NEK11 Gene
protein-coding GIFtS : 54
GCID: GC03 P130745
NIMA-related kinase 11 (Previous name: NIMA (never in mitosis gene a)- related kinase 11 )
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Aliasesfor NEK11 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases NIMA-Related Kinase 11 1 2 EC 2.7.11.13 NIMA (Never In Mitosis Gene A)- Related Kinase 111 2 Never In Mitosis A-Related Kinase 113 FLJ234951 NimA-Related Protein Kinase 113 Serine/Threonine-Protein Kinase Nek112 EC 2.7.118
Export aliases for NEK11 gene to outside databases Previous GC identifers: GC03P127657 GC03P131462 GC03P132027 GC03P132066 GC03P132228 GC03P128129
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Summariesfor NEK11 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for NEK11 : This gene encodes a member of the never in mitosis gene A family of kinases. The encoded protein localizes to the nucleoli, and may function with NEK2A in the S-phase checkpoint. The encoded protein appears to play roles in DNA replication and response to genotoxic stress. Alternatively spliced transcript variants have been described.(provided by RefSeq, Mar 2009) UniProtKB/Swiss-Prot: NEK11_HUMAN, Q8NG66 Function : Protein kinase which plays an important role in the G2/M checkpoint response to DNA damage. Controlsdegradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation
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Genomic Viewsfor NEK11 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000003.11 NC_018914.1 NT_005612.16 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the NEK11 gene promoter: SRF C/EBPbeta ATF-2 Nkx2-5 LCR-F1 HNF-1A GATA-2 CRE-BP1 HNF-1 Other transcription factors Search SABiosciences Chromatin IP Primers for NEK11 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat NEK11
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 3q22.1 Ensembl cytogenetic band: 3q22.1 HGNC cytogenetic band: 3q22.1 NEK11 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 3 GeneLoc Exon Structure
GeneLoc location for GC03P130745: view genomic region
(about GC identifiers )
Start:
130,745,694 bp from pter
End:
131,069,309 bp from pter
Size:
323,616 bases
Orientation:
plus strand
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Proteinsfor NEK11 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: NEK11_HUMAN, Q8NG66 (See
protein sequence )Recommended Name: Serine/threonine-protein kinase Nek11 Size : 645 amino acids; 74192 Da
Cofactor : Manganese or magnesium
Subunit : Interacts with isoform 1 of NEK2
Subcellular location : Nucleus. Nucleus, nucleolus. Note=Nuclear during interphase but moves to the polar microtubulesduring prometaphase and metaphase. Accumulates in the nucleolus in G1/S-arrested cells
Developmental stage : Predominantly expressed at S/G2/M phase
Sequence caution : Sequence=BAB15672.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions : A6NHD7 Q5JPC0 Q8NG65 Q8TBY1 Q9H5F4Alternative splicing : 4 isoforms : Q8NG66-1 Q8NG66-2 Q8NG66-3 Q8NG66-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for NEK11: NX_Q8NG66 Post-translational modifications:
Phosphorylated by NEK2. Phosphorylation at Ser-273 is important for its activation1
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q8NG66 2 DME Specific Peptides for NEK11 (Q8NG66 ) NEK11 Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins (3 alternative transcripts):
NP_001139475.1 NP_079076.3 NP_665917.1 ENSEMBL proteins: ENSP00000421549 ENSP00000423458 ENSP00000425114 ENSP00000372857 ENSP00000425662 ENSP00000421192 ENSP00000426662 ENSP00000421851 ENSP00000397180 ENSP00000349389 ENSP00000411888 Human Recombinant Protein Products: Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view) : About this table
NEK11 for ontologies About GeneDecksing NEK11 Antibody Products: Assay Products for NEK11:
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Protein
Domains / Familiesfor NEK11 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
NEK11 for domains About GeneDecksing 4 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry Q8NG66 ProtoNet protein and cluster: Q8NG66
UniProtKB/Swiss-Prot: NEK11_HUMAN, Q8NG66 Similarity : Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamilySimilarity : Contains 1 protein kinase domain
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Functionfor NEK11 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Function Summary: UniProtKB/Swiss-Prot: NEK11_HUMAN, Q8NG66 Function : Protein kinase which plays an important role in the G2/M checkpoint response to DNA damage. Controlsdegradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation Catalytic activity : ATP + a protein = ADP + a phosphoproteinEnzyme regulation : Autorepressed by intramolecular binding of the C-terminus which dissociates followingphosphorylation by NEK2 isoform 1 in G1/S-arrested cells. NEK2 isoform 2 is largely not present in the nucleolus, and does not appear to phosphorylate NEK11. Activated in response to DNA damage. Inhibited by zinc Enzyme Numbers (IUBMB): EC 2.7.11 2 EC 2.7.11.1 1
Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for NEK11 (see all 5 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for NEK11 (see all 4 )OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 3 ): NEK11 (NM_145910 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NEK11 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat NEK11
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NEK11
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view) : About this table
NEK11 for ontologies About GeneDecksing 1 GenomeRNAi human phenotype for NEK11 :
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Pathways & Interactionsfor NEK11 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NEK11 STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)2 Interacting proteins for NEK11 (Q8NG66 1 , 3 ENSP00000372857 4 ) via UniProtKB, MINT, STRING , and/or I2D About this table Gene Ontology (GO): 5 biological process terms (GO ID links to tree view) : About this table
NEK11 for ontologies About GeneDecksing
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Drugs & Compoundsfor NEK11 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for NEK11 4 HMDB Compounds for NEK11 About this table Search CenterWatch for drugs/clinical trials and news about NEK11
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Transcriptsfor NEK11 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for NEK11 gene (3 alternative transcripts): NM_001146003.1 NM_024800.4 NM_145910.3 Unigene Cluster for NEK11:
NIMA-related kinase 11 Hs.657336 [show with all ESTs ] Unigene Representative Sequence: NM_024800 18 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000510769 ENST00000506695 (uc003enw.1 uc011blm.2 ) ENST00000510688 ENST00000511262 (uc003enx.3 ) ENST00000383366 (uc003eny.3 ) ENST00000513550 ENST00000514915 ENST00000510474 ENST00000507967 ENST00000507910 ENST00000508196 ENST00000426022 ENST00000510926 ENST00000515636 ENST00000510823 ENST00000429253 (uc003eoa.3 uc003enz.3 uc011blk.2 uc011bll.2 )ENST00000356918 (uc010hto.2 ) ENST00000412440 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for NEK11 (see all 5 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for NEK11 (see all 4 )OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 3 ): NEK11 (NM_145910 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NEK11 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat NEK11
Additional cDNA sequence: AB071996.1 AB071997.1 AK027148.1 AK123021.1 AK293261.1 AK297300.1 AK316352.1 AL833472.1 BC009414.1 BC026195.1 BC028587.2
12 DOTS entries : DT.412911 DT.99940186
DT.101980867 DT.100741330 DT.99971845 DT.92421362 DT.100741329 DT.100747846 DT.100776052 DT.100776053 DT.65285662 DT.97828907 24/71 AceView cDNA sequences (see all 71 ):
AK027148 BI962897 CR599596 BC028587 AA393085 BX365473 AI288082 BQ002569 AK123021 CD106568 AB071997 NM_145910 BU622115 AL833472 AW027268 CK903564 AI057303 AI017033 BC009414 BI544364 AI284257 BG185510 CD557726 AW299861 GeneLoc Exon Structure 3 Alternative Splicing Database (ASD) splice patterns (SP) for NEK11 About this scheme ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 SP1 :               -                 -           SP2 :               -                           SP3 :                                        
ECgene alternative splicing isoforms for NEK11
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Expression for NEK11 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section NEK11 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: ACTAATAAGG
About this image NEK11 expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table Stem Cell Differentiation: 1 LifeMap Cell Name Category Posterior foregut-like cells (A scalable, suspensi... )Expression: Positive Negative
Selective markerExperimental details:
Curated
Microarrays
In-situ hybridization
See NEK11 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for NEK11 SOURCE GeneReport for Unigene cluster: Hs.657336 UniProtKB/Swiss-Prot: NEK11_HUMAN, Q8NG66 Tissue specificity : Poorly expressed in cerebellum, trachea, lung, appendix, and uterus SABiosciences Custom PCR Arrays for NEK11 Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for NEK11Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat NEK11 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat NEK11 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat NEK11 In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NEK11
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Orthologsfor NEK11 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of chordates.
