NEK7 Gene
protein-coding GIFtS: 57
GCID: GC01P198126
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NIMA-related kinase 7(Previous name: NIMA (never in mitosis gene a)-related kinase 7 )
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Aliases
for NEK7 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| NIMA-Related Kinase 71 2 | | NIMA (Never In Mitosis Gene A)-Related Kinase 71 2 | | Never In Mitosis A-Related Kinase 72 3 | | NimA-Related Protein Kinase 72 3 | | EC 2.7.11.13 8 | | Serine/Threonine-Protein Kinase Nek72 |
Export aliases for NEK7 gene to outside databasesPrevious GC identifers: GC01P195928 GC01P193660 GC01P194592 GC01P195489 GC01P195459 GC01P194933 GC01P196392 GC01P169281 |
Summaries
for NEK7 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for NEK7:
NIMA-related kinases share high amino acid sequence identity with the gene product of the Aspergillus nidulans 'neverin mitosis A' gene, which controls initiation of mitosis.(supplied by OMIM, Jul 2002)
UniProtKB/Swiss-Prot: NEK7_HUMAN, Q8TDX7Function: Protein kinase which plays an important role in mitotic cell cycle progression. Required for microtubulenucleation activity of the centrosome, robust mitotic spindle formation and cytokinesis. Phosphorylates RPS6KB1
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Genomic Views
for NEK7 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004487.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the NEK7 gene promoter:
POU2F2 (Oct-2.1) Oct-B1 ISGF-3 oct-B3 oct-B2 POU2F2 GATA-1 POU2F1 POU2F1a POU2F2B
Other transcription factors
Search SABiosciences Chromatin IP Primers for NEK7
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NEK7 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q31.3 Ensembl cytogenetic band: 1q31.3 HGNC cytogenetic band: 1q31.3NEK7 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P198126: view genomic region
(about GC identifiers)
Start:
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198,126,093 bp from pter |
End:
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198,291,550 bp from pter |
Size:
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165,458 bases |
Orientation:
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plus strand |
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Proteins
for NEK7 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NEK7_HUMAN, Q8TDX7 (See
protein sequence)Recommended Name: Serine/threonine-protein kinase Nek7 Size: 302 amino acids; 34551 Da
Cofactor: Magnesium
Subunit: Monomer. Interacts with NEK9
Subcellular location: Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, centrosome.Note=Present at centrosome throughout the cell cycle. Also detected at spindle midzone of the anaphase cells andeventually concentrates at the midbody
2 PDB 3D structures from  and Proteopedia  for NEK7:2WQM (3D)
2WQN (3D)
Secondary accessions: A6NGT8Alternative splicing: 2 isoforms: Q8TDX7-1 Q8TDX7-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for NEK7: NX_Q8TDX7
Post-translational modifications:
Phosphorylation at Ser-195 required for its activation1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8TDX7
4/7 DME Specific Peptides for NEK7 (Q8TDX7) (see all 7)
NEK7 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_598001.1
ENSEMBL proteins: ENSP00000356355 ENSP00000392745 ENSP00000444621 ENSP00000356353 ENSP00000439095 ENSP00000375835 Reactome Protein details: Q8TDX7
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
NEK7 for ontologies About GeneDecksing
NEK7 Antibody Products:
Assay Products for NEK7: |
Protein
Domains /
Families
for NEK7 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NEK7 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry Q8TDX7ProtoNet protein and cluster: Q8TDX7 UniProtKB/Swiss-Prot: NEK7_HUMAN, Q8TDX7Domain: Displays an autoinhibited conformation: Tyr-97 side chain points into the active site, interacts with theactivation loop, and blocks the alphaC helix. The autoinhibitory conformation is released upon binding with NEK9Domain: The NTE (N-terminal extension) motif is a structural component of the catalytic domain and thus contributes toactivitySimilarity: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamilySimilarity: Contains 1 protein kinase domain |
Function
for NEK7 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: NEK7_HUMAN, Q8TDX7Function: Protein kinase which plays an important role in mitotic cell cycle progression. Required for microtubulenucleation activity of the centrosome, robust mitotic spindle formation and cytokinesis. Phosphorylates RPS6KB1Catalytic activity: ATP + a protein = ADP + a phosphoproteinEnzyme regulation: Binding to NEK9 stimulates its activity by releasing the autoinhibitory function of Tyr-97Enzyme Number (IUBMB): EC 2.7.11.11 2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NEK7 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NEK7 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NEK7 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004672 | protein kinase activity |
-- | -- | | GO:0004674 | protein serine/threonine kinase activity |
ISS | -- | | GO:0005524 | ATP binding |
IEA | -- | | GO:0016772 | transferase activity, transferring phosphorus-containing groups |
-- | -- | | GO:0046872 | metal ion binding |
IEA | -- |
NEK7 for ontologies About GeneDecksing
6 GenomeRNAi human phenotypes for NEK7:
Animal Models:
Mouse knock-out Nek7tm1Mot for NEK7
4 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Nek7):
NEK7 for phenotypes About GeneDecksing
|
Pathways & Interactions
for NEK7 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Clearance of Nuclear Envelope Membranes from Chromatin | | | 2 | M Phase | | | 3 | Cell Cycle | | | 4 | Cell Cycle / Checkpoint Control | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Cell Signaling Technology (CST) Pathway for NEK7
5/7 
Reactome Pathways for NEK7 (see all 7)
NEK7 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NEK7
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
2 Interacting proteins for NEK7 (Q8TDX73 ENSP000003563554) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
NEK7 for ontologies About GeneDecksing
|
Drugs & Compounds
for NEK7 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for NEK7
3 HMDB Compounds for NEK7 About this table
Search CenterWatch for drugs/clinical trials and news about NEK7
|
Transcripts
for NEK7 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for NEK7 gene: NM_133494.2 Unigene Clusters for NEK7: NIMA-related kinase 7 Hs.24119 [show with all ESTs], Hs.744122 [show with all ESTs]Unigene Representative Sequences: BC043003, NM_1334948 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000367385(uc001gun.4 uc021pgx.1) ENST00000442588 ENST00000538004
ENST00000367383 ENST00000544035 ENST00000417895 ENST00000391974 ENST00000493790
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NEK7 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NEK7 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: NEK7 (NM_133494) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NEK7 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NEK7 |
Additional cDNA sequence: AB062450.1 AK313411.1 AL080111.1 8 DOTS entries: DT.213680 DT.100022128 DT.100776055 DT.99993701 DT.121364292 DT.95272718 DT.95272719 DT.121364319 24/204 AceView cDNA sequences (see all 204): BM783345 AW262762 AI696961 BQ022852 BM543219 BM468972 AA506352 AA385867 CD677193 BQ014574 AW339206 BQ023360 AA102848 AA330074 BQ774293 CB241962 AA280996 BM974979 AI279412 BG057502 AW771141 BF057667 AA972531 BQ023934
GeneLoc Exon Structure
|
Expression
for NEK7 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NEK7 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AATGCTTTAC
About this image
See NEK7 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NEK7
SOURCE GeneReport for Unigene clusters: Hs.24119 Hs.744122
UniProtKB/Swiss-Prot: NEK7_HUMAN, Q8TDX7Tissue specificity: Highly expressed in lung, muscle, testis, brain, heart, liver, leukocyte and spleen. Lowerexpression in ovary, prostate and kidney. No expression seen in small intestine
SABiosciences Custom PCR Arrays for NEK7
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NEK7
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NEK7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NEK7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NEK7 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NEK7 |
Orthologs
for NEK7 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for NEK7 gene from 4/16 species (see all 16) About this table
ENSEMBL Gene Tree for NEK7 (if available)
TreeFam Gene Tree for NEK7 (if available) |
Paralogs
for NEK7 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for NEK7 gene
- NEK42 NEK62 NEK12 NEK112 NEK32 NEK52 NEK22 NEK82
- NEK102 NEK92
