Aliases for NECAP1 Gene
Aliases for NECAP1 Gene
External Ids for NECAP1 Gene
- HGNC: 24539
- Entrez Gene: 25977
- Ensembl: ENSG00000089818
- OMIM: 611623
- UniProtKB: Q8NC96
Previous GeneCards Identifiers for NECAP1 Gene
- GC12P008110
- GC12P007758
- GC12P007989
- GC12P008234
- GC12P008046
- GC12P007926
Summaries for NECAP1 Gene
-
This gene encodes a protein containing two characteristic WXXF motifs. The encoded protein localizes to clathrin-coated vesicles, where it binds components of the adapter protein complexes and aids in endocytosis. Loss of function of this gene results in early infantile epileptic encephalopathy-21. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
GeneCards Summary for NECAP1 Gene
NECAP1 (NECAP Endocytosis Associated 1) is a Protein Coding gene. Diseases associated with NECAP1 include Epileptic Encephalopathy, Early Infantile, 21 and Undetermined Early-Onset Epileptic Encephalopathy. Among its related pathways are Vesicle-mediated transport and Clathrin derived vesicle budding. An important paralog of this gene is NECAP2.
UniProtKB/Swiss-Prot for NECAP1 Gene
-
Involved in endocytosis.
No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NECAP1 Gene
Genomics for NECAP1 Gene
Regulatory Elements for NECAP1 Gene
Enhancers for NECAP1 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH12F008108 | 1 | Ensembl ENCODE | 46.8 | +26.8 | 26806 | 0.4 | BCOR CTCF TEAD4 MAX ZNF384 ZIC2 ZNF2 RAD21 RFX5 TEAD3 | NECAP1 GC12P008103 CLEC4A |
| GH12F008096 | 0.4 | Ensembl | 49.4 | +14.4 | 14390 | 0.8 | OSR2 | NECAP1 CLEC4A FOXJ2 GC12P008091 GC12P008103 |
| GH12F007968 | 1.7 | FANTOM5 Ensembl ENCODE | 11 | -111.0 | -111011 | 4.8 | HDGF ATF1 PKNOX1 CREB3L1 SIN3A FEZF1 GLI4 ETS1 ZNF121 GLIS2 | SLC2A3 NECAP1 CLEC4A SLC2A14 FOXJ2 CLEC6A C3AR1 GC12P007976 |
| GH12F007958 | 1.6 | FANTOM5 Ensembl ENCODE | 7.7 | -121.4 | -121411 | 5.6 | PKNOX1 ATF1 WRNIP1 ARID4B SIN3A ZNF2 GATA2 SP3 SP5 NCOA1 | SLC2A3 HADHAP2 NECAP1 CLEC4A FOXJ2 GC12P007976 |
| GH12F008087 | 0.9 | Ensembl ENCODE | 12.8 | +6.2 | 6170 | 2.1 | TBP PKNOX1 MXI1 WRNIP1 MAX EBF1 TBX21 ZNF623 IKZF1 ZNF143 | NECAP1 C3AR1 CLEC4A FOXJ2 GC12P008091 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around NECAP1 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for NECAP1 Gene
- Chromosome:
- 12
- Start:
- 8,082,211 bp from pter
- End:
- 8,097,777 bp from pter
- Size:
- 15,567 bases
- Orientation:
- Plus strand
Genomic View for NECAP1 Gene
Genes around NECAP1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12p13.31 by Ensembl
- 12p13.31 by Entrez Gene
- 12p13.31 by HGNC
NECAP1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for NECAP1 Gene
Proteins for NECAP1 Gene
-
Protein details for NECAP1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8NC96-NECP1_HUMAN
- Recommended name:
- Adaptin ear-binding coat-associated protein 1
- Protein Accession:
- Q8NC96
- Q2NL73
- Q5XG95
- Q6NWY6
- Q8N153
- Q8NCB0
- Q9BU52
- Q9Y407
Protein attributes for NECAP1 Gene
- Size:
- 275 amino acids
- Molecular mass:
- 29737 Da
- Quaternary structure:
-
- Interacts with AP1G1 and AP2A1 components of the adapter protein complexes AP-1 and AP-2. Interacts with the GAE domain proteins GGA1, GGA2 and GGA3 (By similarity).
