Aliases for NELL1 Gene
External Ids for NELL1 Gene
Previous GeneCards Identifiers for NELL1 Gene
This gene encodes a cytoplasmic protein that contains epidermal growth factor (EGF)-like repeats. The encoded heterotrimeric protein may be involved in cell growth regulation and differentiation. A similar protein in rodents is involved in craniosynostosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
GeneCards Summary for NELL1 Gene
NELL1 (Neural EGFL Like 1) is a Protein Coding gene. Diseases associated with NELL1 include craniosynostosis and chondroblastic osteosarcoma. Among its related pathways are Signaling by GPCR and Interleukin-3, 5 and GM-CSF signaling. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is NELL2.
UniProtKB/Swiss-Prot for NELL1 Gene
Plays a role in the control of cell growth and differentiation. Promotes osteoblast cell differentiation and terminal mineralization.