Aliases for NELL1 Gene
External Ids for NELL1 Gene
Previous GeneCards Identifiers for NELL1 Gene
This gene encodes a cytoplasmic protein that contains epidermal growth factor (EGF)-like repeats. The encoded heterotrimeric protein may be involved in cell growth regulation and differentiation. A similar protein in rodents is involved in craniosynostosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
GeneCards Summary for NELL1 Gene
NELL1 (Neural EGFL Like 1) is a Protein Coding gene. Diseases associated with NELL1 include gnathodiaphyseal dysplasia and osteoblastoma. Among its related pathways are Signaling by GPCR and Developmental Biology. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is NPNT.
UniProtKB/Swiss-Prot for NELL1 Gene
Plays a role in the control of cell growth and differentiation. Promotes osteoblast cell differentiation and terminal mineralization.