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NDUFB2 Gene

protein-coding   GIFtS: 53
GCID: GC07P140390

NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 2, 8kDa

(Previous names: NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2 (8kD,...)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 2, 8kDa1 2     CI-AGGG2 3
NADH-Ubiquinone Oxidoreductase AGGG Subunit1 2 3     NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 2 (8kD, AGGG)1
Complex I AGGG Subunit1 2     AGGG2
Complex I-AGGG2 3     NADH Dehydrogenase [Ubiquinone] 1 Beta Subcomplex Subunit 2, Mitochondrial2

External Ids:    HGNC: 76971   Entrez Gene: 47082   Ensembl: ENSG000000902667   OMIM: 6038385   UniProtKB: O951783   

Export aliases for NDUFB2 gene to outside databases

Previous GC identifers: GC07P138667 GC07P139726 GC07P139803 GC07P139849 GC07P140042 GC07P134692


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for NDUFB2 Gene:
The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I).
Mammalian complex I is composed of 45 different subunits. This protein has NADH dehydrogenase activity and
oxidoreductase activity. It plays a important role in transfering electrons from NADH to the respiratory chain.
The immediate electron acceptor for the enzyme is believed to be ubiquinone. Hydropathy analysis revealed that
this subunit and 4 other subunits have an overall hydrophilic pattern, even though they are found within the
hydrophobic protein (HP) fraction of complex I. (provided by RefSeq, Jul 2008)

GeneCards Summary for NDUFB2 Gene:
NDUFB2 (NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa) is a protein-coding gene. GO annotations related to this gene include NADH dehydrogenase (ubiquinone) activity.

UniProtKB/Swiss-Prot: NDUB2_HUMAN, O95178
Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that
is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the
respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Gene Wiki entry for NDUFB2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000007.13  NC_018918.2  NT_007933.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the NDUFB2 gene promoter:
         c-Fos   RP58   AML1a   AP-1   Bach2   IRF-1   CREB   Max   c-Jun   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): NDUFB2 promoter sequence
   Search Chromatin IP Primers for NDUFB2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NDUFB2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q34   Ensembl cytogenetic band:  7q34   HGNC cytogenetic band: 7q34

NDUFB2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NDUFB2 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P140390:  view genomic region     (about GC identifiers)

Start:
140,390,577 bp from pter      End:
140,422,590 bp from pter
Size:
32,014 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 139,734,658-139,744,623     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: NDUB2_HUMAN, O95178 (See protein sequence)
Recommended Name: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial precursor  
Size: 105 amino acids; 12058 Da
Subunit: Complex I is composed of 45 different subunits
Secondary accessions: Q6FGI6

Explore the universe of human proteins at neXtProt for NDUFB2: NX_O95178

Explore proteomics data for NDUFB2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See NDUFB2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_004537.1  
    ENSEMBL proteins: 
     ENSP00000419392   ENSP00000419087   ENSP00000247866   ENSP00000420062   ENSP00000419357  
     ENSP00000418347   ENSP00000419479   ENSP00000418953   ENSP00000418573   ENSP00000420377  
     ENSP00000419983   ENSP00000418981   ENSP00000204307  
    Reactome Protein details: O95178

    NDUFB2 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    comI: Mitochondrial respiratory chain complex / Complex I

    1 InterPro protein domain:
     IPR026627 NDUFB2

    Graphical View of Domain Structure for InterPro Entry O95178

    ProtoNet protein and cluster: O95178

    UniProtKB/Swiss-Prot: NDUB2_HUMAN, O95178
    Similarity: Belongs to the complex I NDUFB2 subunit family


    Find genes that share domains with NDUFB2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NDUB2_HUMAN, O95178
    Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that
    is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the
    respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

         Genatlas biochemistry entry for NDUFB2:
    NADH ubiquinone oxidoreductase (Q reductase),12.1kDa,component beta 2,hydrophobic fraction of the complex I
    multi-subunit enzyme of the oxidative phosphorylation (OXPHOS),inner mitochondrial membrane

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008137NADH dehydrogenase (ubiquinone) activity NAS9878551
         
    Find genes that share ontologies with NDUFB2           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for NDUFB2

    miRNA
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    miRTarBase miRNAs that target NDUFB2:
    hsa-mir-19b-3p (MIRT031131)

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NDUB2_HUMAN, O95178: Mitochondrion inner membrane; Peripheral membrane protein; Matrix side
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    cytoskeleton1
    cytosol1
    extracellular1
    golgi apparatus1
    nucleus1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ----
    GO:0005743mitochondrial inner membrane TAS--
    GO:0005747mitochondrial respiratory chain complex I NAS9878551

