Aliases for NDUFB11 Gene
External Ids for NDUFB11 Gene
Previous GeneCards Identifiers for NDUFB11 Gene
NDUFB11 is a component of mitochondrial complex I. Complex I catalyzes the first step in the electron transport chain, the transfer of 2 electrons from NADH to ubiquinone, coupled to the translocation of 4 protons across the membrane (Carroll et al., 2002 [PubMed 12381726]).[supplied by OMIM, Feb 2009]
GeneCards Summary for NDUFB11 Gene
NDUFB11 (NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 11, 17.3kDa) is a Protein Coding gene. Diseases associated with NDUFB11 include linear skin defects with multiple congenital anomalies 3 and endometrial stromal tumor. Among its related pathways are Metabolism and Alzheimers disease.
UniProtKB/Swiss-Prot for NDUFB11 Gene
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone