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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NDUFAF4 Gene

protein-coding   GIFtS: 53
GCID: GC06M097337

NADH Dehydrogenase (Ubiquinone) Complex I, Assembly Factor...

(Previous names: chromosome 6 open reading frame 66, NADH dehydrogenase (ubiquinone)...)
(Previous symbol: C6orf66)
Alzheimer's & Parkinson's Diseases Congress
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
NADH Dehydrogenase (Ubiquinone) Complex I, Assembly Factor 41 2     Chromosome 6 Open Reading Frame 661
C6orf661 2 3 5     My0132
HRPAP202 3 5     bA22L21.12
NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex, Assembly Factor 41 2     Hormone-Regulated Proliferation-Associated Protein, 20 KDa2
Hormone-Regulated Proliferation-Associated Protein Of 20 KDa2 3     NADH Dehydrogenase [Ubiquinone] 1 Alpha Subcomplex Assembly Factor 42

External Ids:    HGNC: 210341   Entrez Gene: 290782   Ensembl: ENSG000001235457   OMIM: 6117765   UniProtKB: Q9P0323   

Export aliases for NDUFAF4 gene to outside databases

Previous GC identifers: GC06M097446 GC06M094771


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NDUFAF4 Gene:
NADH:ubiquinone oxidoreductase (complex I) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme
Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the
inner mitochondrial membrane. This gene encodes a complex I assembly factor. Mutations in this gene are a cause
of mitochondrial complex I deficiency. (provided by RefSeq, Oct 2009)

GeneCards Summary for NDUFAF4 Gene: 
NDUFAF4 (NADH dehydrogenase (ubiquinone) complex I, assembly factor 4) is a protein-coding gene. Diseases associated with NDUFAF4 include mitochondrial complex i deficiency, and leber hereditary optic neuropathy. GO annotations related to this gene include protein binding and calmodulin binding.

UniProtKB/Swiss-Prot: NDUF4_HUMAN, Q9P032
Function: Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). May be
involved in cell proliferation and survival of hormone-dependent tumor cells. May be a regulator of breast tumor
cell invasion




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.2  NT_025741.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NDUFAF4 gene promoter:
         Bach1   POU3F2 (N-Oct-5b)   POU3F2 (N-Oct-5a)   AREB6   POU2F1   POU2F1b   POU2F1a   POU2F1c   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for NDUFAF4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NDUFAF4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q16.1   Ensembl cytogenetic band:  6q16.1   HGNC cytogenetic band: 6q16.3

NDUFAF4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NDUFAF4 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M097337:  view genomic region     (about GC identifiers)

Start:
97,337,187 bp from pter      End:
97,345,767 bp from pter
Size:
8,581 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NDUF4_HUMAN, Q9P032 (See protein sequence)
Recommended Name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4  
Size: 175 amino acids; 20266 Da
Subunit: Binds calmodulin. Interacts with NDUFAF3
Subcellular location: Mitochondrion
Secondary accessions: B2R4J5

Explore the universe of human proteins at neXtProt for NDUFAF4: NX_Q9P032

Explore proteomics data for NDUFAF4 at MOPED 

Post-translational modifications:

  • UniProtKB: Phosphorylated on serine. Prolactin stimulate serine phosphorylation (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9P032

  • NDUFAF4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NDUFAF4 Protein Expression
    REFSEQ proteins: NP_054884.1  
    ENSEMBL proteins: 
     ENSP00000358272  

    Human Recombinant Protein Products for NDUFAF4: 
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    ProSpec Recombinant Protein for NDUFAF4
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IDA--
    GO:0031966mitochondrial membrane IDA19463981

    NDUFAF4 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    MITOAF: Mitochondrial respiratory chain complex assembly factors

    1 InterPro protein domain:
     IPR009622 UPF0240

    Graphical View of Domain Structure for InterPro Entry Q9P032

    ProtoNet protein and cluster: Q9P032

    1 Blocks protein domain: IPB009622 Protein of unknown function UPF0240

    UniProtKB/Swiss-Prot: NDUF4_HUMAN, Q9P032
    Similarity: Belongs to the NDUFAF4 family


