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Aliases for NEK9 Gene

Aliases for NEK9 Gene

  • NIMA Related Kinase 9 2 3 5
  • NIMA (Never In Mitosis Gene A)- Related Kinase 9 2 3
  • NimA-Related Protein Kinase 9 3 4
  • Nercc1 Kinase 3 4
  • EC 2.7.11.1 4 58
  • NERCC 3 4
  • Serine/Threonine-Protein Kinase Nek9 3
  • Never In Mitosis A-Related Kinase 9 4
  • NimA-Related Kinase 8 4
  • KIAA1995 4
  • LCCS10 3
  • NERCC1 3
  • APUG 3
  • NEK8 4
  • NC 3

External Ids for NEK9 Gene

Previous GeneCards Identifiers for NEK9 Gene

  • GC14M073077
  • GC14M069365
  • GC14M073538
  • GC14M073541
  • GC14M074618
  • GC14M075548
  • GC14M055716

Summaries for NEK9 Gene

Entrez Gene Summary for NEK9 Gene

  • This gene encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. The encoded protein is activated in mitosis and, in turn, activates other family members during mitosis. This protein also mediates cellular processes that are essential for interphase progression. [provided by RefSeq, Jul 2016]

GeneCards Summary for NEK9 Gene

NEK9 (NIMA Related Kinase 9) is a Protein Coding gene. Diseases associated with NEK9 include Nevus Comedonicus, Somatic and Arthrogryposis, Perthes Disease, And Upward Gaze Palsy. Among its related pathways are Cell Cycle, Mitotic and Transport of the SLBP independent Mature mRNA. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is NEK8.

UniProtKB/Swiss-Prot for NEK9 Gene

  • Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression. Phosphorylates NEK6 and NEK7 and stimulates their activity by releasing the autoinhibitory functions of Tyr-108 and Tyr-97 respectively.

Gene Wiki entry for NEK9 Gene

Additional gene information for NEK9 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NEK9 Gene

Genomics for NEK9 Gene

Regulatory Elements for NEK9 Gene

Enhancers for NEK9 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14H074564 1.9 FANTOM5 Ensembl ENCODE dbSUPER 23.6 +556.8 556794 11 PKNOX1 SIN3A FEZF1 GLI4 ZBTB7B ZNF416 FOS KLF7 SP3 YY2 ELMSAN1 ZNF410 YLPM1 FCF1 ENSG00000258559 MLH3 NEK9 PROX2 LTBP2 ENSG00000259005
GH14H074880 1.4 Ensembl ENCODE 21.6 +243.2 243181 6 PKNOX1 MLX ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 ZNF143 ZNF207 DLST RPS6KL1 ZNF410 NEK9 YLPM1 PGF TTLL5 ENSG00000258559 FCF1 MLH3
GH14H075249 2.5 VISTA FANTOM5 Ensembl ENCODE dbSUPER 11.7 -127.7 -127698 12 HDGF PKNOX1 FOXA2 MLX ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZBTB7B NEK9 IFT43 FOS ABCD4 ENSG00000258740 YLPM1 LOC105370571 RNU4ATAC14P
GH14H075273 1.8 FANTOM5 ENCODE dbSUPER 11 -150.5 -150477 9 HDGF PKNOX1 ARID4B SIN3A ZNF2 ZBTB7B YY1 SLC30A9 ZNF143 ZNF207 FOS GPATCH2L FCF1 NEK9 ACYP1 ENSG00000258559 ENSG00000258740 JDP2 FLVCR2 BATF
GH14H075293 1.7 FANTOM5 ENCODE dbSUPER 11.2 -169.1 -169094 6 HDGF PKNOX1 ARID4B SIN3A FEZF1 YBX1 ZNF2 YY1 ZNF766 ZNF143 JDP2 TMED10 NEK9 LINC01220 BATF FOS DPPA5P4 SYNDIG1L FLVCR2
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around NEK9 on UCSC Golden Path with GeneCards custom track

Promoters for NEK9 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000070853 244 1801 HDGF PKNOX1 FOXA2 MLX ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143

Genomic Location for NEK9 Gene

Chromosome:
14
Start:
75,079,353 bp from pter
End:
75,127,344 bp from pter
Size:
47,992 bases
Orientation:
Minus strand

Genomic View for NEK9 Gene

Genes around NEK9 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NEK9 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NEK9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NEK9 Gene