18/49 SIMAP similar genes for NEK7 using alignment to 4 protein entries: NEK7_HUMAN (see all proteins)
(see all similar genes):NEK6 NEK1 NEK8 NEK11 NEK5 NEK2
NEK4 NEK10 NEK3 DKFZp434B079 NEK9 STK25
YSK4 MAP2K3 MAP3K19 MAP3K2 MAP3K4 OXSR1
NEK7 for paralogs About GeneDecksing
|
Genomic Variants
for NEK7 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for NEK7 (198126093 - 198291550 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for NEK7
1 CNV: 97608 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NEK7 |
|
Disorders
/ Diseases
for NEK7 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NEK7 for disorders About GeneDecksing
OMIM gene information: 606848
OMIM disorders: --
6  diseases for NEK7: About MalaCardspolycystic kidney disease kidney disease pancreatic cancer breast cancer
pancreatitis prostatitis
Human Genome Epidemiology (HuGE) Navigator: NEK7 (2 documents)
Export disorders for NEK7 gene to outside databases
|
Publications
for NEK7 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NEK7 gene, integrated from 9 sources (see all 22):
(articles sorted by number of sources associating them with NEK7) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification and assignment of the human NIMA-related protein kinase 7 gene (NEK7) to human chromosome 1q31.3. (PubMed id 11701951)1, 2, 3, 9 Kimura M. and Okano Y. (2001)
- The Nek6 and Nek7 protein kinases are required for ro bust mitotic spindle formation and cytokinesis. (PubMed id 19414596)1, 2 O'Regan L. and Fry A.M. (2009)
- An autoinhibitory tyrosine motif in the cell-cycle-re gulated Nek7 kinase is released through binding of Nek9. (PubMed id 19941817)1, 2 Richards M.W....Bayliss R. (2009)
- Mitotic regulation by NIMA-related kinases. (PubMed id 17727698)1, 2 O'regan L.... Fry A.M. (2007)
- NEK7 is a centrosomal kinase critical for microtubule nucleation. (PubMed id 17586473)1, 2 Kim S....Rhee K. (2007)
- Nek7 kinase is enriched at the centrosome, and is required for proper spindle assembly and mitotic progression. (PubMed id 17101132)1, 2 Yissachar N....Motro B. (2006)
- A mitotic cascade of NIMA family kinases. Nercc1/Nek9 activates the Nek6 and Nek7 kinases. (PubMed id 12840024)1, 2 Belham C....Avruch J. (2003)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Human Nek6 is a monomeric mostly globular kinase with an unfolded short N-terminal domain. (PubMed id 21320329)2 Meirelles G.V.... Kobarg J. (2011)
|
External Searches for NEK7 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing NEK7 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NEK7 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NEK7 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for NEK7 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for NEK7 gene:
Search GeneIP for patents involving NEK7
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for NEK7 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for NEK7 | | OriGene shRNA RFP for NEK7 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NEK7 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NEK7 | | | OriGene Protein Over-expression Lysate for NEK7 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for NEK7 | | OriGene 3'-UTR Clone for NEK7 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NEK7 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NEK7 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for NEK7 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for NEK7 | | OriGene Custom Protein Services for NEK7 | | | OriGene Custom Immunoassay Development | | |
| |
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 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NEK7 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NEK7 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NEK7 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NEK7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NEK7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NEK7 |
| |
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| | Antibodies & Assays for NEK7 |
| | | | Search Tocris compounds for NEK7 |
| |  |  |  |  | | | | |
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 |
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 | | | NEK7 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NEK7 |
|  |  |  | | | | ThermoFisher Antibody for NEK7 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NEK7 |
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