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Aliases for NEPNP Gene

Aliases for NEPNP Gene

  • Nephrocan, Pseudogene 2 3 5
  • Asporin Pseudogene 3
  • NEPN Pseudogene 3
  • NEPN 3
  • NPN 3

External Ids for NEPNP Gene

Previous GeneCards Identifiers for NEPNP Gene

  • GC06P117924

Summaries for NEPNP Gene

Entrez Gene Summary for NEPNP Gene

  • Nephrocan is a secreted glycoprotein that acts as an inhibitor of the transforming growth factor-beta signaling pathway. This gene has been inactivated by mutation and is nonfunctional in humans. [provided by RefSeq, May 2010]

GeneCards Summary for NEPNP Gene

NEPNP (Nephrocan, Pseudogene) is a Pseudogene.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NEPNP Gene

Genomics for NEPNP Gene

Regulatory Elements for NEPNP Gene

Enhancers for NEPNP Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06G117165 1.2 Ensembl ENCODE dbSUPER 4.6 -434.8 -434819 4.9 CTCF PKNOX1 FEZF1 ZIC2 HIC1 ZNF366 ZNF600 FOS BHLHE40 ZEB2 VGLL2 NEPNP GC06M117235 RNA5SP214
GH06G117600 1.1 ENCODE 0.7 -0.4 -360 3.3 HDGF PKNOX1 MLX CREB3L1 AGO1 ZFP64 WRNIP1 ARID4B SIN3A DMAP1 NUS1 DCBLD1 GOPC NEPNP
GH06G117605 0.9 ENCODE 0.7 +2.5 2455 0.2 HDGF PKNOX1 FOXA2 CBX3 RB1 WRNIP1 ARID4B RAD21 ZNF143 RELB NEPNP PIR51319
GH06G117615 1.4 FANTOM5 Ensembl ENCODE 0.4 +13.7 13699 2.6 CTCF NFIB TEAD4 BACH1 EBF1 ZIC2 RELA GLIS2 ZFHX2 SCRT2 DCBLD1 NUS1 ENSG00000226181 RNU6-253P GOPC PIR51319 NEPNP
GH06G117607 0.5 Ensembl 0.7 +4.8 4773 0.6 IKZF1 RELB IKZF2 NUS1 ENSG00000226181 DCBLD1 NEPNP PIR51319
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around NEPNP on UCSC Golden Path with GeneCards custom track

Promoters for NEPNP Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000201754 -1028 2601 HDGF PKNOX1 MLX CREB3L1 AGO1 ZFP64 WRNIP1 ARID4B SIN3A FEZF1

Genomic Location for NEPNP Gene

Chromosome:
6
Start:
117,602,928 bp from pter
End:
117,645,087 bp from pter
Size:
42,160 bases
Orientation:
Plus strand

Genomic View for NEPNP Gene

Genes around NEPNP on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NEPNP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NEPNP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NEPNP Gene

Proteins for NEPNP Gene

Post-translational modifications for NEPNP Gene

No Post-translational modifications

No data available for DME Specific Peptides for NEPNP Gene

Domains & Families for NEPNP Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for NEPNP Gene

Function for NEPNP Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NEPNP Gene

Localization for NEPNP Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for NEPNP Gene

Pathways & Interactions for NEPNP Gene

SuperPathways for NEPNP Gene

No Data Available

Interacting Proteins for NEPNP Gene

Gene Ontology (GO) - Biological Process for NEPNP Gene

None

No data available for Pathways by source and SIGNOR curated interactions for NEPNP Gene

Drugs & Compounds for NEPNP Gene

No Compound Related Data Available

Transcripts for NEPNP Gene

mRNA/cDNA for NEPNP Gene

(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for NEPNP Gene

No ASD Table

Relevant External Links for NEPNP Gene

GeneLoc Exon Structure for
NEPNP
ECgene alternative splicing isoforms for
NEPNP

Expression for NEPNP Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for NEPNP Gene

mRNA differential expression in normal tissues according to GTEx for NEPNP Gene

This gene is overexpressed in Testis (x4.3).

NURSA nuclear receptor signaling pathways regulating expression of NEPNP Gene:

NEPNP
genes like me logo Genes that share expression patterns with NEPNP: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NEPNP Gene

Orthologs for NEPNP Gene

Evolution for NEPNP Gene

ENSEMBL:
Gene Tree for NEPNP (if available)
TreeFam:
Gene Tree for NEPNP (if available)

No data available for Orthologs for NEPNP Gene

Paralogs for NEPNP Gene

No data available for Paralogs for NEPNP Gene

Variants for NEPNP Gene

Relevant External Links for NEPNP Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
NEPNP

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for NEPNP Gene

Disorders for NEPNP Gene

Relevant External Links for NEPNP

Genetic Association Database (GAD)
NEPNP

No disorders were found for NEPNP Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NEPNP Gene

Publications for NEPNP Gene

  1. Identification and analysis of unitary pseudogenes: historic and contemporary gene losses in humans and other primates. (PMID: 20210993) Zhang Z.D. … Gerstein M. (Genome Biol. 2010) 2 3 64
  2. Analysis of the Histone H3.1 Interactome: A Suitable Chaperone for the Right Event. (PMID: 26527279) Campos E.I. … Reinberg D. (Mol. Cell 2015) 3 64
  3. Comparative genomics search for losses of long-established genes on the human lineage. (PMID: 18085818) Zhu J. … Haussler D. (PLoS Comput. Biol. 2007) 3 64
  4. Genome-wide association with bone mass and geometry in the Framingham Heart Study. (PMID: 17903296) Kiel D.P. … Karasik D. (BMC Med. Genet. 2007) 46 64
  5. Nephrocan, a novel member of the small leucine-rich repeat protein family, is an inhibitor of transforming growth factor-beta signaling. (PMID: 16990280) Mochida Y. … Yamauchi M. (J. Biol. Chem. 2006) 3 64

Products for NEPNP Gene

Sources for NEPNP Gene

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