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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

NDUFB2 Gene

protein-coding GIFtS: 52
GCID: GC07P140390

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa

(Previous names: NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2 (8kD,...)

Explore 6 diseases affiliated with
NDUFB2 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 2, 8kDa¹ ²		NADH-Ubiquinone Oxidoreductase AGGG Subunit² ³
CI-AGGG¹ ² ³		NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 2 (8kD, AGGG)¹
AGGG¹ ²		Complex I AGGG Subunit²
Complex I-AGGG² ³		NADH Dehydrogenase [Ubiquinone] 1 Beta Subcomplex Subunit 2, Mitochondrial²

External Ids:	HGNC: 7697¹	Entrez Gene: 4708²	Ensembl: ENSG00000090266⁷	OMIM: 603838⁵	UniProtKB: O95178³

Export aliases for NDUFB2 gene to outside databases

Previous GC identifers: GC07P138667 GC07P139726 GC07P139803 GC07P139849 GC07P140042 GC07P134692

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NDUFB2:

The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian

complex I is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase

activity. It plays a important role in transfering electrons from NADH to the respiratory chain. The immediate

electron acceptor for the enzyme is believed to be ubiquinone. Hydropathy analysis revealed that this subunit and 4

other subunits have an overall hydrophilic pattern, even though they are found within the hydrophobic protein (HP)

fraction of complex I. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: NDUB2_HUMAN, O95178

Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is

believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the

respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Gene Wiki entry for NDUFB2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000007.13 NC_018918.1 NT_007914.15 NT_079596.2

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the NDUFB2 gene promoter:
c-Fos RP58 AML1a AP-1 Bach2 IRF-1 CREB Max c-Jun c-Myc
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): NDUFB2 promoter sequence

Search SABiosciences Chromatin IP Primers for NDUFB2

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NDUFB2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q34 Ensembl cytogenetic band: 7q34 HGNC cytogenetic band: 7q34

NDUFB2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NDUFB2 gene location

GeneLoc information about chromosome 7 GeneLoc Exon Structure

GeneLoc location for GC07P140390: view genomic region (about GC identifiers)

Start:	140,390,577 bp from pter	End:	140,422,590 bp from pter
Size:	32,014 bases	Orientation:	plus strand

1 alternative location:

Chr7+,CRA_TCAG 139,734,658-139,744,623

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: NDUB2_HUMAN, O95178 (See protein sequence)

Recommended Name: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial precursor

Size: 105 amino acids; 12058 Da

Subunit: Complex I is composed of 45 different subunits

Subcellular location: Mitochondrion inner membrane; Peripheral membrane protein; Matrix side

Secondary accessions: Q6FGI6

Explore the universe of human proteins at neXtProt for NDUFB2: NX_O95178

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_O95178

NDUFB2 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_004537.1

ENSEMBL proteins:

ENSP00000419392 ENSP00000419087 ENSP00000247866 ENSP00000420062 ENSP00000419357

ENSP00000418347 ENSP00000419479 ENSP00000418953 ENSP00000418573 ENSP00000420377

ENSP00000419983 ENSP00000418981 ENSP00000204307

Reactome Protein details: O95178
Human Recombinant Protein Products:

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	Browse ProSpec Recombinant Proteins
	Browse Proteins at Uscn

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005739	mitochondrion	--	--
GO:0005743	mitochondrial inner membrane	TAS	--
GO:0005747	mitochondrial respiratory chain complex I	NAS	9878551

NDUFB2 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

NDUFB2 for domains About GeneDecksing

1 InterPro domain/family:

IPR026627 NDUFB2

Graphical View of Domain Structure for InterPro Entry O95178

ProtoNet protein and cluster: O95178

UniProtKB/Swiss-Prot: NDUB2_HUMAN, O95178

Similarity: Belongs to the complex I NDUFB2 subunit family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: NDUB2_HUMAN, O95178

Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is

believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the

respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Genatlas biochemistry entry for NDUFB2:

NADH ubiquinone oxidoreductase (Q reductase),12.1kDa,component beta 2,hydrophobic fraction of the complex I

multi-subunit enzyme of the oxidative phosphorylation (OXPHOS),inner mitochondrial membrane

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In Situ Assay
Products:

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Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008137	NADH dehydrogenase (ubiquinone) activity	NAS	9878551

NDUFB2 for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.