Proteins for NEK9 Gene

  • Protein details for NEK9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TD19-NEK9_HUMAN
    Recommended name:
    Serine/threonine-protein kinase Nek9
    Protein Accession:
    Q8TD19
    Secondary Accessions:
    • Q52LK6
    • Q8NCN0
    • Q8TCY4
    • Q9UPI4
    • Q9Y6S4
    • Q9Y6S5
    • Q9Y6S6

    Protein attributes for NEK9 Gene

    Size:
    979 amino acids
    Molecular mass:
    107168 Da
    Cofactor:
    Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
    Quaternary structure:
    • Homodimer. Binds to Ran GTPase. Has a greater affinity for Ran-GDP over Ran-GTP. Interacts with NEK6, NEK7 and BICD2. Interacts with SSRP1 and SUPT16H, the 2 subunits of the FACT complex. Interacts with DYNLL1; phosphorylation at Ser-944 strongly reduces DYNLL1 binding.
    SequenceCaution:
    • Sequence=AAD31936.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=BAC02704.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for NEK9 Gene

neXtProt entry for NEK9 Gene

Selected DME Specific Peptides for NEK9 Gene

Q8TD19:
  • DKILRQK
  • GTPYYMSPE

Post-translational modifications for NEK9 Gene

  • Autophosphorylated on serine and threonine residues (PubMed:27153399). When complexed with FACT, exhibits markedly elevated phosphorylation on Thr-210. During mitosis, not phosphorylated on Thr-210. Phosphorylated by CDK1 in vitro.
  • Ubiquitination at Lys327, posLast=606606, and Lys650
  • Modification sites at PhosphoSitePlus

Domains & Families for NEK9 Gene

Gene Families for NEK9 Gene

IUPHAR :
Human Protein Atlas (HPA):
  • Enzymes
  • Plasma proteins
  • Predicted intracellular proteins
  • Transporters

Graphical View of Domain Structure for InterPro Entry

Q8TD19

UniProtKB/Swiss-Prot:

NEK9_HUMAN :
  • Dimerizes through its coiled-coil domain.
  • Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
Domain:
  • Dimerizes through its coiled-coil domain.
Family:
  • Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
genes like me logo Genes that share domains with NEK9: view

Function for NEK9 Gene

Molecular function for NEK9 Gene

UniProtKB/Swiss-Prot CatalyticActivity:
ATP + a protein = ADP + a phosphoprotein.
UniProtKB/Swiss-Prot EnzymeRegulation:
Activated during mitosis by intramolecular autophosphorylation. Activity and autophosphorylation is activated by manganese >> magnesium ions. Sensitive to increasing concentration of detergents. It is not cell-cycle regulated but activity is higher in G0-arrested cells.
UniProtKB/Swiss-Prot Function:
Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression. Phosphorylates NEK6 and NEK7 and stimulates their activity by releasing the autoinhibitory functions of Tyr-108 and Tyr-97 respectively.

Enzyme Numbers (IUBMB) for NEK9 Gene

Phenotypes From GWAS Catalog for NEK9 Gene

Gene Ontology (GO) - Molecular Function for NEK9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004672 protein kinase activity IEA --
GO:0004674 protein serine/threonine kinase activity IEA --
GO:0005515 protein binding IPI 17353931
GO:0005524 ATP binding IEA --
GO:0016301 kinase activity IEA --
genes like me logo Genes that share ontologies with NEK9: view
genes like me logo Genes that share phenotypes with NEK9: view

Human Phenotype Ontology for NEK9 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for NEK9 Gene

MGI Knock Outs for NEK9:
  • Nek9 tm1a(EUCOMM)Wtsi

Animal Model Products

  • Taconic Biosciences Mouse Models for NEK9

CRISPR Products

miRNA for NEK9 Gene

miRTarBase miRNAs that target NEK9

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for NEK9
  • Applied Biological Materials Clones for NEK9
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Transcription Factor Targets and HOMER Transcription for NEK9 Gene

Localization for NEK9 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NEK9 Gene

Cytoplasm. Nucleus.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for NEK9 gene
Compartment Confidence
cytosol 5
nucleus 4
mitochondrion 3
cytoskeleton 2
plasma membrane 1
extracellular 1
peroxisome 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for NEK9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
GO:0005813 colocalizes_with centrosome IDA 20873783
GO:0005829 cytosol TAS --
genes like me logo Genes that share ontologies with NEK9: view

Pathways & Interactions for NEK9 Gene

genes like me logo Genes that share pathways with NEK9: view

Pathways by source for NEK9 Gene

SIGNOR curated interactions for NEK9 Gene

Activates:
Is activated by:

Gene Ontology (GO) - Biological Process for NEK9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006468 protein phosphorylation IEA --
GO:0007049 cell cycle IEA --
GO:0007077 mitotic nuclear envelope disassembly TAS --
GO:0016310 phosphorylation IEA --
GO:0051301 cell division IEA --
genes like me logo Genes that share ontologies with NEK9: view

Drugs & Compounds for NEK9 Gene

(4) Drugs for NEK9 Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Manganese Approved Nutra 35
Guanosine triphosphate Experimental Pharma 0
ATP Nutra Agonist 0
Magnesium Nutra 0

(1) Additional Compounds for NEK9 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
ADP
  • Adenosindiphosphorsaeure
  • Adenosine 5'-pyrophosphate
  • Adenosine diphosphate
  • Adenosine pyrophosphate
  • Adenosine-5'-diphosphate
Full agonist, Agonist 58-64-0
genes like me logo Genes that share compounds with NEK9: view

Transcripts for NEK9 Gene

mRNA/cDNA for NEK9 Gene

Unigene Clusters for NEK9 Gene

NIMA-related kinase 9:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for NEK9
  • Applied Biological Materials Clones for NEK9
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for NEK9 Gene

ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17a · 17b ^
SP1: - -
SP2: - -
SP3: - -
SP4:
SP5:
SP6: - - - -
SP7:
SP8:
SP9:
SP10:

ExUns: 18a · 18b ^ 19 ^ 20a · 20b · 20c ^ 21 ^ 22 ^ 23 ^ 24a · 24b
SP1: - - -
SP2:
SP3:
SP4: -
SP5:
SP6:
SP7: - - -
SP8:
SP9:
SP10:

Relevant External Links for NEK9 Gene

GeneLoc Exon Structure for
NEK9
ECgene alternative splicing isoforms for
NEK9

Expression for NEK9 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for NEK9 Gene

Protein differential expression in normal tissues from HIPED for NEK9 Gene

This gene is overexpressed in Lymph node (15.4) and Peripheral blood mononuclear cells (11.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for NEK9 Gene



Protein tissue co-expression partners for NEK9 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of NEK9 Gene:

NEK9

SOURCE GeneReport for Unigene cluster for NEK9 Gene:

Hs.7200

mRNA Expression by UniProt/SwissProt for NEK9 Gene:

Q8TD19-NEK9_HUMAN
Tissue specificity: Most abundant in heart, liver, kidney and testis. Also expressed in smooth muscle cells and fibroblasts.

Evidence on tissue expression from TISSUES for NEK9 Gene

  • Nervous system(4.6)
  • Liver(4.3)
  • Lymph node(4.3)
  • Spleen(4.3)
  • Blood(4.2)
  • Kidney(2.3)
  • Lung(2.2)
genes like me logo Genes that share expression patterns with NEK9: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for NEK9 Gene

Orthologs for NEK9 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for NEK9 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia NEK9 33 34
  • 99.47 (n)
dog
(Canis familiaris)
Mammalia NEK9 34 33
  • 93.99 (n)
OneToOne
cow
(Bos Taurus)
Mammalia NEK9 34 33
  • 92.73 (n)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia NEK9 34
  • 91 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Nek9 33
  • 90.39 (n)
mouse
(Mus musculus)
Mammalia Nek9 33 16 34
  • 90.31 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia NEK9 34
  • 78 (a)
OneToOne
chicken
(Gallus gallus)
Aves NEK9 33 34
  • 79.28 (n)
lizard
(Anolis carolinensis)
Reptilia NEK9 34
  • 81 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia nek9 33
  • 70.15 (n)
Str.2930 33
African clawed frog
(Xenopus laevis)
Amphibia LOC398600 33
zebrafish
(Danio rerio)
Actinopterygii LOC100334361 33
  • 59.37 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG10951 35
  • 30 (a)
worm
(Caenorhabditis elegans)
Secernentea Y39G10AR.4 35
  • 35 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes KIN3 34
  • 25 (a)
OneToMany
Species where no ortholog for NEK9 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for NEK9 Gene

ENSEMBL:
Gene Tree for NEK9 (if available)
TreeFam:
Gene Tree for NEK9 (if available)

