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NDUFB7 Gene

protein-coding   GIFtS: 60
GCID: GC19M014676

NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 7, 18kDa

(Previous names: NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7 (18kD,...)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 7, 18kDa1 2     CI-B182 3
NADH-Ubiquinone Oxidoreductase B18 Subunit1 2 3     NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 7 (18kD, B18)1
Complex I B18 Subunit1 2     B182
Cell Adhesion Protein SQM12 3     NADH Dehydrogenase [Ubiquinone] 1 Beta Subcomplex Subunit 72
Complex I-B182 3     

External Ids:    HGNC: 77021   Entrez Gene: 47132   Ensembl: ENSG000000997957   OMIM: 6038425   UniProtKB: P175683   

Export aliases for NDUFB7 gene to outside databases

Previous GC identifers: GC19M015031 GC19M014522 GC19M014537 GC19M014246


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for NDUFB7 Gene:
The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I).
Mammalian complex I is composed of 45 different subunits. It is located at the mitochondrial inner membrane. This
protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the
respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (provided by
RefSeq, Jul 2008)

GeneCards Summary for NDUFB7 Gene:
NDUFB7 (NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa) is a protein-coding gene. Diseases associated with NDUFB7 include intrahepatic cholangiocarcinoma, and cholangiocarcinoma. GO annotations related to this gene include NADH dehydrogenase (ubiquinone) activity.

UniProtKB/Swiss-Prot: NDUB7_HUMAN, P17568
Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that
is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the
respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Gene Wiki entry for NDUFB7 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000019.10  NC_018930.2  NT_011295.12  
Regulatory elements:
   Regulatory transcription factor binding sites in the NDUFB7 gene promoter:
         RFX1   AML1a   Pbx1a   STAT5A   NF-kappaB   GATA-1   PPAR-gamma1   PPAR-gamma2   ZID   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNDUFB7 promoter sequence
   Search Chromatin IP Primers for NDUFB7

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NDUFB7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.12   Ensembl cytogenetic band:  19p13.12   HGNC cytogenetic band: 19p13.12

NDUFB7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NDUFB7 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M014676:  view genomic region     (about GC identifiers)

Start:
14,676,890 bp from pter      End:
14,682,889 bp from pter
Size:
6,000 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: NDUB7_HUMAN, P17568 (See protein sequence)
Recommended Name: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7  
Size: 137 amino acids; 16402 Da
Subunit: Complex I is composed of 45 different subunits
Sequence caution: Sequence=AAA35675.1; Type=Frameshift; Positions=Several;
Secondary accessions: Q6ICN9 Q9UI16

Explore the universe of human proteins at neXtProt for NDUFB7: NX_P17568

Explore proteomics data for NDUFB7 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See NDUFB7 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_004137.2  
    ENSEMBL proteins: 
     ENSP00000473120   ENSP00000215565  
    Reactome Protein details: P17568

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    comI: Mitochondrial respiratory chain complex / Complex I

    1 InterPro protein domain:
     IPR008698 NADH_UbQ_OxRdtase_B18_su

    Graphical View of Domain Structure for InterPro Entry P17568

    ProtoNet protein and cluster: P17568

    1 Blocks protein domain: IPB008698 NADH-ubiquinone oxidoreductase B18 subunit

    UniProtKB/Swiss-Prot: NDUB7_HUMAN, P17568
    Domain: Contains two C-X9-C motifs that are predicted to form a helix-coil-helix structure, permitting the
    formation of intramolecular disulfide bonds
    Similarity: Belongs to the complex I NDUFB7 subunit family


    NDUFB7 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NDUB7_HUMAN, P17568
    Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that
    is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the
    respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

         Genatlas biochemistry entry for NDUFB7:
    NADH ubiquinone oxidoreductase (Q reductase),18kDa,component beta 7,hydrophobic fraction of the complex I
    multi-subunit enzyme of the oxidative phosphorylation (OXPHOS),inner mitochondrial membrane

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003954NADH dehydrogenase activity ----
    GO:0008137NADH dehydrogenase (ubiquinone) activity NAS9878551
         
    NDUFB7 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for NDUFB7:
     Decreased Tat-dependent transc 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NDUFB7
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NDUB7_HUMAN, P17568: Mitochondrion. Mitochondrion inner membrane; Peripheral membrane protein (Probable).
    Mitochondrion intermembrane space
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    extracellular2
    nucleus2
    cytosol1
    plasma membrane1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IDA--
    GO:0005743mitochondrial inner membrane TAS--
    GO:0005747mitochondrial respiratory chain complex I IDA12611891
    GO:0005758mitochondrial intermembrane space IDA--

    NDUFB7 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for NDUFB7 About    
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.0.81
    Parkinson's disease0.57
    Respiratory electron transport0.81
    Oxidative phosphorylation0.51
    Electron Transport Chain0.75
    Huntington's disease0.45
    The citric acid (TCA) cycle and respiratory electron transport0.71
    Non-alcoholic fatty liver disease (NAFLD)0.41
    2Metabolism
    Metabolism0.38
    Metabolic pathways0.38
    3Alzheimer's disease
    Alzheimer's disease0.44

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 BioSystems Pathways for NDUFB7
        Oxidative phosphorylation
    Electron Transport Chain

    1 Reactome Pathway for NDUFB7
        Respiratory electron transport


    Selected Kegg Pathways  (Kegg details for NDUFB7) (see all 6):
        Oxidative phosphorylation
    Metabolic pathways
    Non-alcoholic fatty liver disease (NAFLD)
    Alzheimer's disease
    Parkinson's disease


    NDUFB7 for pathways           About GeneDecksing

        Pathway & Disease-focused RT2 Profiler PCR Array including NDUFB7: 
              Mitochondrial Energy Metabolism in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for NDUFB7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for NDUFB7 (P175683 ENSP000002155654) via UniProtKB, MINT, STRING, and/or I2D (see all 62)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NDUFA2O436783, ENSP000002521024I2D: score=1 STRING: ENSP00000252102
    RBPJQ063303I2D: score=4 
    NDUFC1ENSP000003777704STRING: ENSP00000377770 STRING: ENSP00000265500
    CYC1ENSP000003171594STRING: ENSP00000317159
    MT-CYBENSP000003545544STRING: ENSP00000354554
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006120mitochondrial electron transport, NADH to ubiquinone NAS9878551
    GO:0022904respiratory electron transport chain TAS--
    GO:0044237cellular metabolic process TAS--
    GO:0044281small molecule metabolic process TAS--

    NDUFB7 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NDUFB7 (NDUB7)

    8 HMDB Compounds for NDUFB7    About this table
    CompoundSynonyms CAS #PubMed Ids
    FAD1H-Purin-6-amine flavin dinucleotide (see all 21)146-14-5--
    IronArmco iron (see all 19)7439-89-6--
    NAD3-Carbamoyl-1-D-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate (see all 28)53-84-9--
    NADH1,4-Dihydronicotinamide adenine dinucleotide (see all 17)58-68-4--
    QH2CoQH2 (see all 5)56275-39-9--
    SulfideSulfide (see all 4)18496-25-8--
    Ubiquinone Q1Coenzyme Q (see all 9)727-81-1--
    Ubiquinone Q22-(3,7-dimethyl-2,6-octadienyl)-5,6-dimethoxy-3-methyl-2,5-Cyclohexadiene-1,4-dione (see all 7)606-06-4--

    1 DrugBank Compound for NDUFB7    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    NADHbeta-DPNH (see all 18)606-68-8target--17139284 17016423 11864782



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for NDUFB7 gene: 
    NM_004146.5  

    Unigene Cluster for NDUFB7:

    NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
    Hs.532853  [show with all ESTs]
    Unigene Representative Sequence: BG745900
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000593353 ENST00000215565(uc002mzg.3)

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    Additional mRNA sequence: 

    AF112200.1 AF217091.1 BC002595.2 CR450354.1 

    9 DOTS entries:

    DT.316326  DT.97771139  DT.95289999  DT.92430525  DT.100789989  DT.121456654  DT.95191564  DT.95289997 
    DT.121456655 

    Selected AceView cDNA sequences (see all 192):

    BU845475 H18124 BE504809 BQ069996 BQ064433 CR610926 BX118330 H50286 
    F37113 BQ070851 AI810836 AV690992 BQ668918 BM665253 AF112200 NM_004146 
    AV689874 AI253656 BM739646 CA337568 BM042463 BM556316 AW515743 BM705074 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for NDUFB7    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b
    SP1:                              
    SP2:                              


    ECgene alternative splicing isoforms for NDUFB7

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NDUFB7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAGGAGTTTG
    NDUFB7 Expression
    About this image


    NDUFB7 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 20) fully expand
     
     Kidney (Urinary System)
             Metanephros
     
     Brain (Nervous System)
             Cerebral Cortex
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Colon (Gastrointestinal Tract)
     