- SequenceCaution:
-
- Sequence=AAH02888.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Protein Expression for NECAP1 Gene
Post-translational modifications for NECAP1 Gene
Other Protein References for NECAP1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for NECAP1
- Novus Biologicals Antibodies for NECAP1
- Invitrogen Antibodies for NECAP1
- antibodies-online Antibodies for NECAP1: See all 9
- Search GeneTex for Antibodies for NECAP1
Protein Products
-
OriGene Purified Proteins for NECAP1
- Search Origene for MassSpec and Protein Over-expression Lysates for NECAP1
- Origene Custom Protein Services for NECAP1
- antibodies-online Proteins for NECAP1: See all 7
- Search antibodies-online for peptides
- Search GeneTex for Proteins for NECAP1
Assay Products
- antibodies-online Kits for NECAP1: See all 4
No data available for DME Specific Peptides for NECAP1 Gene
Domains & Families for NECAP1 Gene
Protein Domains for NECAP1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for NECAP1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q8NC96UniProtKB/Swiss-Prot:
NECP1_HUMAN :- The WXXF motifs mediate binding of accessory proteins to the ear-domain of AP-1, GGAs and AP-2 through hydrophobic interactions. Selective binding to the GAE domains of AP-1 or to the alpha-ear domain of AP-2 is tuned by the acidic context surrounding the motif and the properties of the second residue of the motif itself. The WXXF motif 1, which is preceded by an acidic residue and has a glycine in second position mediates specific interaction with AP-1. The WXXF motif 2, which is followed by the C-terminal carboxyl group negative charge, allows specific interaction with AP-2 (By similarity).
- Belongs to the NECAP family.
- Domain:
-
- The WXXF motifs mediate binding of accessory proteins to the ear-domain of AP-1, GGAs and AP-2 through hydrophobic interactions. Selective binding to the GAE domains of AP-1 or to the alpha-ear domain of AP-2 is tuned by the acidic context surrounding the motif and the properties of the second residue of the motif itself. The WXXF motif 1, which is preceded by an acidic residue and has a glycine in second position mediates specific interaction with AP-1. The WXXF motif 2, which is followed by the C-terminal carboxyl group negative charge, allows specific interaction with AP-2 (By similarity).
- Family:
-
- Belongs to the NECAP family.
No data available for Gene Families for NECAP1 Gene
Function for NECAP1 Gene
Molecular function for NECAP1 Gene
- UniProtKB/Swiss-Prot Function:
- Involved in endocytosis.
Phenotypes for NECAP1 Gene
- GenomeRNAi human phenotypes for NECAP1:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for NECAP1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for NECAP1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for NECAP1 gene
- Search ViGene Biosciences for NECAP1
CRISPR Products
-
OriGene CRISPR knockouts for NECAP1
- GenScript: Design CRISPR guide RNA sequences for NECAP1
miRNA for NECAP1 Gene
- miRTarBase miRNAs that target NECAP1
-
- hsa-mir-1254 (MIRT035856)
- hsa-mir-423-5p (MIRT038063)
- hsa-mir-1207-5p (MIRT067285)
- hsa-mir-2054 (MIRT067286)
- hsa-mir-4310 (MIRT067288)
- hsa-mir-4763-3p (MIRT067290)
- hsa-mir-5197-5p (MIRT067293)
- hsa-mir-6132 (MIRT067294)
- hsa-mir-6836-5p (MIRT067296)
- hsa-mir-7150 (MIRT067298)
- hsa-mir-7157-5p (MIRT067299)
- hsa-mir-32-5p (MIRT136291)
- hsa-mir-92a-3p (MIRT136292)
- hsa-mir-335-3p (MIRT136300)
- hsa-mir-92b-3p (MIRT136301)
- hsa-mir-5096 (MIRT485309)
- hsa-mir-513a-5p (MIRT485310)
- hsa-mir-4736 (MIRT485311)
- hsa-mir-27b-3p (MIRT485312)
- hsa-mir-27a-3p (MIRT485313)
miRNA Products
- Search ViGene Biosciences for NECAP1
Clone Products
- Sino Biological Human cDNA Clone for NECAP1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for NECAP1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NECAP1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for NECAP1
-
ViGene Biosciences adenoviral particle packaged cDNA for NECAP1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for NECAP1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for NECAP1 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for NECAP1 Gene
Localization for NECAP1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for NECAP1 Gene
- Cytoplasmic vesicle, clathrin-coated vesicle membrane. Cell membrane. Note=Colocalizes with AP-2 at the plasma membrane. {ECO:0000250}.
