Aliases for NECAP1 Gene
External Ids for NECAP1 Gene
Previous GeneCards Identifiers for NECAP1 Gene
This gene encodes a protein containing two characteristic WXXF motifs. The encoded protein localizes to clathrin-coated vesicles, where it binds components of the adapter protein complexes and aids in endocytosis. Loss of function of this gene results in early infantile epileptic encephalopathy-21. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
GeneCards Summary for NECAP1 Gene
NECAP1 (NECAP Endocytosis Associated 1) is a Protein Coding gene. Diseases associated with NECAP1 include epileptic encephalopathy, early infantile, 21 and ohtahara syndrome. Among its related pathways are Clathrin derived vesicle budding and Clathrin derived vesicle budding. An important paralog of this gene is NECAP2.
UniProtKB/Swiss-Prot for NECAP1 Gene
Involved in endocytosis.