Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



NEK5 Gene

protein-coding   GIFtS: 41
GCID: GC13M052610

NIMA-Related Kinase 5

(Previous name: NIMA (never in mitosis gene a)-related kinase 5)
  Search for NEK5
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
NIMA-Related Kinase 51 2     EC 2.7.11.13 8
NIMA (Never In Mitosis Gene A)-Related Kinase 51 2     Serine/Threonine-Protein Kinase Nek52
Never In Mitosis A-Related Kinase 52 3     EC 2.7.118
NimA-Related Protein Kinase 52 3     

External Ids:    HGNC: 77481   Entrez Gene: 3416762   Ensembl: ENSG000001971687   UniProtKB: Q6P3R83   

Export aliases for NEK5 gene to outside databases

Previous GC identifers: GC13U990078 GC13M051537 GC13M033427


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for NEK5 Gene:
NEK5 (NIMA-related kinase 5) is a protein-coding gene. GO annotations related to this gene include protein serine/threonine kinase activity. An important paralog of this gene is NEK4.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
Regulatory elements:
   Regulatory transcription factor binding sites in the NEK5 gene promoter:
         FOXF2   Tal-1   Pbx1a   Nkx2-2   MyoD   E47   POU2F1   POU2F1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNEK5 promoter sequence
   Search Chromatin IP Primers for NEK5

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NEK5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q14.3   Ensembl cytogenetic band:  13q14.3   HGNC cytogenetic band: 13q14.2

NEK5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NEK5 gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13M052610:  view genomic region     (about GC identifiers)

Start:
52,611,093 bp from pter      End:
52,703,214 bp from pter
Size:
92,122 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: NEK5_HUMAN, Q6P3R8 (See protein sequence)
Recommended Name: Serine/threonine-protein kinase Nek5  
Size: 708 amino acids; 81445 Da
Cofactor: Magnesium (By similarity)
Secondary accessions: Q5TAP5

Explore the universe of human proteins at neXtProt for NEK5: NX_Q6P3R8

Explore proteomics data for NEK5 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • 2 DME Specific Peptides for NEK5 (Q6P3R8)
     SPRDRPSI  GTPYYLSPE 


    See NEK5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_954983.1  
    ENSEMBL proteins: 
     ENSP00000431956   ENSP00000347767  

    NEK5 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for NEK5
    OriGene Custom MassSpec
    OriGene Custom Protein Services for NEK5
    GenScript Custom Purified and Recombinant Proteins Services for NEK5
    Novus Biologicals NEK5 Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for NEK5

    NEK5 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for NEK5
    OriGene Custom Antibody Services for NEK5
    Novus Biologicals NEK5 Antibodies
    Abcam antibodies for NEK5
    Cloud-Clone Corp. Antibodies for NEK5
    Search ThermoFisher Antibodies for NEK5
    LSBio Antibodies in human, mouse, rat for NEK5

    NEK5 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for NEK5
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for NEK5
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for NEK5
    Cloud-Clone Corp. CLIAs for NEK5


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    IUPHAR Guide to PHARMACOLOGY protein family classification: NIMA-related kinase 5
    NIMA (never in mitosis gene a)- related kinase (NEK) family

    5 InterPro protein domains:
     IPR017441 Protein_kinase_ATP_BS
     IPR002290 Ser/Thr_dual-sp_kinase_dom
     IPR011009 Kinase-like_dom
     IPR008271 Ser/Thr_kinase_AS
     IPR000719 Prot_kinase_dom

    Graphical View of Domain Structure for InterPro Entry Q6P3R8

    ProtoNet protein and cluster: Q6P3R8

    UniProtKB/Swiss-Prot: NEK5_HUMAN, Q6P3R8
    Similarity: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily
    Similarity: Contains 1 protein kinase domain


    NEK5 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NEK5_HUMAN, Q6P3R8
    Catalytic activity: ATP + a protein = ADP + a phosphoprotein

         Enzyme Numbers (IUBMB): EC 2.7.11.11 2 EC 2.7.112

         Gene Ontology (GO): Selected molecular function terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004672protein kinase activity ----
    GO:0004674protein serine/threonine kinase activity IEA--
    GO:0004713protein tyrosine kinase activity ----
    GO:0005524ATP binding IEA--
    GO:0016772transferase activity, transferring phosphorus-containing groups ----
         
