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NDUFB9 Gene

protein-coding   GIFtS: 61
GCID: GC08P125551

NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 9, 22kDa

(Previous names: NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9 (22kD,...)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 9, 22kDa1 2     LYR Motif-Containing Protein 32 3
UQOR222 3 5     NADH-Ubiquinone Oxidoreductase B22 Subunit2 3
Complex I B22 Subunit1 2     NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 9 (22kD, B22)1
Complex I-B222 3     B222
CI-B222 3     NADH Dehydrogenase [Ubiquinone] 1 Beta Subcomplex Subunit 92
LYRM32 3     

External Ids:    HGNC: 77041   Entrez Gene: 47152   Ensembl: ENSG000001476847   OMIM: 6014455   UniProtKB: Q9Y6M93   

Export aliases for NDUFB9 gene to outside databases

Previous GC identifers: GC08P124713 GC08P125555 GC08P125220 GC08P125507 GC08P125620 GC08P120876


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for NDUFB9 Gene:
NDUFB9 (NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa) is a protein-coding gene. Diseases associated with NDUFB9 include osgood-schlatter's disease, and mitochondrial complex i deficiency. GO annotations related to this gene include NADH dehydrogenase (ubiquinone) activity.

UniProtKB/Swiss-Prot: NDUB9_HUMAN, Q9Y6M9
Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that
is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the
respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Gene Wiki entry for NDUFB9 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000008.11  NC_018919.2  NT_008046.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the NDUFB9 gene promoter:
         HOXA9B   HOXA9   TBP   MEF-2   AREB6   POU2F1   POU2F1a   Meis-1a   aMEF-2   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNDUFB9 promoter sequence
   Search Chromatin IP Primers for NDUFB9

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NDUFB9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q13.3   Ensembl cytogenetic band:  8q24.13   HGNC cytogenetic band: 8q24.13

NDUFB9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NDUFB9 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08P125551:  view genomic region     (about GC identifiers)

Start:
125,551,343 bp from pter      End:
125,580,751 bp from pter
Size:
29,409 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: NDUB9_HUMAN, Q9Y6M9 (See protein sequence)
Recommended Name: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9  
Size: 179 amino acids; 21831 Da
Subunit: Mammalian complex I is composed of 45 different subunits
Secondary accessions: B2R8M6 Q9UQE8

Explore the universe of human proteins at neXtProt for NDUFB9: NX_Q9Y6M9

Explore proteomics data for NDUFB9 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys15
  • Modification sites at PhosphoSitePlus

  • See NDUFB9 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001265574.1  NP_001265575.1  NP_004996.1  

    ENSEMBL proteins: 
     ENSP00000276689   ENSP00000428282   ENSP00000431115   ENSP00000430322  
    Reactome Protein details: Q9Y6M9

    NDUFB9 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    comI: Mitochondrial respiratory chain complex / Complex I
    LYRM: LYR motif containing

    1 InterPro protein domain:
     IPR008011 Complex1_LYR

    Graphical View of Domain Structure for InterPro Entry Q9Y6M9

    ProtoNet protein and cluster: Q9Y6M9

    1 Blocks protein domain: IPB008011 Complex 1 LYR protein

    UniProtKB/Swiss-Prot: NDUB9_HUMAN, Q9Y6M9
    Similarity: Belongs to the complex I LYR family


    NDUFB9 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NDUB9_HUMAN, Q9Y6M9
    Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that
    is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the
    respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

         Genatlas biochemistry entry for NDUFB9:
    NADH ubiquinone oxidoreductase (Q reductase),22kDa,component beta 9,hydrophobic fraction of the complex I
    multi-subunit enzyme of the oxidative phosphorylation,(OXPHOS),inner mitochondrial membrane,homologous to bovine
    subunit,B22

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008137NADH dehydrogenase (ubiquinone) activity NAS9878551
         
    NDUFB9 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NDUFB9
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    miRNA
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    hsa-miR-2909 hsa-miR-1296
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NDUB9_HUMAN, Q9Y6M9: Mitochondrion inner membrane; Peripheral membrane protein; Matrix side
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    cytosol1
    extracellular1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ----
    GO:0005743mitochondrial inner membrane TAS--
    GO:0005747mitochondrial respiratory chain complex I NAS9878551

    NDUFB9 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for NDUFB9 About    
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.0.81
    Parkinson's disease0.57
    Respiratory electron transport0.81
    Oxidative phosphorylation0.51
    Electron Transport Chain0.75
    Huntington's disease0.45
    The citric acid (TCA) cycle and respiratory electron transport0.71
    Non-alcoholic fatty liver disease (NAFLD)0.41
    2Metabolism
    Metabolism0.38
    Metabolic pathways0.38
    3Alzheimer's disease
    Alzheimer's disease0.44

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 BioSystems Pathways for NDUFB9
        Oxidative phosphorylation
    Electron Transport Chain

    1 Reactome Pathway for NDUFB9
        Respiratory electron transport


    Selected Kegg Pathways  (Kegg details for NDUFB9) (see all 6):
        Oxidative phosphorylation
    Metabolic pathways
    Non-alcoholic fatty liver disease (NAFLD)
    Alzheimer's disease
    Parkinson's disease


