NEK4 Gene
protein-coding GIFtS: 56
GCID: GC03M052719
|
|
NIMA-related kinase 4(Previous names: serine/threonine kinase 2, NIMA (never in mitosis gene...)
(Previous symbol: STK2)
| |
Aliases
for NEK4 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| NIMA-Related Kinase 41 2 | | NimA-Related Protein Kinase 42 3 | | STK21 2 3 5 | | Serine/Threonine-Protein Kinase 22 3 | | NRK21 2 5 | | Serine/Threonine-Protein Kinase NRK22 3 | | NIMA (Never In Mitosis Gene A)-Related Kinase 41 2 | | EC 2.7.11.13 8 | | Pp123011 | | Serine/Threonine Protein Kinase-22 | | Serine/Threonine Kinase 21 2 | | Serine/Threonine-Protein Kinase Nek42 | | Never In Mitosis A-Related Kinase 42 3 | | EC 2.7.118 |
Export aliases for NEK4 gene to outside databasesPrevious GC identifers: GC03M051836 GC03M051996 GC03M052599 GC03M052702 |
Summaries
for NEK4 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: NEK4_HUMAN, P51957Function: Seems to act exclusively upon threonine residues (By similarity)
|
Genomic Views
for NEK4 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_022517.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the NEK4 gene promoter:
GR Pax-5 MIF-1 Evi-1 MEF-2A CREB deltaCREB POU2F1a aMEF-2 GR-alpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for NEK4
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NEK4 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3p21.1 Ensembl cytogenetic band: 3p21.1 HGNC cytogenetic band: 3p21.1NEK4 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03M052719: view genomic region
(about GC identifiers)
Start:
|
52,744,796 bp from pter |
End:
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52,804,965 bp from pter |
Size:
|
60,170 bases |
Orientation:
|
minus strand |
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Proteins
for NEK4 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NEK4_HUMAN, P51957 (See
protein sequence)Recommended Name: Serine/threonine-protein kinase Nek4 Size: 841 amino acids; 94597 Da
Cofactor: Magnesium (By similarity)
Subcellular location: Nucleus (Probable)
Secondary accessions: A5YM70 B2R633 B7Z200 Q6P576Alternative splicing: 3 isoforms: P51957-1 P51957-2 P51957-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for NEK4: NX_P51957
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P51957
2 DME Specific Peptides for NEK4 (P51957)
NEK4 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001180462.1 NP_003148.2
ENSEMBL proteins: ENSP00000233027 ENSP00000373227 ENSP00000419666 ENSP00000420231 ENSP00000417119 ENSP00000437703
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
NEK4 for ontologies About GeneDecksing
NEK4 Antibody Products:
Assay Products for NEK4: |
Protein
Domains /
Families
for NEK4 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NEK4 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P51957ProtoNet protein and cluster: P51957 UniProtKB/Swiss-Prot: NEK4_HUMAN, P51957Similarity: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamilySimilarity: Contains 1 protein kinase domain |
Function
for NEK4 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: NEK4_HUMAN, P51957Function: Seems to act exclusively upon threonine residues (By similarity)Catalytic activity: ATP + a protein = ADP + a phosphoproteinEnzyme Numbers (IUBMB): EC 2.7.11.11 2 EC 2.7.112
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NEK4 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NEK4 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): NEK4 (NM_003157) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NEK4 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NEK4 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NEK4 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004674 | protein serine/threonine kinase activity |
IEA | -- | | GO:0005524 | ATP binding |
IEA | -- | | GO:0046872 | metal ion binding |
IEA | -- |
NEK4 for ontologies About GeneDecksing
4 GenomeRNAi human phenotypes for NEK4:
Animal Models:
1 MGI phenotypic allele  for Nek4 (no phenotypes)
NEK4 for phenotypes About GeneDecksing
|
Pathways & Interactions
for NEK4 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Sweet Taste Signaling | |
1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for NEK4
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NEK4
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
NEK4 for ontologies About GeneDecksing
|
Drugs & Compounds
for NEK4 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for NEK4
3 HMDB Compounds for NEK4 About this table
Search CenterWatch for drugs/clinical trials and news about NEK4
|
Transcripts
for NEK4 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for NEK4 gene (2 alternative transcripts): NM_001193533.1 NM_003157.4 Unigene Cluster for NEK4: NIMA-related kinase 4 Hs.631921 [show with all ESTs]Unigene Representative Sequence: NM_0031577 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000233027(uc003dfq.4 uc011bej.2) ENST00000383721(uc003dfr.3)
ENST00000461689 ENST00000493199 ENST00000487068 ENST00000496822 ENST00000535191
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NEK4 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NEK4 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): NEK4 (NM_003157) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NEK4 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NEK4 |
Additional cDNA sequence: AK294165.1 AK312420.1 BC015515.1 BC063044.1 EF560744.1 L20321.1 11 DOTS entries: DT.100792406 DT.412966 DT.100743995 DT.100792403 DT.120884085 DT.120884093 DT.120884143 DT.40106034 DT.86839863 DT.92427734 DT.95356092 24/131 AceView cDNA sequences (see all 131): BX282416 AA888344 BE889895 AA205125 BM748481 BP355774 CA418230 AA678151 BQ212584 BM719078 AA886466 AI561033 BP351736 BF983881 AA382899 BC015515 BU186968 BX377921 AL044912 BM713549 CB159682 AA442692 CB120617 BE670907
