Aliases for NDUFB11 Gene
External Ids for NDUFB11 Gene
Previous GeneCards Identifiers for NDUFB11 Gene
The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is located at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to ubiquinone. Mutations in the human gene are associated with linear skin defects with multiple congenital anomalies 3 and mitochondrial complex I deficiency. [provided by RefSeq, Dec 2016]
GeneCards Summary for NDUFB11 Gene
NDUFB11 (NADH:Ubiquinone Oxidoreductase Subunit B11) is a Protein Coding gene. Diseases associated with NDUFB11 include Linear Skin Defects With Multiple Congenital Anomalies 3 and Linear Skin Defects With Multiple Congenital Anomalies 1. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. and GABAergic synapse.
UniProtKB/Swiss-Prot for NDUFB11 Gene
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.