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NDUFB10 Gene

protein-coding   GIFtS: 58
GCID: GC16P002112

NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 10, 22kDa

(Previous names: NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10 (22kD,...)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 10, 22kDa1 2     NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 10 (22kD, PDSW)1
Complex I PDSW Subunit1 2     PDSW2
Complex I-PDSW2 3     NADH Dehydrogenase [Ubiquinone] 1 Beta Subcomplex Subunit 102
CI-PDSW2 3     NADH Ubiquinone Oxidoreductase PDSW Subunit (RH 16p13.3)2
NADH-Ubiquinone Oxidoreductase PDSW Subunit2 3     

External Ids:    HGNC: 76961   Entrez Gene: 47162   Ensembl: ENSG000001409907   OMIM: 6038435   UniProtKB: O960003   

Export aliases for NDUFB10 gene to outside databases

Previous GC identifers: GC16P002026 GC16P001949 GC16P002014 GC16P001933 GC16P002023 GC16P002027 GC16P002030 GC16P002053 GC16P002074 GC16P002091


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for NDUFB10 Gene:
NDUFB10 (NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa) is a protein-coding gene. GO annotations related to this gene include NADH dehydrogenase (ubiquinone) activity.

UniProtKB/Swiss-Prot: NDUBA_HUMAN, O96000
Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that
is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the
respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Gene Wiki entry for NDUFB10 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000016.9  NC_018927.2  NT_010393.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the NDUFB10 gene promoter:
         HEN1   NF-1/L   NF-1   MAZR   Pax-5   MyoD   Nkx2-5   NF-kappaB1   c-Ets-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNDUFB10 promoter sequence
   Search Chromatin IP Primers for NDUFB10

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NDUFB10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p13.3   Ensembl cytogenetic band:  16p13.3   HGNC cytogenetic band: 16p13.3

NDUFB10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NDUFB10 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P002112:  view genomic region     (about GC identifiers)

Start:
2,009,509 bp from pter      End:
2,011,976 bp from pter
Size:
2,468 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: NDUBA_HUMAN, O96000 (See protein sequence)
Recommended Name: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10  
Size: 172 amino acids; 20777 Da
Subunit: Complex I is composed of 45 different subunits

Explore the universe of human proteins at neXtProt for NDUFB10: NX_O96000

Explore proteomics data for NDUFB10 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys91, Lys121, Lys131
  • Modification sites at PhosphoSitePlus

  • See NDUFB10 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_004539.1  
    ENSEMBL proteins: 
     ENSP00000268668   ENSP00000445086   ENSP00000455348   ENSP00000457908  
    Reactome Protein details: O96000

    NDUFB10 Human Recombinant Protein Products:

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    Browse Proteins at Cloud-Clone Corp.

     
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    antibodies-online proteins for NDUFB10 (5 products) 

     
    antibodies-online peptides for NDUFB10

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    comI: Mitochondrial respiratory chain complex / Complex I

    1 InterPro protein domain:
     IPR019377 NADH_UbQ_OxRdtase_su10

    Graphical View of Domain Structure for InterPro Entry O96000

    ProtoNet protein and cluster: O96000

    UniProtKB/Swiss-Prot: NDUBA_HUMAN, O96000
    Similarity: Belongs to the complex I NDUFB10 subunit family


    Find genes that share domains with NDUFB10           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NDUBA_HUMAN, O96000
    Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that
    is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the
    respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

         Genatlas biochemistry entry for NDUFB10:
    NADH ubiquinone oxidoreductase (Q reductase),22kDa,component beta 10,hydrophobic fraction of the complex I
    multi-subunit enzyme of the oxidative phosphorylation (OXPHOS),inner mitochondrial membrane

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI14557246
    GO:0008137NADH dehydrogenase (ubiquinone) activity NAS9878551
         
    Find genes that share ontologies with NDUFB10           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for NDUFB10

    miRNA
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    miRTarBase miRNAs that target NDUFB10:
    hsa-mir-92a-3p (MIRT049618), hsa-mir-132-3p (MIRT021832), hsa-mir-744-5p (MIRT037561)

    Block miRNA regulation of human, mouse, rat NDUFB10 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate NDUFB10:
    hsa-miR-205*
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    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NDUBA_HUMAN, O96000: Mitochondrion inner membrane; Peripheral membrane protein; Matrix side
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    cytosol2
    extracellular2
    nucleus1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ----
    GO:0005743mitochondrial inner membrane TAS--
    GO:0005747mitochondrial respiratory chain complex I NAS9878551

