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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NDUFB3 Gene

protein-coding   GIFtS: 55
GCID: GC02P201936

NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 3, 12kDa

(Previous names: NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3 (12kD,...)
Alzheimer's & Parkinson's Diseases Congress
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 3, 12kDa1 2     Complex I B12 Subunit1
Complex I-B122 3     NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 3 (12kD, B12)1
CI-B122 3     B122
NADH-Ubiquinone Oxidoreductase B12 Subunit2 3     NADH Dehydrogenase [Ubiquinone] 1 Beta Subcomplex Subunit 32

External Ids:    HGNC: 76981   Entrez Gene: 47092   Ensembl: ENSG000001190137   OMIM: 6038395   UniProtKB: O436763   

Export aliases for NDUFB3 gene to outside databases

Previous GC identifers: GC02P200153 GC02P200661 GC02P201900 GC02P202139 GC02P201762 GC02P201644 GC02P193787


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NDUFB3 Gene:
This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex
I) which is the first enzyme in the electron transport chain of mitochondria. This protein localizes to the inner
membrane of the mitochondrion as a single-pass membrane protein. Mutations in this gene contribute to
mitochondrial complex 1 deficiency. Alternative splicing results in multiple transcript variants encoding the
same protein. Humans have multiple pseudogenes of this gene. (provided by RefSeq, Mar 2012)

GeneCards Summary for NDUFB3 Gene: 
NDUFB3 (NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa) is a protein-coding gene. Diseases associated with NDUFB3 include lateral sclerosis, and amyotrophic lateral sclerosis, and among its related super-pathways are Electron Transport Chain and Metabolic pathways. GO annotations related to this gene include NADH dehydrogenase (ubiquinone) activity.

UniProtKB/Swiss-Prot: NDUB3_HUMAN, O43676
Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that
is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the
respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NT_005403.17  NC_018913.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NDUFB3 gene promoter:
         AML1a   NF-YA   POU6F1 (c2)   NF-YB   HEN1   CBF-B   CBF-A   CP1A   NF-Y   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNDUFB3 promoter sequence
   Search SABiosciences Chromatin IP Primers for NDUFB3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NDUFB3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q31.3   Ensembl cytogenetic band:  2q33.1   HGNC cytogenetic band: 2q33.1

NDUFB3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NDUFB3 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P201936:  view genomic region     (about GC identifiers)

Start:
201,936,156 bp from pter      End:
201,950,473 bp from pter
Size:
14,318 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NDUB3_HUMAN, O43676 (See protein sequence)
Recommended Name: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3  
Size: 98 amino acids; 11402 Da
Subunit: Complex I is composed of 45 different subunits
Subcellular location: Mitochondrion inner membrane; Single-pass membrane protein; Matrix side
Secondary accessions: Q6IB80

Explore the universe of human proteins at neXtProt for NDUFB3: NX_O43676

Explore proteomics data for NDUFB3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O43676

  • NDUFB3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NDUFB3 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001244031.1  NP_002482.1  

    ENSEMBL proteins: 
     ENSP00000401834   ENSP00000237889   ENSP00000410600   ENSP00000407336  
    Reactome Protein details: O43676
    Human Recombinant Protein Products for NDUFB3: 
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    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ----
    GO:0005743mitochondrial inner membrane TAS--
    GO:0005747mitochondrial respiratory chain complex I NAS9878551
    GO:0016021integral to membrane IEA--

    NDUFB3 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    comI: Mitochondrial respiratory chain complex / Complex I

    1 InterPro protein domain:
     IPR012576 NADH_UbQ_OxRdtase_B12_su

    Graphical View of Domain Structure for InterPro Entry O43676

    ProtoNet protein and cluster: O43676

    1 Blocks protein domain: IPB012576 NADH-ubiquinone oxidoreductase B12 subunit

    UniProtKB/Swiss-Prot: NDUB3_HUMAN, O43676
    Similarity: Belongs to the complex I NDUFB3 subunit family


    NDUFB3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NDUB3_HUMAN, O43676
    Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that
    is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the
    respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008137NADH dehydrogenase (ubiquinone) activity NAS9878551
         
    NDUFB3 for ontologies           About GeneDecksing


    Animal Models:
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for NDUFB3 About                                                                                                See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.0.81
    Parkinson's disease0.61
    Respiratory electron transport0.81
    Huntington's disease0.47
    Electron Transport Chain0.75
    Alzheimer's disease0.46
    The citric acid (TCA) cycle and respiratory electron transport0.72
    Non-alcoholic fatty liver disease (NAFLD)0.41
    2Metabolism
    Metabolism0.40
    Metabolic pathways0.40

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for NDUFB3
        Electron Transport Chain

