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NDUFB11 Gene

protein-coding   GIFtS: 54
GCID: GC0XM047001

NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 11, 17.3kDa

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 11, 17.3kDa1 2     NP17.32
Complex I NP17.3 Subunit1 2     Np152
Complex I-ESSS2 3     P17.32
Neuronal Protein 17.32 3     NADH Dehydrogenase [Ubiquinone] 1 Beta Subcomplex Subunit 11,
Mitochondrial2
CI-ESSS2 3     Np17.33
NADH-Ubiquinone Oxidoreductase ESSS Subunit2 3     p17.33
ESSS2     

External Ids:    HGNC: 203721   Entrez Gene: 545392   Ensembl: ENSG000001471237   OMIM: 3004035   UniProtKB: Q9NX143   

Export aliases for NDUFB11 gene to outside databases

Previous GC identifers: GC0XM046757 GC0XM046886 GC0XM044714


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for NDUFB11 Gene:
NDUFB11 is a component of mitochondrial complex I. Complex I catalyzes the first step in the electron transport
chain, the transfer of 2 electrons from NADH to ubiquinone, coupled to the translocation of 4 protons across the
membrane (Carroll et al., 2002 (PubMed 12381726)).(supplied by OMIM, Feb 2009)

GeneCards Summary for NDUFB11 Gene:
NDUFB11 (NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa) is a protein-coding gene. Diseases associated with NDUFB11 include stiff-person syndrome, and toxic encephalopathy.

UniProtKB/Swiss-Prot: NDUBB_HUMAN, Q9NX14
Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that
is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the
respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Gene Wiki entry for NDUFB11 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000023.11  NC_018934.2  NT_079573.5  
Regulatory elements:
   Regulatory transcription factor binding sites in the NDUFB11 gene promoter:
         ER-alpha   C/EBPbeta   p53   MyoD   Nkx2-5   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNDUFB11 promoter sequence
   Search Chromatin IP Primers for NDUFB11

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NDUFB11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp11.23   Ensembl cytogenetic band:  Xp11.23   HGNC cytogenetic band: Xp11.3

NDUFB11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NDUFB11 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM047001:  view genomic region     (about GC identifiers)

Start:
47,001,615 bp from pter      End:
47,004,903 bp from pter
Size:
3,289 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: NDUBB_HUMAN, Q9NX14 (See protein sequence)
Recommended Name: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial precursor  
Size: 153 amino acids; 17317 Da
Subunit: Complex I is composed of 45 different subunits
Secondary accessions: Q5JRR3 Q5JRR4 Q6IAB6 Q8WZ96 Q9BXX9
Alternative splicing: 2 isoforms:  Q9NX14-1   Q9NX14-2   

Explore the universe of human proteins at neXtProt for NDUFB11: NX_Q9NX14

Explore proteomics data for NDUFB11 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys46
  • Modification sites at PhosphoSitePlus

  • See NDUFB11 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001129470.1  NP_061929.2  

    ENSEMBL proteins: 
     ENSP00000367042   ENSP00000276062  
    Reactome Protein details: Q9NX14

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    comI: Mitochondrial respiratory chain complex / Complex I

    1 InterPro protein domain:
     IPR019329 NADH_UbQ_OxRdtase_ESSS_su

    Graphical View of Domain Structure for InterPro Entry Q9NX14

    ProtoNet protein and cluster: Q9NX14

    UniProtKB/Swiss-Prot: NDUBB_HUMAN, Q9NX14
    Similarity: Belongs to the complex I NDUFB11 subunit family


    NDUFB11 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NDUBB_HUMAN, Q9NX14
    Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that
    is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the
    respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

    Animal Models:

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    2 qRT-PCR Assays for microRNAs that regulate NDUFB11:
    hsa-miR-526b hsa-miR-103a-2*
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NDUBB_HUMAN, Q9NX14: Mitochondrion inner membrane; Single-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    cytoskeleton2
    extracellular2
    nucleus2
    plasma membrane2
    cytosol1
    endoplasmic reticulum1
    golgi apparatus1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ----
    GO:0005743mitochondrial inner membrane TAS--
    GO:0005747mitochondrial respiratory chain complex I IDA12611891
    GO:0016021integral component of membrane IEA--

