Aliases for NET1 Gene
Aliases for NET1 Gene
External Ids for NET1 Gene
- HGNC: 14592
- Entrez Gene: 10276
- Ensembl: ENSG00000173848
- OMIM: 606450
- UniProtKB: Q7Z628
Previous GeneCards Identifiers for NET1 Gene
- GC10M005513
- GC10P005428
- GC10P005554
- GC10P005408
Summaries for NET1 Gene
-
This gene is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation. Pseudogenes of this gene are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]
GeneCards Summary for NET1 Gene
NET1 (Neuroepithelial Cell Transforming 1) is a Protein Coding gene. Diseases associated with NET1 include Skin Squamous Cell Carcinoma and Breast Cancer. Among its related pathways are p75 NTR receptor-mediated signalling and fMLP Pathway. Gene Ontology (GO) annotations related to this gene include guanyl-nucleotide exchange factor activity and GTP-Rho binding. An important paralog of this gene is ARHGEF3.
UniProtKB/Swiss-Prot for NET1 Gene
-
Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NET1 Gene
Genomics for NET1 Gene
GeneHancer (GH) Regulatory Elements for NET1 Gene
Promoters and enhancers for NET1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around NET1 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for NET1 Gene
Genomic Locations for NET1 Gene
- chr10:5,412,551-5,459,056
- (GRCh38/hg38)
- Size:
- 46,506 bases
- Orientation:
- Plus strand
- chr10:5,454,514-5,500,426
- (GRCh37/hg19)
Genomic View for NET1 Gene
Genes around NET1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 10p15.1 by Ensembl
- 10p15.1 by Entrez Gene
- 10p15.1 by HGNC
NET1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for NET1 Gene
Proteins for NET1 Gene
-
Protein details for NET1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q7Z628-ARHG8_HUMAN
- Recommended name:
- Neuroepithelial cell-transforming gene 1 protein
- Protein Accession:
- Q7Z628
- Q12773
- Q96D82
- Q99903
- Q9UEN6
Protein attributes for NET1 Gene
- Size:
- 596 amino acids
- Molecular mass:
- 67740 Da
- Quaternary structure:
-
- Interacts with RHOA in its GTP- and GDP-bound states, and with CDC42 in its GTP-bound state. Interacts with the PDZ 1 domain of BAIAP1 (By similarity).
- SequenceCaution:
-
- Sequence=AAB08847.1; Type=Frameshift; Positions=586; Evidence={ECO:0000305}; Sequence=AAB37683.1; Type=Frameshift; Positions=15, 33; Evidence={ECO:0000305}; Sequence=CAA08974.1; Type=Frameshift; Positions=8, 55, 59, 70, 586; Evidence={ECO:0000305};
Protein Expression for NET1 Gene
Post-translational modifications for NET1 Gene
- Ubiquitination at isoforms=2194, isoforms=2301, and isoforms=2489
Other Protein References for NET1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for NET1
-
Abcam antibodies for NET1
-
Cloud-Clone Corp. Antibodies for NET1
- Invitrogen Antibodies for NET1
- antibodies-online: Search results for 123 available NET1 Antibodies ranked by validation data
- Compare Top NET1 Antibodies
-
Recommended
- 60 WB Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 8 IHC (p) Antibodies (anti-human)
- 3 IHC Antibodies (anti-human)
- 2 DB Antibodies (anti-human)
- 1 ICC Antibody (anti-human)
- 16 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 1 IHC Antibody (anti-rat)
- 26 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 1 IHC Antibody (anti-mouse)
- GeneTex NET1 antibody for NET1
-
Santa Cruz Biotechnology (SCBT) Antibodies for NET1
Protein Products
-
OriGene Purified Proteins for NET1
- Search Origene for MassSpec and Protein Over-expression Lysates for NET1
- Origene Custom Protein Services for NET1
-
Cloud-Clone Corp. Proteins for NET1
- Search GeneTex for Proteins for NET1
-
Abcam proteins for NET1
Assay Products
-
Cloud-Clone Corp. Assay Kits for NET1
No data available for DME Specific Peptides for NET1 Gene
Domains & Families for NET1 Gene
Gene Families for NET1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for NET1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for NET1 Gene
- GenScript: Design optimal peptide antigens:
-
- Rho guanine nucleotide exchange factor 8 (ARHG8_HUMAN)
- cDNA FLJ53956, highly similar to Neuroepithelial cell-transforming gene 1 protein (B4E1Y1_HUMAN)
- cDNA FLJ50843, highly similar to Neuroepithelial cell-transforming gene 1 protein (Q5SQI5_HUMAN)
- cDNA, FLJ96638, Homo sapiens neuroepithelial cell transforming gene 1 (NET1), mRNA (Q5SQI7_HUMAN)
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for NET1 Gene
Function for NET1 Gene
Molecular function for NET1 Gene
- UniProtKB/Swiss-Prot Function:
- Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death.