8/9 pathways (see all 9)
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.	1.00	Parkinson's disease	0.61
Respiratory electron transport	0.81	Oxidative phosphorylation	0.52
Electron Transport Chain	0.76	Alzheimer's disease	0.43
The citric acid (TCA) cycle and respiratory electron transport	0.72	Huntington's disease	0.40

Metabolism

Metabolism

1.00

Metabolic pathways

0.38

Pathway sources
See GeneCards unified pathways
Show all pathways

2 BioSystems Pathways for NDUFB2

	Oxidative phosphorylation
	Electron Transport Chain

4 Reactome Pathways for NDUFB2

	Respiratory electron transport
	Metabolism
	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
	The citric acid (TCA) cycle and respiratory electron transport

5 Kegg Pathways (Kegg details for NDUFB2):

	Oxidative phosphorylation
	Metabolic pathways
	Alzheimer's disease
	Parkinson's disease
	Huntington's disease

NDUFB2 for pathways About GeneDecksing

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for NDUFB2

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/56 Interacting proteins for NDUFB2 (ENSP00000247866⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 56)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
NDUFC1	ENSP00000377770⁴	STRING: ENSP00000377770 STRING: ENSP00000265500
CYC1	ENSP00000317159⁴	STRING: ENSP00000317159
ENSG00000267059	ENSP00000262946⁴	STRING: ENSP00000262946
MT-ND1	ENSP00000354687⁴	STRING: ENSP00000354687
MT-ND2	ENSP00000355046⁴	STRING: ENSP00000355046

About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006120	mitochondrial electron transport, NADH to ubiquinone	NAS	9878551
GO:0022904	respiratory electron transport chain	TAS	--
GO:0044281	small molecule metabolic process	TAS	--

NDUFB2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for NDUFB2

8 HMDB Compounds for NDUFB2 About this table

Compound	Synonyms	CAS #	PubMed Ids
FAD	1H-Purin-6-amine flavin dinucleotide (see all 21)	146-14-5	--
Iron	Armco iron (see all 19)	7439-89-6	--
NAD	3-Carbamoyl-1-D-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate (see all 28)	53-84-9	--
NADH	1,4-Dihydronicotinamide adenine dinucleotide (see all 17)	58-68-4	--
QH2	CoQH2 (see all 5)	56275-39-9	--
Sulfide	Sulfide (see all 4)	18496-25-8	--
Ubiquinone Q1	Coenzyme Q (see all 9)	727-81-1	--
Ubiquinone Q2	2-(3,7-dimethyl-2,6-octadienyl)-5,6-dimethoxy-3-methyl-2,5-Cyclohexadiene-1,4-dione (see all 7)	606-06-4	--

1 DrugBank Compound for NDUFB2 About this table

Compound	Synonyms	CAS #	Type	Actions	PubMed Ids
NADH	beta-DPNH (see all 18)	606-68-8	target	--	17139284 17016423

Search CenterWatch for drugs/clinical trials and news about NDUFB2 / NDUB2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for NDUFB2 gene:

NM_004546.2

Unigene Cluster for NDUFB2:

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa

Hs.655788 [show with all ESTs]

Unigene Representative Sequence: BC065735

17 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000482954 ENST00000476279 ENST00000247866(uc003vwa.3) ENST00000461457

ENST00000465506 ENST00000535972 ENST00000464564 ENST00000476181(uc010lnl.3)

ENST00000464566 ENST00000460088 ENST00000472695 ENST00000476470 ENST00000471136

ENST00000462847 ENST00000475276 ENST00000479181 ENST00000204307

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Additional cDNA sequence:

AF050639.1 AF067166.1 BC001168.1 BC063026.1 BC065735.1 CR542121.1

17 DOTS entries:

DT.97861846 DT.456322 DT.112008 DT.412400 DT.75196070 DT.100038043 DT.100697142 DT.91753052

DT.95149881 DT.95336912 DT.121078780 DT.121078796 DT.100685623 DT.40114578 DT.87015699 DT.95258699

DT.456076

24/415 AceView cDNA sequences (see all 415):

BQ417476 BE739250 BU159967 BU732455 AI340073 AI017674 CB110719 AA341428

CA425711 CR610566 AI279760 AI625407 AI951871 BM511845 AF050639 CB267348

AF067166 F19165 AA593450 BE745459 F21673 NM_052853 CA430229 F18891

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for NDUFB2 About this scheme

ExUns:	1a	·	1b	^	2	^	3a	·	3b	·	3c	^	4a	·	4b	^	5	^	6a	·	6b
SP1:							-								-		-
SP2:					-		-
SP3:															-		-
SP4:															-

ECgene alternative splicing isoforms for NDUFB2

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

NDUFB2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACTCAGAAGA

About this image

NDUFB2 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

3 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Bone

Endochondral Facial Bones

Bone

Thoracic Rib

Bone

Gut Tube

Ventral Foregut Endoderm

Gut Tube

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See NDUFB2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NDUFB2

SOURCE GeneReport for Unigene cluster: Hs.655788

SABiosciences Expression via Pathway-Focused PCR Array including NDUFB2:

Mitochondrial Energy Metabolism in human mouse rat

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for NDUFB2 gene from 6/14 species (see all 14) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Ndufb2^{1 , 5}	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, more^{1, 5}	81.9(n)¹ 82.86(a)¹		6 (18.42 cM)⁵ 68198¹ NM_026612.3¹ NP_080888.1¹ 39592574⁵
chicken (Gallus gallus)	Aves	NDUFB2¹	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, more	67.02(n) 72.63(a)		418118 XM_416351.3 XP_416351.1
lizard (Anolis carolinensis)	Reptilia	NDUFB2⁶	--	66(a)	1 ↔ 1	5(15585783-15587138)
African clawed frog (Xenopus laevis)	Amphibia	ndufb2-prov²	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, more	75.17(n)		BC041535.1
zebrafish (Danio rerio)	Actinopterygii	zgc:73329¹	zgc:73329	60.48(n) 52.58(a)		393764 NM_001167826.1 NP_001161298.1
fruit fly (Drosophila melanogaster)	Insecta	CG40002⁶ CG40472⁶	--	29(a) 29(a)	many → 1 many → 1	3LHet(459586-460458) 3LHet(410462-411042)

ENSEMBL Gene Tree for NDUFB2 (if available)
TreeFam Gene Tree for NDUFB2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for NDUFB2 gene

1 SIMAP similar gene for NDUFB2 using alignment to 8 protein entries: NDUB2_HUMAN (see all proteins):

WUGSC

NDUFB2 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for NDUFB2
PGOHUM00000246109

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 7 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs202005282^1,2		--	140394645(+)	`GGAGGA/CCACTC`	3	--	ds500¹ ut3¹ us2k¹		0	--	--	--	--
rs184023766^1,2	C,	--	140394647(+)	`AGGCCA/TCTCCC`	3	--	us2k¹ ut3¹ ds500¹		0	--	--	--	--
rs73736521^1,2	C,	--	140394775(+)	`AAAAGC/ATTTGG`	3	--	us2k¹ ut3¹ ds500¹		2		WA	120
rs188625215^1,2		--	140394849(+)	`GCCAGG/TGACAC`	3	--	ut3¹ ds500¹ us2k¹		0	--	--	--	--
rs144332599^1,2		--	140395030(+)	`ATGTG-/CACACAC`	3	--	us2k¹ ds500¹ int¹		0	--	--	--	--
rs192998320^1,2		--	140395133(+)	`CAAATG/TATCTT`	3	--	us2k¹ ds500¹ int¹		0	--	--	--	--
rs185593500^1,2		--	140395181(+)	`AACTTC/TTATTA`	3	--	us2k¹ nc-transcript-variantint¹		0	--	--	--	--
rs190518693^1,2		--	140395231(+)	`GGGACA/GTGAGC`	3	--	us2k¹ nc-transcript-variantint¹		0	--	--	--	--
rs150643841^1,2		--	140395279(+)	`TCACCC/TGCTAG`	3	--	nc-transcript-variantint¹ us2k¹		0	--	--	--	--
rs138510909^1,2	C,	--	140395621(+)	`GTCTT-/AAGAGA`	2	--	nc-transcript-variantus2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for NDUFB2 (140390577 - 140422590 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for NDUFB2: --

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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NDUFB2 for disorders           About GeneDecksing

OMIM gene information: 603838    OMIM disorders: --

6 diseases for NDUFB2:    About MalaCards

intraneural perineurioma perineurioma huntington's disease parkinson's disease

ischemia prostatitis

Human Genome Epidemiology (HuGE) Navigator: NDUFB2 (2 documents)

Export disorders for NDUFB2 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for NDUFB2 gene, integrated from 9 sources (see all 14):
(articles sorted by number of sources associating them with NDUFB2)

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world of online information

cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed. (PubMed id 9878551)^{1, 2, 3} Loeffen J.L....Smeitink J.A. (1998)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification. (PubMed id 12611891)^{1, 2} Murray J.... Capaldi R.A. (2003)
Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)^{1, 2} Zhang Q.-H.... Chen Z. (2000)
Intron based radiation hybrid mapping of 15 complex I genes of the human electron transport chain. (PubMed id 9763677)^{1, 3} Emahazion T....Brookes A.J. (1998)
Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)¹ Hendrickson S.L....O'Brien S.J. (2010)
Global profiling of protease cleavage sites by chemos elective labeling of protein N-termini. (PubMed id 19892738)² Xu G....Jaffrey S.R. (2009)
Polymorphisms in mitochondrial genes and prostate can cer risk. (PubMed id 19064571)¹ Wang L....Thibodeau S.N. (2008)
Drugs, their targets and the nature and number of dru g targets. (PubMed id 17016423)⁷ Imming P....Meyer A. (2006)
How many drug targets are there? (PubMed id 17139284)⁷ Overington J.P....Hopkins A.L. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 4708	HGNC: 7697	AceView: NDUFB2andADCK2	Ensembl:ENSG00000090266	euGenes: HUgn4708
ECgene: NDUFB2	Kegg: 4708	H-InvDB: NDUFB2

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for NDUFB2	Pharmacogenomics, SNPs, Pathways

Intellectual Property for NDUFB2 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for NDUFB2 gene:
Search GeneIP for patents involving NDUFB2

GeneCards and IP:
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NDUFB2 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa

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NDUFB2 Gene

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa

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