Aliases for NDUFC2-KCTD14 Gene
External Ids for NDUFC2-KCTD14 Gene
Previous GeneCards Identifiers for NDUFC2-KCTD14 Gene
This locus represents naturally occurring read-through transcription between the neighboring NDUFC2 (NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa) and KCTD14 (potassium channel tetramerisation domain containing 14) genes on chromosome 11. The read-through transcripts share sequence identity with the upstream gene product and one variant has a frameshifted C-terminal region derived from the downstream gene exons. [provided by RefSeq, Feb 2011]
GeneCards Summary for NDUFC2-KCTD14 Gene
NDUFC2-KCTD14 (NDUFC2-KCTD14 Readthrough) is a Protein Coding gene. Among its related pathways are Alzheimer's disease and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. GO annotations related to this gene include NADH dehydrogenase (ubiquinone) activity. An important paralog of this gene is NDUFC2.
UniProtKB/Swiss-Prot for NDUFC2-KCTD14 Gene
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).