    4        Reactome Pathways for NDUFB3
        Respiratory electron transport
    Metabolism
    Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    The citric acid (TCA) cycle and respiratory electron transport


    5/6         Kegg Pathways  (Kegg details for NDUFB3) (see all 6):
        Oxidative phosphorylation
    Metabolic pathways
    Non-alcoholic fatty liver disease (NAFLD)
    Alzheimer's disease
    Parkinson's disease


    NDUFB3 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NDUFB3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/56 Interacting proteins for NDUFB3 (O436762, 3 ENSP000002378894) via UniProtKB, MINT, STRING, and/or I2D (see all 56)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATP5C1P365422, 3, ENSP000003491424MINT-63700 I2D: score=5 STRING: ENSP00000349142
    NDUFA2O436783, ENSP000002521024I2D: score=1 STRING: ENSP00000252102
    NDUFC1ENSP000003777704STRING: ENSP00000377770 STRING: ENSP00000265500
    CYC1ENSP000003171594STRING: ENSP00000317159
    ENSG00000267059ENSP000002629464STRING: ENSP00000262946
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006120mitochondrial electron transport, NADH to ubiquinone NAS9878551
    GO:0022904respiratory electron transport chain TAS--
    GO:0044237cellular metabolic process TAS--
    GO:0044281small molecule metabolic process TAS--

    NDUFB3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NDUFB3 (NDUB3)

    8 HMDB Compounds for NDUFB3    About this table
    CompoundSynonyms CAS #PubMed Ids
    FAD1H-Purin-6-amine flavin dinucleotide (see all 21)146-14-5--
    IronArmco iron (see all 19)7439-89-6--
    NAD3-Carbamoyl-1-D-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate (see all 28)53-84-9--
    NADH1,4-Dihydronicotinamide adenine dinucleotide (see all 17)58-68-4--
    QH2CoQH2 (see all 5)56275-39-9--
    SulfideSulfide (see all 4)18496-25-8--
    Ubiquinone Q1Coenzyme Q (see all 9)727-81-1--
    Ubiquinone Q22-(3,7-dimethyl-2,6-octadienyl)-5,6-dimethoxy-3-methyl-2,5-Cyclohexadiene-1,4-dione (see all 7)606-06-4--

    1 DrugBank Compound for NDUFB3    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    NADHbeta-DPNH (see all 18)606-68-8target--17139284 17016423

    Search CenterWatch for drugs/clinical trials and news about NDUFB3 / NDUB3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NDUFB3 gene (2 alternative transcripts): 
    NM_001257102.1  NM_002491.2  

    Unigene Cluster for NDUFB3:

    NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
    Hs.109760  [show with all ESTs]
    Unigene Representative Sequence: BM552702
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000450023 ENST00000237889(uc002uwx.4) ENST00000433898 ENST00000454214


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    Additional mRNA sequence: 

    AF035839.1 AF047183.1 BC018183.1 CR456924.1 

    10 DOTS entries:

    DT.447331  DT.99956714  DT.120963492  DT.97784860  DT.95092387  DT.100692775  DT.95092411  DT.91743226 
    DT.91743227  DT.91841399 

    24/256 AceView cDNA sequences (see all 256):

    BG387988 AA932871 F36305 AI167776 AA883278 AA384898 AA845535 BM685048 
    BC018183 AA527316 W52717 BM848639 AW008598 AA634495 BU743166 AA776653 
    F36304 AA149584 W51839 CK906101 BM724744 CK906100 AA127857 F19042 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NDUFB3 expression in normal human tissues (normalized intensities)      NDUFB3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGTGGCTTTG
    NDUFB3 Expression
    About this image


    NDUFB3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/14 selected tissues (see all 14) fully expand
     
     Brain (Nervous System)    fully expand to see all 6 entries
             Cerebral Cortex
             brain/midbrain   
     
     Heart (Cardiovascular System)    fully expand to see all 3 entries
             heart/ventricle   
     
     Nose (Sensory Organs)    fully expand to see all 2 entries
             sensory organ/nose/nasal cavity   
     
     Limb (Muscoskeletal System)    fully expand to see all 2 entries
             limb/hindlimb   
     
