Aliases for NEK9 Gene
External Ids for NEK9 Gene
GeneCards Summary for NEK9 Gene
NEK9 (NIMA-Related Kinase 9) is a Protein Coding gene. Among its related pathways are Cell Cycle, Mitotic and Cell Cycle, Mitotic. GO annotations related to this gene include protein serine/threonine kinase activity and protein kinase binding. An important paralog of this gene is NEK2.
UniProtKB/Swiss-Prot for NEK9 Gene
Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression. Phosphorylates NEK6 and NEK7 and stimulates their activity by releasing the autoinhibitory functions of Tyr-108 and Tyr-97 respectively.