Aliases for NEK4 Gene
External Ids for NEK4 Gene
Previous HGNC Symbols for NEK4 Gene
Previous GeneCards Identifiers for NEK4 Gene
GeneCards Summary for NEK4 Gene
NEK4 (NIMA Related Kinase 4) is a Protein Coding gene. Diseases associated with NEK4 include Meckel Syndrome 1. Among its related pathways are Sweet Taste Signaling. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is NEK1.
UniProtKB/Swiss-Prot for NEK4 Gene
Protein kinase that seems to act exclusively upon threonine residues (By similarity). Required for normal entry into proliferative arrest after a limited number of cell divisions, also called replicative senescence. Required for normal cell cycle arrest in response to double-stranded DNA damage.