NEK9 Gene
protein-coding GIFtS: 60
GCID: GC14M075548
|
|
NIMA-related kinase 9(Previous name: NIMA (never in mitosis gene a)- related kinase 9 )
| |
Aliases for NEK9 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| NIMA-Related Kinase 91 2 | | EC 2.7.11.13 8 | | NERCC1 2 3 | | NERCC12 5 | | Nek81 2 3 | | DKFZp434D09351 | | NIMA (Never In Mitosis Gene A)- Related Kinase 91 2 | | MGC167141 | | Nercc1 Kinase2 3 | | NIMA-Related Kinase Nek82 | | Never In Mitosis A-Related Kinase 92 3 | | Serine/Threonine-Protein Kinase Nek92 | | NimA-Related Kinase 82 3 | | KIAA19953 | | NimA-Related Protein Kinase 92 3 | | NEK83 |
Export aliases for NEK9 gene to outside databasesPrevious GC identifers: GC14M073077 GC14M069365 GC14M073538 GC14M073541 GC14M074618 GC14M055716 |
Summaries for NEK9 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: NEK9_HUMAN, Q8TD19Function: Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosomeseparation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phaseprogression. Phosphorylates NEK6 and NEK7 and stimulates their activity by releasing the autoinhibitory functions ofTyr-108 and Tyr-97 respectively Gene Wiki entry for NEK9
|
Genomic Views for NEK9 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000014.8 NC_018925.1 NT_026437.12
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the NEK9 gene promoter: STAT1 AML1a STAT1beta STAT5A CUTL1 Nkx2-5 STAT1alpha c-Ets-1 YY1 Sox9 Other transcription factors
Search SABiosciences Chromatin IP Primers for NEK9
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NEK9 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 14q24.3 Ensembl cytogenetic band: 14q24.3 HGNC cytogenetic band: 14q24.2NEK9 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 14 GeneLoc Exon Structure GeneLoc location for GC14M075548: view genomic region
(about GC identifiers)
Start:
|
75,548,818 bp from pter |
End:
|
75,594,047 bp from pter |
Size:
|
45,230 bases |
Orientation:
|
minus strand |
|
Proteins for NEK9 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: NEK9_HUMAN, Q8TD19 (See
protein sequence)Recommended Name: Serine/threonine-protein kinase Nek9 Size: 979 amino acids; 107168 Da
Cofactor: Magnesium
Subunit: Homodimer. Binds to Ran GTPase. Has a greater affinity for Ran-GDP over Ran-GTP. Interacts with NEK6, NEK7 andBICD2. Interacts with SSRP1 and SUPT16H, the 2 subunits of the FACT complex
Subcellular location: Cytoplasm. Nucleus
Developmental stage: Expression varied mildly across the cell cycle, with highest expression observed in G1 andstationary-phase cells
Sequence caution: Sequence=AAD31936.1; Type=Erroneous gene model prediction; Sequence=BAC02704.1; Type=Erroneousinitiation; Note=Translation N-terminally shortened;
Secondary accessions: Q52LK6 Q8NCN0 Q8TCY4 Q9UPI4 Q9Y6S4 Q9Y6S5 Q9Y6S6Explore the universe of human proteins at neXtProt for NEK9: NX_Q8TD19
Post-translational modifications:
Autophosphorylated on serine and threonine residues. When complexed with FACT, exhibits markedly elevatedphosphorylation on Thr-210. During mitosis, not phosphorylated on Thr-210. Phosphorylated by CDK1 in vitro1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8TD19 2 DME Specific Peptides for NEK9 (Q8TD19)
NEK9 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_149107.4 ENSEMBL proteins: ENSP00000238616 ENSP00000451604 ENSP00000450943 ENSP00000452537 ENSP00000452544 Reactome Protein details: Q8TD19 Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
NEK9 for ontologies About GeneDecksing
NEK9 Antibody Products: Assay Products for NEK9: |
Protein
Domains / Families for NEK9 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NEK9 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry Q8TD19ProtoNet protein and cluster: Q8TD19 UniProtKB/Swiss-Prot: NEK9_HUMAN, Q8TD19Domain: Dimerizes through its coiled-coil domainSimilarity: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamilySimilarity: Contains 1 protein kinase domainSimilarity: Contains 6 RCC1 repeats |
Function for NEK9 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: NEK9_HUMAN, Q8TD19Function: Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosomeseparation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phaseprogression. Phosphorylates NEK6 and NEK7 and stimulates their activity by releasing the autoinhibitory functions ofTyr-108 and Tyr-97 respectivelyCatalytic activity: ATP + a protein = ADP + a phosphoproteinEnzyme regulation: Activated during mitosis by intramolecular autophosphorylation. Activity and autophosphorylation isactivated by manganese >> magnesium ions. Sensitive to increasing concentration of detergents. It is not cell-cycleregulated but activity is higher in G0-arrested cellsEnzyme Number (IUBMB): EC 2.7.11.11 2
