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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NDUFB5 Gene

protein-coding   GIFtS: 56
GCID: GC03P179322

NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 5, 16kDa

(Previous names: NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5 (16kD,...)
Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 5, 16kDa1 2     CISGDH2
Complex I SGDH Subunit1 2     SGDH2
Complex I-SGDH2 3     NADH Dehydrogenase [Ubiquinone] 1 Beta Subcomplex Subunit 5, Mitochondrial2
NADH-Ubiquinone Oxidoreductase SGDH Subunit2 3     CI-SGDH3
NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 5 (16kD, SGDH)1     

External Ids:    HGNC: 77001   Entrez Gene: 47112   Ensembl: ENSG000001365217   OMIM: 6038415   UniProtKB: O436743   

Export aliases for NDUFB5 gene to outside databases

Previous GC identifers: GC03P176087 GC03P180165 GC03P180724 GC03P180643 GC03P180805 GC03P176726


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NDUFB5 Gene:
The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I).
Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This
protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the
respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Three transcript
variants encoding different isoforms have been found for this gene. (provided by RefSeq, Jan 2011)

GeneCards Summary for NDUFB5 Gene: 
NDUFB5 (NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa) is a protein-coding gene. Diseases associated with NDUFB5 include huntington's disease, and parkinson's disease, and among its related super-pathways are Electron Transport Chain and Metabolic pathways. GO annotations related to this gene include NADH dehydrogenase (ubiquinone) activity.

UniProtKB/Swiss-Prot: NDUB5_HUMAN, O43674
Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that
is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the
respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.2  NT_005612.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NDUFB5 gene promoter:
         HOXA9B   HOXA9   Nkx2-2   MIF-1   Meis-1b   Evi-1   HFH-1   COMP1   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNDUFB5 promoter sequence
   Search SABiosciences Chromatin IP Primers for NDUFB5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NDUFB5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q26.33   Ensembl cytogenetic band:  3q26.33   HGNC cytogenetic band: 3q27.1

NDUFB5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NDUFB5 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P179322:  view genomic region     (about GC identifiers)

Start:
179,322,478 bp from pter      End:
179,345,435 bp from pter
Size:
22,958 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NDUB5_HUMAN, O43674 (See protein sequence)
Recommended Name: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial precursor  
Size: 189 amino acids; 21750 Da
Subunit: Complex I is composed of 45 different subunits
Subcellular location: Mitochondrion inner membrane; Single-pass membrane protein; Matrix side
Secondary accessions: Q561V6
Alternative splicing: 2 isoforms:  O43674-1   O43674-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NDUFB5: NX_O43674

Explore proteomics data for NDUFB5 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O43674

  • NDUFB5 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NDUFB5 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001186886.1  NP_001186887.1  NP_002483.1  

    ENSEMBL proteins: 
     ENSP00000259037   ENSP00000419656   ENSP00000419248   ENSP00000420538   ENSP00000353026  
     ENSP00000418354   ENSP00000419099   ENSP00000419501  
    Reactome Protein details: O43674
    Human Recombinant Protein Products for NDUFB5: 
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    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IDA--
    GO:0005743mitochondrial inner membrane TAS--
    GO:0005747mitochondrial respiratory chain complex I NAS9878551
    GO:0016021integral to membrane IEA--

    NDUFB5 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    comI: Mitochondrial respiratory chain complex / Complex I

    1 InterPro protein domain:
     IPR019173 NADH_UbQ_OxRdtase_B5_su

    Graphical View of Domain Structure for InterPro Entry O43674

    ProtoNet protein and cluster: O43674

    UniProtKB/Swiss-Prot: NDUB5_HUMAN, O43674
    Similarity: Belongs to the complex I NDUFB5 subunit family


    NDUFB5 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NDUB5_HUMAN, O43674
    Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that
    is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the
    respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008137NADH dehydrogenase (ubiquinone) activity NAS9878551
         
    NDUFB5 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for NDUFB5:
     Increased gamma-H2AX phosphory 

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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for NDUFB5 About                                                                                                See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.0.81
    Parkinson's disease0.61
    Respiratory electron transport0.81
    Oxidative phosphorylation0.51
    Electron Transport Chain0.75
    Huntington's disease0.47
    The citric acid (TCA) cycle and respiratory electron transport0.72
    Alzheimer's disease0.46
    2Metabolism
    Metabolism0.40
    Metabolic pathways0.40

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 BioSystems Pathways for NDUFB5
        Electron Transport Chain
    Oxidative phosphorylation