    NDUFAF4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NDUF4_HUMAN, Q9P032
    Function: Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). May be
    involved in cell proliferation and survival of hormone-dependent tumor cells. May be a regulator of breast tumor
    cell invasion
    Induction: Expression is low in quiescent cells and is induced in exponentially proliferating cultures. Expression
    is also induced when prolactin is added to stationary cells. Induced by dietary differentiating agents such as
    butyrate and retinoic acid

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI19463981
    GO:0005516calmodulin binding IEA--
         
    NDUFAF4 for ontologies           About GeneDecksing


    Animal Models:
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NDUFAF4

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    3 Interacting proteins for NDUFAF4 (Q9P0323 ENSP000003582724) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NDUFAF3Q9BU613, ENSP000003230764I2D: score=1 STRING: ENSP00000323076
    SQSTM1Q135013I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0032981mitochondrial respiratory chain complex I assembly IMP18179882

    NDUFAF4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NDUFAF4 (NDUF4)

    1 HMDB Compound for NDUFAF4    About this table
    CompoundSynonyms CAS #PubMed Ids
    NADH1,4-Dihydronicotinamide adenine dinucleotide (see all 17)58-68-4--

    Search CenterWatch for drugs/clinical trials and news about NDUFAF4 / NDUF4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NDUFAF4 gene: 
    NM_014165.3  

    Unigene Cluster for NDUFAF4:

    NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
    Hs.512144  [show with all ESTs]
    Unigene Representative Sequence: NM_014165
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000316149(uc003pov.3 uc003pow.3) ENST00000478382 ENST00000489477


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    hsa-miR-146a* hsa-miR-455-5p hsa-miR-24 hsa-miR-548aa
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    Inhib. RNA
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    Additional mRNA sequence: 

    AF060508.1 AF161474.1 AK026245.1 AK311850.1 BC018802.1 BC039464.1 

    6 DOTS entries:

    DT.86840984  DT.95272254  DT.97818658  DT.100780837  DT.121346749  DT.95281487 

    24/147 AceView cDNA sequences (see all 147):

    BF112035 AI187014 AI660691 CB140302 BI963019 AI075248 CK903618 BX096390 
    AI084350 AI864185 CB159598 AA846350 BM689589 AI042346 AA706679 AA974334 
    AI222429 AI589148 BF577051 CB157886 BE644639 AI266447 BC039464 CK023868 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for NDUFAF4    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b · 5c · 5d
    SP1:              -     -     -                                       
    SP2:              -     -     -           -                           
    SP3:                    -     -           -                           
    SP4:                          -           -                           
    SP5:                                      -                           


    ECgene alternative splicing isoforms for NDUFAF4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NDUFAF4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCAAGAGCCG
    NDUFAF4 Expression
    About this image


    See NDUFAF4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NDUFAF4

    SOURCE GeneReport for Unigene cluster: Hs.512144
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for NDUFAF4 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ndufaf41 , 5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, more1, 5 79.58(n)1
    72.83(a)1
      4 (10.52 cM)5
    684931  NM_026742.41  NP_081018.11 
     248980835 
    chicken
    (Gallus gallus)
    Aves NDUFAF41 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, more 61.57(n)
    51.18(a)
      421802  XM_003641013.1  XP_003641061.1 
    lizard
    (Anolis carolinensis)
    Reptilia NDUFAF46
    Uncharacterized protein
    48(a)
    1 ↔ 1
    1(173582119-173585828)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.333492 Xenopus laevis transcribed sequence with weak similarity more 76.87(n)    BI477869.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ndufaf41 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, more 55.1(n)
    47.06(a)
      794169  XM_003200655.1  XP_003200703.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG117221 CG11722 46.06(n)
    36.36(a)
      41227  NM_141713.3  NP_649970.1 


    ENSEMBL Gene Tree for NDUFAF4 (if available)
    TreeFam Gene Tree for NDUFAF4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NDUFAF4 gene

    NDUFAF4 for paralogs           About GeneDecksing


    4 Pseudogenes.org Pseudogenes for NDUFAF4
    PGOHUM00000247112 PGOHUM00000244344 PGOHUM00000237588 PGOHUM00000233471


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/219 SNPs in NDUFAF4 are shown (see all 219)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0443294
    Mitochondrial complex I deficiency (MT-C1D)4--see VAR_0443292 L P mis40--------
    rs637510611,2
    Cpathogenic197343597(-) GTTTCC/TAAAAG 2 P L mis10--------
    rs624152811,2
    C,F--97335618(+) CAGGCG/ATCTCC 1 -- ds50013Minor allele frequency- A:0.03NA EA 242
    rs1489534191,2
    --97335670(+) CCAGAA/GTTCTA 1 -- ds50010--------
    rs1145055221,2
    C,F--97335693(+) ATATAC/G/TGGTGA 1 -- ds50011WA 118
    rs1841263801,2
    --97335732(+) TCAGGA/CACTTT 1 -- ds50010--------
    rs1436797781,2
    --97335744(+) CATGAA/CATCTC 1 -- ds50010--------
    rs1886366981,2
    --97335782(+) ACATAA/GCGTAT 1 -- ds50010--------
    rs1913163531,2
    --97335783(+) CATAGC/TGTATC 1 -- ds50010--------
    rs1510300031,2
    --97335944(+) ATACAC/TGTAAA 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for NDUFAF4 (97337187 - 97345767 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for NDUFAF4:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv886425CNV Loss21882294


    Human Gene Mutation Database (HGMD): NDUFAF4
    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611776   
    OMIM disorders: 252010  
    UniProtKB/Swiss-Prot: NDUF4_HUMAN, Q9P032
  • Mitochondrial complex I deficiency (MT-C1D) [MIM:252010]: A disorder of the mitochondrial respiratory
    chain that causes a wide range of clinical manifestations from lethal neonatal disease to adult-onset
    neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific
    encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and
    some forms of Parkinson disease. Note=The disease is caused by mutations affecting the gene represented in this
    entry

  • 11 diseases for NDUFAF4:    About MalaCards
    mitochondrial complex i deficiency    leber hereditary optic neuropathy    encephalomyopathy    mitochondrial encephalomyopathy
    leukodystrophy    neuropathy    parkinson's disease    myopathy
    liver disease    thyroiditis    breast cancer

    1 disease from the University of Copenhagen DISEASES database for NDUFAF4:
    Mitochondrial encephalomyopathy

    NDUFAF4 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): NDUFAF4
    Human Genome Epidemiology (HuGE) Navigator: NDUFAF4 (1 document)

    Export disorders for NDUFAF4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NDUFAF4 gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with NDUFAF4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. C6ORF66 is an assembly factor of mitochondrial complex I. (PubMed id 18179882)1, 2, 3 Saada A.... Elpeleg O. (2008)
    2. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2, 3 Zhang Q.-H.... Chen Z. (2000)
    3. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    4. Mutations in NDUFAF3 (C3ORF60), encoding an NDUFAF4 (C6ORF66)- interacting complex I assembly protein, cause fatal neonatal mitochondrial disease. (PubMed id 19463981)1, 2 Saada A....Nijtmans L.G. (2009)
    5. HRPAP20: a novel calmodulin-binding protein that increases breast cancer cell invasion. (PubMed id 17001319)1, 2 Karp C.M.... Buckley A.R. (2007)
    6. Identification of HRPAP20: a novel phosphoprotein that enhances growth and survival in hormone-responsive tumor cells. (PubMed id 14871833)1, 2 Karp C.M.... Buckley A.R. (2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    9. Oligonucleotide microarray analysis of estrogen receptor alpha-positive postmenopausal breast carcinomas: identification of HRPAP20 and TIMELESS as outstanding candidate markers to predict the response to tamoxifen. (PubMed id 17909269)1, 9 Tozlu-Kara S....Bieche I. (2007)
    10. Replacement of the C6ORF66 Assembly Factor (NDUFAF4) R estores Complex I Activity in Patient Cells. (PubMed id 23670274)1 Marcus D....Lorberboum-Galski H. (2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 29078 HGNC: 21034 AceView: C6orf66 Ensembl:ENSG00000123545 euGenes: HUgn29078
    ECgene: NDUFAF4 H-InvDB: NDUFAF4

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NDUFAF4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NDUFAF4 gene:
    Search GeneIP for patents involving NDUFAF4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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