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NEK9 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NEK9 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: NEK9 (NM_033116) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NEK9 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NEK9  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NEK9 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
NEK9 for ontologies About GeneDecksing
6 GenomeRNAi human phenotypes for NEK9:
|
Pathways & Interactions for NEK9 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Clearance of Nuclear Envelope Membranes from Chromatin | | | 2 | M Phase | | | 3 | Cell Cycle | |
Pathway sources See GeneCards unified pathways Show all pathways
5/7
Reactome Pathways for NEK9 (see all 7)
NEK9 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NEK9
STRING Interaction
Network Preview (showing 5 interactants - click image to see 16)
 5/257 Interacting proteins for NEK9 (Q8TD191, 2, 3 ENSP000002386164) via UniProtKB, MINT, STRING, and/or I2D (see all 257)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| SSRP1 | Q089452, 3, ENSP000002784124 | MINT-2984265 I2D:
score=4 STRING: ENSP00000278412 | | GABARAPL2 | P605201, 3, ENSP000000372434 | EBI-1044009,EBI-2973440 I2D:
score=3 STRING: ENSP00000037243 | | GABARAPL1 | Q9H0R81, 3 | EBI-1044009,EBI-3240381 I2D:
score=3 | | GABARAP | O951661, 3 | EBI-1044009,EBI-712001 I2D:
score=1 | | HSP90AB1 | P082381, 3 | EBI-1044009,EBI-352572 I2D:
score=1 | About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
NEK9 for ontologies About GeneDecksing
|
Drugs & Compounds for NEK9 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for NEK9
5 HMDB Compounds for NEK9 About this table Search CenterWatch for drugs/clinical trials and news about NEK9 
|
Transcripts for NEK9 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for NEK9 gene: NM_033116.4 Unigene Cluster for NEK9: NIMA-related kinase 9 Hs.7200 [show with all ESTs]Unigene Representative Sequence: NM_03311611 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000238616(uc001xrl.3) ENST00000555405(uc001xrj.3) ENST00000557026(uc001xrk.3) ENST00000555763 ENST00000556170 ENST00000555537 ENST00000554258 ENST00000557673 ENST00000555961 ENST00000553823 ENST00000553945
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NEK9 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NEK9 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: NEK9 (NM_033116) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NEK9 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NEK9  |
Additional cDNA sequence: AB082526.1 AK128693.1 AL117502.1 AL832633.2 AL833036.1 AY048580.1 AY080896.1 BC001714.1 BC009336.2 BC062742.1 BC093881.1 BC112101.1 L40402.1 17 DOTS entries: DT.100795741 DT.97800508 DT.40107140 DT.219045 DT.120791357 DT.91756610 DT.91638460 DT.100029539 DT.100795744 DT.100795742 DT.102822232 DT.120791516 DT.40126940 DT.95177241 DT.95310804 DT.99959625 DT.120791347 11 AceView cDNA sequences: AI884951 BE327500 AI859026 AI950160 AI199074 AA827006 AI972045 AW339836 AA625810 AW195739 AA528182 GeneLoc Exon Structure
5/10 Alternative Splicing Database (ASD) splice patterns (SP) for NEK9 (see all 10) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13a | · | 13b | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17a | · | 17b | ^ | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | - |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | - |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 18a | · | 18b | ^ | 19 | ^ | 20a | · | 20b | · | 20c | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24a | · | 24b | |
| SP1: | |   | - |   | |   | - |   | |   | |   | |   | |   | - |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for NEK9
|
Expression for NEK9 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NEK9 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: GAGCTGATGG
About this image See NEK9 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for NEK9
SOURCE GeneReport for Unigene cluster: Hs.7200 UniProtKB/Swiss-Prot: NEK9_HUMAN, Q8TD19Tissue specificity: Most abundant in heart, liver, kidney and testis. Also expressed in smooth muscle cells andfibroblasts SABiosciences Custom PCR Arrays for NEK9
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NEK9 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NEK9 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NEK9 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NEK9 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NEK9 |
Orthologs for NEK9 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for NEK9 gene from 4/22 species (see all 22) About this table
