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NDUFAF5 Gene

protein-coding   GIFtS: 40
GCID: GC20P013765

NADH Dehydrogenase (Ubiquinone) Complex I, Assembly Factor...

(Previous name: chromosome 20 open reading frame 7)
(Previous symbol: C20orf7)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
NADH Dehydrogenase (Ubiquinone) Complex I, Assembly Factor 51 2     bA526K24.22
C20orf71 2 3 5     dJ842G6.12
Probable Methyltransferase C20orf7, Mitochondrial2 3     NADH Dehydrogenase [Ubiquinone] 1 Alpha Subcomplex Assembly Factor 52
Chromosome 20 Open Reading Frame 71     EC 2.1.1.-3

External Ids:    HGNC: 158991   Entrez Gene: 791332   Ensembl: ENSG000001012477   OMIM: 6123605   UniProtKB: Q5TEU43   

Export aliases for NDUFAF5 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for NDUFAF5 Gene:
The NADH-ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory chain catalyzes the
transfer of electrons from NADH to ubiquinone, and consists of at least 43 subunits. The complex is located in
the inner mitochondrial membrane. This gene encodes a mitochondrial protein that is associated with the matrix
face of the mitochondrial inner membrane and is required for complex I assembly. A mutation in this gene results
in mitochondrial complex I deficiency. Multiple transcript variants encoding different isoforms have been found
for this gene. (provided by RefSeq, Oct 2009)

GeneCards Summary for NDUFAF5 Gene:
NDUFAF5 (NADH dehydrogenase (ubiquinone) complex I, assembly factor 5) is a protein-coding gene. Diseases associated with NDUFAF5 include mitochondrial complex i deficiency, and dysphagia. GO annotations related to this gene include methyltransferase activity.

UniProtKB/Swiss-Prot: NDUF5_HUMAN, Q5TEU4
Function: Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I, MT-ND1) at
early stages. May have methyltransferase activity




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000020.11  NT_011387.9  NC_018931.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for NDUFAF5
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for NDUFAF5

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NDUFAF5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20p12.1   Ensembl cytogenetic band:  20p12.1   HGNC cytogenetic band: 20p12.1

NDUFAF5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NDUFAF5 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P013765:  view genomic region     (about GC identifiers)

Start:
13,765,596 bp from pter      End:
13,799,067 bp from pter
Size:
33,472 bases      Orientation:
plus strand
ORGUL member locations:
Legend (see complete legend)

ORGUL Member Locations for NDUFAF5

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: NDUF5_HUMAN, Q5TEU4 (See protein sequence)
Recommended Name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5 precursor  
Size: 345 amino acids; 38918 Da
Secondary accessions: A8K166 Q6GPH3 Q9H6F4
Alternative splicing: 2 isoforms:  Q5TEU4-1   Q5TEU4-2   

Explore the universe of human proteins at neXtProt for NDUFAF5: NX_Q5TEU4

Explore proteomics data for NDUFAF5 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys109
  • Modification sites at PhosphoSitePlus

  • See NDUFAF5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001034464.1  NP_077025.2  

    ENSEMBL proteins: 
     ENSP00000367346   ENSP00000437325   ENSP00000420497  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    MITOAF: Mitochondrial respiratory chain complex assembly factors

    1 InterPro protein domain:
     IPR013216 Methyltransf_11

    Graphical View of Domain Structure for InterPro Entry Q5TEU4

    ProtoNet protein and cluster: Q5TEU4

    UniProtKB/Swiss-Prot: NDUF5_HUMAN, Q5TEU4
    Similarity: Belongs to the methyltransferase superfamily


    NDUFAF5 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NDUF5_HUMAN, Q5TEU4
    Function: Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I, MT-ND1) at
    early stages. May have methyltransferase activity

         Enzyme Number (IUBMB): EC 2.1.1.-1

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0008168methyltransferase activity IEA--
         
    NDUFAF5 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for NDUFAF5:
     Increased S DNA content 

    Animal Models:
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NDUF5_HUMAN, Q5TEU4: Mitochondrion inner membrane. Note=Peripherally localized on the matrix face of the
    mitochondrial inner membrane

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ----
    GO:0031314extrinsic component of mitochondrial inner membrane IDA18940309