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| plasma membrane | 3 |
| cytoskeleton | 2 |
| extracellular | 1 |
| nucleus | 1 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | IEA | -- |
| GO:0005905 | clathrin-coated pit | IEA | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0030125 | clathrin vesicle coat | IEA | -- |
| GO:0030665 | clathrin-coated vesicle membrane | IEA | -- |
Pathways & Interactions for NECAP1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Clathrin derived vesicle budding | ||
| 2 | Clathrin-mediated endocytosis | ||
| 3 | Vesicle-mediated transport | ||
Pathways by source for NECAP1 Gene
Interacting Proteins for NECAP1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006810 | transport | IEA | -- |
| GO:0006897 | endocytosis | IEA | -- |
| GO:0015031 | protein transport | IEA | -- |
No data available for SIGNOR curated interactions for NECAP1 Gene
Transcripts for NECAP1 Gene
mRNA/cDNA for NECAP1 Gene
- (1) REFSEQ mRNAs :
- (13) Additional mRNA sequences :
- (237) Selected AceView cDNA sequences:
- (9) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for NECAP1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for NECAP1
- GenScript: Design CRISPR guide RNA sequences for NECAP1
miRNA Products
- Search ViGene Biosciences for NECAP1
Clone Products
- Sino Biological Human cDNA Clone for NECAP1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for NECAP1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NECAP1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | |||||||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||
| SP4: | - | - | |||||||||||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||||||||||||
| SP6: |
Expression for NECAP1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Hematopoietic System)
- Granulocytes Peripheral Blood
-
Brain (Nervous System)
This gene is overexpressed in Brain (33.5), Fetal Brain (8.9), and Breast (8.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for NECAP1 Gene
NURSA nuclear receptor signaling pathways regulating expression of NECAP1 Gene:
NECAP1SOURCE GeneReport for Unigene cluster for NECAP1 Gene:
Hs.555927Primer Products
-
OriGene qPCR primer pairs and template standards for NECAP1
-
OriGene qPCR primer pairs for NECAP1
No data available for mRNA differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for NECAP1 Gene
Orthologs for NECAP1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | NECAP1 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | NECAP1 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | NECAP1 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Necap1 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Necap1 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | NECAP1 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | NECAP1 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | NECAP1 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | Str.17597 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | necap1 34 35 |
|
||
| zgc73124 34 |
|
||||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP000322 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG9132 34 35 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | Y110A2AR.3 35 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.2050 35 |
|
OneToMany |
- Species where no ortholog for NECAP1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for NECAP1 Gene
(1) SIMAP similar genes for NECAP1 Gene using alignment to 4 proteins:
Pseudogenes.org Pseudogenes for NECAP1 Gene
Variants for NECAP1 Gene
| SNP ID | Clin | Chr 12 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs587777420 | other | 8,089,982(+) | GCCTC(C/T)GAATC | nc-transcript-variant, reference, stop-gained | |
| rs1004824 | -- | 8,085,539(-) | CATGT(A/G)CTGTA | intron-variant | |
| rs10492105 | -- | 8,084,991(+) | GATAC(A/T)TATTG | intron-variant | |
| rs10492106 | -- | 8,093,806(+) | GAGGG(A/T)TAAAT | intron-variant | |