    Find genes that share ontologies with NDUFB2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for NDUFB2 About    
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.0.81
    Parkinson's disease0.57
    Respiratory electron transport0.81
    Oxidative phosphorylation0.51
    Electron Transport Chain0.75
    Huntington's disease0.45
    The citric acid (TCA) cycle and respiratory electron transport0.71
    Non-alcoholic fatty liver disease (NAFLD)0.41
    2Metabolism
    Metabolism0.38
    Metabolic pathways0.38
    3Alzheimer's disease
    Alzheimer's disease0.44


    Find genes that share SuperPaths with NDUFB2           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 BioSystems Pathways for NDUFB2
        Oxidative phosphorylation
    Electron Transport Chain

    1 Reactome Pathway for NDUFB2
        Respiratory electron transport


    Selected Kegg Pathways  (Kegg details for NDUFB2) (see all 6):
        Oxidative phosphorylation
    Metabolic pathways
    Non-alcoholic fatty liver disease (NAFLD)
    Alzheimer's disease
    Parkinson's disease

        Pathway & Disease-focused RT2 Profiler PCR Array including NDUFB2: 
              Mitochondrial Energy Metabolism in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for NDUFB2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for NDUFB2 (ENSP000002478664) via UniProtKB, MINT, STRING, and/or I2D (see all 56)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NDUFC1ENSP000003777704STRING: ENSP00000377770 STRING: ENSP00000265500
    CYC1ENSP000003171594STRING: ENSP00000317159
    MT-ND1ENSP000003546874STRING: ENSP00000354687
    MT-ND2ENSP000003550464STRING: ENSP00000355046
    MT-ND4ENSP000003549614STRING: ENSP00000354961
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006120mitochondrial electron transport, NADH to ubiquinone NAS9878551
    GO:0022904respiratory electron transport chain TAS--
    GO:0044237cellular metabolic process TAS--
    GO:0044281small molecule metabolic process TAS--

    Find genes that share ontologies with NDUFB2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for NDUFB2 (NDUB2)

    8 HMDB Compounds for NDUFB2    About this table
    CompoundSynonyms CAS #PubMed Ids
    FAD1H-Purin-6-amine flavin dinucleotide (see all 21)146-14-5--
    IronArmco iron (see all 19)7439-89-6--
    NAD3-Carbamoyl-1-D-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate (see all 28)53-84-9--
    NADH1,4-Dihydronicotinamide adenine dinucleotide (see all 17)58-68-4--
    QH2CoQH2 (see all 5)56275-39-9--
    SulfideSulfide (see all 4)18496-25-8--
    Ubiquinone Q1Coenzyme Q (see all 9)727-81-1--
    Ubiquinone Q22-(3,7-dimethyl-2,6-octadienyl)-5,6-dimethoxy-3-methyl-2,5-Cyclohexadiene-1,4-dione (see all 7)606-06-4--

    1 DrugBank Compound for NDUFB2    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    NADHbeta-DPNH (see all 18)606-68-8target--17139284 17016423



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for NDUFB2 gene: 
    NM_004546.2  

    Unigene Cluster for NDUFB2:

    NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
    Hs.655788  [show with all ESTs]
    Unigene Representative Sequence: BC065735
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000482954 ENST00000476279 ENST00000247866(uc003vwa.3) ENST00000461457
    ENST00000465506 ENST00000464564 ENST00000476181(uc010lnl.3) ENST00000464566
    ENST00000460088 ENST00000472695 ENST00000476470 ENST00000471136 ENST00000462847
    ENST00000475276 ENST00000479181 ENST00000204307
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    Additional mRNA sequence: 

    AF050639.1 AF067166.1 BC001168.1 BC063026.1 BC065735.1 CR542121.1 

    17 DOTS entries:

    DT.97861846  DT.456322  DT.112008  DT.412400  DT.75196070  DT.100038043  DT.100697142  DT.91753052 
    DT.95149881  DT.95336912  DT.121078780  DT.121078796  DT.100685623  DT.40114578  DT.87015699  DT.95258699 
    DT.456076 

    Selected AceView cDNA sequences (see all 415):

    AA102339 BE906529 CR610711 BQ288025 BE739250 F21673 AA593450 BE745459 
    NM_052853 F18891 CA430229 BQ431052 CB109485 CR615943 BC063026 AI160418 
    CA433542 R64609 BQ689309 BG390000 BU164187 BM768781 F30245 BM709311 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for NDUFB2    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b ^ 5 ^ 6a · 6b
    SP1:                    -                       -     -               
    SP2:              -     -                                             
    SP3:                                            -     -               
    SP4:                                            -                     


    ECgene alternative splicing isoforms for NDUFB2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NDUFB2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACTCAGAAGA
    NDUFB2 Expression
    About this image


    NDUFB2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 19) fully expand
     
     Bone (Muscoskeletal System)    fully expand to see all 3 entries
             Endochondral Facial Bones
     
     Brain (Nervous System)
             Cerebral Cortex
     
     Colon (Gastrointestinal Tract)
     
