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NEMF Gene

protein-coding   GIFtS: 46
GCID: GC14M050250

Nuclear Export Mediator Factor

(Previous name: serologically defined colon cancer antigen 1)
(Previous symbol: SDCCAG1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Nuclear Export Mediator Factor1 2
SDCCAG11 2 3 5
Serologically Defined Colon Cancer Antigen 11 2 3
Antigen NY-CO-12 3
NY-CO-12
Nuclear Export Mediator Factor NEMF2

External Ids:    HGNC: 106631   Entrez Gene: 91472   Ensembl: ENSG000001655257   OMIM: 6083785   UniProtKB: O605243   

Export aliases for NEMF gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for NEMF Gene:
NEMF (nuclear export mediator factor) is a protein-coding gene. Diseases associated with NEMF include lung cancer, and malaria.

UniProtKB/Swiss-Prot: NEMF_HUMAN, O60524
Function: Plays a role in nuclear export




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000014.9  NT_026437.13  NC_018925.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for NEMF
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): NEMF promoter sequence
   Search Chromatin IP Primers for NEMF

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NEMF


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q22   Ensembl cytogenetic band:  14q21.3   HGNC cytogenetic band: 14q21.3

NEMF Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NEMF gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M050250:  view genomic region     (about GC identifiers)

Start:
50,249,997 bp from pter      End:
50,319,921 bp from pter
Size:
69,925 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: NEMF_HUMAN, O60524 (See protein sequence)
Recommended Name: Nuclear export mediator factor NEMF  
Size: 1076 amino acids; 122954 Da
Subunit: Interacts (via its N-terminus) with XPO1 (By similarity)
Miscellaneous: Active in normal lung tissue, but is inactive in several lung cancer cell lines
Sequence caution: Sequence=AAC18036.1; Type=Frameshift; Positions=1065; Sequence=AAH06001.1; Type=Miscellaneous
discrepancy; Note=Contaminating sequence. Potential poly-A sequence; Sequence=AAH20794.2; Type=Erroneous
initiation; Note=Translation N-terminally extended; Sequence=AAH56687.1; Type=Miscellaneous discrepancy;
Note=Contaminating sequence. Potential poly-A sequence; Sequence=AAI07765.1; Type=Erroneous initiation;
Note=Translation N-terminally shortened; Sequence=BAG52763.1; Type=Erroneous initiation; Note=Translation
N-terminally extended; Sequence=BAG58070.1; Type=Erroneous translation; Note=Wrong choice of frame;
Sequence=BAG58070.1; Type=Frameshift; Positions=246, 1025; Sequence=BAG58070.1; Type=Miscellaneous discrepancy;
Note=Intron retention;
Secondary accessions: A0JLQ3 B3KSK1 B4DDL3 B4DHA9 B4E3F3 Q32Q66 Q8WW70 Q9NWG1
Alternative splicing: 5 isoforms:  O60524-1   O60524-2   O60524-3   O60524-4   O60524-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NEMF: NX_O60524

Explore proteomics data for NEMF at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys35
  • Modification sites at PhosphoSitePlus

  • See NEMF Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_004704.2  
    ENSEMBL proteins: 
     ENSP00000298310   ENSP00000452540   ENSP00000451740   ENSP00000452174   ENSP00000438309  
     ENSP00000441016   ENSP00000371570  

    NEMF Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for NEMF
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    Novus Biologicals NEMF Protein
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    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

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    Search for Antibodies for NEMF at Abcam
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    LSBio Antibodies in human, mouse, rat for NEMF

    NEMF Assay Products:

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    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR008616 Fibro-bd_N
     IPR008532 DUF814
     IPR021846 DUF3441

    Graphical View of Domain Structure for InterPro Entry O60524

    ProtoNet protein and cluster: O60524

    1 Blocks protein domain: IPB008532 Protein of unknown function DUF814

    UniProtKB/Swiss-Prot: NEMF_HUMAN, O60524
    Domain: The N-terminal domain contains a nuclear export signal. The C-terminal domain may interact with cargo
    proteins (By similarity)
    Similarity: Belongs to the NEMF family


    NEMF for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NEMF_HUMAN, O60524
    Function: Plays a role in nuclear export

    Phenotypes:
         1 MGI phenotypic allele for Nemf (no phenotypes)


    NEMF for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NEMF
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for NEMF

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NEMF
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NEMF

    miRNA
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    miRTarBase miRNAs that target NEMF:
    hsa-mir-16-5p (MIRT031899)