- UniProtKB/Swiss-Prot Induction:
- By TGFB1. Up-regulated by DNA damaging agents like H(2)O(2) or ionizing radiation (IR).
Phenotypes From GWAS Catalog for NET1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005085 | guanyl-nucleotide exchange factor activity | TAS | -- |
| GO:0005089 | Rho guanyl-nucleotide exchange factor activity | TAS | -- |
| GO:0005515 | protein binding | IPI | 24550280 |
| GO:0017049 | GTP-Rho binding | IEA | -- |
Phenotypes for NET1 Gene
- MGI mutant phenotypes for NET1:
- inferred from 3 alleles
- GenomeRNAi human phenotypes for NET1:
-
- Increased vaccinia virus (VACV) infection
- Synthetic lethal with Ras
- Increased transferrin (TF) endocytosis
- Decreased IL-8 secretion
- Decreased focal adhesion (FA) area, decreased FA length, decreased FA mean intensity, increased number of small and round FAs, increased FA abundance
- Increased epidermal growth factor receptor (EGFR) surface abundance
- Upregulation of Wnt/beta-catenin pathway after WNT3A stimulation
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for NET1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for NET1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for NET1 gene
- Search ViGene Biosciences for NET1
CRISPR Products
-
OriGene CRISPR knockouts for NET1
- genomics-online: gRNA clones - Search results for 157 available NET1 gene related products
- Overview of 157 available NET1 gene related products
- Applied Biological Materials CRISPR for NET1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for NET1
- GenScript: Design CRISPR guide RNA sequences for NET1
miRNA for NET1 Gene
- miRTarBase miRNAs that target NET1
miRNA Products
- Search ViGene Biosciences for NET1
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for NET1
- Browse OriGene Inhibitory RNA Products For NET1
- genomics-online: shRNA clones - Search results for 157 available NET1 gene related products
- Overview of 157 available NET1 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for NET1 gene
Clone Products
- Sino Biological Human cDNA Clone for NET1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for NET1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NET1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for NET1
- Applied Biological Materials Clones for NET1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for NET1
-
ViGene Biosciences adenoviral particle packaged cDNA for NET1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for NET1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for NET1 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for NET1 Gene
Localization for NET1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for NET1 Gene
- Cytoplasm. Nucleus.