     Uterus (Reproductive System)
     
     Thyroid (Endocrine System)
    NDUFB2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NDUFB2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.655788
        Pathway & Disease-focused RT2 Profiler PCR Array including NDUFB2: 
              Mitochondrial Energy Metabolism in human mouse rat

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for NDUFB2 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ndufb21 , 5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, more1, 5 81.9(n)1
    82.86(a)1
      6 (18.42 cM)5
    681981  NM_026612.31  NP_080888.11 
     395925745 
    chicken
    (Gallus gallus)
    Aves NDUFB21 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, more 67.02(n)
    72.63(a)
      418118  NM_001277896.1  NP_001264825.1 
    lizard
    (Anolis carolinensis)
    Reptilia NDUFB26
    NADH dehydrogenase (ubiquinone) 1 beta subcomplex,...
    65(a)
    1 ↔ 1
    5(15585525-15587138)
    African clawed frog
    (Xenopus laevis)
    Amphibia ndufb2-prov2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, more 75.17(n)    BC041535.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:733291 zgc:73329 60.48(n)
    52.58(a)
      393764  NM_001167826.1  NP_001161298.1 


    ENSEMBL Gene Tree for NDUFB2 (if available)
    TreeFam Gene Tree for NDUFB2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NDUFB2 gene
    1 SIMAP similar gene for NDUFB2 using alignment to 8 protein entries:     NDUB2_HUMAN (see all proteins):
    WUGSC

    Find genes that share paralogs with NDUFB2           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for NDUFB2
    PGOHUM00000246109


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NDUFB2 (see all 154)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs604109871,2
    C,F--140399203(+) CACCCC/AAATTC 1 -- int13Minor allele frequency- A:0.20WA CSA 122
    rs102469721,2
    C--140399214(+) AGGCtA/Cacatt 1 -- int10--------
    rs1382558561,2
    C--140399308(+) TTCTGA/GTAACA 1 -- int10--------
    rs1864962481,2
    --140399417(+) ACCTTC/GGGTGG 1 -- int10--------
    rs1398394601,2
    C--140399423(+) GTGGG-/CCCCCA 1 -- int10--------
    rs1495637181,2
    C--140399537(+) GTTTTC/TACTTG 1 -- int10--------
    rs69697791,2
    C,F--140399747(+) CAATCC/TTTGTC 1 -- int19Minor allele frequency- T:0.24NA WA CSA EA 370
    rs2005763241,2
    C--140399934(+) TTTTG-/TTTTTTTG 1 -- int10--------
    rs69778341,2
    C,F,A--140399993(+) ATCTCG/AGCTCA 1 -- int13Minor allele frequency- A:0.40NA CSA 5
    rs1133279621,2
    C,F--140400174(+) TGCCTC/TGGCCT 1 -- int12Minor allele frequency- T:0.50WA NA 4

    HapMap Linkage Disequilibrium report for NDUFB2 (140390577 - 140422590 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for NDUFB2:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv831158CNV Loss17160897
    nsv831157CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NDUFB2
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 603838    OMIM disorders: --


    Find genes that share disorders with NDUFB2           About GenesLikeMe

    Genetic Association Database (GAD): NDUFB2
    Human Genome Epidemiology (HuGE) Navigator: NDUFB2 (2 documents)

    Export disorders for NDUFB2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NDUFB2 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with NDUFB2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed. (PubMed id 9878551)1, 2, 3 Loeffen J.L.C.M.... Smeitink J.A.M. (Biochem. Biophys. Res. Commun. 1998)
    2. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    3. Polymorphisms in mitochondrial genes and prostate cancer risk. (PubMed id 19064571)1, 4 Wang L....Thibodeau S.N. (amp 2008)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification. (PubMed id 12611891)1, 2 Murray J.... Capaldi R.A. (J. Biol. Chem. 2003)
    6. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (Genome Res. 2000)
    7. Intron based radiation hybrid mapping of 15 complex I genes of the human electron transport chain. (PubMed id 9763677)1, 3 Emahazion T....Brookes A.J. (Cytogenet. Cell Genet. 1998)
    8. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    9. Global profiling of protease cleavage sites by chemoselective labeling of protein N-termini. (PubMed id 19892738)2 Xu G.... Jaffrey S.R. (Proc. Natl. Acad. Sci. U.S.A. 2009)
    10. Drugs, their targets and the nature and number of drug targets. (PubMed id 17016423)7 Imming P....Meyer A. (Nat Rev Drug Discov 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 4708 HGNC: 7697 AceView: NDUFB2andADCK2 Ensembl:ENSG00000090266 euGenes: HUgn4708
    ECgene: NDUFB2 Kegg: 4708 H-InvDB: NDUFB2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NDUFB2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NDUFB2 gene:
    Search GeneIP for patents involving NDUFB2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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