    NDUFB11 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for NDUFB11 About    
    See pathways by source

    SuperPathContained pathways About
    1Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.0.81
    Parkinson's disease0.57
    Respiratory electron transport0.81
    Huntington's disease0.45
    The citric acid (TCA) cycle and respiratory electron transport0.71
    Non-alcoholic fatty liver disease (NAFLD)0.41
    Oxidative phosphorylation0.64
    2Metabolism
    Metabolism0.38
    Metabolic pathways0.38
    3Alzheimer's disease
    Alzheimer's disease0.44

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Reactome Pathway for NDUFB11
        Respiratory electron transport


    Selected Kegg Pathways  (Kegg details for NDUFB11) (see all 6):
        Oxidative phosphorylation
    Metabolic pathways
    Non-alcoholic fatty liver disease (NAFLD)
    Alzheimer's disease
    Parkinson's disease


    NDUFB11 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NDUFB11
    Interactions:

        Search GeneGlobe Interaction Network for NDUFB11

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for NDUFB11 (Q9NX142, 3 ENSP000002760624) via UniProtKB, MINT, STRING, and/or I2D (see all 67)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CRELD2Q6UXH12, 3MINT-8263599 I2D: score=1 
    BAG6P463793I2D: score=1 
    ENSG00000096155P463793I2D: score=1 
    ENSG00000227761P463793I2D: score=1 
    ENSG00000228760P463793I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0022904respiratory electron transport chain TAS--
    GO:0044237cellular metabolic process TAS--
    GO:0044281small molecule metabolic process TAS--

    NDUFB11 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
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    Browse Tocris compounds for NDUFB11 (NDUBB)

    8 HMDB Compounds for NDUFB11    About this table
    CompoundSynonyms CAS #PubMed Ids
    FAD1H-Purin-6-amine flavin dinucleotide (see all 21)146-14-5--
    IronArmco iron (see all 19)7439-89-6--
    NAD3-Carbamoyl-1-D-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate (see all 28)53-84-9--
    NADH1,4-Dihydronicotinamide adenine dinucleotide (see all 17)58-68-4--
    QH2CoQH2 (see all 5)56275-39-9--
    SulfideSulfide (see all 4)18496-25-8--
    Ubiquinone Q1Coenzyme Q (see all 9)727-81-1--
    Ubiquinone Q22-(3,7-dimethyl-2,6-octadienyl)-5,6-dimethoxy-3-methyl-2,5-Cyclohexadiene-1,4-dione (see all 7)606-06-4--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for NDUFB11 gene (2 alternative transcripts): 
    NM_001135998.2  NM_019056.6  

    Unigene Cluster for NDUFB11:

    NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
    Hs.521969  [show with all ESTs]
    Unigene Representative Sequence: BQ278575
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000377811(uc004dhc.3 uc004dhd.3) ENST00000276062

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    hsa-miR-526b hsa-miR-103a-2*
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    Additional mRNA sequence: 

    AF044213.1 AF134476.1 AF251063.1 AK000501.1 AY359056.1 BC010665.1 BC107805.1 CR457239.1 

    7 DOTS entries:

    DT.454683  DT.95208019  DT.100756555  DT.101984296  DT.100889292  DT.95076739  DT.121282105 

    Selected AceView cDNA sequences (see all 276):

    AJ346376 BQ057397 BM841002 BU509402 BM699244 BQ925073 BM665264 AA523612 
    AW161413 CB127595 BQ670209 BM708792 AY359056 BU848622 BU730764 BF594004 
    BI712757 BM702552 CB125437 CK820903 BM709096 BQ676341 AI653431 BM703437 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for NDUFB11    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3
    SP1:                    -         
    SP2:                              


    ECgene alternative splicing isoforms for NDUFB11

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NDUFB11 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAATCCAACT
    NDUFB11 Expression
    About this image


    NDUFB11 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 8) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Neural Tube (Nervous System)
             Diencephalon
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
    NDUFB11 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NDUFB11 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.521969

    UniProtKB/Swiss-Prot: NDUBB_HUMAN, Q9NX14
    Tissue specificity: Ubiquitous

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NDUFB11

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for NDUFB11 gene from Selected species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ndufb111 , 5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, more1, 5 82.12(n)1
    77.48(a)1
      X (16.11 cM)5
    1041301  NM_019435.41  NP_062308.21 
     206153265 
    zebrafish
    (Danio rerio)
    Actinopterygii ndufb111 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, more 54.32(n)
    46.67(a)
      562219  NM_001044981.1  NP_001038446.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta NP15.66
    NP15.6
    26(a)
    1 ↔ 1
    3R(14853074-14853737)


    ENSEMBL Gene Tree for NDUFB11 (if available)
    TreeFam Gene Tree for NDUFB11 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NDUFB11 gene

    NDUFB11 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for NDUFB11
    PGOHUM00000242424


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NDUFB11 (see all 21)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1864537101,2
    --47001169(+) GGGAGA/GTGGAG 2 -- int10--------
    rs1499130481,2
    --47001515(+) CAGCAA/GTATAC 2 -- int10--------
    rs736302561,2
    C,F--47001611(+) ACTAGT/CGAGTC 2 -- int11Minor allele frequency- C:0.00WA 2
    rs2006559691,2
    --47001686(+) AAGGCA/GGTGCT 2 -- ut310--------
    rs1997267681,2
    --47001818(+) GCTTCA/GCGGCG 4 R syn10--------
    rs1912757871,2
    C--47001991(+) TCCCAC/TGCTCT 3 A syn1 int10--------
    rs2018861241,2
    --47002007(+) ACCCTA/GTGCAC 3 T I mis1 int10--------
    rs1826010591,2
    C--47002024(+) TCAGGC/GAGATA 4 L syn10--------
    rs105301,2
    C--47002096(+) ATGTTC/TCAGAC 4 * W stg1 ese36Minor allele frequency- T:0.00NA EA MN 440
    rs1864694641,2
    C--47002101(+) CCAGAC/TGTCCA 4 I V mis10--------

    HapMap Linkage Disequilibrium report for NDUFB11 (47001615 - 47004903 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for NDUFB11: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NDUFB11
    DNA2.0 Custom Variant and Variant Library Synthesis for NDUFB11

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 300403    OMIM disorders: --

    19 diseases for NDUFB11:    
    About MalaCards
    stiff-person syndrome    toxic encephalopathy    lewy body dementia    endometrial stromal sarcoma
    leber hereditary optic neuropathy    neuronitis    dementia    huntington's disease
    tonsillitis    fatty liver disease    neuropathy    parkinson's disease
    sarcoma    alzheimer's disease    liver disease    neuroblastoma
    cerebritis    thyroiditis    prostatitis

    2 diseases from the University of Copenhagen DISEASES database for NDUFB11:
    Parkinson's disease     Lewy body dementia

    NDUFB11 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    Export disorders for NDUFB11 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NDUFB11 gene, integrated from 10 sources (see all 20):
    (articles sorted by number of sources associating them with NDUFB11)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and tissue expressional characterization of a full-length cDNA encoding human neuronal protein P17.3. (PubMed id 10544803)1, 2, 3 Cui Y.... Zhao S. (Biochem. Genet. 1999)
    2. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (Nature 2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification. (PubMed id 12611891)1, 2 Murray J.... Capaldi R.A. (J. Biol. Chem. 2003)
    6. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    7. Definition of the nuclear encoded protein composition of bovine heart mitochondrial complex I. Identification of two new subunits. (PubMed id 12381726)1, 3 Carroll J....Hirst J. (J. Biol. Chem. 2002)
    8. The NDUFB11 gene is not a modifier in Leber hereditary optic neuropathy. (PubMed id 17292333)1, 9 Petruzzella V....Santorelli F.M. (Biochem. Biophys. Res. Commun. 2007)
    9. The mechanism of alternative splicing of the X-linked NDUFB11 gene of the respiratory chain complex I, impact of rotenone treatment in neuroblastoma cells. (PubMed id 23246602)1 Panelli D....Papa S. (Biochim. Biophys. Acta 2013)
    10. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54539 HGNC: 20372 AceView: NDUFB11 Ensembl:ENSG00000147123 euGenes: HUgn54539
    ECgene: NDUFB11 Kegg: 54539 H-InvDB: NDUFB11

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NDUFB11 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NDUFB11 gene:
    Search GeneIP for patents involving NDUFB11

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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