    NDUFAF5 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NDUFAF5
    Interactions:

        Search GeneGlobe Interaction Network for NDUFAF5

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for NDUFAF5 (ENSP000003673464) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PYURFENSP000002739684STRING: ENSP00000273968
    C14orf1ENSP000002563194STRING: ENSP00000256319
    NDUFAF6ENSP000003794304STRING: ENSP00000379430
    C4orf27ENSP000004065984STRING: ENSP00000406598
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008152metabolic process ----
    GO:0032981mitochondrial respiratory chain complex I assembly IMP18940309

    NDUFAF5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NDUFAF5 (NDUF5)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for NDUFAF5 gene (3 alternative transcripts): 
    NM_001039375.2  NM_024120.4  NM_199052.1  

    Unigene Cluster for NDUFAF5:

    NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
    Hs.472165  [show with all ESTs]
    Unigene Representative Sequence: NR_029377
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000378106(uc002wom.3 uc002won.3) ENST00000378081(uc002woo.3)
    ENST00000463598 ENST00000485738 ENST00000477732 ENST00000481249 ENST00000475968
    ENST00000476536 ENST00000469177 ENST00000464269 ENST00000479716 ENST00000487478
    ENST00000476124 ENST00000476200 ENST00000479682 ENST00000486772

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    Additional mRNA sequence: 

    AK025977.1 AK091060.1 AK289781.1 BC005984.1 BC073158.1 NR_029377.1 

    10 DOTS entries:

    DT.85105308  DT.95259716  DT.92034894  DT.102823103  DT.120823219  DT.95371830  DT.120823192  DT.447033 
    DT.95371833  DT.97800701 

    Selected AceView cDNA sequences (see all 99):

    CB241105 BM351906 BG026315 BQ574799 AA329532 BQ435974 BE267189 AI332694 
    AA789132 BM679902 CB156360 AL522176 BM981516 AA830093 W37089 BX280231 
    AI379944 CR616637 CF528534 BC073158 AI000893 NM_199052 BP870897 AW576362 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for NDUFAF5 (see all 10)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b · 8c ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b
    SP1:                                -     -     -                 -                                         -                                       
    SP2:                                -     -     -                 -                                         -           -                           
    SP3:                                -     -     -                             -                             -           -                           
    SP4:                                -     -     -                                                                                                   
    SP5:                                -     -     -                 -                       -                                                         


    ECgene alternative splicing isoforms for NDUFAF5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NDUFAF5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    NDUFAF5 Expression
    About this image

    NDUFAF5 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NDUFAF5 Protein Expression

    Genevestigator expression for NDUFAF5

    SOURCE GeneReport for Unigene cluster: Hs.472165
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NDUFAF5 gene from Selected species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ndufaf51 , 5 RIKEN cDNA 2310003L22 gene5
    NADH dehydrogenase (ubiquinone) complex I, assembly more1
    84.55(n)1
    84.84(a)1
      2 (69.20 cM)5
    694871  NM_027093.41  NP_081369.21 
     1401706495 
    chicken
    (Gallus gallus)
    Aves C20ORF71 chromosome 3 open reading frame, human C20orf7 72.12(n)
    74.69(a)
      416742  NM_001278083.1  NP_001265012.1 
    lizard
    (Anolis carolinensis)
    Reptilia NDUFAF56
    NADH dehydrogenase (ubiquinone) complex I, assembl...
    75(a)
    1 ↔ 1
    1(129332701-129343404)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.172212 Transcribed sequence with moderate similarity to protein more 75.12(n)    142014163 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.158972 Transcribed sequence with moderate similarity to protein more 75.59(n)    BM534541.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG80671 CG8067 54.95(n)
    54.73(a)
      36552  NM_001274031.1  NP_001260960.1 
    worm
    (Caenorhabditis elegans)
    Secernentea K09E4.31 K09E4.3 53.82(n)
    52.43(a)
      175064  NM_001267487.1  NP_001254416.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G228001 AT1G22800 51.98(n)
    45.8(a)
      838886  NM_102127.3  NP_173694.1 


