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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NDUFV3 Gene

protein-coding   GIFtS: 60
GCID: GC21P044299

NADH Dehydrogenase (Ubiquinone) Flavoprotein 3, 10kDa

(Previous name: NADH dehydrogenase (ubiquinone) flavoprotein 3 (10kD))
Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, 15RNAdb, and/or 11Nature:405,311-319 and CroW21)
About This Section

Aliases
NADH Dehydrogenase (Ubiquinone) Flavoprotein 3, 10kDa1 2     CI-9KD2
Complex I 10kDa Subunit1 2     Complex I, Mitochondrial Respiratory Chain, 10-KD Subunit2
Complex I-9kD2 3     Mitochondrial NADH Oxidoreductase-Like Protein2
Renal Carcinoma Antigen NY-REN-42 3     NADH Dehydrogenase [Ubiquinone] Flavoprotein 3, Mitochondrial2
NADH-Ubiquinone Oxidoreductase 9 KDa Subunit2 3     NADH-Ubiquinone Oxidoreductase 9 KD Subunit2
NADH Dehydrogenase (Ubiquinone) Flavoprotein 3 (10kD)1     NADH-Ubiquinone Oxidoreductase Flavoprotein 3, 10kD2
NADH-Ubiquinone Oxidoreductase 9 KD Subunit Precursor, EC 1.6.5.311     CI-9kD3
CI-10k2     

External Ids:    HGNC: 77191   Entrez Gene: 47312   Ensembl: ENSG000001601947   OMIM: 6021845   UniProtKB: P561813   

Export aliases for NDUFV3 gene to outside databases

Previous GC identifers: GC21P040847 GC21P043194 GC21P043193 GC21P043172


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NDUFV3 Gene:
The protein encoded by this gene is one of at least forty-one subunits that make up the NADH-ubiquinone
oxidoreductase complex. This complex is part of the mitochondrial respiratory chain and serves to catalyze the
rotenone-sensitive oxidation of NADH and the reduction of ubiquinone. The encoded protein is one of three
proteins found in the flavoprotein fraction of the complex. The specific function of the encoded protein is
unknown. Two transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq,
Jul 2008)

GeneCards Summary for NDUFV3 Gene: 
NDUFV3 (NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa) is a protein-coding gene. Diseases associated with NDUFV3 include autosomal recessive nonsyndromic deafness, and nonsyndromic deafness, and among its related super-pathways are Electron Transport Chain and Metabolic pathways. GO annotations related to this gene include NADH dehydrogenase (ubiquinone) activity.

UniProtKB/Swiss-Prot: NDUV3_HUMAN, P56181
Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that
is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the
respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Gene Wiki entry for NDUFV3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics, Whole Chromsome Sequence According to Nature (Cited Here with Permission):405,311-319 and CroW21)
About This Section
RefSeq DNA sequence:
NC_000021.8  NC_018932.2  NT_011515.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NDUFV3 gene promoter:
         ATF-2   E47   HEN1   PPAR-gamma1   POU2F1   POU2F1a   Hand1   PPAR-gamma2   c-Jun   Zic3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNDUFV3 promoter sequence

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Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NDUFV3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 21q22.3   Ensembl cytogenetic band:  21q22.3   HGNC cytogenetic band: 21q22.3
Nature(405: 311-319) cytogenetic band:   21q22.3
NDUFV3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NDUFV3 gene location
GeneLoc information about chromosome 21         GeneLoc Exon Structure

(about GC identifiers)
GC21P044299:   GeneLoc Nature:405,311-319
Start:
44,299,754 bp from pter       29,860,728 bp from centromere
End:
44,329,783 bp from pter 29,876,602 bp from centromere
Size:
30,030 bases 15,875 bases
Orientation:
plus strand plus strand

Whole chromosome sequencing:
cDNA sequence: X99726X99727X99728
genomic clones: KB1405B7


(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NDUV3_HUMAN, P56181 (See protein sequence)
Recommended Name: NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial precursor  
Size: 108 amino acids; 11941 Da
Subunit: Complex I is composed of 45 different subunits. This is a component of the flavoprotein-sulfur (FP)
fragment of the enzyme
Subcellular location: Mitochondrion inner membrane; Peripheral membrane protein; Matrix side
Secondary accessions: A8K0M1 J3KNX7 Q6FGD3 Q8WU60 Q9HCR5
Alternative splicing: 2 isoforms:  P56181-1   P56181-2   (Ref.7 (AAH21217) sequence is in conflict in position: 415:D->N. Contains a phosphoserine at position 164. Contains a phosphoserine at position 160. Contains a phosphoserine at position 162)

Explore the universe of human proteins at neXtProt for NDUFV3: NX_P56181

Explore proteomics data for NDUFV3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P56181

  • NDUFV3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NDUFV3 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001001503.1  NP_066553.3  

    ENSEMBL proteins: 
     ENSP00000346196   ENSP00000342895  
    Reactome Protein details: P56181
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    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005739mitochondrion IDA--
    GO:0005743mitochondrial inner membrane TAS--
    GO:0005747mitochondrial respiratory chain complex I NAS9878551

    NDUFV3 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    comI: Mitochondrial respiratory chain complex / Complex I

    1 InterPro protein domain:
     IPR026193 NDUFV3

    Graphical View of Domain Structure for InterPro Entry P56181

    ProtoNet protein and cluster: P56181

    UniProtKB/Swiss-Prot: NDUV3_HUMAN, P56181
    Similarity: Belongs to the complex I NDUFV3 subunit family


    NDUFV3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NDUV3_HUMAN, P56181
    Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that
    is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the
    respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

         Genatlas biochemistry entry for NDUFV3:
    NADH ubiquinone dehydrogenase (Q reductase),component of the complex I multi-subunit of the phosphorylation
    (OXPHOS),flavoprotein 3,inner mitochondrial membrane,ubiquitously expressed

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008137NADH dehydrogenase (ubiquinone) activity NAS9878551
         
    NDUFV3 for ontologies           About GeneDecksing


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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for NDUFV3 About                                                                                                See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.0.81
    Parkinson's disease0.61
    Respiratory electron transport0.81
    Oxidative phosphorylation0.51
    Electron Transport Chain0.75
    Huntington's disease0.47
    The citric acid (TCA) cycle and respiratory electron transport0.72
    Alzheimer's disease0.46
    2Metabolism
    Metabolism0.40
    Metabolic pathways0.40
    3FOXA1 transcription factor network
    FOXA1 transcription factor network

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    3 BioSystems Pathways for NDUFV3
        Electron Transport Chain
    Oxidative phosphorylation
    FOXA1 transcription factor network

    4        Reactome Pathways for NDUFV3
        Respiratory electron transport
    Metabolism
    Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    The citric acid (TCA) cycle and respiratory electron transport


    5/6         Kegg Pathways  (Kegg details for NDUFV3) (see all 6):
        Oxidative phosphorylation
    Metabolic pathways
    Non-alcoholic fatty liver disease (NAFLD)
    Alzheimer's disease
    Parkinson's disease


    NDUFV3 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NDUFV3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/58 Interacting proteins for NDUFV3 (P561813 ENSP000003461964) via UniProtKB, MINT, STRING, and/or I2D (see all 58)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NDUFA2O436783, ENSP000002521024I2D: score=1 STRING: ENSP00000252102
    PHYHIPQ925613, ENSP000003200174I2D: score=4 STRING: ENSP00000320017
    NDUFC1ENSP000003777704STRING: ENSP00000377770 STRING: ENSP00000265500
    CYC1ENSP000003171594STRING: ENSP00000317159
    ENSG00000267059ENSP000002629464STRING: ENSP00000262946
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006120mitochondrial electron transport, NADH to ubiquinone NAS9878551
    GO:0022904respiratory electron transport chain TAS--
    GO:0044237cellular metabolic process TAS--
    GO:0044281small molecule metabolic process TAS--

    NDUFV3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for NDUFV3 (NDUV3)

    8 HMDB Compounds for NDUFV3    About this table
    CompoundSynonyms CAS #PubMed Ids
    FAD1H-Purin-6-amine flavin dinucleotide (see all 21)146-14-5--
    IronArmco iron (see all 19)7439-89-6--
    NAD3-Carbamoyl-1-D-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate (see all 28)53-84-9--
    NADH1,4-Dihydronicotinamide adenine dinucleotide (see all 17)58-68-4--
    QH2CoQH2 (see all 5)56275-39-9--
    SulfideSulfide (see all 4)18496-25-8--
    Ubiquinone Q1Coenzyme Q (see all 9)727-81-1--
    Ubiquinone Q22-(3,7-dimethyl-2,6-octadienyl)-5,6-dimethoxy-3-methyl-2,5-Cyclohexadiene-1,4-dione (see all 7)606-06-4--

    1 DrugBank Compound for NDUFV3    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    NADHbeta-DPNH (see all 18)606-68-8target--17139284 17016423

    Search CenterWatch for drugs/clinical trials and news about NDUFV3 / NDUV3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NDUFV3 gene (2 alternative transcripts): 
    NM_001001503.1  NM_021075.3  

    Unigene Cluster for NDUFV3:

    NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa
    Hs.473937  [show with all ESTs]
    Unigene Representative Sequence: NM_021075
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000460259 ENST00000354250(uc002zcm.3) ENST00000340344(uc002zcn.3)
    ENST00000460740

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    Additional mRNA sequence: 

    AK056041.1 AK289586.1 AK308228.1 AY173949.1 BC021217.2 BC033766.1 BC054016.1 CR542174.1 
    CR542190.1 

    10 DOTS entries:

    DT.97759871  DT.100036648  DT.75103547  DT.95363881  DT.91831138  DT.121139842  DT.100036649  DT.101960934 
    DT.100700376  DT.75106687 

    24/212 AceView cDNA sequences (see all 212):

    BM683940 BF765237 BI829092 CR607646 BI908255 BM905262 NM_021075 NM_001001503 
    AI570479 AI609645 AW137829 CR593887 BE465439 BU741849 BM471674 BP336670 
    AA478027 BU621933 BQ001645 CF140521 F32007 CR616335 CB113244 AA371023 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for NDUFV3 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6
    SP1:                          -                 -         
    SP2:                          -     -     -     -         
    SP3:                                                      
    SP4:                    -     -                           
    SP5:                    -     -     -     -     -         


    ECgene alternative splicing isoforms for NDUFV3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NDUFV3 expression in normal human tissues (normalized intensities)      NDUFV3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACTACAGCAC
    NDUFV3 Expression
    About this image


    NDUFV3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/41 selected tissues (see all 41) fully expand
     
     Brain (Nervous System)    fully expand to see all 8 entries
             Cerebral Cortex
             brain/midbrain   
     
     Epithelium
             vagina ; squamous epithelial cells   
     
     Uterus
             uterus, post-menopause ; glandular cells   
     
     Colon (Gastrointestinal Tract)    fully expand to see all 4 entries
             colon ; peripheral nerve/ganglion   
     
     Testis (Reproductive System)    fully expand to see all 3 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   

    See NDUFV3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NDUFV3

    SOURCE GeneReport for Unigene cluster: Hs.473937
        SABiosciences Expression via Pathway-Focused PCR Array including NDUFV3: 
              Mitochondrial Energy Metabolism in human mouse rat

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for NDUFV3 gene from 2/8 species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ndufv31 , 5 NADH dehydrogenase (ubiquinone) flavoprotein 31, 5 66.74(n)1
    52.93(a)1
      17 (16.64 cM)5
    783301  NM_030087.21  NP_084363.21 
     315201155 
    zebrafish
    (Danio rerio)
    Actinopterygii wufl83h062 wufl83h06 81.34(n)   334568  BI878863.1 