    NDUFB9 for pathways           About GeneDecksing

        Pathway & Disease-focused RT2 Profiler PCR Array including NDUFB9: 
              Mitochondrial Energy Metabolism in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for NDUFB9

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for NDUFB9 (Q9Y6M92, 3 ENSP000002766894) via UniProtKB, MINT, STRING, and/or I2D (see all 71)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FEZ1Q996892, 3MINT-65872 I2D: score=5 
    GDF9O603832, 3MINT-65868 I2D: score=5 
    IMMTQ168912, 3MINT-65870 I2D: score=5 
    SH3GL3Q999632, 3MINT-65873 I2D: score=5 
    HAP1P542572, 3MINT-65869 I2D: score=4 
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006120mitochondrial electron transport, NADH to ubiquinone NAS9878551
    GO:0007605sensory perception of sound TAS8661098
    GO:0022904respiratory electron transport chain TAS--
    GO:0044237cellular metabolic process TAS--
    GO:0044281small molecule metabolic process TAS--

    NDUFB9 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NDUFB9 (NDUB9)

    8 HMDB Compounds for NDUFB9    About this table
    CompoundSynonyms CAS #PubMed Ids
    FAD1H-Purin-6-amine flavin dinucleotide (see all 21)146-14-5--
    IronArmco iron (see all 19)7439-89-6--
    NAD3-Carbamoyl-1-D-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate (see all 28)53-84-9--
    NADH1,4-Dihydronicotinamide adenine dinucleotide (see all 17)58-68-4--
    QH2CoQH2 (see all 5)56275-39-9--
    SulfideSulfide (see all 4)18496-25-8--
    Ubiquinone Q1Coenzyme Q (see all 9)727-81-1--
    Ubiquinone Q22-(3,7-dimethyl-2,6-octadienyl)-5,6-dimethoxy-3-methyl-2,5-Cyclohexadiene-1,4-dione (see all 7)606-06-4--

    1 DrugBank Compound for NDUFB9    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    NADHbeta-DPNH (see all 18)606-68-8target--17139284 17016423



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for NDUFB9 gene (3 alternative transcripts): 
    NM_001278645.1  NM_001278646.1  NM_005005.2  

    Unigene Cluster for NDUFB9:

    NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa
    Hs.15977  [show with all ESTs]
    Unigene Representative Sequence: BF568951
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000276689(uc003yrg.4) ENST00000518008 ENST00000522532(uc011lim.1)
    ENST00000517367 ENST00000518657 ENST00000524241 ENST00000517830
    miRNA
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    hsa-miR-2909 hsa-miR-1296
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    Inhib. RNA
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      QuantiFast Probe-based Assays in human, mouse, rat NDUFB9

    Additional mRNA sequence: 

    AF044956.1 AF067168.1 AF261090.1 AK026538.1 AK302286.1 AK313432.1 AL136714.1 BC007672.2 
    S82655.1 

    17 DOTS entries:

    DT.95313659  DT.99960191  DT.218477  DT.95211164  DT.100819758  DT.91760864  DT.95170457  DT.100819760 
    DT.100819768  DT.100819766  DT.121486200  DT.100758336  DT.121486231  DT.91760865  DT.95242202  DT.121486325 
    DT.95328618 

    Selected AceView cDNA sequences (see all 591):

    BM808519 BM809263 BM767408 BP369114 CB159252 AA478103 CA778344 AA437360 
    F34836 BU172256 BM916684 CR598184 BQ063782 AI076945 AA320718 BC007672 
    BM911421 BQ676628 CA433657 BM766724 AA316049 BU839189 BU538687 BQ933123 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for NDUFB9 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b
    SP1:                                                        -               
    SP2:                                      -                 -               
    SP3:                                      -                 -               
    SP4:                                                        -               
    SP5:                                                                        


    ECgene alternative splicing isoforms for NDUFB9

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NDUFB9 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    NDUFB9 Expression
    About this image


    NDUFB9 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 19) fully expand
     
     Brain (Nervous System)
             Cerebral Cortex
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Colon (Gastrointestinal Tract)
     
     Uterus (Reproductive System)
     
     Thyroid (Endocrine System)
    NDUFB9 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NDUFB9 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.15977
        Pathway & Disease-focused RT2 Profiler PCR Array including NDUFB9: 
              Mitochondrial Energy Metabolism in human mouse rat

    Primer
    Products:
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NDUFB9

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

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    This gene was present in the common ancestor of animals.

    Orthologs for NDUFB9 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ndufb91 , 5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, more1, 5 86.7(n)1
    87.08(a)1
      15 (25.09 cM)5
    662181  NM_023172.31  NP_075661.11 
     589338105 
    chicken
    (Gallus gallus)
    Aves NDUFB91 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, more 77.84(n)
    79.19(a)
      420337  XM_418444.4  XP_418444.3 
    lizard
    (Anolis carolinensis)
    Reptilia NDUFB96
    NADH dehydrogenase (ubiquinone) 1 beta subcomplex,...
    84(a)
    1 ↔ 1
    4(6255912-6262170)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.46272 Xenopus laevis transcribed sequence with moderate similarity more 76.03(n)    48051652 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb10b032 Transcribed sequence with moderate similarity to protein more 76.39(n)    57075974 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG93061 CG9306 54.57(n)
    48.39(a)
      34747  NM_135798.2  NP_609642.1 
    worm
    (Caenorhabditis elegans)
    Secernentea C16A3.51 C16A3.5 46.28(n)
    36.69(a)
      175904  NM_065995.6  NP_498396.1 


    ENSEMBL Gene Tree for NDUFB9 (if available)
    TreeFam Gene Tree for NDUFB9 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NDUFB9 gene
    1 SIMAP similar gene for NDUFB9 using alignment to 4 protein entries:     NDUB9_HUMAN (see all proteins):
    DKFZp566O173

    NDUFB9 for paralogs           About GeneDecksing


    4 Pseudogenes.org Pseudogenes for NDUFB9
    PGOHUM00000235618 PGOHUM00000232997 PGOHUM00000249482 PGOHUM00000260747


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NDUFB9 (see all 203)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1473890421,2
    C--125553385(+) CTGGGC/TGACAA 1 -- int10--------
    rs1409186001,2
    --125553392(+) ACAAGA/TGTGAA 1 -- int10--------
    rs1885766261,2
    --125553476(+) TAAATC/TCTTTG 1 -- int10--------
    rs1424190321,2
    --125553591(+) CAGAAC/TTGTTC 1 -- int10--------
    rs1135399351,2
    F--125553633(+) AACACC/ACATAC 1 -- int11Minor allele frequency- A:0.50CSA 2
    rs1488724341,2
    C--125553639(+) CATAC-/TCATAC 1 -- int10--------
    rs1852535081,2
    --125553649(+) CACCAA/TGTATA 1 -- int10--------
    rs1509009691,2
    --125553717(+) TTTAAC/TACTTG 1 -- int10--------
    rs1147479591,2
    C,F--125553737(+) AGGCAC/TTTTTT 1 -- int11Minor allele frequency- T:0.03WA 118
    rs727147041,2
    C--125553867(+) TAGACG/AGAGTT 1 -- int14Minor allele frequency- A:0.10CSA WA NA EA 360

    HapMap Linkage Disequilibrium report for NDUFB9 (125551343 - 125580751 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for NDUFB9: --
    Human Gene Mutation Database (HGMD): NDUFB9
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NDUFB9
    DNA2.0 Custom Variant and Variant Library Synthesis for NDUFB9

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 601445   
    OMIM disorders: 252010  
    12 diseases for NDUFB9:    
    About MalaCards
    osgood-schlatter's disease    mitochondrial complex i deficiency    toxoplasmosis    huntington's disease
    fatty liver disease    parkinson's disease    liver disease    alzheimer's disease
    malaria    schizophrenia    prostate cancer    prostatitis

    1 disease from the University of Copenhagen DISEASES database for NDUFB9:
    Osgood-Schlatter's disease

    NDUFB9 for disorders           About GeneDecksing

    Genetic Association Database (GAD): NDUFB9
    Human Genome Epidemiology (HuGE) Navigator: NDUFB9 (4 documents)

    Export disorders for NDUFB9 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NDUFB9 gene, integrated from 10 sources (see all 35):
    (articles sorted by number of sources associating them with NDUFB9)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    2. Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey. (PubMed id 18977241)1, 4 Starr J.M....Deary I.J. (Mech. Ageing Dev. 2008)
    3. Polymorphisms in mitochondrial genes and prostate cancer risk. (PubMed id 19064571)1, 4 Wang L....Thibodeau S.N. (amp 2008)
    4. A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition. (PubMed id 17601350)1, 4 Harris S.E....Deary I.J. (BMC Genet. 2007)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification. (PubMed id 12611891)1, 2 Murray J.... Capaldi R.A. (J. Biol. Chem. 2003)
    7. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (Genome Res. 2000)
    8. cDNA cloning by amplification of circularized first strand cDNAs reveals non-IRE-regulated iron-responsive mRNAs. (PubMed id 10944468)1, 2 Ye Z. and Connor J.R. (Biochem. Biophys. Res. Commun. 2000)
    9. Human NDUFB9 gene: genomic organization and a possible candidate gene associated with deafness disorder mapped to chromosome 8q13. (PubMed id 10077726)1, 2 Lin X.... Kumar S. (Hum. Hered. 1999)
    10. The human B22 subunit of the NADH-ubiquinone oxidoreductase maps to the region of chromosome 8 involved in branchio-oto-renal syndrome. (PubMed id 8661098)1, 3 Gu J.Z.... Wells D.E. (Genomics 1996)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 4715 HGNC: 7704 AceView: NDUFB9 Ensembl:ENSG00000147684 euGenes: HUgn4715
    ECgene: NDUFB9 Kegg: 4715 H-InvDB: NDUFB9

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NDUFB9 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NDUFB9 gene:
    Search GeneIP for patents involving NDUFB9

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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