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for NEK4 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | ^ | 15 | ^ | 16 | ^ | 17a | · | 17b | ^ | 18 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | - | | | | | | | | - | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | - | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for NEK4
|
Expression
for NEK4 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NEK4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGGTCCTCTG
About this image
See NEK4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NEK4
SOURCE GeneReport for Unigene cluster: Hs.631921
UniProtKB/Swiss-Prot: NEK4_HUMAN, P51957Tissue specificity: Highest expression in adult heart, followed by pancreas, skeletal muscle, brain, liver, kidney,lung and placenta. Present in most primary carcinomas
SABiosciences Custom PCR Arrays for NEK4
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NEK4
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NEK4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NEK4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NEK4 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NEK4 |
Orthologs
for NEK4 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for NEK4 gene from 6/25 species (see all 25) About this table
ENSEMBL Gene Tree for NEK4 (if available)
TreeFam Gene Tree for NEK4 (if available) |
Paralogs
for NEK4 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for NEK4 gene
- NEK62 NEK12 NEK112 NEK32 NEK72 NEK52 NEK22 NEK82
- NEK102 NEK92
18/112 SIMAP similar genes for NEK4 using alignment to 5 protein entries: NEK4_HUMAN (see all proteins)
(see all similar genes):TGM4 FLJ00047 C1orf143 EIF3G pp12301 EEF1E1
RHOA EIF3K C10orf137 FAM3A KIAA0101 MLL5
TMEM14B TNFRSF17 UBE2V2 ABI2 CALCOCO2 NPLOC4
NEK4 for paralogs About GeneDecksing
5 Pseudogenes.org Pseudogenes for NEK4
PGOHUM00000238818 PGOHUM00000236930 PGOHUM00000236935 PGOHUM00000239040 PGOHUM00000249510
|
Genomic Variants
for NEK4 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for NEK4 (52744796 - 52804965 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for NEK4
1 CNV: 4339 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NEK4 |
|
Disorders
/ Diseases
for NEK4 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NEK4 for disorders About GeneDecksing
OMIM gene information: 601959
OMIM disorders: --
5  diseases for NEK4: About MalaCardscoffin-lowry syndrome bipolar disorder retinitis malaria
carcinoma
1 disease from the University of Copenhagen DISEASES database for NEK4:Coffin-Lowry syndrome Human Genome Epidemiology (HuGE) Navigator: NEK4 (4 documents)
Export disorders for NEK4 gene to outside databases
|
Publications
for NEK4 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NEK4 gene, integrated from 9 sources (see all 20):
(articles sorted by number of sources associating them with NEK4) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Two novel human serine/threonine kinases with homologies to the cell cycle regulating Xenopus MO15, and NIMA kinases: cloning and characterization of their expression pattern. (PubMed id 8208544)1, 2, 3 Levedakou E.N.... Liu E.T. (1994)
- Nek4 regulates entry into replicative senescence and t he response to DNA damage in human fibroblasts. (PubMed id 22851694)1 Nguyen C.L....Hahn W.C. (2012)
- Large-scale genome-wide association analysis of bipol ar disorder identifies a new susceptibility locus near ODZ4. (PubMed id 21926972)1 Sklar P....Purcell S.M. (2011)
- The ciliopathy-associated protein homologs RPGRIP1 an d RPGRIP1L are linked to cilium integrity through interaction with Nek4 serine/ threonine kinase. (PubMed id 21685204)1 Coene K.L....Roepman R. (2011)
- Nek4 status differentially alters sensitivity to dist inct microtubule poisons. (PubMed id 20103636)1 Doles J. and Hemann M.T. (2010)
- A large-scale candidate gene association study of age at menarche and age at natural menopause. (PubMed id 20734064)1 He C....Hunter D.J. (2010)
- Investigation of genetic susceptibility factors for h uman longevity - A targeted nonsynonymous SNP study. (PubMed id 20800603)1 Flachsbart F....Nebel A. (2010)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
- Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry. (PubMed id 19416921)1 Scott L.J....Boehnke M. (2009)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
|
External Searches for NEK4 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing NEK4 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NEK4 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NEK4 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for NEK4 gene:
Search GeneIP for patents involving NEK4
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for NEK4 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for NEK4 | | OriGene shRNA RFP for NEK4 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NEK4 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NEK4 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for NEK4 | | OriGene 3'-UTR Clone for NEK4 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NEK4 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NEK4 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for NEK4 | | OriGene Custom Protein Services for NEK4 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NEK4 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NEK4 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NEK4 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NEK4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NEK4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NEK4 |
| |
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| | | | Search Tocris compounds for NEK4 |
| |  |  |  |  | | | | |
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 |
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 | | | NEK4 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NEK4 |
|  |  |  | | | | ThermoFisher Antibodies for NEK4 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NEK4 |
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