    Find genes that share ontologies with NDUFB10           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for NDUFB10 About    
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.0.81
    Parkinson's disease0.57
    Respiratory electron transport0.81
    Oxidative phosphorylation0.51
    Electron Transport Chain0.75
    Huntington's disease0.45
    The citric acid (TCA) cycle and respiratory electron transport0.71
    Non-alcoholic fatty liver disease (NAFLD)0.41
    2Metabolism
    Metabolism0.38
    Metabolic pathways0.38
    3Alzheimer's disease
    Alzheimer's disease0.44


    Find genes that share SuperPaths with NDUFB10           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 BioSystems Pathways for NDUFB10
        Oxidative phosphorylation
    Electron Transport Chain


    1 Reactome Pathway for NDUFB10
        Respiratory electron transport


    Selected Kegg Pathways  (Kegg details for NDUFB10) (see all 6):
        Oxidative phosphorylation
    Metabolic pathways
    Non-alcoholic fatty liver disease (NAFLD)
    Alzheimer's disease
    Parkinson's disease

        Pathway & Disease-focused RT2 Profiler PCR Array including NDUFB10: 
              Mitochondrial Energy Metabolism in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for NDUFB10

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for NDUFB10 (O960003 ENSP000002686684) via UniProtKB, MINT, STRING, and/or I2D (see all 120)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NDUFA2O436783, ENSP000002521024I2D: score=1 STRING: ENSP00000252102
    HTR2AP282233, ENSP000003679594I2D: score=1 STRING: ENSP00000367959
    TSC1Q925743, ENSP000002985524I2D: score=2 STRING: ENSP00000298552
    UBE2DNLQ8IWF73I2D: score=1 
    NDUFC1ENSP000003777704STRING: ENSP00000377770 STRING: ENSP00000265500
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006120mitochondrial electron transport, NADH to ubiquinone NAS9878551
    GO:0022904respiratory electron transport chain TAS--
    GO:0044237cellular metabolic process TAS--
    GO:0044281small molecule metabolic process TAS--

    Find genes that share ontologies with NDUFB10           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NDUFB10 (NDUBA)

    8 HMDB Compounds for NDUFB10    About this table
    CompoundSynonyms CAS #PubMed Ids
    FAD1H-Purin-6-amine flavin dinucleotide (see all 21)146-14-5--
    IronArmco iron (see all 19)7439-89-6--
    NAD3-Carbamoyl-1-D-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate (see all 28)53-84-9--
    NADH1,4-Dihydronicotinamide adenine dinucleotide (see all 17)58-68-4--
    QH2CoQH2 (see all 5)56275-39-9--
    SulfideSulfide (see all 4)18496-25-8--
    Ubiquinone Q1Coenzyme Q (see all 9)727-81-1--
    Ubiquinone Q22-(3,7-dimethyl-2,6-octadienyl)-5,6-dimethoxy-3-methyl-2,5-Cyclohexadiene-1,4-dione (see all 7)606-06-4--

    1 DrugBank Compound for NDUFB10    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    NADHbeta-DPNH (see all 18)606-68-8target--17139284 17016423



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for NDUFB10 gene: 
    NM_004548.2  

    Unigene Cluster for NDUFB10:

    NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa
    Hs.513266  [show with all ESTs]
    Unigene Representative Sequence: BQ278464
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000268668(uc002cni.2) ENST00000543683(uc002cnj.2) ENST00000565031
    ENST00000569148 ENST00000570172
    miRNA
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    hsa-miR-205*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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      QuantiTect SYBR Green Assays in human, mouse, rat NDUFB10
      QuantiFast Probe-based Assays in human, mouse, rat NDUFB10

    Additional mRNA sequence: 

    AF044954.1 AF067169.1 AF088991.1 AK291876.1 AK311744.1 BC005829.2 BC007509.2 

    13 DOTS entries:

    DT.99982850  DT.97859587  DT.417504  DT.100035315  DT.120702516  DT.95278230  DT.100747916  DT.95278227 
    DT.120702603  DT.95278228  DT.120702621  DT.121638967  DT.120702583 

    Selected AceView cDNA sequences (see all 252):

    BU509665 BU730837 F24732 BM912844 CD366977 BQ013874 BM564771 BM549529 
    BU838289 BQ929618 BM708541 BM696092 F24311 BE391452 BG757972 BM663481 
    BQ949294 BQ421745 BF724546 BE552287 BC005829 AI621255 BE311640 BM840197 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for NDUFB10    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4
    SP1:                                -         
    SP2:                                -         
    SP3:                                          


    ECgene alternative splicing isoforms for NDUFB10

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NDUFB10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAGCAGAGGC
    NDUFB10 Expression
    About this image


    NDUFB10 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Bone (Muscoskeletal System)
             Membranous Facial Bones
     
     Eye (Sensory Organs)
             Lens
     
     Neural Tube (Nervous System)
             Telencephalon
    NDUFB10 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NDUFB10 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.513266
        Pathway & Disease-focused RT2 Profiler PCR Array including NDUFB10: 
              Mitochondrial Energy Metabolism in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NDUFB10