    Block miRNA regulation of human, mouse, rat NEMF using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NEMF (see all 12):
    hsa-miR-203 hsa-miR-3163 hsa-miR-3671 hsa-miR-579 hsa-miR-548e hsa-miR-452* hsa-miR-410 hsa-miR-942
    SwitchGear 3'UTR luciferase reporter plasmidNEMF 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Predesigned siRNA for gene silencing in human, mouse, rat NEMF

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    GenScript: all cDNA clones in your preferred vector: NEMF (NM_004713)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NEMF
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NEMF

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    Browse ESI BIO Cell Lines and PureStem Progenitors for NEMF 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NEMF


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NEMF_HUMAN, O60524: Nucleus (Potential)

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm ----

    NEMF for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NEMF
    Interactions:

        Search GeneGlobe Interaction Network for NEMF

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for NEMF (O605243 ENSP000002983104) via UniProtKB, MINT, STRING, and/or I2D (see all 95)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000096150P622693I2D: score=1 
    ENSG00000223367P622693I2D: score=1 
    ENSG00000226225P622693I2D: score=1 
    ENSG00000235650P622693I2D: score=1 
    RPS18P622693I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0044780bacterial-type flagellum assembly ----
    GO:0051168nuclear export IMP16103875

    NEMF for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NEMF



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for NEMF gene: 
    NM_004713.3  

    Unigene Cluster for NEMF:

    Nuclear export mediator factor
    Hs.655964  [show with all ESTs]
    Unigene Representative Sequence: NM_004713
    18 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000298310(uc010anj.1 uc001wxc.3 uc010tqi.2) ENST00000556691
    ENST00000556074(uc001wwz.3 uc001wxa.3) ENST00000556925 ENST00000557193
    ENST00000554275 ENST00000555970(uc001wxd.1) ENST00000555863 ENST00000555411
    ENST00000557380(uc010anq.1) ENST00000553696 ENST00000556882 ENST00000554626
    ENST00000556672 ENST00000554162 ENST00000545773(uc001wxe.2) ENST00000546046
    ENST00000382135
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat NEMF using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NEMF (see all 12):
    hsa-miR-203 hsa-miR-3163 hsa-miR-3671 hsa-miR-579 hsa-miR-548e hsa-miR-452* hsa-miR-410 hsa-miR-942
    SwitchGear 3'UTR luciferase reporter plasmidNEMF 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for NEMF
    Predesigned siRNA for gene silencing in human, mouse, rat NEMF
    Clone
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    OriGene ORF clones in mouse, rat for NEMF
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NEMF (NM_004713)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NEMF
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NEMF
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for NEMF
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NEMF
      QuantiTect SYBR Green Assays in human, mouse, rat NEMF
      QuantiFast Probe-based Assays in human, mouse, rat NEMF

    Additional mRNA sequence: 

    AF039687.1 AK000913.1 AK093783.1 AK293236.1 AK295010.1 AK304695.1 AK308537.1 AK314281.1 
    BC006001.1 BC020794.2 BC056687.1 BC064364.1 BC107764.1 BX640804.1 BX640807.1 BX648598.1 
    BX648753.1 

    Selected DOTS entries (see all 27):

    DT.314388  DT.207458  DT.100679213  DT.97845610  DT.100737565  DT.101984317  DT.70103737  DT.95338023 
    DT.100737564  DT.95266837  DT.40130729  DT.95257653  DT.95269900  DT.100754441  DT.120747983  DT.120748053 
    DT.120748055  DT.40113659  DT.422407  DT.86850342  DT.100652426  DT.40118666  DT.40228562  DT.91817523 

    Selected AceView cDNA sequences (see all 208):

    CA392683 AA626602 NM_004713 BG287032 BC031007 CR622792 AI480251 AJ457797 
    BC064364 AA669916 AA159181 BQ632296 CR597660 AK093783 BM806262 AW237403 
    BM469479 BM455267 BM785476 AA553574 BC020794 BM458431 CB135004 AK000913 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for NEMF (see all 9)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14a · 14b ^ 15 ^ 16 ^ 17a · 17b ^ 18 ^ 19 ^ 20 ^ 21 ^
    SP1:                                -                                                                                                                           
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 22 ^ 23 ^ 24a · 24b ^ 25 ^ 26 ^ 27a · 27b
    SP1:                                                
    SP2:                                                
    SP3:                                                
    SP4:                                                
    SP5:              -                                 


    ECgene alternative splicing isoforms for NEMF

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NEMF expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    NEMF Expression
    About this image

    NEMF Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NEMF Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.655964

    UniProtKB/Swiss-Prot: NEMF_HUMAN, O60524
    Tissue specificity: Expressed in brain, heart, liver, lung, spleen, and skeletal muscle. Also expressed at lower
    levels in stomach and testis

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    QuantiFast Probe-based Assays in human, mouse, rat NEMF
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NEMF

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NEMF gene from Selected species (see all 23)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nemf1 , 5 nuclear export mediator factor1, 5 88.57(n)1
    90.13(a)1
      12 (28.78 cM)5
    662441  NM_025441.31  NP_079717.21 
     693115445 
    chicken
    (Gallus gallus)
    Aves NEMF1 nuclear export mediator factor 73.92(n)
    78.05(a)
      428926  NM_001252329.1  NP_001239258.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    (see all 3)
    Uncharacterized protein
    (see all 3)
    85(a)
    84(a)
    (see all 3)
    many → 1
    many → 1
    (see all 3)
    GL343627.1(342325-354270)
    GL343627.1(332775-338137)
    African clawed frog
    (Xenopus laevis)
    Amphibia BC045243.12   -- 75.63(n)    BC045243.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.103622 Transcribed sequence with moderate similarity to protein more 74.2(n)    57091435 
    fruit fly
    (Drosophila melanogaster)
    Insecta Clbn1 Caliban 57.82(n)
    57.3(a)
      43018  NM_001170250.1  NP_001163721.1 
    worm
    (Caenorhabditis elegans)
    Secernentea Y82E9BR.181 Y82E9BR.18 52.92(n)
    46.63(a)
      175303  NM_065010.5  NP_497411.2 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes TAE2(YPL009C)4 Protein of unknown function, involved in protein translation; more   --   16(538936-535820) 856098  NP_015316.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons emb14411 emb1441 51.37(n)
    41.82(a)
      835056  NM_124371.3  NP_199804.1 
    rice
    (Oryza sativa)
    Liliopsida Os.268142 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 73.79(n)    AK101383.1 


    ENSEMBL Gene Tree for NEMF (if available)
    TreeFam Gene Tree for NEMF (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NEMF (see all 1602)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1419339841,2
    --31233592(+) GTGCTA/GTATTG 1 -- ds50010--------
    rs559217501,2
    C--31233939(+) TTTCTC/TTACAT 1 -- ut310--------
    rs145051,2
    C,F,H--31233973(+) ACCTCT/CCAAAT 1 -- ut31 ese37Minor allele frequency- C:0.00MN NA WA 198
    rs1428568821,2
    --31233983(+) TTTCAA/GGAAAA 1 -- ut310--------
    rs1506423241,2
    --31233989(+) GAAAAG/TGTAGA 1 -- ut310--------
    rs562947621,2
    C--31234136(+) TAGTTC/TATTTG 1 -- ut310--------
    rs1398424251,2
    --31234462(+) ACATGC/GTGCTT 1 -- ut310--------
    rs1837652501,2
    --31234696(+) TTCCAA/GACTTT 1 -- int10--------
    rs1457955021,2
    C--31234790(+) TCAGT-/CCTCCA 1 -- int10--------
    rs732836601,2
    C,F--31234850(+) TTTTCT/CCTTGC 2 /R syn13Minor allele frequency- C:0.01WA NA EU 5791

    HapMap Linkage Disequilibrium report for NEMF (50249997 - 50319921 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for NEMF:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv509533CNV Insertion20534489
    esv28926CNV Gain+Loss19812545

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608378    OMIM disorders: --

    2 diseases for NEMF:    
    About MalaCards
    lung cancer    malaria


    NEMF for disorders           About GeneDecksing


    Export disorders for NEMF gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NEMF gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with NEMF)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of human colon cancer antigens recognized by autologous antibodies. (PubMed id 9610721)1, 2, 3 Scanlan M.J.... Old L.J. (Int. J. Cancer 1998)
    2. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    3. Drosophila caliban, a nuclear export mediator, can function as a tumor suppressor in human lung cancer cells. (PubMed id 16103875)1, 2 Bi X....Mortin M.A. (Oncogene 2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. Assignment of the serologically defined colon cancer antigen 1 gene (SDCCAG1) to human chromosome band 14q22 by in situ hybridization. (PubMed id 10575219)1, 3 Carbonnelle D....Roussakis C. (Cytogenet. Cell Genet. 1999)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    8. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    10. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9147 HGNC: 10663 AceView: SDCCAG1 Ensembl:ENSG00000165525 euGenes: HUgn9147
    ECgene: NEMF H-InvDB: NEMF

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for NEMF Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for NEMF gene:
    Search GeneIP for patents involving NEMF

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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