| rs1062836 | -- | 8,096,454(+) | ATCAT(C/G)TCATG | nc-transcript-variant, utr-variant-3-prime |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2759877 | CNV | gain+loss | 17122850 |
| nsv1045521 | CNV | gain | 25217958 |
| nsv428270 | CNV | gain | 18775914 |
| nsv475738 | CNV | novel sequence insertion | 20440878 |
Residual Variation Intolerance Score:
39.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.44;
28.22% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for NECAP1 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NECAP1 Gene
Disorders for NECAP1 Gene
(4) MalaCards diseases for NECAP1 Gene - From: OMIM, ClinVar, GeneTests, Orphanet, DISEASES, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| epileptic encephalopathy, early infantile, 21 |
|
|
| undetermined early-onset epileptic encephalopathy |
|
|
| infantile epileptic encephalopathy |
|
|
| hypertonia |
|
|
Search NECAP1 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
NECP1_HUMAN- Epileptic encephalopathy, early infantile, 21 (EIEE21) [MIM:615833]: A severe disease characterized by intractable seizures, profound global developmental delay, and persistent severe axial hypotonia as well as appendicular hypertonia. {ECO:0000269 PubMed:24399846}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Relevant External Links for NECAP1
No data available for Genatlas for NECAP1 Gene
Publications for NECAP1 Gene
- NECAP1 loss of function leads to a severe infantile epileptic encephalopathy. (PMID: 24399846) Alazami A.M. … Alkuraya F.S. (J. Med. Genet. 2014) 3 4 64
- Characterization of the localization and function of NECAP 1 in neurons. (PMID: 16879712) Murshid A. … Presley J.F. (J. Neurochem. 2006) 3 22 64
- Molecular mechanisms in clathrin-mediated membrane budding revealed through subcellular proteomics. (PMID: 15494011) Ritter B. … McPherson P.S. (Biochem. Soc. Trans. 2004) 2 3 64
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
Products for NECAP1 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for NECAP1
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for NECAP1
- Search Origene for MassSpec and Protein Over-expression Lysates for NECAP1
- Origene Custom Protein Services for NECAP1
- Origene mouse_rna, siRNA, rat_shrna, shRNA, and RNAi products in human, mouse, rat for NECAP1
- Browse OriGene Inhibitory RNA Products For NECAP1
- OriGene qPCR primer pairs and template standards for NECAP1
- OriGene qPCR primer pairs for NECAP1
- OriGene CRISPR knockouts for NECAP1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For NECAP1
- GenScript: Next-day shipping cDNA clones in your preferred vector
- GenScript Custom Purified and Recombinant Proteins Services for NECAP1
- GenScript Custom Assay Services for NECAP1
- GenScript Custom overexpressing Cell Line Services for NECAP1
- GenScript: Design CRISPR guide RNA sequences for NECAP1
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for NECAP1
- Sino Biological Human cDNA Clone for NECAP1
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for NECAP1
- Novus Biologicals proteins and lysates for NECAP1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- antibodies-online Antibodies for NECAP1: See all 9
- antibodies-online Kits for NECAP1: See all 4
- antibodies-online Proteins for NECAP1: See all 7
- Search antibodies-online for peptides
- Search GeneTex for Antibodies for NECAP1
- Search GeneTex for Proteins for NECAP1
- ViGene Biosciences adenoviral particle packaged cDNA for NECAP1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for NECAP1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for NECAP1 gene
- Search ViGene Biosciences for NECAP1
- Horizon Cell Lines for NECAP1
- Cyagen custom Knockout/knockin (KOKI) mouse models for NECAP1
- VectorBuilder custom plasmid, inducible vectors for NECAP1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NECAP1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for NECAP1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab