NDUFV2 Gene
protein-coding GIFtS: 63
GCID: GC18P009092
|
|
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa(Previous name: NADH dehydrogenase (ubiquinone) flavoprotein 2 (24kD) )
| |
Aliases
for NDUFV2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| NADH Dehydrogenase (Ubiquinone) Flavoprotein 2, 24kDa1 2 | | NADH Dehydrogenase [Ubiquinone] Flavoprotein 2, Mitochondrial2 | | CI-24k1 2 | | NADH Dehydrogenase Ubiquinone Flavoprotein 2, Mitochondrial2 | | NADH-Ubiquinone Oxidoreductase 24 KDa Subunit2 3 | | NADH-Ubiquinone Oxidoreductase Flavoprotein 22 | | NADH Dehydrogenase (Ubiquinone) Flavoprotein 2 (24kD)1 | | Nuclear-Encoded Mitochondrial NADH-Ubiquinone Reductase 24Kd Subunit2 | | Complex I 24kDa Subunit2 | | EC 1.6.5.33 | | Complex I, Mitochondrial Respitory Chain, 24 KD Subunit2 | | EC 1.6.99.33 |
Export aliases for NDUFV2 gene to outside databasesPrevious GC identifers: GC19M054373 GC18P009159 |
Summaries
for NDUFV2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for NDUFV2:
The NADH-ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory chain catalyzes the transfer ofelectrons from NADH to ubiquinone, and consists of at least 43 subunits. The complex is located in the innermitochondrial membrane. This gene encodes the 24 kDa subunit of complex I, and is involved in electron transfer.Mutations in this gene are implicated in Parkinson's disease, bipolar disorder, schizophrenia, and have been found inone case of early onset hypertrophic cardiomyopathy and encephalopathy. A non-transcribed pseudogene of this locus isfound on chromosome 19. (provided by RefSeq, Oct 2009)
UniProtKB/Swiss-Prot: NDUV2_HUMAN, P19404Function: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believedto belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADHto the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)
Gene Wiki entry for NDUFV2
|
Genomic Views
for NDUFV2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000018.9 NC_018929.1 NT_010859.14
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the NDUFV2 gene promoter:
Oct-B1 POU2F2 (Oct-2.1) oct-B2 oct-B3 p53 POU2F2 POU2F2C POU2F1 POU2F1a POU2F2B
Other transcription factors
Search SABiosciences Chromatin IP Primers for NDUFV2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NDUFV2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 18p11.22 Ensembl cytogenetic band: 18p11.22 HGNC cytogenetic band: 18p11.22NDUFV2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 18 GeneLoc Exon Structure GeneLoc location for GC18P009092: view genomic region
(about GC identifiers)
Start:
|
9,102,628 bp from pter |
End:
|
9,134,343 bp from pter |
Size:
|
31,716 bases |
Orientation:
|
plus strand |
|
Proteins
for NDUFV2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NDUV2_HUMAN, P19404 (See
protein sequence)Recommended Name: NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial precursor Size: 249 amino acids; 27392 Da
Cofactor: Binds 1 2Fe-2S cluster (Potential)
Subunit: Complex I is composed of 45 different subunits. This is a component of the flavoprotein-sulfur (FP) fragmentof the enzyme
Subcellular location: Mitochondrion inner membrane
Secondary accessions: Q9BV41Explore the universe of human proteins at neXtProt for NDUFV2: NX_P19404
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P19404
NDUFV2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_066552.2
ENSEMBL proteins: ENSP00000461911 ENSP00000327268 ENSP00000464504 ENSP00000382908 Reactome Protein details: P19404
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
NDUFV2 for ontologies About GeneDecksing
NDUFV2 Antibody Products:
Assay Products for NDUFV2: |
Protein
Domains /
Families
for NDUFV2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NDUFV2 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P19404ProtoNet protein and cluster: P19404 1 Blocks protein family: IPB002023 NADH dehydrogenase (ubiquinone)
UniProtKB/Swiss-Prot: NDUV2_HUMAN, P19404Similarity: Belongs to the complex I 24 kDa subunit family |
Function
for NDUFV2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: NDUV2_HUMAN, P19404Function: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believedto belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADHto the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)Catalytic activity: NADH + ubiquinone = NAD(+) + ubiquinolCatalytic activity: NADH + acceptor = NAD(+) + reduced acceptor Genatlas biochemistry entry for NDUFV2:NADH ubiquinone dehydrogenase (Q reductase),component of the complex I multi-subunit enzyme of the oxidativephosphorylation (OXPHOS),flavoprotein 2,inner mitochondrial membrane,involved in the susceptibility to Parkinsondisease
Enzyme Numbers (IUBMB): EC 1.6.99.31 EC 1.6.5.31
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NDUFV2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NDUFV2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: NDUFV2 (NM_021074) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NDUFV2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NDUFV2 |
Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table
NDUFV2 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for NDUFV2:
Animal Models:
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Ndufv2):
NDUFV2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for NDUFV2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | | | 2 | Metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2  BioSystems Pathways for NDUFV2
4 
Reactome Pathways for NDUFV2
5 
Kegg Pathways (Kegg details for NDUFV2):
NDUFV2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NDUFV2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/54 Interacting proteins for NDUFV2 (P194042, 3 ENSP000003272684) via UniProtKB, MINT, STRING, and/or I2D (see all 54)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
NDUFV2 for ontologies About GeneDecksing
|
Drugs & Compounds
for NDUFV2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for NDUFV2
8 HMDB Compounds for NDUFV2 About this table
1 DrugBank Compound for NDUFV2 About this table
Search CenterWatch for drugs/clinical trials and news about NDUFV2 / NDUV2
|
Transcripts
for NDUFV2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for NDUFV2 gene: NM_021074.4 Unigene Cluster for NDUFV2: NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa Hs.464572 [show with all ESTs]Unigene Representative Sequence: BM9133849 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000577703 ENST00000318388(uc002knu.3) ENST00000497577 ENST00000583375
ENST00000400033 ENST00000474350 ENST00000483511 ENST00000465096 ENST00000474740
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NDUFV2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NDUFV2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: NDUFV2 (NM_021074) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NDUFV2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NDUFV2 |
Additional cDNA sequence: AF147367.1 AK291865.1 AK312129.1 BC001632.1 BC017487.1 BC071689.1 CR456928.1 M22538.1 15 DOTS entries: DT.75189311 DT.455777 DT.121462288 DT.86852346 DT.95128794 DT.92441164 DT.70102367 DT.75103998 DT.95111315 DT.100724929 DT.121462126 DT.86852347 DT.86857170 DT.91710486 DT.95260621 24/287 AceView cDNA sequences (see all 287): BX417460 CR595344 BU675606 BG254860 CB218086 BM789853 BI909921 BU552674 BC001632 CR618099 BU737748 T47237 CR594679 BU789002 AA176527 AA176716 BU737701 BM765929 BM995962 N78386 BM700145 AA565016 AA811237 BC017487
GeneLoc Exon Structure
|
Expression
for NDUFV2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NDUFV2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTTCGAAACT
About this image
See NDUFV2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NDUFV2
SOURCE GeneReport for Unigene cluster: Hs.464572
SABiosciences Expression via Pathway-Focused PCR Array including NDUFV2:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NDUFV2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NDUFV2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NDUFV2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NDUFV2 |
Orthologs
for NDUFV2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for NDUFV2 gene from 10/33 species (see all 33) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Ndufv21 , 5 |
NADH dehydrogenase (ubiquinone) flavoprotein 21, 5 |
90.69(n)1
93.52(a)1 |
|
17 (35.26 cM)5
729001 NM_028388.21 NP_082664.11
660787955 |
chicken
(Gallus gallus) |
Aves |
NDUFV21 |
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa |
78.1(n)
85.71(a) |
|
426488 XM_424129.3 XP_424129.3 |
lizard
(Anolis carolinensis) |
Reptilia |
NDUFV26 |
-- |
81(a) |
1 ↔ 1 |
GL343319.1(468920-484975) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.209442 |
Xenopus laevis transcribed sequence with strong similarity more |
91.37(n) |
|
BX847160.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
zgc731982 |
NADH dehydrogenase flavoprotein 2 |
75.5(n) |
|
393720 BC059546.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG57031 , 3 |
NADH dehydrogenase (ubiquinone)3
CG57031 |
72(a)
(best of 2)3
64.04(n)1
71.76(a)1 |
|
16B103
327401 NM_133000.21 NP_573228.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
F53F4.103
CELE_F53F4.101 |
NADH-ubiquinone dehydrogenase 24 KD subunit3
Protein F53F4.101 |
66(a)3
64.89(n)1
66.67(a)1 |
|
V(13627287-13628083)3
1798501 NM_073975.51 NP_506376.11 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT4G025801 |
NADH dehydrogenase (ubiquinone) flavoprotein 2 |
57.17(n)
51.69(a) |
|
828130 NM_116492.3 NP_567244.1 |
rice
(Oryza sativa) |
Liliopsida |
Os.110692 |
Oryza sativa (japonica cultivar-group) cDNA cloneJ more |
71.37(n) |
|
AK061566.1 |
E. coli
(Escherichia coli) |
Gamma proteobacteria |
nuoE6 |
NADH:ubiquinone oxidoreductase, chain E |
34(a) |
1 ↔ 1 |
Chromosome(2399574-2400074) |
ENSEMBL Gene Tree for NDUFV2 (if available)
TreeFam Gene Tree for NDUFV2 (if available) |
Paralogs
for NDUFV2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for NDUFV2 gene
NDUFV2 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for NDUFV2
PGOHUM00000259358 PGOHUM00000260441
|
Genomic Variants
for NDUFV2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 18 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for NDUFV2 (9102628 - 9134343 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for NDUFV2
2 CNVs: 39213 88709
Human Gene Mutation Database (HGMD): NDUFV2
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NDUFV2 |
|
Disorders
/ Diseases
for NDUFV2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NDUFV2 for disorders About GeneDecksing
OMIM gene information: 600532
OMIM disorders: 252010
14  diseases for NDUFV2: About MalaCardshypertrophic cardiomyopathy bipolar disorder parkinson's disease cardiomyopathy
mitochondrial complex i deficiency schizophrenia blepharospasm intrahepatic cholangiocarcinoma
huntington's disease cholangiocarcinoma cerebritis tuberculosis
prostatitis mycobacterium tuberculosis
2 diseases from the University of Copenhagen DISEASES database for NDUFV2:Bipolar I disorder Schizophrenia Genetic Association Database (GAD): NDUFV2
Human Genome Epidemiology (HuGE) Navigator: NDUFV2 (20 documents)
Export disorders for NDUFV2 gene to outside databases
|
Publications
for NDUFV2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NDUFV2 gene, integrated from 9 sources (see all 43):
(articles sorted by number of sources associating them with NDUFV2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular cloning and characterization of the active human mitochondrial NADH:ubiquinone oxidoreductase 24-kDa gene (NDUFV2) and its pseudogene. (PubMed id 7607668)1, 3, 9 de Coo R....van Oost B. (1995)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Association of mitochondrial complex I subunit gene NDUFV2 at 18p11 with bipolar disorder in Japanese and the National Institute of Mental Health pedigrees. (PubMed id 15450783)1, 4 Washizuka S....Kato T. (2004)
- The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification. (PubMed id 12611891)1, 2 Murray J.... Capaldi R.A. (2003)
- Association of mitochondrial complex I subunit gene NDUFV2 at 18p11 with bipolar disorder. (PubMed id 12815743)1, 4 Washizuka S....Kato T. (2003)
- Mitochondrial complex I polymorphism and cigarette smoking in Parkinson's disease. (PubMed id 12391372)1, 4 Tan E.K....Wong M.C. (2002)
- Intron based radiation hybrid mapping of 15 complex I genes of the human electron transport chain. (PubMed id 9763677)1, 3 Emahazion T....Brookes A.J. (1998)
- Mitochondrial NADH-ubiquinone reductase: complementary DNA sequences of import precursors of the bovine and human 24-kDa subunit. (PubMed id 2500970)1, 2 Pilkington S.J. and Walker J.E. (1989)
- Mutant NDUFV2 subunit of mitochondrial complex I causes early onset hypertrophic cardiomyopathy and encephalopathy. (PubMed id 12754703)1, 9 Benit P....Munnich A. (2003)
- Genotype in the 24-kDa subunit gene (NDUFV2) of mitochondrial complex I and susceptibility to Parkinson disease. (PubMed id 9570948)1, 9 Hattori N.... Mizuno Y. (1998)
|
External Searches for NDUFV2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing NDUFV2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NDUFV2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NDUFV2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for NDUFV2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for NDUFV2 gene:
Search GeneIP for patents involving NDUFV2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for NDUFV2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
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| | |  | OriGene Antibodies for NDUFV2 | | OriGene shRNA RFP for NDUFV2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NDUFV2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NDUFV2 | | | OriGene Protein Over-expression Lysate for NDUFV2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for NDUFV2 | | OriGene 3'-UTR Clone for NDUFV2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NDUFV2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NDUFV2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for NDUFV2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for NDUFV2 | | OriGene Custom Protein Services for NDUFV2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NDUFV2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NDUFV2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NDUFV2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NDUFV2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NDUFV2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NDUFV2 |
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| | | | Search Tocris compounds for NDUFV2 |
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 | | | NDUFV2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | ThermoFisher Antibody for NDUFV2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NDUFV2 |
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