ENSEMBL Gene Tree for NEK9 (if available) TreeFam Gene Tree for NEK9 (if available)  |
Paralogs for NEK9 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for NEK9 gene
- NEK42 NEK62 NEK12 NEK112 NEK32 NEK72 NEK52 NEK22
- NEK82 NEK102
18/95 SIMAP similar genes for NEK9 using alignment to 7 protein entries: NEK9_HUMAN (see all proteins)
(see all similar genes):NEK5 NEK3 MAP2K1 MST094 CDK11B MAPK4 DKFZp564L2416 STK25 MOK NLK NEK8 MAP3K4 MAPK3 MAPK7 MINK1 ULK1 MELK NEK6
NEK9 for paralogs About GeneDecksing
|
Genomic Variants for NEK9 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 14 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for NEK9 (75548818 - 75594047 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for NEK9: --  | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases for NEK9 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NEK9 for disorders About GeneDecksing
OMIM gene information: 609798
OMIM disorders: --
7 diseases for NEK9: About MalaCardssenior-loken syndrome polycystic kidney disease cystic kidney cramps kidney disease breast cancer malaria 3 diseases from the University of Copenhagen DISEASES database for NEK9:Nephronophthisis Polycystic kidney disease Cystic kidney Human Genome Epidemiology (HuGE) Navigator: NEK9 (2 documents) Export disorders for NEK9 gene to outside databases
|
Publications for NEK9 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NEK9 gene, integrated from 9 sources (see all 38): (articles sorted by number of sources associating them with NEK9) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Purification, cloning, and characterization of Nek8, a novel NIMA- related kinase, and its candidate substrate Bicd2. (PubMed id 11864968)1, 2, 3, 9 Holland P.M.... Virca G.D. (2002)
- An autoinhibitory tyrosine motif in the cell-cycle-re gulated Nek7 kinase is released through binding of Nek9. (PubMed id 19941817)1, 2, 9 Richards M.W....Bayliss R. (2009)
- The NIMA-family kinase Nek6 phosphorylates the kinesin Eg5 at a novel site necessary for mitotic spindle formation. (PubMed id 19001501)1, 2 Rapley J....Roig J. (2008)
- Nek9, a novel FACT-associated protein, modulates interphase progression. (PubMed id 14660563)1, 2 Tan B.C.-M. and Lee S.-C. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and analysis of human chromosome 14. (PubMed id 12508121)1, 2 Heilig R.... Weissenbach J. (2003)
- A mitotic cascade of NIMA family kinases. Nercc1/Nek9 activates the Nek6 and Nek7 kinases. (PubMed id 12840024)1, 2 Belham C....Avruch J. (2003)
- Nercc1, a mammalian NIMA-family kinase, binds the Ran GTPase and regulates mitotic progression. (PubMed id 12101123)1, 2 Roig J.... Avruch J. (2002)
- Characterization of size-fractionated cDNA libraries generated by the in vitro recombination-assisted method. (PubMed id 12056414)1, 2 Ohara O.... Koseki H. (2002)
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
|
External Searches for NEK9 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing NEK9 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NEK9 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing NEK9 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for NEK9 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for NEK9 gene: Search GeneIP for patents involving NEK9
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for NEK9 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | OriGene Antibodies for NEK9 | | OriGene shRNA RFP for NEK9 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NEK9 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NEK9 | | OriGene Protein Over-expression Lysate for NEK9 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for NEK9 | | OriGene 3'-UTR Clone for NEK9 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NEK9 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NEK9 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for NEK9 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for NEK9 | | OriGene Custom Protein Services for NEK9 | | OriGene Custom Immunoassay Development | | |
| |  |
 |
| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NEK9 | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NEK9 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NEK9 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NEK9 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NEK9 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NEK9 |
| |
 |  |  |  | |
| | | Search Tocris compounds for NEK9 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | NEK9 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NEK9 |
|  |  |  | | | ThermoFisher Antibodies for NEK9 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NEK9 |
|
|
|
|