2k11Minor allele frequency- T:0.50CSA 2
    rs563875711,2
    		--167185547(+) TGAGGC/TAGGAG 1 -- us2k10--------
    rs760189651,2
    		C,F,--167185872(+) GGTCTT/CTCATG 1 -- us2k11Minor allele frequency- C:0.25WA 118
    rs773648861,2
    		F,--167186116(+) GCCCTC/TGATGG 1 -- us2k11Minor allele frequency- T:0.08NA 120
    rs773319441,2
    		F,--167186448(+) TGTAGG/ATGAAG 1 -- us2k11Minor allele frequency- A:0.03NA 120
    rs728099101,2
    		C,F,--167186576(+) TGCAGA/GGACAG 1 -- us2k11Minor allele frequency- G:0.04NA 120
    rs771735571,2
    		--167186585(+) AGGGAA/GCAAAA 1 -- us2k10--------
    rs1130165101,2
    		--167186741(+) CAGGGC/ACCTTG 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs773601311,2
    		F,--167187399(+) GTGTCG/ATGCAC 1 -- nc-transcript-variant1Minor allele frequency- A:0.05WA 118
    rs789467481,2
    		C,F,--167187420(+) TGAGCG/ATGGAC 1 -- nc-transcript-variant1Minor allele frequency- A:0.25WA 118

    HapMap Linkage Disequilibrium report for NEURL1B (172068269 - 172118543 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 8 variations for NEURL1B
         8 CNVs: 53358 2608 81124 8500 9524 37741 3587 8501

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NEURL1B
    DNA2.0 Custom Variant and Variant Library Synthesis for NEURL1B

    Disorders / Diseases
    for NEURL1B gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    		   --

    Publications
    for NEURL1B gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NEURL1B gene integrated from 9 sources:
    (articles sorted by number of sources associating them with NEURL1B)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Neuralized-2: Expression in human and rodents and interaction with Delta-like ligands. (PubMed id 19723503)1, 2 Rullinkov G....Timmusk T. (2009)
    2. Neuralized-2 regulates a Notch ligand in cooperation with Mind bomb-1. (PubMed id 17003037)1, 3 Song R....Kong Y.Y. (2006)
    3. The DNA sequence and comparative analysis of human chromosome 5. (PubMed id 15372022)1, 2 Schmutz J.... Rubin E.M. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)

    External Searches for NEURL1B gene

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    Genome Databases showing NEURL1B gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 54492 HGNC: 35422 Ensembl:ENSG00000214357 euGenes: HUgn54492 ECgene: NEURL1B
    H-InvDB: NEURL1B

    Other Databases showing NEURL1B gene

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    Specialized Databases showing NEURL1B gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NEURL1B Pharmacogenomics, SNPs, Pathways

    Intellectual Property
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    		Patent Information for NEURL1B gene:
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