    ENSEMBL Gene Tree for NDUFAF5 (if available)
    TreeFam Gene Tree for NDUFAF5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NDUFAF5 (see all 868)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0541194
    Mitochondrial complex I deficiency (MT-C1D)4--see VAR_0541192 L P mis40--------
    VAR_0679564
    Leigh syndrome (LS)4--see VAR_0679562 L F mis40--------
    rs1404363451,2
    F--13715344(+) TTTGAC/TTTTTC 3 -- us2k11Minor allele frequency- T:0.00NA 4550
    rs1441621191,2
    --13715349(+) CTTTTC/TGATCC 3 -- us2k10--------
    rs1999927811,2
    C--13715389(+) CTTTGC/TAACCC 3 -- us2k11Minor allele frequency- T:0.00EU 1291
    rs1995545211,2
    C--13715405(+) AACCGC/G/TTGGTC 3 -- us2k10--------
    rs1827533091,2
    C--13715462(+) CCAAAC/TGCTTG 3 -- us2k10--------
    rs1877988101,2
    --13715488(+) GAAAAA/GTAAAA 3 -- us2k10--------
    rs2006824211,2
    --13715546(+) AAACA-/CATT  
            
    CATTC
    3 -- us2k10--------
    rs283729641,2
    C--13715547(-) TGAAT-/AAT   
      T
    /TAAT
    GTGTT
    3 -- us2k11CSA 2

    HapMap Linkage Disequilibrium report for NDUFAF5 (13765596 - 13799067 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for NDUFAF5: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NDUFAF5
    DNA2.0 Custom Variant and Variant Library Synthesis for NDUFAF5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612360   
    OMIM disorders: 252010  
    UniProtKB/Swiss-Prot: NDUF5_HUMAN, Q5TEU4
  • Mitochondrial complex I deficiency (MT-C1D) [MIM:252010]: A disorder of the mitochondrial respiratory
    chain that causes a wide range of clinical manifestations from lethal neonatal disease to adult-onset
    neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific
    encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and
    some forms of Parkinson disease. Note=The disease is caused by mutations affecting the gene represented in this
    entry
  • Leigh syndrome (LS) [MIM:256000]: An early-onset progressive neurodegenerative disorder characterized by
    the presence of focal, bilateral lesions in one or more areas of the central nervous system including the
    brainstem, thalamus, basal ganglia, cerebellum and spinal cord. Clinical features depend on which areas of the
    central nervous system are involved and include subacute onset of psychomotor retardation, hypotonia, ataxia,
    weakness, vision loss, eye movement abnormalities, seizures, and dysphagia. Note=The disease is caused by
    mutations affecting the gene represented in this entry

  • 15 diseases for NDUFAF5:    About MalaCards
    mitochondrial complex i deficiency    dysphagia    leber hereditary optic neuropathy    leukodystrophy
    hypotonia    intrahepatic cholangiocarcinoma    cholangiocarcinoma    neuropathy
    myopathy    liver disease    ataxia    parkinson's disease
    multiple myeloma    malaria    myeloma


    NDUFAF5 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    Export disorders for NDUFAF5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NDUFAF5 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with NDUFAF5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Mutation of C20orf7 disrupts complex I assembly and causes lethal neonatal mitochondrial disease. (PubMed id 18940309)1, 2, 3 Sugiana C.... Thorburn D.R. (Am. J. Hum. Genet. 2008)
    2. Combined OXPHOS complex I and IV defect, due to mutated complex I assembly factor C20ORF7. (PubMed id 21607760)1, 3 Saada A....Elpeleg O. (J. Inherit. Metab. Dis. 2012)
    3. Defective complex I assembly due to C20orf7 mutations as a new cause of Leigh syndrome. (PubMed id 19542079)1, 2 Gerards M.... Smeets H.J. (J. Med. Genet. 2010)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    6. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    7. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
    8. Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. (PubMed id 16712791)1 Wang A.G....Kim N.S. (Biochem. Biophys. Res. Commun. 2006)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79133 HGNC: 15899 AceView: C20orf7 Ensembl:ENSG00000101247 euGenes: HUgn79133
    ECgene: NDUFAF5 H-InvDB: NDUFAF5

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NDUFAF5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NDUFAF5 gene:
    Search GeneIP for patents involving NDUFAF5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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