    NEK5 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for NEK5:
     Decreased Salmonella enterica  

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NEK5
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for NEK5

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NEK5
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NEK5

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat NEK5 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate NEK5
    SwitchGear 3'UTR luciferase reporter plasmidNEK5 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for NEK5
    Predesigned siRNA for gene silencing in human, mouse, rat NEK5

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for NEK5

    Clone
    Products:
         
    OriGene clones in human, mouse for NEK5 (see all 8)
    OriGene ORF clones in mouse, rat for NEK5
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NEK5 (NM_199289)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NEK5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NEK5

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for NEK5
    Browse ESI BIO Cell Lines and PureStem Progenitors for NEK5 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NEK5


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    cytoskeleton1
    mitochondrion1
    nucleus1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NEK5
    Interactions:

        Search GeneGlobe Interaction Network for NEK5

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for NEK5 (ENSP000003477674) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    WWTR1ENSP000003538474STRING: ENSP00000353847
    YAP1ENSP000002824414STRING: ENSP00000282441
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006468protein phosphorylation ----

    NEK5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NEK5

    3 HMDB Compounds for NEK5    About this table
    CompoundSynonyms CAS #PubMed Ids
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    MagnesiumMagnesium (see all 2)7439-95-4--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for NEK5 gene: 
    NM_199289.1  

    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000529080 ENST00000465811 ENST00000355568(uc001vge.3)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat NEK5 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate NEK5
    SwitchGear 3'UTR luciferase reporter plasmidNEK5 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for NEK5
    Predesigned siRNA for gene silencing in human, mouse, rat NEK5
    Clone
    Products:
         
    OriGene clones in human, mouse for NEK5 (see all 8)
    OriGene ORF clones in mouse, rat for NEK5
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NEK5 (NM_199289)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NEK5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NEK5
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for NEK5
    OriGene qSTAR qPCR primer pairs in human, mouse for NEK5
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NEK5
      QuantiTect SYBR Green Assays in human, mouse, rat NEK5
      QuantiFast Probe-based Assays in human, mouse, rat NEK5

    13 AceView cDNA sequences:

    CR598570 BC063885 BX342707 AW002801 BX350584 BX417448 AW173561 AK126330 
    BX328262 CD243608 CD700193 CD705373 BX342706 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    NEK5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    NEK5 Expression
    About this image

    NEK5 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NEK5 Protein Expression
        Custom PCR Arrays for NEK5
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for NEK5
    OriGene qSTAR qPCR primer pairs in human, mouse for NEK5
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NEK5
    QuantiTect SYBR Green Assays in human, mouse, rat NEK5
    QuantiFast Probe-based Assays in human, mouse, rat NEK5
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NEK5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for NEK5 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nek51 , 5 NIMA (never in mitosis gene a)-related expressed kinase 5 less1, 5 79.65(n)1
    72.69(a)1
      8 (10.95 cM)5
    3307211  NM_177898.41  NP_808566.21 
     220736165 
    chicken
    (Gallus gallus)
    Aves NEK51 NIMA (never in mitosis gene a)-related kinase 5 64.38(n)
    55.73(a)
      418881  XM_004938726.1  XP_004938783.1 
    lizard
    (Anolis carolinensis)
    Reptilia NEK56
    NIMA-related kinase 5
    52(a)
    1 ↔ 1
    1(132765220-132791093)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.151912 Xenopus laevis transcribed sequence with weak similarity to protein spP51956 (H.sapiens) NEK3_HUMAN Serine/threonine-protein kinase NEK3 (NimA-related protein kinase 3) (HSPK 36) less 76.18(n)    BJ061491.1 
    zebrafish
    (Danio rerio)
    Actinopterygii NEK56
    NIMA-related kinase 5
    59(a)
    1 ↔ 1
    9(58050126-58052178) ENSDARG00000079685


    ENSEMBL Gene Tree for NEK5 (if available)
    TreeFam Gene Tree for NEK5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for NEK5 gene
    NEK42  NEK62  NEK12  NEK112  NEK32  NEK72  NEK22  NEK82  
    NEK102  NEK92  
    Selected SIMAP similar genes for NEK5 using alignment to 2 protein entries:     NEK5_HUMAN (see all proteins) (see all similar genes):
    NEK3    DKFZp434B079    RPS6KA3    MARK4    NEK6    NEK7
    KIN27    NEK2    PRKACB    PRKAA1    STK17A    PAK4
    MYO3A    AURKC    MST094    NUAK1    TSSK6    CDK1

    NEK5 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for NEK5 (see all 1252)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 13 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs128776011,2
    C--52638460(+) ctgccC/Tggcca 1 -- int10--------
    rs44442301,2
    C--52638622(+) ccgtcC/Tgggag 1 -- int10--------
    rs1900158701,2
    --52638650(+) CCCCCC/TGCCTG 1 -- int10--------
    rs1126933151,2
    C--52638742(+) ACCACC/TCTGTC 1 -- int10--------
    rs95358491,2
    C,A--52639131(+) gccacA/Tgggtc 1 -- ut311Minor allele frequency- T:0.00NA 2
    rs1456043101,2
    --52639155(+) AACCAC/GAGACC 1 -- ut310--------
    rs1404234671,2
    --52639178(+) TTTATC/TTGCTG 1 -- ut310--------
    rs1857201501,2
    --52639230(+) CTCTGC/TGAGAA 1 -- ut310--------
    rs1454374501,2
    C--52639231(+) TCTGCA/GAGAAA 1 -- ut310--------
    rs1923175871,2
    --52639261(+) AAAAAC/TAAAAA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for NEK5 (52611093 - 52703214 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for NEK5:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2549303CNV Deletion19546169
    esv2747424CNV Deletion23290073
    esv2747423CNV Deletion23290073
    nsv900082CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NEK5
    DNA2.0 Custom Variant and Variant Library Synthesis for NEK5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for NEK5 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with NEK5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)1, 2 Dunham A.... Ross M.T. (Nature 2004)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. The NIMA kinase: a mitotic regulator in Aspergillus nidulans and vertebrate cells. (PubMed id 9552363)1, 3 Lu K.P. and Hunter T. (Prog Cell Cycle Res 1995)
    4. Patterns of somatic mutation in human cancer genomes. (PubMed id 17344846)2 Greenman C.... Stratton M.R. (Nature 2007)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 341676 HGNC: 7748 AceView: MGC75495 Ensembl:ENSG00000197168 euGenes: HUgn341676
    ECgene: NEK5 H-InvDB: NEK5

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for NEK5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for NEK5 gene:
    Search GeneIP for patents involving NEK5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for NEK5   OriGene RNAi products in human, mouse, rat for NEK5  
     OriGene qPCR primer pairs and template standards for NEK5   OriGene Protein Over-expression Lysate for NEK5  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for NEK5  
     OriGene qSTAR qPCR primer pairs in human, mouse for NEK5   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for NEK5   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for NEK5   OriGene Custom Protein Services for NEK5  

     
     
     Block miRNA regulation of human, mouse, rat NEK5 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing NEK5
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NEK5 Predesigned siRNA for gene silencing in human, mouse, rat NEK5
     QuantiFast Probe-based Assays in human, mouse, rat NEK5 QuantiTect SYBR Green Assays in human, mouse, rat NEK5
     Custom PCR Arrays for NEK5 Search Chromatin IP Primers for NEK5
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NEK5  Search GeneGlobe Interaction Network for NEK5
     Regulatory tfbs in NEK5 promoter
     GenScript Custom Purified and Recombinant Proteins Services for NEK5 GenScript cDNA clones with any tag delivered in your preferred vector for NEK5
     GenScript Custom Assay Services for NEK5 GenScript Custom overexpressing Cell Line Services for NEK5
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for NEK5
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     NEK5 antibodies
     NEK5 proteins
     Antibodies for NEK5
     See all of Abcam's Antibodies, Kits and Proteins for NEK5
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for NEK5
     Antibodies for NEK5
     ELISAs for NEK5
     CLIAs for NEK5



     Browse ESI BIO Cell Lines and PureStem Progenitors for NEK5
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NEK5
     SwitchGear 3'UTR luciferase reporter plasmids for NEK5
     SwitchGear Promoter luciferase reporter plasmids for NEK5
     Search ThermoFisher Antibodies for NEK5
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NEK5
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NEK5
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for NEK5
     LSBio Antibodies in human, mouse, rat for NEK5
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      NEK5 gene at Home site.
    Version: 3.12.166 28 Aug 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4