    ENSEMBL Gene Tree for NDUFV3 (if available)
    TreeFam Gene Tree for NDUFV3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/628 SNPs in NDUFV3 are shown (see all 628)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 21 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1923808621,2
    --44311381(+) AAGCCA/GAGATT 2 -- us2k10--------
    rs1850017301,2
    --44311410(+) TCTAGC/GCTGGG 2 -- us2k10--------
    rs1140286031,2
    F--44311508(+) CTGGCC/TGGTGA 2 -- us2k11Minor allele frequency- T:0.02WA 118
    rs130477791,2
    C,F--44311517(+) GACCAT/CGCCAG 2 -- us2k112Minor allele frequency- C:0.41NA WA CSA EA 385
    rs1866629891,2
    --44311561(+) TTGCAA/GCTCCA 2 -- us2k10--------
    rs1913652501,2
    --44311596(+) GTGCCC/TGCTGG 2 -- us2k10--------
    rs794451611,2
    --44311632(+) AGGTCC/GATGAA 2 -- us2k10--------
    rs1895691941,2
    --44311672(+) ATCAGG/TATCCC 2 -- us2k10--------
    rs130512881,2
    C,F--44311717(+) ACCTCC/ACAAAG 2 -- us2k13Minor allele frequency- A:0.33NA WA 6
    rs130508781,2
    C,F--44311718(+) CCTCAT/CAAAGG 2 -- us2k13Minor allele frequency- C:0.33NA WA 6

    HapMap Linkage Disequilibrium report for NDUFV3 (44299754 - 44329783 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for NDUFV3:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2666871CNV Deletion23128226
    esv1340851CNV Insertion17803354
    esv2652948CNV Insertion19546169
    nsv187067CNV Insertion16902084
    esv1737156CNV Insertion17803354
    nsv834105CNV Loss17160897
    nsv913812CNV Gain21882294
    nsv913820CNV Gain21882294


    Human Gene Mutation Database (HGMD): NDUFV3
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing NDUFV3
    DNA2.0 Custom Variant and Variant Library Synthesis for NDUFV3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 602184    OMIM disorders: --

    8 diseases for NDUFV3:    About MalaCards
    autosomal recessive nonsyndromic deafness    nonsyndromic deafness    huntington's disease    down syndrome
    renal cell carcinoma    parkinson's disease    alzheimer's disease    prostatitis

    1 disease from the University of Copenhagen DISEASES database for NDUFV3:
    Down syndrome

    NDUFV3 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): NDUFV3
    Human Genome Epidemiology (HuGE) Navigator: NDUFV3 (5 documents)

    Export disorders for NDUFV3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NDUFV3 gene, integrated from 9 sources (see all 29):
    (articles sorted by number of sources associating them with NDUFV3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and characterization of the human mitochondrial NADH:oxidoreductase 10-kDa gene (NDUFV3). (PubMed id 9344673)1, 2, 3, 9 de Coo R.F.M.... van Oost B.A. (1997)
    2. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    3. Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. (PubMed id 19343046)1, 4 Saito A....Kamatani N. (2009)
    4. Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey. (PubMed id 18977241)1, 4 Starr J.M....Deary I.J. (2008)
    5. Polymorphisms in mitochondrial genes and prostate can cer risk. (PubMed id 19064571)1, 4 Wang L....Thibodeau S.N. (2008)
    6. A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition. (PubMed id 17601350)1, 4 Harris S.E....Deary I.J. (2007)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    9. The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification. (PubMed id 12611891)1, 2 Murray J.... Capaldi R.A. (2003)
    10. The DNA sequence of human chromosome 21. (PubMed id 10830953)1, 2 Hattori M....Yaspo M.L. (2000)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 4731 HGNC: 7719 AceView: NDUFV3 Ensembl:ENSG00000160194 euGenes: HUgn4731
    ECgene: NDUFV3 Kegg: 4731 H-InvDB: NDUFV3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NDUFV3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NDUFV3 gene:
    Search GeneIP for patents involving NDUFV3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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