Paralogs for NEK9 Gene

Paralogs for NEK9 Gene

genes like me logo Genes that share paralogs with NEK9: view

Variants for NEK9 Gene

Sequence variations from dbSNP and Humsavar for NEK9 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs142859694 Pathogenic, Arthrogryposis, Perthes disease, and upward gaze palsy (APUG) [MIM:614262] 75,097,231(+) CCAGG(C/T)GGCCA reference, missense
rs879253775 Pathogenic, Nevus comedonicus (NC) [MIM:617025] 75,120,534(-) CTGCA(C/T)CCATA reference, missense
VAR_040927 A lung neuroendocrine carcinoma sample
VAR_077802 Nevus comedonicus (NC) [MIM:617025]
rs757011098 Pathogenic 75,106,541(+) GTTTC(A/G/T)TGTCA reference, synonymous-codon, stop-gained

Structural Variations from Database of Genomic Variants (DGV) for NEK9 Gene

Variant ID Type Subtype PubMed ID
nsv832833 CNV gain 17160897

Variation tolerance for NEK9 Gene

Residual Variation Intolerance Score: 18.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.36; 63.37% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for NEK9 Gene

Human Gene Mutation Database (HGMD)
NEK9
SNPedia medical, phenotypic, and genealogical associations of SNPs for
NEK9

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NEK9 Gene

Disorders for NEK9 Gene

MalaCards: The human disease database

(4) MalaCards diseases for NEK9 Gene - From: HGMD, OMIM, ClinVar, Orphanet, Swiss-Prot, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
nevus comedonicus, somatic
  • nevus comedonicus
arthrogryposis, perthes disease, and upward gaze palsy
  • apug
lethal congenital contracture syndrome 10
  • nek9-related lethal skeletal dysplasia
senior-loken syndrome-1
  • senior-loken syndrome
- elite association - COSMIC cancer census association via MalaCards
Search NEK9 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

NEK9_HUMAN
  • Arthrogryposis, Perthes disease, and upward gaze palsy (APUG) [MIM:614262]: An autosomal recessive, syndromic form of arthrogryposis, a disease characterized by persistent joints flexure or contracture. APUG patients manifest an unusual combination of arthrogryposis, upward gaze palsy, and avascular necrosis of the hip (Perthes disease). {ECO:0000269 PubMed:26633546}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Lethal congenital contracture syndrome 10 (LCCS10) [MIM:617022]: A form of lethal congenital contracture syndrome, an autosomal recessive disorder characterized by degeneration of anterior horn neurons, extreme skeletal muscle atrophy and congenital non-progressive joint contractures. The contractures can involve the upper or lower limbs and/or the vertebral column, leading to various degrees of flexion or extension limitations evident at birth. {ECO:0000269 PubMed:26908619}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Nevus comedonicus (NC) [MIM:617025]: A rare type of epidermal nevus characterized by closely arranged, dilated, plugged follicular ostia in a honeycomb pattern. The plugged ostia contain lamellated keratinaceous material, and their appearance resembles black dots. NC may be non-pyogenic with an acne-like appearance or associated with the formation of cysts, papules, pustules, and abscesses. Most commonly it affects the face and neck area and, by exception, other anatomical regions, including genital area, palms, and soles. NC lesions might present with various patterns of distribution: unilateral, bilateral, linear, interrupted, segmental, or blaschkoid. {ECO:0000269 PubMed:27153399}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Relevant External Links for NEK9

Genetic Association Database (GAD)
NEK9
Human Genome Epidemiology (HuGE) Navigator
NEK9
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
NEK9
genes like me logo Genes that share disorders with NEK9: view

No data available for Genatlas for NEK9 Gene

Publications for NEK9 Gene

  1. Purification, cloning, and characterization of Nek8, a novel NIMA-related kinase, and its candidate substrate Bicd2. (PMID: 11864968) Holland PM … Virca GD (The Journal of biological chemistry 2002) 2 3 4 22 60
  2. An autoinhibitory tyrosine motif in the cell-cycle-regulated Nek7 kinase is released through binding of Nek9. (PMID: 19941817) Richards MW … Bayliss R (Molecular cell 2009) 3 4 22 60
  3. Recessive NEK9 mutation causes a lethal skeletal dysplasia with evidence of cell cycle and ciliary defects. (PMID: 26908619) Casey JP … Lynch SA (Human molecular genetics 2016) 3 4 60
  4. Somatic Mutations in NEK9 Cause Nevus Comedonicus. (PMID: 27153399) Levinsohn JL … Choate KA (American journal of human genetics 2016) 3 4 60
  5. Structural analysis of the regulation of the DYNLL/LC8 binding to Nek9 by phosphorylation. (PMID: 23482567) Gallego P … Reverter D (The Journal of biological chemistry 2013) 3 4 60

Products for NEK9 Gene

  • Addgene plasmids for NEK9

Sources for NEK9 Gene

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