Aliases for NEK7 Gene
External Ids for NEK7 Gene
Previous GeneCards Identifiers for NEK7 Gene
NIMA-related kinases share high amino acid sequence identity with the gene product of the Aspergillus nidulans 'never in mitosis A' gene, which controls initiation of mitosis.[supplied by OMIM, Jul 2002]
GeneCards Summary for NEK7 Gene
NEK7 (NIMA Related Kinase 7) is a Protein Coding gene. Diseases associated with NEK7 include Gallbladder Cancer. Among its related pathways are Regulation of Glucokinase by Glucokinase Regulatory Protein and Cell Cycle, Mitotic. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is NEK6.
UniProtKB/Swiss-Prot for NEK7 Gene
Protein kinase which plays an important role in mitotic cell cycle progression. Required for microtubule nucleation activity of the centrosome, robust mitotic spindle formation and cytokinesis. Phosphorylates RPS6KB1.