    4        Reactome Pathways for NDUFB5
        Respiratory electron transport
    Metabolism
    Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    The citric acid (TCA) cycle and respiratory electron transport


    5/6         Kegg Pathways  (Kegg details for NDUFB5) (see all 6):
        Oxidative phosphorylation
    Metabolic pathways
    Non-alcoholic fatty liver disease (NAFLD)
    Alzheimer's disease
    Parkinson's disease


    NDUFB5 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NDUFB5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/59 Interacting proteins for NDUFB5 (O436743 ENSP000002590374) via UniProtKB, MINT, STRING, and/or I2D (see all 59)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NDUFA2O436783, ENSP000002521024I2D: score=1 STRING: ENSP00000252102
    DGCR14Q96DF83I2D: score=4 
    PAHP004393I2D: score=4 
    NDUFC1ENSP000003777704STRING: ENSP00000377770 STRING: ENSP00000265500
    CYC1ENSP000003171594STRING: ENSP00000317159
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006120mitochondrial electron transport, NADH to ubiquinone NAS9878551
    GO:0022904respiratory electron transport chain TAS--
    GO:0044237cellular metabolic process TAS--
    GO:0044281small molecule metabolic process TAS--

    NDUFB5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NDUFB5 (NDUB5)

    8 HMDB Compounds for NDUFB5    About this table
    CompoundSynonyms CAS #PubMed Ids
    FAD1H-Purin-6-amine flavin dinucleotide (see all 21)146-14-5--
    IronArmco iron (see all 19)7439-89-6--
    NAD3-Carbamoyl-1-D-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate (see all 28)53-84-9--
    NADH1,4-Dihydronicotinamide adenine dinucleotide (see all 17)58-68-4--
    QH2CoQH2 (see all 5)56275-39-9--
    SulfideSulfide (see all 4)18496-25-8--
    Ubiquinone Q1Coenzyme Q (see all 9)727-81-1--
    Ubiquinone Q22-(3,7-dimethyl-2,6-octadienyl)-5,6-dimethoxy-3-methyl-2,5-Cyclohexadiene-1,4-dione (see all 7)606-06-4--

    1 DrugBank Compound for NDUFB5    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    NADHbeta-DPNH (see all 18)606-68-8target--17139284 17016423

    Search CenterWatch for drugs/clinical trials and news about NDUFB5 / NDUB5

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NDUFB5 gene (3 alternative transcripts): 
    NM_001199957.1  NM_001199958.1  NM_002492.3  

    Unigene Cluster for NDUFB5:

    NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
    Hs.730674  [show with all ESTs]
    Unigene Representative Sequence: BX648034
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000488002 ENST00000259037(uc003fkc.3 uc021xhu.1 uc003fke.3 uc003fkd.3)
    ENST00000493866 ENST00000472629 ENST00000468210 ENST00000359944 ENST00000477177
    ENST00000482604 ENST00000480374 ENST00000496904 ENST00000473500 ENST00000491054
    ENST00000471112 ENST00000476587 ENST00000493716

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    Additional mRNA sequence: 

    AF047181.1 AK313822.1 BC005271.1 BC009796.1 BC017909.1 BC093071.1 BX648034.1 

    18 DOTS entries:

    DT.100682805  DT.100824790  DT.454440  DT.100824797  DT.100824800  DT.100824799  DT.95269711  DT.120844773 
    DT.100824791  DT.40111442  DT.100824801  DT.120844812  DT.100824793  DT.40109183  DT.120844821  DT.92466713 
    DT.96086725  DT.97796732 

    24/690 AceView cDNA sequences (see all 690):

    CR616403 AA765390 AA844418 BF221542 AV725044 CK430547 BM055153 BM664758 
    AW467062 BE379983 BG531242 BF116014 BU948078 AI298131 BU738342 BM693161 
    AA936534 BC009796 AA748331 CD672117 BU951984 AA282666 AA778790 BU620913 

    GeneLoc Exon Structure

    5/11 Alternative Splicing Database (ASD) splice patterns (SP) for NDUFB5 (see all 11)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g · 1h ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b · 8c · 8d · 8e · 8f · 8g · 8h
    SP1:                                                  -     -           -                 -                                                         
    SP2:                                                        -     -     -                 -                                                         
    SP3:                                                  -     -     -     -                 -                                                         
    SP4:                                                  -     -     -     -                 -                                                         
    SP5:                                                  -     -           -                 -     -                                                   


    ECgene alternative splicing isoforms for NDUFB5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NDUFB5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGAGAGGAGA
    NDUFB5 Expression
    About this image


    See NDUFB5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NDUFB5

    SOURCE GeneReport for Unigene cluster: Hs.730674
        SABiosciences Expression via Pathway-Focused PCR Array including NDUFB5: 
              Mitochondrial Energy Metabolism in human mouse rat

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for NDUFB5 gene from 6/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ndufb51 , 5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, more1, 5 78.84(n)1
    75.66(a)1
      3 (15.85 cM)5
    660461  NM_025316.21  NP_079592.21 
     327369905 
    chicken
    (Gallus gallus)
    Aves NDUFB51 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, more 67.03(n)
    64.86(a)
      424978  NM_001006553.1  NP_001006553.1 
    lizard
    (Anolis carolinensis)
    Reptilia NDUFB56
    Uncharacterized protein
    62(a)
    1 ↔ 1
    3(2093917-2101191)
    African clawed frog
    (Xenopus laevis)
    Amphibia ndufb5-prov2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, more 77.63(n)    BC041310.1 
    zebrafish
    (Danio rerio)
    Actinopterygii CB364996.12   -- 74.85(n)   321340  CB364996.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta l(3)neo181 lethal (3) neo18 49.87(n)
    49.61(a)
      46260  NM_143785.2  NP_652042.1 


    ENSEMBL Gene Tree for NDUFB5 (if available)
    TreeFam Gene Tree for NDUFB5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NDUFB5 gene

    NDUFB5 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for NDUFB5
    PGOHUM00000245778 PGOHUM00000241456


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/385 SNPs in NDUFB5 are shown (see all 385)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1445720121,2
    C--179324509(+) TGTGCA/GATAGA 3 -- int10--------
    rs1484554491,2
    C--179324601(+) TTCTCC/GCAGTT 3 -- int10--------
    rs1425468611,2
    --179324631(+) CCACAG/TGATGA 3 -- int10--------
    rs1871487191,2
    --179324666(+) GAAACA/CTGATG 3 -- int10--------
    rs1891041291,2
    --179324830(+) ATTCAA/GTCAAA 3 -- int10--------
    rs738835711,2
    C--179324869(+) TTCACC/TCCCAG 3 -- int14Minor allele frequency- T:0.07WA NA EA 360
    rs1459767501,2
    --179325000(+) TTTTCA/CGCTGT 3 -- int10--------
    rs1814443041,2
    --179325111(+) TAATGC/TAGTAG 3 -- int10--------
    rs1857840381,2
    --179325148(+) GGAGAC/TAGACT 3 -- int10--------
    rs1176474331,2
    F--179325220(+) AAGCTA/CAAGTG 3 -- int11Minor allele frequency- C:0.03EA 120

    HapMap Linkage Disequilibrium report for NDUFB5 (179322478 - 179345435 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for NDUFB5: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing NDUFB5
    DNA2.0 Custom Variant and Variant Library Synthesis for NDUFB5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 603841    OMIM disorders: --

    5 diseases for NDUFB5:    About MalaCards
    huntington's disease    parkinson's disease    schizophrenia    alzheimer's disease
    prostatitis


    NDUFB5 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): NDUFB5
    Human Genome Epidemiology (HuGE) Navigator: NDUFB5 (5 documents)

    Export disorders for NDUFB5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NDUFB5 gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with NDUFB5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and primary structure of five human NADH-ubiquinone oxidoreductase subunits. (PubMed id 9425316)1, 2, 3 Ton C....Liew C.C. (1997)
    2. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    3. Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. (PubMed id 19343046)1, 4 Saito A....Kamatani N. (2009)
    4. Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey. (PubMed id 18977241)1, 4 Starr J.M....Deary I.J. (2008)
    5. Polymorphisms in mitochondrial genes and prostate can cer risk. (PubMed id 19064571)1, 4 Wang L....Thibodeau S.N. (2008)
    6. A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition. (PubMed id 17601350)1, 4 Harris S.E....Deary I.J. (2007)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification. (PubMed id 12611891)1, 2 Murray J.... Capaldi R.A. (2003)
    9. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 4711 HGNC: 7700 AceView: NDUFB5 Ensembl:ENSG00000136521 euGenes: HUgn4711
    ECgene: NDUFB5 Kegg: 4711 H-InvDB: NDUFB5

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NDUFB5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NDUFB5 gene:
    Search GeneIP for patents involving NDUFB5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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