     Lung (Respiratory System)
             Stem Bronchi

    See NDUFB3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NDUFB3

    SOURCE GeneReport for Unigene cluster: Hs.109760
        SABiosciences Expression via Pathway-Focused PCR Array including NDUFB3: 
              Mitochondrial Energy Metabolism in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NDUFB3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for NDUFB3 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ndufb31 , 5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex 31, 5 83.33(n)1
    82.29(a)1
      1 (29.13 cM)5
    664951  NM_025597.21  NP_079873.11 
     585863845 
    chicken
    (Gallus gallus)
    Aves NDUFB31 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, more 67.35(n)
    64.29(a)
      424078  XM_001232007.2  XP_001232008.1 
    lizard
    (Anolis carolinensis)
    Reptilia NDUFB36
    Uncharacterized protein
    63(a)
    1 ↔ 1
    GL343478.1(445742-449601)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.195602 Xenopus laevis transcribed sequence with weak similarity more 72.28(n)    AW637187.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1003320341 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit more 60.93(n)
    64.52(a)
      100332034  XM_002663290.2  XP_002663336.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG103206
    --
    34(a)
    1 ↔ 1
    2R(17545580-17546282)


    ENSEMBL Gene Tree for NDUFB3 (if available)
    TreeFam Gene Tree for NDUFB3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NDUFB3 gene

    NDUFB3 for paralogs           About GeneDecksing


    4 Pseudogenes.org Pseudogenes for NDUFB3
    PGOHUM00000250146 PGOHUM00000250154 PGOHUM00000251068 PGOHUM00000250090


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/287 SNPs in NDUFB3 are shown (see all 287)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1476873571,2
    C--201324154(+) AGAAC-/AAAAAC 2 -- us2k10--------
    rs761526101,2
    F--201324409(+) CACTAC/TATTAG 2 -- us2k11Minor allele frequency- T:0.03WA 118
    rs1922570061,2
    C--201324426(+) TCTCCC/TAAGCT 2 -- us2k10--------
    rs1852688501,2
    --201324564(+) TTCCAC/TAACAC 2 -- us2k10--------
    rs41477851,2
    C,F,H--201324788(+) TTTCTG/ACCRGG 2 -- us2k110Minor allele frequency- A:0.02NS EA NA 1552
    rs1880901151,2
    --201324789(+) TTCTGC/GCGGGC 2 -- us2k10--------
    rs1928761831,2
    C--201324867(+) AGTTCC/GAGACC 2 -- us2k10--------
    rs1845989511,2
    --201324919(+) CAAAAA/TTAGTC 2 -- us2k10--------
    rs790530271,2
    C--201325039(+) CTCCAG/TCCTGG 2 -- us2k10--------
    rs747973511,2
    C,F--201325093(+) TTTTTT/CCCCCA 2 -- us2k12Minor allele frequency- C:0.13WA 120

    HapMap Linkage Disequilibrium report for NDUFB3 (201936156 - 201950473 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for NDUFB3: --

    Human Gene Mutation Database (HGMD): NDUFB3
    SABiosciences Cancer Mutation PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing NDUFB3
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 603839    OMIM disorders: --

    6 diseases for NDUFB3:    About MalaCards
    lateral sclerosis    amyotrophic lateral sclerosis    huntington's disease    parkinson's disease
    gastric cancer    alzheimer's disease

    1 disease from the University of Copenhagen DISEASES database for NDUFB3:
    Leigh disease

    NDUFB3 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): NDUFB3
    Human Genome Epidemiology (HuGE) Navigator: NDUFB3 (2 documents)

    Export disorders for NDUFB3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NDUFB3 gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with NDUFB3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and primary structure of five human NADH-ubiquinone oxidoreductase subunits. (PubMed id 9425316)1, 2, 3 Ton C....Liew C.C. (1997)
    2. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    3. Association between genetic variants in VEGF, ERCC3 a nd occupational benzene haematotoxicity. (PubMed id 19773279)1, 4 Hosgood H.D....Lan Q. (2009)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification. (PubMed id 12611891)1, 2 Murray J.... Capaldi R.A. (2003)
    6. Assignment of human NADH dehydrogenase (ubiquinone) 1 beta subcomplex 3 (NDUFB3) and of its four pseudogenes to human chromosomes 2q31.3, 1p13.3-->p13.1, 9q32-->q34.1, 14q22.3-->q23.1 and 14q32.2 by radiation hybrid mapping. (PubMed id 11474204)1, 3 Jensen L.L....Hansen L.L. (2001)
    7. cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed. (PubMed id 9878551)1, 2 Loeffen J.L....Smeitink J.A. (1998)
    8. Molecular diagnosis of infantile mitochondrial disease with targeted next-generation sequencing. (PubMed id 22277967)1 Calvo S.E.... Mootha V.K. (2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    10. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 4709 HGNC: 7698 AceView: NDUFB3 Ensembl:ENSG00000119013 euGenes: HUgn4709
    ECgene: NDUFB3 Kegg: 4709 H-InvDB: NDUFB3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NDUFB3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NDUFB3 gene:
    Search GeneIP for patents involving NDUFB3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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