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| nucleus | 4 |
| plasma membrane | 2 |
| cytoskeleton | 1 |
- Nucleus (2)
- Vesicles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005622 | intracellular | IEA | -- |
| GO:0005634 | nucleus | IEA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005829 | cytosol | TAS | -- |
| GO:0005886 | plasma membrane | IEA | -- |
Pathways & Interactions for NET1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | p75 NTR receptor-mediated signalling |
.36
|
|
| 2 | GPCR Pathway |
.73
.62
|
|
| 3 | G-AlphaQ Signaling | ||
| 4 | Signaling by GPCR | ||
| 5 | fMLP Pathway |
.39
|
|
Pathways by source for NET1 Gene
2 BioSystems pathways for NET1 Gene
1 GeneGo (Thomson Reuters) pathway for NET1 Gene
21 Qiagen pathways for NET1 Gene
Interacting Proteins for NET1 Gene
Selected Interacting proteins:
ENSP00000347134
Q7Z628-ARHG8_HUMAN
for NET1 Gene via
STRING
UniProtKB
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001558 | regulation of cell growth | NAS | 8649828 |
| GO:0007165 | signal transduction | TAS | 8649828 |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | -- |
| GO:0035023 | regulation of Rho protein signal transduction | IEA | -- |
| GO:0035556 | intracellular signal transduction | IEA | -- |
No data available for SIGNOR curated interactions for NET1 Gene
Transcripts for NET1 Gene
mRNA/cDNA for NET1 Gene
- (2) REFSEQ mRNAs :
- (13) Additional mRNA sequences :
- (386) Selected AceView cDNA sequences:
- (6) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for NET1 Gene
- Neuroepithelial cell transforming 1:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for NET1
- genomics-online: gRNA clones - Search results for 157 available NET1 gene related products
- Overview of 157 available NET1 gene related products
- Applied Biological Materials CRISPR for NET1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for NET1
- GenScript: Design CRISPR guide RNA sequences for NET1
miRNA Products
- Search ViGene Biosciences for NET1
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for NET1
- Browse OriGene Inhibitory RNA Products For NET1
- genomics-online: shRNA clones - Search results for 157 available NET1 gene related products
- Overview of 157 available NET1 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for NET1 gene
Clone Products
- Sino Biological Human cDNA Clone for NET1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for NET1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NET1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for NET1
- Applied Biological Materials Clones for NET1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | ^ | 9a | · | 9b | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13a | · | 13b | ^ | 14 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP8: | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP10: |
Expression for NET1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Limb (Muscoskeletal System)
- Limb Bud Mesenchyme Cells Limb Bud
-
Mesoderm (Gastrulation Derivatives)
- Limb Bud Mesenchyme Cells Limb Bud
- Intestine (Gastrointestinal Tract)
-
Colon (Gastrointestinal Tract)
-
Placenta (Extraembryonic Tissues)
-
Esophagus (Gastrointestinal Tract)
-
Stomach (Gastrointestinal Tract)
This gene is overexpressed in Serum (56.5) and Cerebrospinal fluid (12.5).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for NET1 Gene
NURSA nuclear receptor signaling pathways regulating expression of NET1 Gene:
NET1SOURCE GeneReport for Unigene cluster for NET1 Gene:
Hs.25155mRNA Expression by UniProt/SwissProt for NET1 Gene:
Q7Z628-ARHG8_HUMAN
Tissue specificity:
Widely expressed.
Evidence on tissue expression from TISSUES for NET1 Gene
- Nervous system(4.3)
- Eye(4.1)
Primer Products
-
OriGene qPCR primer pairs for NET1
-
OriGene qPCR primer pairs and template standards for NET1
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for NET1 Gene
Orthologs for NET1 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | NET1 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | NET1 34 33 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Net1 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Net1 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | -- 34 |
|
OneToMany | |
| -- 34 |
|
OneToMany | |||
| -- 34 |
|
OneToMany | |||
| cow (Bos Taurus) |
Mammalia | NET1 33 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | NET1 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | NET1 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | NET1 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | net1 33 |
|
||
| Str.5900 33 |
|
||||
| zebrafish (Danio rerio) |
Actinopterygii | net1 33 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | Gef64C 34 |
|
ManyToMany | |
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | ROM1 34 36 |
|
ManyToMany | |
| ROM2 34 |
|
ManyToMany | |||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany |
- Species where no ortholog for NET1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for NET1 Gene
Paralogs for NET1 Gene
(8) SIMAP similar genes for NET1 Gene using alignment to 5 proteins:
Pseudogenes.org Pseudogenes for NET1 Gene
Variants for NET1 Gene