Orthologs for NEK11 gene from 3/20 species (see all 20 ) About this table
ENSEMBL Gene Tree for NEK11 (if available)TreeFam Gene Tree for NEK11 (if available)
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Paralogsfor NEK11 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for NEK11 gene NEK4 2 NEK6 2 NEK1 2 NEK3 2 NEK7 2 NEK5 2 NEK2 2 NEK8 2 NEK10 2 NEK9 2 18/24 SIMAP similar genes for NEK11 using alignment to 5 protein entries: NEK11_HUMAN (see all proteins )
(see all similar genes ):DKFZp564L2416 ABL1 NEK7 RPS6KA3 NEK6 NEK3 DKFZp434B079 MST094 NEK10 NEK5 CHEK2 RPS6KA2 STK11 HUNK NEK4 PRKACB STK36 MYO3A
NEK11 for paralogs About GeneDecksing
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Genomic Variantsfor NEK11 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 3 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for NEK11 (130745694 - 130995694 bp, first 250kb of NEK11)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 2 variations for NEK11 2 CNVs : 36064 91553
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing NEK11
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Disorders
/ Diseasesfor NEK11 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
NEK11 for disorders About GeneDecksing
OMIM gene information: 609779
OMIM disorders : --1 disease for NEK11 : About MalaCards malaria Human Genome Epidemiology (HuGE) Navigator: NEK11 (3 documents) Export disorders for NEK11 gene to outside databases
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Publicationsfor NEK11 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for NEK11 gene, integrated from 9 sources (see all 16 ): (articles sorted by number of sources associating them with NEK11) Utopia : connect your pdf to the dynamic world of online information
Nek11, a new member of the NIMA family of kinases, involved in DNA replication and genotoxic stress responses. (PubMed id 12154088) 1 , 2 , 9 Noguchi K.... Uehara Y. (2002) NEK11 regulates CDC25A degradation and the IR-induced G2/M checkpoint. (PubMed id 19734889) 1 , 2 , 9 Melixetian M....Helin K. (2009) NEK11: linking CHK1 and CDC25A in DNA damage checkpoi nt signaling. (PubMed id 20090422) 1 , 2 SA...Helin K. (2010) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 Gerhard D.S....Malek J. (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 Ota T.... Sugano S. (2004) Nucleolar Nek11 is a novel target of Nek2A in G1/S-arrested cells. (PubMed id 15161910) 1 , 2 Noguchi K.... Uehara Y. (2004) Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049) 1 OlA!h J....OvA!di J. (2011) Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614) 1 Rose J.E....Uhl G.R. (2010) Molecular genetics of successful smoking cessation: convergent genome-wide association study results. (PubMed id 18519826) 1 Uhl G.R....Lerman C. (2008) Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348) 1 Barbe L....Andersson-Svahn H. (2008)
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External Searches for NEK11 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing NEK11 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing NEK11 gene
(According to HUGE )
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Specialized Databases showing NEK11 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for NEK11 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for NEK11 gene: Search GeneIP for patents involving NEK11 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor NEK11 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
OriGene Antibodies for NEK11 OriGene shRNA RFP for NEK11 OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for NEK11 OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for NEK11 OriGene Protein Over-expression Lysate for NEK11 Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for NEK11 OriGene 3'-UTR Clone for NEK11 OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for NEK11 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for NEK11 Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs OriGene Purified Protein for NEK11 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for NEK11 OriGene Custom Protein Services for NEK11 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NEK11 QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing NEK11 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat NEK11 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat NEK11 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat NEK11 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat NEK11
Search Tocris compounds for NEK11
NEK11 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NEK11
ThermoFisher Antibodies for NEK11
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat NEK11
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