     Uterus (Reproductive System)
    NDUFB7 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NDUFB7 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.532853
        Pathway & Disease-focused RT2 Profiler PCR Array including NDUFB7: 
              Mitochondrial Energy Metabolism in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NDUFB7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for NDUFB7 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ndufb71 , 5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, more1, 5 82.97(n)1
    82.48(a)1
      8 (40.22 cM)5
    669161  NM_025843.31  NP_080119.11 
     835666715 
    lizard
    (Anolis carolinensis)
    Reptilia NDUFB76
    NADH dehydrogenase (ubiquinone) 1 beta subcomplex,...
    76(a)
    1 ↔ 1
    2(102756101-102761150)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.319092 Xenopus laevis transcribed sequence with weak similarity more 73.77(n)    AW640203.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc778202 hypothetical protein MGC77820 73.37(n)   393821  BC062284.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG55481 CG5548 62.27(n)
    52.75(a)
      32434  NM_132765.1  NP_572993.1 
    worm
    (Caenorhabditis elegans)
    Secernentea D2030.46
    Protein D2030.4 (D2030.4) mRNA, complete cds
    50(a)
    1 ↔ 1
    I(7580937-7581628) WBGene00008414


    ENSEMBL Gene Tree for NDUFB7 (if available)
    TreeFam Gene Tree for NDUFB7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NDUFB7 (see all 169)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1168308181,2
    --14677303(+) GCCCTA/GTCCCC 1 -- int10--------
    rs37522211,2
    C,F,H--14677312(+) CCATCA/GAACAG 1 -- int120Minor allele frequency- G:0.18EA NS WA NA CSA 3046
    rs711667581,2
    C--14677418(-) CCAGGC/-CCTGG 1 -- int13Minor allele frequency- -:0.00NA CSA 6
    rs2014358531,2
    --14677540(+) GTTGCA/GGGCCG 1 -- int10--------
    rs2007579721,2
    C--14677608(+) GTGCCA/GCTCCT 2 R W mis10--------
    rs1424234261,2
    F--14677674(+) GAGGTG/AGTGGG 2 /H /Y mis11Minor allele frequency- A:0.00NA 3254
    rs1399814251,2
    C,F--14677711(+) AGCTGC/TGCGTC 2 A syn11Minor allele frequency- T:0.00NA 3518
    rs1485998171,2
    C--14677714(+) TGCGCG/ATCCAT 2 /D syn11Minor allele frequency- A:0.00NA 3628
    rs22284631,2
    C,F--14677732(-) GCCACA/GCAGCA 2 T syn1 ese31Minor allele frequency- G:0.00NA 3672
    rs3698840691,2
    C--14677780(+) CTGGAA/GGCTCC 1 -- int10--------

    HapMap Linkage Disequilibrium report for NDUFB7 (14676890 - 14682889 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for NDUFB7:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2678899CNV Deletion23128226

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NDUFB7
    DNA2.0 Custom Variant and Variant Library Synthesis for NDUFB7

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 603842    OMIM disorders: --

    9 diseases for NDUFB7:    
    About MalaCards
    intrahepatic cholangiocarcinoma    cholangiocarcinoma    huntington's disease    fatty liver disease
    parkinson's disease    malaria    liver disease    alzheimer's disease
    hiv-1


    NDUFB7 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:
    The International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD) 9 - 13 March 2014
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): NDUFB7
    Human Genome Epidemiology (HuGE) Navigator: NDUFB7 (5 documents)

    Export disorders for NDUFB7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NDUFB7 gene, integrated from 10 sources (see all 27):
    (articles sorted by number of sources associating them with NDUFB7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of the human complex I NDUFB7 and 17.2-kDa cDNAs and mutational analysis of 19 genes of the HP fraction in complex I- deficient-patients. (PubMed id 10830904)1, 2, 3 Triepels R....van den Heuvel L. (Hum. Genet. 2000)
    2. NDUFB7 and NDUFA8 are located at the intermembrane surface of complex I. (PubMed id 21310150)1, 2 Szklarczyk R....Huynen M.A. (FEBS Lett. 2011)
    3. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    4. Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. (PubMed id 19343046)1, 4 Saito A....Kamatani N. (J. Hum. Genet. 2009)
    5. Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey. (PubMed id 18977241)1, 4 Starr J.M....Deary I.J. (Mech. Ageing Dev. 2008)
    6. A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition. (PubMed id 17601350)1, 4 Harris S.E....Deary I.J. (BMC Genet. 2007)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification. (PubMed id 12611891)1, 2 Murray J.... Capaldi R.A. (J. Biol. Chem. 2003)
    9. Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)1, 2 Hu R.-M.... Chen J.-L. (Proc. Natl. Acad. Sci. U.S.A. 2000)
    10. Intron based radiation hybrid mapping of 15 complex I genes of the human electron transport chain. (PubMed id 9763677)1, 3 Emahazion T....Brookes A.J. (Cytogenet. Cell Genet. 1998)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 4713 HGNC: 7702 AceView: NDUFB7 Ensembl:ENSG00000099795 euGenes: HUgn4713
    ECgene: NDUFB7 Kegg: 4713 H-InvDB: NDUFB7

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for NDUFB7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for NDUFB7 gene:
    Search GeneIP for patents involving NDUFB7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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