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Aliases for NEPNP Gene

Aliases for NEPNP Gene

  • Nephrocan, Pseudogene 2 3
  • Asporin Pseudogene 3
  • NEPN Pseudogene 3
  • NEPN 3
  • NPN 3

External Ids for NEPNP Gene

Summaries for NEPNP Gene

Entrez Gene Summary for NEPNP Gene

  • Nephrocan is a secreted glycoprotein that acts as an inhibitor of the transforming growth factor-beta signaling pathway. This gene has been inactivated by mutation and is nonfunctional in humans. [provided by RefSeq, May 2010]

GeneCards Summary for NEPNP Gene

NEPNP (Nephrocan, Pseudogene) is a Pseudogene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NEPNP Gene

Genomics for NEPNP Gene

Genomic Location for NEPNP Gene

Start:
117,602,928 bp from pter
End:
117,645,087 bp from pter
Size:
42,160 bases
Orientation:
Plus strand

Genomic View for NEPNP Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for NEPNP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NEPNP Gene

No data available for Regulatory Elements for NEPNP Gene

Proteins for NEPNP Gene

Post-translational modifications for NEPNP Gene

No Post-translational modifications

No data available for DME Specific Peptides for NEPNP Gene

Domains for NEPNP Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for NEPNP Gene

Function for NEPNP Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for NEPNP Gene

Localization for NEPNP Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for NEPNP Gene

Pathways for NEPNP Gene

SuperPathways for NEPNP Gene

No Data Available

Interacting Proteins for NEPNP Gene

Gene Ontology (GO) - Biological Process for NEPNP Gene

None

No data available for Pathways by source for NEPNP Gene

Transcripts for NEPNP Gene

mRNA/cDNA for NEPNP Gene

(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for NEPNP Gene

No ASD Table

Relevant External Links for NEPNP Gene

GeneLoc Exon Structure for
NEPNP
ECgene alternative splicing isoforms for
NEPNP

Expression for NEPNP Gene

mRNA expression in normal human tissues for NEPNP Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for NEPNP Gene

This gene is overexpressed in Testis (4.3).
genes like me logo Genes that share expressions with NEPNP: view

No data available for Protein expression and mRNA Expression by UniProt/SwissProt for NEPNP Gene

Orthologs for NEPNP Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for NEPNP Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Nepn 16
Species with no ortholog for NEPNP:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NEPNP Gene

ENSEMBL:
Gene Tree for NEPNP (if available)
TreeFam:
Gene Tree for NEPNP (if available)

Paralogs for NEPNP Gene

No data available for Paralogs for NEPNP Gene

Variants for NEPNP Gene

Relevant External Links for NEPNP Gene

HapMap Linkage Disequilibrium report
NEPNP

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for NEPNP Gene

Disorders for NEPNP Gene

Relevant External Links for NEPNP

Genetic Association Database (GAD)
NEPNP
genes like me logo Genes that share disorders with NEPNP: view

No data available for UniProtKB/Swiss-Prot for NEPNP Gene

Publications for NEPNP Gene

  1. Identification and analysis of unitary pseudogenes: historic and contemporary gene losses in humans and other primates. (PMID: 20210993) Zhang Z.D. … Gerstein M. (Genome Biol. 2010) 2 3
  2. Genome-wide association with bone mass and geometry in the Framingham Heart Study. (PMID: 17903296) Kiel D.P. … Karasik D. (BMC Med. Genet. 2007) 48
  3. Nephrocan, a novel member of the small leucine-rich repeat protein family, is an inhibitor of transforming growth factor-beta signaling. (PMID: 16990280) Mochida Y. … Yamauchi M. (J. Biol. Chem. 2006) 3
  4. Comparative genomics search for losses of long-established genes on the human lineage. (PMID: 18085818) Zhu J. … Haussler D. (PLoS Comput. Biol. 2007) 3

Products for NEPNP Gene

Sources for NEPNP Gene

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