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for NDUFB10 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ndufb101 , 5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, more1, 5 80.54(n)1
    82.61(a)1
      17 (12.51 cM)5
    683421  NM_026684.21  NP_080960.11 
     247220605 
    chicken
    (Gallus gallus)
    Aves NDUFB101 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, more 67.29(n)
    58.12(a)
      416543  XM_414844.4  XP_414844.1 
    lizard
    (Anolis carolinensis)
    Reptilia NDUFB106
    NADH dehydrogenase (ubiquinone) 1 beta subcomplex,...
    50(a)
    1 ↔ 1
    GL344276.1(97714-101490)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.214052 Xenopus laevis transcribed sequence with weak similarity more 76.77(n)    AW643467.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc731472 hypothetical protein MGC73147 73.27(n)   393703  BC059507.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Pdsw1 Pdsw 51.08(n)
    31.65(a)
      44228  NM_164537.1  NP_722908.1 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_F59C6.51 CELE_F59C6.5 43.97(n)
    36.17(a)
      172933  NM_060351.4  NP_492752.1 


    ENSEMBL Gene Tree for NDUFB10 (if available)
    TreeFam Gene Tree for NDUFB10 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NDUFB10 gene

    Find genes that share paralogs with NDUFB10           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for NDUFB10
    PGOHUM00000246796 PGOHUM00000262494


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

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    Selected SNPs for NDUFB10 (see all 166)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1484837181,2
    --2007552(+) TAAGGC/TGCCGC 1 -- us2k10--------
    rs1998303291,2
    C--2007554(+) AGGCG-/CCGCGCG 1 -- us2k10--------
    rs116412271,2
    C,F,H--2007560(+) cgcgcG/Atctgg 1 -- us2k1 tfbs38Minor allele frequency- A:0.36NA CSA WA EA 368
    rs1426543781,2
    --2007567(+) CTGGAA/GTTGTT 1 -- us2k10--------
    rs1509363331,2
    --2007578(+) CATCCC/TGCCAG 1 -- us2k10--------
    rs1394763101,2
    --2007603(+) CACTGC/GCTTCA 1 -- us2k10--------
    rs1149352451,2
    C,F--2007607(+) GGCTTC/TAGGAG 1 -- us2k11Minor allele frequency- T:0.07WA 118
    rs1441885101,2
    C--2007623(+) CTGCAA/GATCTT 1 -- us2k10--------
    rs1855072641,2
    --2007665(+) TGTGAC/TCCCAA 1 -- us2k10--------
    rs1478093731,2
    --2007719(+) AAGCTC/TCCACA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for NDUFB10 (2009509 - 2011976 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for NDUFB10 (see all 17):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2422427CNV Duplication17116639
    dgv2545n71CNV Loss21882294
    dgv2546n71CNV Loss21882294
    nsv905048CNV Loss21882294
    dgv2551n71CNV Loss21882294
    dgv2540n71CNV Loss21882294
    nsv905061CNV Loss21882294
    dgv2547n71CNV Loss21882294
    nsv833120CNV Loss17160897
    nsv519366CNV Loss19592680

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

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    OMIM gene information: 603843    OMIM disorders: --


    Find genes that share disorders with NDUFB10           About GenesLikeMe

    Genetic Association Database (GAD): NDUFB10
    Human Genome Epidemiology (HuGE) Navigator: NDUFB10 (3 documents)

    Export disorders for NDUFB10 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

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    PubMed articles for NDUFB10 gene, integrated from 10 sources (see all 29):
    (articles sorted by number of sources associating them with NDUFB10)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed. (PubMed id 9878551)1, 2, 3 Loeffen J.L.C.M.... Smeitink J.A.M. (Biochem. Biophys. Res. Commun. 1998)
    2. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    3. Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey. (PubMed id 18977241)1, 4 Starr J.M....Deary I.J. (Mech. Ageing Dev. 2008)
    4. A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition. (PubMed id 17601350)1, 4 Harris S.E....Deary I.J. (BMC Genet. 2007)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification. (PubMed id 12611891)1, 2 Murray J.... Capaldi R.A. (J. Biol. Chem. 2003)
    7. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (Genome Res. 2000)
    8. Intron based radiation hybrid mapping of 15 complex I genes of the human electron transport chain. (PubMed id 9763677)1, 3 Emahazion T....Brookes A.J. (Cytogenet. Cell Genet. 1998)
    9. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    10. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 4716 HGNC: 7696 AceView: NDUFB10 Ensembl:ENSG00000140990 euGenes: HUgn4716
    ECgene: NDUFB10 Kegg: 4716 H-InvDB: NDUFB10

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for NDUFB10 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for NDUFB10 gene:
    Search GeneIP for patents involving NDUFB10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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