| SNP ID | Clin | Chr 10 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs796052153 | likely-benign, Long QT syndrome | 5,452,909(+) | C/T | coding_sequence_variant, missense_variant, non_coding_transcript_variant | |
| VAR_035972 | A breast cancer sample | p.Asp202Asn | |||
| rs869312683 | uncertain-significance, not specified | 5,454,335(+) | A/G | coding_sequence_variant, missense_variant, non_coding_transcript_variant | |
| rs1000020385 | -- | 5,418,673(+) | C/T | genic_upstream_transcript_variant, intron_variant | |
| rs1000049855 | -- | 5,418,920(+) | A/T | genic_upstream_transcript_variant, intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2731718 | CNV | deletion | 23290073 |
| esv3622229 | CNV | loss | 21293372 |
| nsv1045141 | CNV | gain | 25217958 |
| nsv549886 | CNV | loss | 21841781 |
| nsv831774 | CNV | gain | 17160897 |
Residual Variation Intolerance Score:
14.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.27;
52.88% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for NET1 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NET1 Gene
Disorders for NET1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| skin squamous cell carcinoma |
|
|
| breast cancer |
|
|
Search NET1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for NET1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for NET1 Gene
Publications for NET1 Gene
- Isolation of a novel oncogene, NET1, from neuroepithelioma cells by expression cDNA cloning. (PMID: 8649828) Chan AM … Miki T (Oncogene 1996) 2 3 4 22 58
- The nuclear guanine nucleotide exchange factors Ect2 and Net1 regulate RhoB-mediated cell death after DNA damage. (PMID: 21373644) Srougi MC … Burridge K (PloS one 2011) 3 4 58
- Coexpression of alpha6beta4 integrin and guanine nucleotide exchange factor Net1 identifies node-positive breast cancer patients at high risk for distant metastasis. (PMID: 19124484) Gilcrease MZ … Frost JA (Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009) 3 22 58
- Interaction of the RhoA exchange factor Net1 with discs large homolog 1 protects it from proteasome-mediated degradation and potentiates Net1 activity. (PMID: 19586902) Carr HS … Frost JA (The Journal of biological chemistry 2009) 3 22 58
- Expression and clinical significance of NET-1 and PCNA in hepatocellular carcinoma. (PMID: 18214716) Shen SQ … Nakao A (Medical oncology (Northwood, London, England) 2008) 3 22 58
Products for NET1 Gene
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- CloneReady with Over 120,000 Genes
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- Cloud-Clone Corp. Antibodies for NET1
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- Browse Knockouts at Cloud-Clone Corp.
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- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
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- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for NET1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for NET1
- VectorBuilder custom plasmid, inducible vectors for NET1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NET1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for NET1
- antibodies-online: Search results for 123 available NET1 Antibodies ranked by validation data
- Compare Top NET1 Antibodies
- Recommended
- 60 WB Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 8 IHC (p) Antibodies (anti-human)
- 3 IHC Antibodies (anti-human)
- 2 DB Antibodies (anti-human)
- 1 ICC Antibody (anti-human)
- 16 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 1 IHC Antibody (anti-rat)
- 26 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 1 IHC Antibody (anti-mouse)
- antibodies-online: Search results for 4 available NET1 Elisa Kits ranked by validation data
- Compare Top NET1 Elisa Kits
- Recommended
- antibodies-online: Search results for 4 available NET1 Proteins ranked by validation data
- Compare Top NET1 Proteins
- GeneTex NET1 antibody for NET1
- Search GeneTex for Proteins for NET1
- ViGene Biosciences adenoviral particle packaged cDNA for NET1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for NET1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for NET1 gene
- Search ViGene Biosciences for NET1
- Santa Cruz Biotechnology (SCBT) Antibodies for NET1
- Search Santa Cruz Biotechnology (SCBT) for NET1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for NET1
- Horizon Cell Lines for NET1
- genomics-online: cdna clones - Search results for 157 available NET1 gene related products
- Overview of 157 available NET1 gene related products
- orf clones - Search results for 157 available NET1 gene related products
- Overview of 157 available NET1 gene related products
- genomics-online: gRNA clones - Search results for 157 available NET1 gene related products
- Overview of 157 available NET1 gene related products
- genomics-online: primer clones - Search results for 157 available NET1 gene related products
- Overview of 157 available NET1 gene related products
- genomics-online: shRNA clones - Search results for 157 available NET1 gene related products
- Overview of 157 available NET1 gene related products
Sources for NET1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew