Aliases for NDUFB11 Gene
External Ids for NDUFB11 Gene
Previous GeneCards Identifiers for NDUFB11 Gene
NDUFB11 is a component of mitochondrial complex I. Complex I catalyzes the first step in the electron transport chain, the transfer of 2 electrons from NADH to ubiquinone, coupled to the translocation of 4 protons across the membrane (Carroll et al., 2002 [PubMed 12381726]).[supplied by OMIM, Feb 2009]
GeneCards Summary for NDUFB11 Gene
NDUFB11 (NADH:Ubiquinone Oxidoreductase Subunit B11) is a Protein Coding gene. Diseases associated with NDUFB11 include Linear Skin Defects With Multiple Congenital Anomalies 3 and Linear Skin Defects With Multiple Congenital Anomalies 1. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. and Metabolism.
UniProtKB/Swiss-Prot for NDUFB11 Gene
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.